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Molecular Pharmacology

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Table of Contents

August 01, 2005; Volume 68,Issue 2

Minireview

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    Molecular Pharmacology of the Interaction of Anthracyclines with Iron
    X. Xu, H. L. Persson and D. R. Richardson
    Molecular Pharmacology August 2005, 68 (2) 261-271; DOI: https://doi.org/10.1124/mol.105.013383

Perspectives

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    How the Monoamine Transporter Garden Grows
    Arnold E. Ruoho
    Molecular Pharmacology August 2005, 68 (2) 272-274; DOI: https://doi.org/10.1124/mol.105.014951
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    Double Feature at the Signalplex
    Kim A. Neve
    Molecular Pharmacology August 2005, 68 (2) 275-278; DOI: https://doi.org/10.1124/mol.105.015263

Accelerated Communication

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    A Major Species of Mouse μ-opioid Receptor mRNA and Its Promoter-Dependent Functional Polyadenylation Signal
    Qifang Wu, Cheol Kyu Hwang, Shiyi Yao, Ping-Yee Law, Horace H. Loh and Li-Na Wei
    Molecular Pharmacology August 2005, 68 (2) 279-285; DOI: https://doi.org/10.1124/mol.105.012567

Articles

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    Novel Mechanism of Inhibition of Nuclear Factor-κB DNA-Binding Activity by Diterpenoids Isolated from Isodon rubescens
    Chung-Hang Leung, Susan P. Grill, Wing Lam, Quan-Bin Han, Han-Dong Sun and Yung-Chi Cheng
    Molecular Pharmacology August 2005, 68 (2) 286-297; DOI: https://doi.org/10.1124/mol.105.012765
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    Molecular Basis of Inward Rectification: Structural Features of the Blocker Defined by Extended Polyamine Analogs
    G. Loussouarn, L. J. Marton and C. G. Nichols
    Molecular Pharmacology August 2005, 68 (2) 298-304; DOI: https://doi.org/10.1124/mol.105.012377
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    A Single Residue in the S6 Transmembrane Domain Governs the Differential Flecainide Sensitivity of Voltage-Gated Potassium Channels
    Daniel Herrera, Aida Mamarbachi, Manuel Simoes, Lucie Parent, Rémy Sauvé, Zhiguo Wang and Stanley Nattel
    Molecular Pharmacology August 2005, 68 (2) 305-316; DOI: https://doi.org/10.1124/mol.104.009506
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    Cyclooxygenase-2 Inhibitors Decrease Vascular Endothelial Growth Factor Expression in Colon Cancer Cells by Enhanced Degradation of Sp1 and Sp4 Proteins
    Maen Abdelrahim and Stephen Safe
    Molecular Pharmacology August 2005, 68 (2) 317-329; DOI: https://doi.org/10.1124/mol.105.011825
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    The Coordination of Prostaglandin E2 Production by Sphingosine-1-phosphate and Ceramide-1-phosphate
    Benjamin J. Pettus, Kazuyuki Kitatani, Charles E. Chalfant, Tarek A. Taha, Toshihiko Kawamori, Jacek Bielawski, Lina M. Obeid and Yusuf A. Hannun
    Molecular Pharmacology August 2005, 68 (2) 330-335; DOI: https://doi.org/10.1124/mol.104.008722
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    Arsenite-Induced Aryl Hydrocarbon Receptor Nuclear Translocation Results in Additive Induction of Phase I Genes and Synergistic Induction of Phase II Genes
    Simone Kann, Ming-ya Huang, Cameron Estes, John F. Reichard, Maureen A. Sartor, Ying Xia and Alvaro Puga
    Molecular Pharmacology August 2005, 68 (2) 336-346; DOI: https://doi.org/10.1124/mol.105.011841
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    Single Mutations at Asn295 and Leu305 in the Cytoplasmic Half of Transmembrane α-Helix Domain 7 of the AT1 Receptor Induce Promiscuous Agonist Specificity for Angiotensin II Fragments: A Pseudo-Constitutive Activity
    Ying-Hong Feng, Lingyin Zhou, Rongde Qiu and Robin Zeng
    Molecular Pharmacology August 2005, 68 (2) 347-355; DOI: https://doi.org/10.1124/mol.105.011601
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    Agonist-Induced Interactions between Angiotensin AT1 and Epidermal Growth Factor Receptors
    J. Alberto Olivares-Reyes, Bukhtiar H. Shah, Judith Hernández-Aranda, Agustín García-Caballero, M. Parvaiz Farshori, J. Adolfo García-Sáinz and Kevin J. Catt
    Molecular Pharmacology August 2005, 68 (2) 356-364; DOI: https://doi.org/10.1124/mol.104.010637
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    Spatial Orientation of the Antagonist Granisetron in the Ligand-Binding Site of the 5-HT3 Receptor
    Dong Yan and Michael M. White
    Molecular Pharmacology August 2005, 68 (2) 365-371; DOI: https://doi.org/10.1124/mol.105.011957
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    Chemotherapy Compounds in Cervical Cancer Cells Primed by Reconstitution of p53 Function after Short Interfering RNA-Mediated Degradation of Human Papillomavirus 18 E6 mRNA: Opposite Effect of siRNA in Combination with Different Drugs
    Riku Koivusalo, Eberhard Krausz, Hans Helenius and Sakari Hietanen
    Molecular Pharmacology August 2005, 68 (2) 372-382; DOI: https://doi.org/10.1124/mol.105.011189
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    Discovery of Novel Flavin-Containing Monooxygenase 3 (FMO3) Single Nucleotide Polymorphisms and Functional Analysis of Upstream Haplotype Variants
    Sevasti B. Koukouritaki, Mark T. Poch, Erwin T. Cabacungan, D. Gail McCarver and Ronald N. Hines
    Molecular Pharmacology August 2005, 68 (2) 383-392; DOI: https://doi.org/10.1124/mol.105.012062
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    Identification of Indole Derivatives Exclusively Interfering with a G Protein-Independent Signaling Pathway of the Prostaglandin D2 Receptor CRTH2
    Jesper Mosolff Mathiesen, Trond Ulven, Lene Martini, Lars Ole Gerlach, Akos Heinemann and Evi Kostenis
    Molecular Pharmacology August 2005, 68 (2) 393-402; DOI: https://doi.org/10.1124/mol.104.010520
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    A Pregnane X Receptor Agonist with Unique Species-Dependent Stereoselectivity and Its Implications in Drug Development
    Ying Mu, Corey R. J. Stephenson, Christopher Kendall, Simrat P. S. Saini, David Toma, Songrong Ren, Hongbo Cai, Stephen C. Strom, Billy W. Day, Peter Wipf and Wen Xie
    Molecular Pharmacology August 2005, 68 (2) 403-413; DOI: https://doi.org/10.1124/mol.105.013292
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    Down-Regulation of Na+/Ca2+ Exchanger by Fluvastatin in Rat Cardiomyoblast H9c2 Cells: Involvement of RhoB in Na+/Ca2+ Exchanger mRNA Stability
    Sachiko Maeda, Isao Matsuoka, Takahiro Iwamoto, Hitoshi Kurose and Junko Kimura
    Molecular Pharmacology August 2005, 68 (2) 414-420; DOI: https://doi.org/10.1124/mol.104.000786
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    cAMP and Extracellular Signal-Regulated Kinase Signaling in Response to d-Amphetamine and Methylphenidate in the Prefrontal Cortex in Vivo: Role of β1-Adrenoceptors
    Vincent Pascoli, Emmanuel Valjent, Anne-Gaëlle Corbillé, Jean-Christophe Corvol, Jean-Pol Tassin, Jean-Antoine Girault and Denis Hervé
    Molecular Pharmacology August 2005, 68 (2) 421-429; DOI: https://doi.org/10.1124/mol.105.011809
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    Expression Profiling of ABC Transporters in a Drug-Resistant Breast Cancer Cell Line Using AmpArray
    Yang Liu, Hui Peng and Jian-Ting Zhang
    Molecular Pharmacology August 2005, 68 (2) 430-438; DOI: https://doi.org/10.1124/mol.105.011015
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    Integrin Engagement Increases Histone H3 Acetylation and Reduces Histone H1 Association with DNA in Murine Lung Endothelial Cells
    Jane L. Rose, Hong Huang, Scott F. Wray and Dale G. Hoyt
    Molecular Pharmacology August 2005, 68 (2) 439-446; DOI: https://doi.org/10.1124/mol.104.010876
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    Orphanin FQ/Nociceptin Potentiates [D-Ala2,N-Me-Phe4,Gly5-ol]-Enkephalin–Induced μ-Opioid Receptor Phosphorylation
    Hatice Z. Ozsoy, Deepak R. Thakker and Kelly M. Standifer
    Molecular Pharmacology August 2005, 68 (2) 447-456; DOI: https://doi.org/10.1124/mol.105.011536
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    Single Nucleotide Polymorphisms in the Human Norepinephrine Transporter Gene Affect Expression, Trafficking, Antidepressant Interaction, and Protein Kinase C Regulation
    Maureen K. Hahn, Michelle S. Mazei-Robison and Randy D. Blakely
    Molecular Pharmacology August 2005, 68 (2) 457-466; DOI: https://doi.org/10.1124/mol.105.011270
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    Long-Term Morphine Treatment Enhances Proteasome-Dependent Degradation of Gβ in Human Neuroblastoma SH-SY5Y Cells: Correlation with Onset of Adenylate Cyclase Sensitization
    Lionel Moulédous, Jérémie Neasta, Sandrine Uttenweiler-Joseph, Alexandre Stella, Mariette Matondo, Maïthé Corbani, Bernard Monsarrat and Jean-Claude Meunier
    Molecular Pharmacology August 2005, 68 (2) 467-476; DOI: https://doi.org/10.1124/mol.105.013391
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    Characterization of a Human Carcinoma Cell Line Selected for Resistance to the Farnesyl Transferase Inhibitor 4-(2-(4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo-(5,6)-cyclohepta(1,2-b)-pyridin-11(R)-yl)-1-piperidinyl)-2-oxo-ethyl)-1-piperidinecarboxamide (SCH66336)
    Laura M. Bruzek, Jenny N. Poynter, Scott H. Kaufmann and Alex A. Adjei
    Molecular Pharmacology August 2005, 68 (2) 477-486; DOI: https://doi.org/10.1124/mol.104.010074
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    Mutations Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Affect Allosteric Ca2+ Activation of the α4β2 Nicotinic Acetylcholine Receptor
    Nivalda O. Rodrigues-Pinguet, Thierry J. Pinguet, Antonio Figl, Henry A. Lester and Bruce N. Cohen
    Molecular Pharmacology August 2005, 68 (2) 487-501; DOI: https://doi.org/10.1124/mol.105.011155
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    Kahalalide F Induces Necrosis-Like Cell Death that Involves Depletion of ErbB3 and Inhibition of Akt Signaling
    Maarten L. Janmaat, José A. Rodriguez, José Jimeno, Frank A. E. Kruyt and Giuseppe Giaccone
    Molecular Pharmacology August 2005, 68 (2) 502-510; DOI: https://doi.org/10.1124/mol.105.011361
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    Coactivation of the Human Vitamin D Receptor by the Peroxisome Proliferator-Activated Receptor γ Coactivator-1 α
    Rajesh S. Savkur, Kelli S. Bramlett, Keith R. Stayrook, Sunil Nagpal and Thomas P. Burris
    Molecular Pharmacology August 2005, 68 (2) 511-517; DOI: https://doi.org/10.1124/mol.105.012708
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    Conservation of Functional and Pharmacological Properties in the Distantly Related Temperature Sensors TRPV1 and TRPM8
    Annette Weil, Stephen E. Moore, Nicola J. Waite, Andrew Randall and Martin J. Gunthorpe
    Molecular Pharmacology August 2005, 68 (2) 518-527; DOI: https://doi.org/10.1124/mol.105.012146
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    N-Methyl-d-aspartate Attenuates CXCR2-Mediated Neuroprotection through Enhancing the Receptor Phosphorylation and Blocking the Receptor Recycling
    Qingwei Luo, Yun Ding, Kurt Watson, Jingwu Zhang and Guo-Huang Fan
    Molecular Pharmacology August 2005, 68 (2) 528-537; DOI: https://doi.org/10.1124/mol.105.011197
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    Diketo Hexenoic Acid Derivatives Are Novel Selective Non-Nucleoside Inhibitors of Mammalian Terminal Deoxynucleotidyl Transferases, with Potent Cytotoxic Effect against Leukemic Cells
    Giada A. Locatelli, Roberto Di Santo, Emmanuele Crespan, Roberta Costi, Alessandra Roux, Ulrich Hübscher, Igor Shevelev, Giuseppina Blanca, Giuseppe Villani, Silvio Spadari and Giovanni Maga
    Molecular Pharmacology August 2005, 68 (2) 538-550; DOI: https://doi.org/10.1124/mol.105.013326
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    The Methyl Transferase PRMT1 Functions as Co-Activator of Farnesoid X Receptor (FXR)/9-cis Retinoid X Receptor and Regulates Transcription of FXR Responsive Genes
    Giovanni Rizzo, Barbara Renga, Elisabetta Antonelli, Daniela Passeri, Roberto Pellicciari and Stefano Fiorucci
    Molecular Pharmacology August 2005, 68 (2) 551-558; DOI: https://doi.org/10.1124/mol.105.012104
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Molecular Pharmacology: 68 (2)
Molecular Pharmacology
Vol. 68, Issue 2
1 Aug 2005
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  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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