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Research ArticleOriginal Article

Pharmacological Differences between Human and Guinea Pig Histamine H1 Receptors: Asn84 (2.61) as Key Residue within an Additional Binding Pocket in the H1 Receptor

Martijn Bruysters, Aldo Jongejan, Michel Gillard, Frank van de Manakker, Remko A. Bakker, Pierre Chatelain and Rob Leurs
Molecular Pharmacology April 2005, 67 (4) 1045-1052; DOI: https://doi.org/10.1124/mol.104.008847

Article Information

vol. 67 no. 4 1045-1052
DOI 
https://doi.org/10.1124/mol.104.008847
PubMed 
15626750
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received October 29, 2004
  • Accepted December 29, 2004
  • Published online March 21, 2005.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Martijn Bruysters,
  2. Aldo Jongejan,
  3. Michel Gillard,
  4. Frank van de Manakker,
  5. Remko A. Bakker,
  6. Pierre Chatelain and
  7. Rob Leurs
  1. Leiden/Amsterdam Center for Drug Research, Faculty of Sciences, Department of Medicinal Chemistry, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands (M.B., A.J., F.v.d.M., R.A.B., R.L.); and UCB S.A. Pharma Sector, Braine-l'Alleud, Belgium (M.G., P.C.)
  1. Address correspondence to:
    Prof. Dr. R. Leurs, Leiden/Amsterdam Center for Drug Research, Faculty of Sciences, Department of Medicinal Chemistry, Vrije Universiteit Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands. E-mail: r.leurs{at}few.vu.nl
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Research ArticleOriginal Article

Pharmacological Differences between Human and Guinea Pig Histamine H1 Receptors: Asn84 (2.61) as Key Residue within an Additional Binding Pocket in the H1 Receptor

Martijn Bruysters, Aldo Jongejan, Michel Gillard, Frank van de Manakker, Remko A. Bakker, Pierre Chatelain and Rob Leurs
Molecular Pharmacology April 1, 2005, 67 (4) 1045-1052; DOI: https://doi.org/10.1124/mol.104.008847
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