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Molecular Pharmacology

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Table of Contents

November 01, 2004; Volume 66,Issue 5

Minireview

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    Ca2+ Channels As Integrators of G Protein-Mediated Signaling in Neurons
    Jesse Strock and María A. Diversé-Pierluissi
    Molecular Pharmacology November 2004, 66 (5) 1071-1076; DOI: https://doi.org/10.1124/mol.104.002261

Perspective

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    The Ants Go Marching Two by Two: Oligomeric Structure of G-Protein-Coupled Receptors
    Jonathan A. Javitch
    Molecular Pharmacology November 2004, 66 (5) 1077-1082; DOI: https://doi.org/10.1124/mol.104.006320

Articles

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    Transcriptional Response to Corticotropin-Releasing Factor in AtT-20 Cells
    Pieter J. Peeters, Hinrich W. Göhlmann, Ilse Van den Wyngaert, Sigrid M. Swagemakers, Luc Bijnens, Stefan U. Kass and Thomas Steckler
    Molecular Pharmacology November 2004, 66 (5) 1083-1092; DOI: https://doi.org/10.1124/mol.104.000950
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    A Common Antitussive Drug, Clobutinol, Precipitates the Long QT Syndrome 2
    Chloé Bellocq, Ronald Wilders, Jean-Jacques Schott, Bénédicte Louérat-Oriou, Pierre Boisseau, Hervé Le Marec, Denis Escande and Isabelle Baró
    Molecular Pharmacology November 2004, 66 (5) 1093-1102; DOI: https://doi.org/10.1124/mol.104.001065
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    Mapping of Maurotoxin Binding Sites on hKv1.2, hKv1.3, and hIKCa1 Channels
    Violeta Visan, Ziad Fajloun, Jean-Marc Sabatier and Stephan Grissmer
    Molecular Pharmacology November 2004, 66 (5) 1103-1112; DOI: https://doi.org/10.1124/mol.104.002774
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    An Investigation of the Neuroprotective Effects of Tetracycline Derivatives in Experimental Models of Retinal Cell Death
    Darryl C. Baptiste, Andrew T. E. Hartwick, Christine A. B. Jollimore, William H. Baldridge, Gail M. Seigel and Melanie E. M. Kelly
    Molecular Pharmacology November 2004, 66 (5) 1113-1122; DOI: https://doi.org/10.1124/mol.104.001081
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    Multiple Interactions between Transmembrane Helices Generate the Oligomeric α1b-Adrenoceptor
    Juan J. Carrillo, Juan F. López-Giménez and Graeme Milligan
    Molecular Pharmacology November 2004, 66 (5) 1123-1137; DOI: https://doi.org/10.1124/mol.104.001586
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    Biological Activity of the G-Quadruplex Ligand RHPS4 (3,11-Difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate) Is Associated with Telomere Capping Alteration
    Carlo Leonetti, Sarah Amodei, Carmen D'Angelo, Angela Rizzo, Barbara Benassi, Anna Antonelli, Raffaella Elli, Malcolm F. G. Stevens, Maurizio D'Incalci, Gabriella Zupi and Annamaria Biroccio
    Molecular Pharmacology November 2004, 66 (5) 1138-1146; DOI: https://doi.org/10.1124/mol.104.001537
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    Specific Inhibition of Nuclear Factor-κB–Dependent Inflammatory Responses by Cell Type-Specific Mechanisms upon A2A Adenosine Receptor Gene Transfer
    William A. Sands, Anthony F. Martin, Elaine W. Strong and Timothy M. Palmer
    Molecular Pharmacology November 2004, 66 (5) 1147-1159; DOI: https://doi.org/10.1124/mol.104.001107
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    Targeting Ischemic Stroke with a Novel Opener of ATP-Sensitive Potassium Channels in the Brain
    Hai Wang, Ying-li Zhang, Xing-Chun Tang, Hua-Song Feng and Gang Hu
    Molecular Pharmacology November 2004, 66 (5) 1160-1168; DOI: https://doi.org/10.1124/mol.104.003178
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    A Three-Dimensional Model for the Substrate Binding Domain of the Multidrug ATP Binding Cassette Transporter LmrA
    Gerhard F. Ecker, Karin Pleban, Stephan Kopp, Edina Csaszar, Gerrit J. Poelarends, Monique Putman, Dominik Kaiser, Wil N. Konings and Peter Chiba
    Molecular Pharmacology November 2004, 66 (5) 1169-1179; DOI: https://doi.org/10.1124/mol.104.001420
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    The Catecholamine Release-Inhibitory “Catestatin” Fragment of Chromogranin A: Naturally Occurring Human Variants with Different Potencies for Multiple Chromaffin Cell Nicotinic Cholinergic Responses
    Sushil K. Mahata, Manjula Mahata, Gen Wen, William B. Wong, Nitish R. Mahapatra, Bruce A. Hamilton and Daniel T. O'Connor
    Molecular Pharmacology November 2004, 66 (5) 1180-1191; DOI: https://doi.org/10.1124/mol.104.002139
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    A Model of Inverse Agonist Action at Thyrotropin-Releasing Hormone Receptor Type 1: Role of a Conserved Tryptophan in Helix 6
    Xinping Lu, Wei Huang, Sharon Worthington, Piotr Drabik, Roman Osman and Marvin C. Gershengorn
    Molecular Pharmacology November 2004, 66 (5) 1192-1200; DOI: https://doi.org/10.1124/mol.104.000349
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    The Low-Potency, Voltage-Dependent HERG Blocker Propafenone—Molecular Determinants and Drug Trapping
    Harry J. Witchel, Christopher E. Dempsey, Richard B. Sessions, Matthew Perry, James T. Milnes, Jules C. Hancox and John S. Mitcheson
    Molecular Pharmacology November 2004, 66 (5) 1201-1212; DOI: https://doi.org/10.1124/mol.104.001743
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    A Novel Nonpeptide Ligand for Formyl Peptide Receptor-Like 1
    Masakatsu Nanamori, Xiyuan Cheng, Jianghua Mei, Hairong Sang, Yunxia Xuan, Caihong Zhou, Ming-Wei Wang and Richard D. Ye
    Molecular Pharmacology November 2004, 66 (5) 1213-1222; DOI: https://doi.org/10.1124/mol.104.004309
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    5β-Reduced Neuroactive Steroids Are Novel Voltage-Dependent Blockers of T-Type Ca2+ Channels in Rat Sensory Neurons in Vitro and Potent Peripheral Analgesics in Vivo
    Slobodan M. Todorovic, Sriyani Pathirathna, Barbara C. Brimelow, Miljen M. Jagodic, Seong-Hoon Ko, Xin Jiang, Kent R. Nilsson, Charles F. Zorumski, Douglas F. Covey and Vesna Jevtovic-Todorovic
    Molecular Pharmacology November 2004, 66 (5) 1223-1235; DOI: https://doi.org/10.1124/mol.104.002402
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    Molecular Determinants of Frequency Dependence and Ca2+ Potentiation of Verapamil Block in the Pore Region of Cav1.2
    Nejmi Dilmac, Nathan Hilliard and Gregory H. Hockerman
    Molecular Pharmacology November 2004, 66 (5) 1236-1247; DOI: https://doi.org/10.1124/mol.104.000893
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    Molecular Dissection of the Butyrate Action Revealed the Involvement of Mitogen-Activated Protein Kinase in Cystic Fibrosis Transmembrane Conductance Regulator Biogenesis
    Makoto Sugita, Hiroyasu Kongo and Yoshiki Shiba
    Molecular Pharmacology November 2004, 66 (5) 1248-1259; DOI: https://doi.org/10.1124/mol.104.001008
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    RNA Interference Suggests a Primary Role for Monoacylglycerol Lipase in the Degradation of the Endocannabinoid 2-Arachidonoylglycerol
    Thien P. Dinh, Satish Kathuria and Daniele Piomelli
    Molecular Pharmacology November 2004, 66 (5) 1260-1264; DOI: https://doi.org/10.1124/mol.104.002071
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    Cloning, Up-Regulation, and Mitogenic Role of Porcine P2Y2 Receptor in Coronary Artery Smooth Muscle Cells
    Jianzhong Shen, Cheikh I. Seye, Meifang Wang, Gary A. Weisman, Peter A. Wilden and Michael Sturek
    Molecular Pharmacology November 2004, 66 (5) 1265-1274; DOI: https://doi.org/10.1124/mol.104.002642
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    Long-Term Administration of Δ9-Tetrahydrocannabinol Desensitizes CB1-, Adenosine A1-, and GABAB-Mediated Inhibition of Adenylyl Cyclase in Mouse Cerebellum
    Dana E. Selley, Michael P. Cassidy, Billy R. Martin and Laura J. Sim-Selley
    Molecular Pharmacology November 2004, 66 (5) 1275-1284; DOI: https://doi.org/10.1124/mol.104.000604
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    Role of mPKCI, a Novel μ-Opioid Receptor Interactive Protein, in Receptor Desensitization, Phosphorylation, and Morphine-Induced Analgesia
    Wei Guang, Hongyan Wang, Tao Su, I. Bernard Weinstein and Jia Bei Wang
    Molecular Pharmacology November 2004, 66 (5) 1285-1292; DOI: https://doi.org/10.1124/mol.66.5.1285
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    His452Tyr Polymorphism in the Human 5-HT2A Receptor Destabilizes the Signaling Conformation
    Lisa A. Hazelwood and Elaine Sanders-Bush
    Molecular Pharmacology November 2004, 66 (5) 1293-1300; DOI: https://doi.org/10.1124/mol.66.5.1293
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    p53 Elevation in Relation to Levels and Cytotoxicity of Mono- and Bifunctional Melphalan-DNA Adducts
    Katherine A. Gould, Cally Nixon and Michael J. Tilby
    Molecular Pharmacology November 2004, 66 (5) 1301-1309; DOI: https://doi.org/10.1124/mol.104.000596
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    Kinin B1 Receptors Stimulate Nitric Oxide Production in Endothelial Cells: Signaling Pathways Activated by Angiotensin I-Converting Enzyme Inhibitors and Peptide Ligands
    Tatjana Ignjatovic, Sinisa Stanisavljevic, Viktor Brovkovych, Randal A. Skidgel and Ervin G. Erdos
    Molecular Pharmacology November 2004, 66 (5) 1310-1316; DOI: https://doi.org/10.1124/mol.104.001990
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    RNF4 Is a Coactivator for Nuclear Factor Y on GTP Cyclohydrolase I Proximal Promoter
    Sheng-Ming Wu, Wen-Chih Kuo, Wuh-Liang Hwu, Kuo-Yuan Hwa, Roberto Mantovani and Yu-May Lee
    Molecular Pharmacology November 2004, 66 (5) 1317-1324; DOI: https://doi.org/10.1124/mol.66.5.1317
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    Reciprocal Signaling between the Transcriptional Co-Factor Eya2 and Specific Members of the Gαi Family
    Alan C. Embry, Jennifer L. Glick, Maurine E. Linder and Patrick J. Casey
    Molecular Pharmacology November 2004, 66 (5) 1325-1331; DOI: https://doi.org/10.1124/mol.104.004093
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    Modulation of Cellular Cholesterol Alters P-Glycoprotein Activity in Multidrug-Resistant Cells
    Joachim Troost, Heike Lindenmaier, Walter Emil Haefeli and Johanna Weiss
    Molecular Pharmacology November 2004, 66 (5) 1332-1339; DOI: https://doi.org/10.1124/mol.104.002329
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    The Involvement of PTEN in Sleep Deprivation-Induced Memory Impairment in Rats
    Chun-Lin Su, Chun-Hung Chen, Hsin-Yi Lu and Po-Wu Gean
    Molecular Pharmacology November 2004, 66 (5) 1340-1348; DOI: https://doi.org/10.1124/mol.104.001156
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    Protein Thiol Modification by 15-deoxy-Δ12,14-Prostaglandin J2 Addition in Mesangial Cells: Role in the Inhibition of Pro-inflammatory Genes
    Francisco J. Sánchez-Gómez, Eva Cernuda-Morollón, Konstantinos Stamatakis and Dolores Pérez-Sala
    Molecular Pharmacology November 2004, 66 (5) 1349-1358; DOI: https://doi.org/10.1124/mol.104.002824
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    Correction to “Maitotoxin induces biphasic interleukin-1β secretion and membrane blebbing in murine macrophages”
    Molecular Pharmacology November 2004, 66 (5) 1359; DOI: https://doi.org/10.1124/mol.66.5.1359
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Molecular Pharmacology: 66 (5)
Molecular Pharmacology
Vol. 66, Issue 5
1 Nov 2004
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  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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