Table of Contents

Articles

• You have access

  Novel Mechanism of Inhibition of Nuclear Factor-κB DNA-Binding Activity by Diterpenoids Isolated from Isodon rubescens

  Chung-Hang Leung, Susan P. Grill, Wing Lam, Quan-Bin Han, Han-Dong Sun and Yung-Chi Cheng

  Molecular Pharmacology August 2005, 68 (2) 286-297; DOI: https://doi.org/10.1124/mol.105.012765
• You have access

  Molecular Basis of Inward Rectification: Structural Features of the Blocker Defined by Extended Polyamine Analogs

  G. Loussouarn, L. J. Marton and C. G. Nichols

  Molecular Pharmacology August 2005, 68 (2) 298-304; DOI: https://doi.org/10.1124/mol.105.012377
• You have access

  A Single Residue in the S6 Transmembrane Domain Governs the Differential Flecainide Sensitivity of Voltage-Gated Potassium Channels

  Daniel Herrera, Aida Mamarbachi, Manuel Simoes, Lucie Parent, Rémy Sauvé, Zhiguo Wang and Stanley Nattel

  Molecular Pharmacology August 2005, 68 (2) 305-316; DOI: https://doi.org/10.1124/mol.104.009506
• You have access

  Cyclooxygenase-2 Inhibitors Decrease Vascular Endothelial Growth Factor Expression in Colon Cancer Cells by Enhanced Degradation of Sp1 and Sp4 Proteins

  Maen Abdelrahim and Stephen Safe

  Molecular Pharmacology August 2005, 68 (2) 317-329; DOI: https://doi.org/10.1124/mol.105.011825
• You have access

  The Coordination of Prostaglandin E₂ Production by Sphingosine-1-phosphate and Ceramide-1-phosphate

  Benjamin J. Pettus, Kazuyuki Kitatani, Charles E. Chalfant, Tarek A. Taha, Toshihiko Kawamori, Jacek Bielawski, Lina M. Obeid and Yusuf A. Hannun

  Molecular Pharmacology August 2005, 68 (2) 330-335; DOI: https://doi.org/10.1124/mol.104.008722
• You have access

  Arsenite-Induced Aryl Hydrocarbon Receptor Nuclear Translocation Results in Additive Induction of Phase I Genes and Synergistic Induction of Phase II Genes

  Simone Kann, Ming-ya Huang, Cameron Estes, John F. Reichard, Maureen A. Sartor, Ying Xia and Alvaro Puga

  Molecular Pharmacology August 2005, 68 (2) 336-346; DOI: https://doi.org/10.1124/mol.105.011841
• You have access

  Single Mutations at Asn²⁹⁵ and Leu³⁰⁵ in the Cytoplasmic Half of Transmembrane α-Helix Domain 7 of the AT₁ Receptor Induce Promiscuous Agonist Specificity for Angiotensin II Fragments: A Pseudo-Constitutive Activity

  Ying-Hong Feng, Lingyin Zhou, Rongde Qiu and Robin Zeng

  Molecular Pharmacology August 2005, 68 (2) 347-355; DOI: https://doi.org/10.1124/mol.105.011601
• You have access

  Agonist-Induced Interactions between Angiotensin AT₁ and Epidermal Growth Factor Receptors

  J. Alberto Olivares-Reyes, Bukhtiar H. Shah, Judith Hernández-Aranda, Agustín García-Caballero, M. Parvaiz Farshori, J. Adolfo García-Sáinz and Kevin J. Catt

  Molecular Pharmacology August 2005, 68 (2) 356-364; DOI: https://doi.org/10.1124/mol.104.010637
• You have access

  Spatial Orientation of the Antagonist Granisetron in the Ligand-Binding Site of the 5-HT₃ Receptor

  Dong Yan and Michael M. White

  Molecular Pharmacology August 2005, 68 (2) 365-371; DOI: https://doi.org/10.1124/mol.105.011957
• You have access

  Chemotherapy Compounds in Cervical Cancer Cells Primed by Reconstitution of p53 Function after Short Interfering RNA-Mediated Degradation of Human Papillomavirus 18 E6 mRNA: Opposite Effect of siRNA in Combination with Different Drugs

  Riku Koivusalo, Eberhard Krausz, Hans Helenius and Sakari Hietanen

  Molecular Pharmacology August 2005, 68 (2) 372-382; DOI: https://doi.org/10.1124/mol.105.011189
• You have access

  Discovery of Novel Flavin-Containing Monooxygenase 3 (FMO3) Single Nucleotide Polymorphisms and Functional Analysis of Upstream Haplotype Variants

  Sevasti B. Koukouritaki, Mark T. Poch, Erwin T. Cabacungan, D. Gail McCarver and Ronald N. Hines

  Molecular Pharmacology August 2005, 68 (2) 383-392; DOI: https://doi.org/10.1124/mol.105.012062
• You have access

  Identification of Indole Derivatives Exclusively Interfering with a G Protein-Independent Signaling Pathway of the Prostaglandin D2 Receptor CRTH2

  Jesper Mosolff Mathiesen, Trond Ulven, Lene Martini, Lars Ole Gerlach, Akos Heinemann and Evi Kostenis

  Molecular Pharmacology August 2005, 68 (2) 393-402; DOI: https://doi.org/10.1124/mol.104.010520
• You have access

  A Pregnane X Receptor Agonist with Unique Species-Dependent Stereoselectivity and Its Implications in Drug Development

  Ying Mu, Corey R. J. Stephenson, Christopher Kendall, Simrat P. S. Saini, David Toma, Songrong Ren, Hongbo Cai, Stephen C. Strom, Billy W. Day, Peter Wipf and Wen Xie

  Molecular Pharmacology August 2005, 68 (2) 403-413; DOI: https://doi.org/10.1124/mol.105.013292
• You have access

  Down-Regulation of Na⁺/Ca²⁺ Exchanger by Fluvastatin in Rat Cardiomyoblast H9c2 Cells: Involvement of RhoB in Na⁺/Ca²⁺ Exchanger mRNA Stability

  Sachiko Maeda, Isao Matsuoka, Takahiro Iwamoto, Hitoshi Kurose and Junko Kimura

  Molecular Pharmacology August 2005, 68 (2) 414-420; DOI: https://doi.org/10.1124/mol.104.000786
• You have access

  cAMP and Extracellular Signal-Regulated Kinase Signaling in Response to d-Amphetamine and Methylphenidate in the Prefrontal Cortex in Vivo: Role of β1-Adrenoceptors

  Vincent Pascoli, Emmanuel Valjent, Anne-Gaëlle Corbillé, Jean-Christophe Corvol, Jean-Pol Tassin, Jean-Antoine Girault and Denis Hervé

  Molecular Pharmacology August 2005, 68 (2) 421-429; DOI: https://doi.org/10.1124/mol.105.011809
• You have access

  Expression Profiling of ABC Transporters in a Drug-Resistant Breast Cancer Cell Line Using AmpArray

  Yang Liu, Hui Peng and Jian-Ting Zhang

  Molecular Pharmacology August 2005, 68 (2) 430-438; DOI: https://doi.org/10.1124/mol.105.011015
• You have access

  Integrin Engagement Increases Histone H3 Acetylation and Reduces Histone H1 Association with DNA in Murine Lung Endothelial Cells

  Jane L. Rose, Hong Huang, Scott F. Wray and Dale G. Hoyt

  Molecular Pharmacology August 2005, 68 (2) 439-446; DOI: https://doi.org/10.1124/mol.104.010876
• You have access

  Orphanin FQ/Nociceptin Potentiates [D-Ala²,N-Me-Phe⁴,Gly⁵-ol]-Enkephalin–Induced μ-Opioid Receptor Phosphorylation

  Hatice Z. Ozsoy, Deepak R. Thakker and Kelly M. Standifer

  Molecular Pharmacology August 2005, 68 (2) 447-456; DOI: https://doi.org/10.1124/mol.105.011536
• You have access

  Single Nucleotide Polymorphisms in the Human Norepinephrine Transporter Gene Affect Expression, Trafficking, Antidepressant Interaction, and Protein Kinase C Regulation

  Maureen K. Hahn, Michelle S. Mazei-Robison and Randy D. Blakely

  Molecular Pharmacology August 2005, 68 (2) 457-466; DOI: https://doi.org/10.1124/mol.105.011270
• You have access

  Long-Term Morphine Treatment Enhances Proteasome-Dependent Degradation of Gβ in Human Neuroblastoma SH-SY5Y Cells: Correlation with Onset of Adenylate Cyclase Sensitization

  Lionel Moulédous, Jérémie Neasta, Sandrine Uttenweiler-Joseph, Alexandre Stella, Mariette Matondo, Maïthé Corbani, Bernard Monsarrat and Jean-Claude Meunier

  Molecular Pharmacology August 2005, 68 (2) 467-476; DOI: https://doi.org/10.1124/mol.105.013391
• You have access

  Characterization of a Human Carcinoma Cell Line Selected for Resistance to the Farnesyl Transferase Inhibitor 4-(2-(4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo-(5,6)-cyclohepta(1,2-b)-pyridin-11(R)-yl)-1-piperidinyl)-2-oxo-ethyl)-1-piperidinecarboxamide (SCH66336)

  Laura M. Bruzek, Jenny N. Poynter, Scott H. Kaufmann and Alex A. Adjei

  Molecular Pharmacology August 2005, 68 (2) 477-486; DOI: https://doi.org/10.1124/mol.104.010074
• You have access

  Mutations Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Affect Allosteric Ca²⁺ Activation of the α4β2 Nicotinic Acetylcholine Receptor

  Nivalda O. Rodrigues-Pinguet, Thierry J. Pinguet, Antonio Figl, Henry A. Lester and Bruce N. Cohen

  Molecular Pharmacology August 2005, 68 (2) 487-501; DOI: https://doi.org/10.1124/mol.105.011155
• You have access

  Kahalalide F Induces Necrosis-Like Cell Death that Involves Depletion of ErbB3 and Inhibition of Akt Signaling

  Maarten L. Janmaat, José A. Rodriguez, José Jimeno, Frank A. E. Kruyt and Giuseppe Giaccone

  Molecular Pharmacology August 2005, 68 (2) 502-510; DOI: https://doi.org/10.1124/mol.105.011361
• You have access

  Coactivation of the Human Vitamin D Receptor by the Peroxisome Proliferator-Activated Receptor γ Coactivator-1 α

  Rajesh S. Savkur, Kelli S. Bramlett, Keith R. Stayrook, Sunil Nagpal and Thomas P. Burris

  Molecular Pharmacology August 2005, 68 (2) 511-517; DOI: https://doi.org/10.1124/mol.105.012708
• You have access

  Conservation of Functional and Pharmacological Properties in the Distantly Related Temperature Sensors TRPV1 and TRPM8

  Annette Weil, Stephen E. Moore, Nicola J. Waite, Andrew Randall and Martin J. Gunthorpe

  Molecular Pharmacology August 2005, 68 (2) 518-527; DOI: https://doi.org/10.1124/mol.105.012146
• You have access

  N-Methyl-d-aspartate Attenuates CXCR2-Mediated Neuroprotection through Enhancing the Receptor Phosphorylation and Blocking the Receptor Recycling

  Qingwei Luo, Yun Ding, Kurt Watson, Jingwu Zhang and Guo-Huang Fan

  Molecular Pharmacology August 2005, 68 (2) 528-537; DOI: https://doi.org/10.1124/mol.105.011197
• You have access

  Diketo Hexenoic Acid Derivatives Are Novel Selective Non-Nucleoside Inhibitors of Mammalian Terminal Deoxynucleotidyl Transferases, with Potent Cytotoxic Effect against Leukemic Cells

  Giada A. Locatelli, Roberto Di Santo, Emmanuele Crespan, Roberta Costi, Alessandra Roux, Ulrich Hübscher, Igor Shevelev, Giuseppina Blanca, Giuseppe Villani, Silvio Spadari and Giovanni Maga

  Molecular Pharmacology August 2005, 68 (2) 538-550; DOI: https://doi.org/10.1124/mol.105.013326
• You have access

  The Methyl Transferase PRMT1 Functions as Co-Activator of Farnesoid X Receptor (FXR)/9-cis Retinoid X Receptor and Regulates Transcription of FXR Responsive Genes

  Giovanni Rizzo, Barbara Renga, Elisabetta Antonelli, Daniela Passeri, Roberto Pellicciari and Stefano Fiorucci

  Molecular Pharmacology August 2005, 68 (2) 551-558; DOI: https://doi.org/10.1124/mol.105.012104