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Molecular Pharmacology

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Table of Contents

June 01, 2005; Volume 67,Issue 6

Perspective

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    What's for Lunch at the Conformational Cafeteria?
    William P. Clarke
    Molecular Pharmacology June 2005, 67 (6) 1819-1821; DOI: https://doi.org/10.1124/mol.105.013060

Accelerated Communications

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    Centaurin-α1, an ADP-Ribosylation Factor 6 GTPase Activating Protein, Inhibits β2-Adrenoceptor Internalization
    Joanna Lawrence, Stuart J. Mundell, Hongruo Yun, Eamonn Kelly and Kanamarlapudi Venkateswarlu
    Molecular Pharmacology June 2005, 67 (6) 1822-1828; DOI: https://doi.org/10.1124/mol.105.011338
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    Chemical-Based Translational Induction of Luciferase Expression: An Efficient Tool for in Vivo Screening of Protein Farnesylation Inhibitors
    O. Boijoux, C. Boutonnet, C. Giamarchi, G. Favre, S. Vagner and J. C. Faye
    Molecular Pharmacology June 2005, 67 (6) 1829-1833; DOI: https://doi.org/10.1124/mol.105.011163

Articles

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    Identification of a Potent and Selective Synthetic Agonist at the CRTH2 Receptor
    François G. Gervais, Jean-Pierre Morello, Christian Beaulieu, Nicole Sawyer, Danielle Denis, Gillian Greig, A. Daniel Malebranche and Gary P. O'Neill
    Molecular Pharmacology June 2005, 67 (6) 1834-1839; DOI: https://doi.org/10.1124/mol.104.009068
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    Coupling of Metabotropic Glutamate Receptor 8 to N-Type Ca2+ Channels in Rat Sympathetic Neurons
    Juan Guo and Stephen R. Ikeda
    Molecular Pharmacology June 2005, 67 (6) 1840-1851; DOI: https://doi.org/10.1124/mol.105.010975
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    Suppression of hREV1 Expression Reduces the Rate at Which Human Ovarian Carcinoma Cells Acquire Resistance to Cisplatin
    Tsuyoshi Okuda, Xinjian Lin, Julie Trang and Stephen B. Howell
    Molecular Pharmacology June 2005, 67 (6) 1852-1860; DOI: https://doi.org/10.1124/mol.104.010579
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    Corticosteroids Inhibit Cell Death Induced by Doxorubicin in Cardiomyocytes: Induction of Antiapoptosis, Antioxidant, and Detoxification Genes
    Qin M. Chen, Donnia Alexander, Haipeng Sun, Lifang Xie, Yan Lin, Jerome Terrand, Steve Morrissy and Sally Purdom
    Molecular Pharmacology June 2005, 67 (6) 1861-1873; DOI: https://doi.org/10.1124/mol.104.003814
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    The Crystal Structure of the Complex of the Anticancer Prodrug 7-Ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica Acetylcholinesterase Provides a Molecular Explanation for Its Cholinergic Action
    Michal Harel, Janice L. Hyatt, Boris Brumshtein, Christopher L. Morton, Kyoung Jin P. Yoon, Randy M. Wadkins, Israel Silman, Joel L. Sussman and Philip M. Potter
    Molecular Pharmacology June 2005, 67 (6) 1874-1881; DOI: https://doi.org/10.1124/mol.104.009944
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    The Neurotransmitter Noradrenaline Rescues Septal Cholinergic Neurons in Culture from Degeneration Caused by Low-Level Oxidative Stress
    Sabine Traver, Bénédicte Salthun-Lassalle, Marc Marien, Etienne C. Hirsch, Francis Colpaert and Patrick P. Michel
    Molecular Pharmacology June 2005, 67 (6) 1882-1891; DOI: https://doi.org/10.1124/mol.104.007864
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    Differential Spatial Approximation between Cholecystokinin Residue 30 and Receptor Residues in Active and Inactive Conformations
    Maoqing Dong, Elizabeth M. Hadac, Delia I. Pinon and Laurence J. Miller
    Molecular Pharmacology June 2005, 67 (6) 1892-1900; DOI: https://doi.org/10.1124/mol.105.012179
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    Taipoxin Induces Synaptic Vesicle Exocytosis and Disrupts the Interaction of Synaptophysin I with VAMP2
    Dario Bonanomi, Maria Pennuto, Michela Rigoni, Ornella Rossetto, Cesare Montecucco and Flavia Valtorta
    Molecular Pharmacology June 2005, 67 (6) 1901-1908; DOI: https://doi.org/10.1124/mol.104.005678
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    Endoplasmic Reticulum Stress Links Dyslipidemia to Inhibition of Proteasome Activity and Glucose Transport by HIV Protease Inhibitors
    Rex A. Parker, Oliver P. Flint, Ruth Mulvey, Carolina Elosua, Faye Wang, William Fenderson, Shulin Wang, Wen-Pin Yang and Mustafa A. Noor
    Molecular Pharmacology June 2005, 67 (6) 1909-1919; DOI: https://doi.org/10.1124/mol.104.010165
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    Identification and Characterization of PDE4A11, a Novel, Widely Expressed Long Isoform Encoded by the Human PDE4A cAMP Phosphodiesterase Gene
    Derek A. Wallace, Lee Ann Johnston, Elaine Huston, Douglas MacMaster, Thomas M. Houslay, York-Fong Cheung, Lachlan Campbell, Jenni E. Millen, Robin A. Smith, Irene Gall, Richard G. Knowles, Michael Sullivan and Miles D. Houslay
    Molecular Pharmacology June 2005, 67 (6) 1920-1934; DOI: https://doi.org/10.1124/mol.104.009423
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    Retinoids Potentiate Peroxisome Proliferator-Activated Receptor γ Action in Differentiation, Gene Expression, and Lipid Metabolic Processes in Developing Myeloid Cells
    Attila Szanto and Laszlo Nagy
    Molecular Pharmacology June 2005, 67 (6) 1935-1943; DOI: https://doi.org/10.1124/mol.104.006445
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    Functional Interactions Between Nucleotide Binding Domains and Leukotriene C4 Binding Sites of Multidrug Resistance Protein 1 (ABCC1)
    Lea Payen, Mian Gao, Christopher Westlake, Ashley Theis, Susan P. C. Cole and Roger G. Deeley
    Molecular Pharmacology June 2005, 67 (6) 1944-1953; DOI: https://doi.org/10.1124/mol.104.007708
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    Antimalarial Artemisinin Drugs Induce Cytochrome P450 and MDR1 Expression by Activation of Xenosensors Pregnane X Receptor and Constitutive Androstane Receptor
    Oliver Burk, Katja A. Arnold, Andreas K. Nussler, Elke Schaeffeler, Ekaterina Efimova, Bonnie A. Avery, Mitchell A. Avery, Martin F. Fromm and Michel Eichelbaum
    Molecular Pharmacology June 2005, 67 (6) 1954-1965; DOI: https://doi.org/10.1124/mol.104.009019
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    Mutation of the DRY Motif Reveals Different Structural Requirements for the CC Chemokine Receptor 5-Mediated Signaling and Receptor Endocytosis
    Bernard Lagane, Sébastien Ballet, Thierry Planchenault, Karl Balabanian, Emmanuel Le Poul, Cédric Blanpain, Yann Percherancier, Isabelle Staropoli, Gilbert Vassart, Martin Oppermann, Marc Parmentier and Françoise Bachelerie
    Molecular Pharmacology June 2005, 67 (6) 1966-1976; DOI: https://doi.org/10.1124/mol.104.009779
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    The Effects of Subunit Composition on the Inhibition of Nicotinic Receptors by the Amphipathic Blocker 2,2,6,6-Tetramethylpiperidin-4-yl Heptanoate
    Roger L. Papke, Joshua D. Buhr, Michael M. Francis, Kyung Il Choi, Jeffrey S. Thinschmidt and Nicole A. Horenstein
    Molecular Pharmacology June 2005, 67 (6) 1977-1990; DOI: https://doi.org/10.1124/mol.105.011676
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    Farnesyltransferase Inhibitor BMS-214662 Induces Apoptosis in Myeloma Cells through PUMA Up-Regulation, Bax and Bak Activation, and Mcl-1 Elimination
    María Gómez-Benito, Isabel Marzo, Alberto Anel and Javier Naval
    Molecular Pharmacology June 2005, 67 (6) 1991-1998; DOI: https://doi.org/10.1124/mol.104.007021
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    Breast Cancer Resistance Protein (Bcrp1/Abcg2) Limits Net Intestinal Uptake of Quercetin in Rats by Facilitating Apical Efflux of Glucuronides
    Aloys L. A. Sesink, Ilja C. W. Arts, Vincent C. J. de Boer, Pauline Breedveld, Jan H. M. Schellens, Peter C. H. Hollman and Frans G. M. Russel
    Molecular Pharmacology June 2005, 67 (6) 1999-2006; DOI: https://doi.org/10.1124/mol.104.009753
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    Expression of Nigrostriatal α6-Containing Nicotinic Acetylcholine Receptors Is Selectively Reduced, but Not Eliminated, by β3 Subunit Gene Deletion
    Cecilia Gotti, Milena Moretti, Francesco Clementi, Loredana Riganti, J. Michael McIntosh, Allan C. Collins, Michael J. Marks and Paul Whiteaker
    Molecular Pharmacology June 2005, 67 (6) 2007-2015; DOI: https://doi.org/10.1124/mol.105.011940
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    Chemically Distinct Ligands Promote Differential CB1 Cannabinoid Receptor-Gi Protein Interactions
    Somnath Mukhopadhyay and Allyn C. Howlett
    Molecular Pharmacology June 2005, 67 (6) 2016-2024; DOI: https://doi.org/10.1124/mol.104.003558
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    Neurotensin Stimulates Interleukin-8 Expression through Modulation of IκBα Phosphorylation and p65 Transcriptional Activity: Involvement of Protein Kinase Cα
    Dezheng Zhao, Yanai Zhan, Huiyan Zeng, Hon-Wai Koon, Mary P. Moyer and Charalabos Pothoulakis
    Molecular Pharmacology June 2005, 67 (6) 2025-2031; DOI: https://doi.org/10.1124/mol.104.010801
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    DNA Methylation-Related Chromatin Modification in the Regulation of Mouse δ-Opioid Receptor Gene
    Guilin Wang, Tiancheng Liu, Li-Na Wei, Ping-Yee Law and Horace H. Loh
    Molecular Pharmacology June 2005, 67 (6) 2032-2039; DOI: https://doi.org/10.1124/mol.105.011056
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    Expression of Native α3β4* Neuronal Nicotinic Receptors: Binding and Functional Studies Investigating Turnover of Surface and Intracellular Receptor Populations
    R. Benjamin Free, Susan B. McKay, Paul D. Gottlieb, R. Thomas Boyd and Dennis B. McKay
    Molecular Pharmacology June 2005, 67 (6) 2040-2048; DOI: https://doi.org/10.1124/mol.104.009282
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    Cell Cycle Signaling by Endothelin-1 Requires Src Nonreceptor Protein Tyrosine Kinase
    Rangnath Mishra, Yuan Wang and Michael S. Simonson
    Molecular Pharmacology June 2005, 67 (6) 2049-2056; DOI: https://doi.org/10.1124/mol.104.010546
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    Activating Protein 1-Mediated Cyclooxygenase-2 Expression Is Independent of N-Terminal Phosphorylation of c-Jun
    Lei-Chin Chen, Ben-Kuen Chen and Wen-Chang Chang
    Molecular Pharmacology June 2005, 67 (6) 2057-2069; DOI: https://doi.org/10.1124/mol.104.010900
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    Identification and Pharmacological Characterization of Prokineticin 2β as a Selective Ligand for Prokineticin Receptor 1
    Jingcai Chen, Chester Kuei, Steven Sutton, Sandy Wilson, Jingxue Yu, Fredrik Kamme, Curt Mazur, Timothy Lovenberg and Changlu Liu
    Molecular Pharmacology June 2005, 67 (6) 2070-2076; DOI: https://doi.org/10.1124/mol.105.011619
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    Evidence for Biphasic Effects of Protein Kinase C on Serotonin Transporter Function, Endocytosis, and Phosphorylation
    Lankupalle D. Jayanthi, Devadoss J. Samuvel, Randy D. Blakely and Sammanda Ramamoorthy
    Molecular Pharmacology June 2005, 67 (6) 2077-2087; DOI: https://doi.org/10.1124/mol.104.009555
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    Transcriptional Regulation of the Human Hepatic CYP3A4: Identification of a New Distal Enhancer Region Responsive to CCAAT/Enhancer-Binding Protein β Isoforms (Liver Activating Protein and Liver Inhibitory Protein)
    Celia P. Martínez-Jiménez, M. José Gómez-Lechón, José V. Castell and Ramiro Jover
    Molecular Pharmacology June 2005, 67 (6) 2088-2101; DOI: https://doi.org/10.1124/mol.104.008169
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    Differential Effects of Gqα, G14α, and G15α on Vascular Smooth Muscle Cell Survival and Gene Expression Profiles
    Richard D. Peavy, Katherine B. Hubbard, Anthony Lau, R. Brett Fields, Kaiming Xu, C. Justin Lee, Terri T. Lee, Kimberly Gernert, T. J. Murphy and John R. Hepler
    Molecular Pharmacology June 2005, 67 (6) 2102-2114; DOI: https://doi.org/10.1124/mol.104.007799
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    Neuron-Restrictive Silencer Factor Regulates the N-Methyl-d-aspartate Receptor 2B Subunit Gene in Basal and Ethanol-Induced Gene Expression in Fetal Cortical Neurons
    Mei Qiang, C. S. Sheela Rani and Maharaj K. Ticku
    Molecular Pharmacology June 2005, 67 (6) 2115-2125; DOI: https://doi.org/10.1124/mol.104.010751
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    Potential Role of cAMP Response Element-Binding Protein in Ethanol-Induced N-Methyl-d-aspartate Receptor 2B Subunit Gene Transcription in Fetal Mouse Cortical Cells
    C. S. Sheela Rani, Mei Qiang and Maharaj K. Ticku
    Molecular Pharmacology June 2005, 67 (6) 2126-2136; DOI: https://doi.org/10.1124/mol.104.007872
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    Expression, Pharmacological Profile, and Functional Coupling of A2B Receptors in a Recombinant System and in Peripheral Blood Cells Using a Novel Selective Antagonist Radioligand, [3H]MRE 2029-F20
    Stefania Gessi, Katia Varani, Stefania Merighi, Elena Cattabriga, Cecilia Pancaldi, Youri Szabadkai, Rosario Rizzuto, Karl-Norbert Klotz, Edward Leung, Stephen Mac Lennan, Pier Giovanni Baraldi and Pier Andrea Borea
    Molecular Pharmacology June 2005, 67 (6) 2137-2147; DOI: https://doi.org/10.1124/mol.104.009225
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    Tristetraprolin Regulates the Expression of the Human Inducible Nitric-Oxide Synthase Gene
    Marcel Fechir, Katrin Linker, Andrea Pautz, Thomas Hubrich, Ulrich Förstermann, Fernando Rodriguez-Pascual and Hartmut Kleinert
    Molecular Pharmacology June 2005, 67 (6) 2148-2161; DOI: https://doi.org/10.1124/mol.104.008763
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    Somatostatin Increases Phospholipase D Activity and Phosphatidylinositol 4,5-bisphosphate Synthesis in Clonal β Cells HIT-T15
    Henrique Cheng, Justin A. Grodnitzky, Sirintorn Yibchok-anun, Jing Ding and Walter H. Hsu
    Molecular Pharmacology June 2005, 67 (6) 2162-2172; DOI: https://doi.org/10.1124/mol.104.010470
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    Opioid Receptor Homo- and Heterodimerization in Living Cells by Quantitative Bioluminescence Resonance Energy Transfer
    Danxin Wang, Xiaochun Sun, Laura M. Bohn and Wolfgang Sadée
    Molecular Pharmacology June 2005, 67 (6) 2173-2184; DOI: https://doi.org/10.1124/mol.104.010272

Errata

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    Correction to “From Plants to Man: The GPCR `Tree of Life'”
    Molecular Pharmacology June 2005, 67 (6) 2185; DOI: https://doi.org/10.1124/mol.67.6.2185
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    Correction to “Vacuolar Degradation of Rat Liver CYP2B1 in Saccharomyces cerevisiae: Further Validation of the Yeast Model and Structural Implications for the Degradation of Mammalian Endoplasmic Reticulum P450 Proteins”
    Molecular Pharmacology June 2005, 67 (6) 2186; DOI: https://doi.org/10.1124/mol.67.6.2186
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Molecular Pharmacology: 67 (6)
Molecular Pharmacology
Vol. 67, Issue 6
1 Jun 2005
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