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Molecular Pharmacology

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Research ArticleORIGINAL ARTICLE

Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2

Anne Frandsen, Darryl S. Pickering, Bente Vestergaard, Christina Kasper, Bettina Bryde Nielsen, Jeremy R. Greenwood, Giuseppe Campiani, Caterina Fattorusso, Michael Gajhede, Arne Schousboe and Jette Sandholm Kastrup
Molecular Pharmacology March 2005, 67 (3) 703-713; DOI: https://doi.org/10.1124/mol.104.002931
Anne Frandsen
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Darryl S. Pickering
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Bente Vestergaard
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Christina Kasper
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Bettina Bryde Nielsen
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Jeremy R. Greenwood
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Giuseppe Campiani
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Caterina Fattorusso
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Michael Gajhede
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Arne Schousboe
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Jette Sandholm Kastrup
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Article Information

vol. 67 no. 3 703-713
DOI 
https://doi.org/10.1124/mol.104.002931
PubMed 
15591246

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received May 24, 2004
  • Accepted December 6, 2004
  • Published online February 16, 2005.

Article Versions

  • Earlier version (December 9, 2004 - 13:42).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Anne Frandsen,
  2. Darryl S. Pickering,
  3. Bente Vestergaard,
  4. Christina Kasper,
  5. Bettina Bryde Nielsen,
  6. Jeremy R. Greenwood,
  7. Giuseppe Campiani,
  8. Caterina Fattorusso,
  9. Michael Gajhede,
  10. Arne Schousboe and
  11. Jette Sandholm Kastrup
  1. Biostructural Research, Department of Medicinal Chemistry (A.F., B.V., C.K., B.B.N., J.R.G., M.G., J.S.K.) and Department of Pharmacology (D.S.P., A.S.), Danish University of Pharmaceutical Sciences, Copenhagen, Denmark; Dipartimento Farmaco Chimico Tecnologico and European Research Centre for Drug Discovery and Development, Siena University, Siena, Italy (G.C.); and Dipartimento di Chimica delle Sostanze Naturali, Napoli University, Napoli, Italy (C.F.)
  1. Address correspondence to:
    Jette Sandholm Kastrup, Department of Medicinal Chemistry, Danish University of Pharmaceutical Sciences, Universitetsparken 2, DK-2100, Copenhagen Ø, Denmark. E-mail: jsk{at}dfuni.dk.
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Molecular Pharmacology: 67 (3)
Molecular Pharmacology
Vol. 67, Issue 3
1 Mar 2005
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Research ArticleORIGINAL ARTICLE

Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2

Anne Frandsen, Darryl S. Pickering, Bente Vestergaard, Christina Kasper, Bettina Bryde Nielsen, Jeremy R. Greenwood, Giuseppe Campiani, Caterina Fattorusso, Michael Gajhede, Arne Schousboe and Jette Sandholm Kastrup
Molecular Pharmacology March 1, 2005, 67 (3) 703-713; DOI: https://doi.org/10.1124/mol.104.002931

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Research ArticleORIGINAL ARTICLE

Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2

Anne Frandsen, Darryl S. Pickering, Bente Vestergaard, Christina Kasper, Bettina Bryde Nielsen, Jeremy R. Greenwood, Giuseppe Campiani, Caterina Fattorusso, Michael Gajhede, Arne Schousboe and Jette Sandholm Kastrup
Molecular Pharmacology March 1, 2005, 67 (3) 703-713; DOI: https://doi.org/10.1124/mol.104.002931
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