Discovery of a Small Molecule Activator of the Human Ether-a-go-go-Related Gene (HERG) Cardiac K+ Channel

Departments of Medicinal Chemistry (M.T.) and Oncology (F.V.) Aventis Pharmaceuticals, Vitry-Sur-Seine, France; and Department of Drug Safety Evaluation, Aventis Pharmaceuticals, Bridgewater, New Jersey (J.K., X.-L.C., H.W., J.J., H.C., J.I., W.R., D.R.)

Address correspondence to:
Dr. David Rampe, Aventis Pharmaceuticals, Inc., Route 202–206, Building JR2-2236, Bridgewater, NJ 08807-0800. E-mail: david.rampe{at}aventis.com

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