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Research ArticleArticle

Farnesyltransferase Inhibitor BMS-214662 Induces Apoptosis in Myeloma Cells through PUMA Up-Regulation, Bax and Bak Activation, and Mcl-1 Elimination

María Gómez-Benito, Isabel Marzo, Alberto Anel and Javier Naval
Molecular Pharmacology June 2005, 67 (6) 1991-1998; DOI: https://doi.org/10.1124/mol.104.007021

Article Information

vol. 67 no. 6 1991-1998
DOI 
https://doi.org/10.1124/mol.104.007021
PubMed 
15738311
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received September 17, 2004
  • Accepted February 28, 2005
  • Published online May 16, 2005.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. María Gómez-Benito,
  2. Isabel Marzo,
  3. Alberto Anel and
  4. Javier Naval
  1. Departamento de Bioquimica y Biologia Molecular y Celular, Facultad de Ciencias, Universidad de Zaragoza, Zaragoza, Spain
  1. Address correspondence to:
    Dr. Isabel Marzo, Departamento de Bioquimica y Biologia Molecular y Celular, Facultad de Ciencias, Universidad de Zaragoza; 50009 Zaragoza, Spain. E-mail: imarzo{at}unizar.es
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Research ArticleArticle

Farnesyltransferase Inhibitor BMS-214662 Induces Apoptosis in Myeloma Cells through PUMA Up-Regulation, Bax and Bak Activation, and Mcl-1 Elimination

María Gómez-Benito, Isabel Marzo, Alberto Anel and Javier Naval
Molecular Pharmacology June 1, 2005, 67 (6) 1991-1998; DOI: https://doi.org/10.1124/mol.104.007021
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