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Molecular Pharmacology

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Table of Contents

September 01, 2005; Volume 68,Issue 3

Perspectives

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    Can a GDP-Liganded G-Protein Be Active?
    Thomas Wieland and Martin C. Michel
    Molecular Pharmacology September 2005, 68 (3) 559-562; DOI: https://doi.org/10.1124/mol.105.016071
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    The Long and Short of Vascular Smooth Muscle Phosphodiesterase-4 As a Putative Therapeutic Target
    Miles D. Houslay
    Molecular Pharmacology September 2005, 68 (3) 563-567; DOI: https://doi.org/10.1124/mol.105.015719

Articles

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    D1 and D2 Dopamine Receptors Form Heterooligomers and Cointernalize after Selective Activation of Either Receptor
    Christopher H. So, George Varghese, Kevin J. Curley, Michael M. C. Kong, Mohammed Alijaniaram, Xiaodong Ji, Tuan Nguyen, Brian F. O'Dowd and Susan R. George
    Molecular Pharmacology September 2005, 68 (3) 568-578; DOI: https://doi.org/10.1124/mol.105.012229
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    Heterozygous Deficiency of Manganese Superoxide Dismutase in Mice (Mn-SOD+/-): A Novel Approach to Assess the Role of Oxidative Stress for the Development of Nitrate Tolerance
    Andreas Daiber, Matthias Oelze, Silke Sulyok, Meike Coldewey, Eberhard Schulz, Nicolai Treiber, Ulrich Hink, Alexander Mülsch, Karin Scharffetter-Kochanek and Thomas Münzel
    Molecular Pharmacology September 2005, 68 (3) 579-588; DOI: https://doi.org/10.1124/mol.105.011585
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    Molecular Pharmacology of Adenosine Transport in Trypanosoma brucei: P1/P2 Revisited
    Federico Geiser, Alexandra Lüscher, Harry P. de Koning, Thomas Seebeck and Pascal Mäser
    Molecular Pharmacology September 2005, 68 (3) 589-595; DOI: https://doi.org/10.1124/mol.104.010298
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    Vascular Smooth Muscle Cell Phenotype-Dependent Phosphodiesterase 4D Short Form Expression: Role of Differential Histone Acetylation on cAMP-Regulated Function
    Douglas G. Tilley and Donald H. Maurice
    Molecular Pharmacology September 2005, 68 (3) 596-605; DOI: https://doi.org/10.1124/mol.105.014126
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    Vitamin K3 (Menadione)-Induced Oncosis Associated with Keratin 8 Phosphorylation and Histone H3 Arylation
    Gary K. Scott, Christian Atsriku, Patrick Kaminker, Jason Held, Brad Gibson, Michael A. Baldwin and Christopher C. Benz
    Molecular Pharmacology September 2005, 68 (3) 606-615; DOI: https://doi.org/10.1124/mol.105.013474
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    The Reduced Folate Carrier Gene Is a Novel Selectable Marker for Recombinant Protein Overexpression
    Lilah Rothem, Bluma Berman, Michal Stark, Gerrit Jansen and Yehuda G. Assaraf
    Molecular Pharmacology September 2005, 68 (3) 616-624; DOI: https://doi.org/10.1124/mol.105.013540
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    Down-Regulation of DNA Topoisomerase IIα Leads to Prolonged Cell Cycle Transit in G2 and Early M Phases and Increased Survival to Microtubule-Interacting Agents
    Andrzej Skladanowski, Marie-George Côme, Michal Sabisz, Alexandre E. Escargueil and Annette K. Larsen
    Molecular Pharmacology September 2005, 68 (3) 625-634; DOI: https://doi.org/10.1124/mol.105.013995
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    Apigenin Inhibits Expression of Vascular Endothelial Growth Factor and Angiogenesis in Human Lung Cancer Cells: Implication of Chemoprevention of Lung Cancer
    Ling-Zhi Liu, Jing Fang, Qiong Zhou, Xiaowen Hu, Xianglin Shi and Bing-Hua Jiang
    Molecular Pharmacology September 2005, 68 (3) 635-643; DOI: https://doi.org/10.1124/mol.105.011254
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    CYP2C9 Genotype-Dependent Effects on in Vitro Drug-Drug Interactions: Switching of Benzbromarone Effect from Inhibition to Activation in the CYP2C9.3 Variant
    Matthew A. Hummel, Charles W. Locuson, Peter M. Gannett, Dan A. Rock, Carrie M. Mosher, Allan E. Rettie and Timothy S. Tracy
    Molecular Pharmacology September 2005, 68 (3) 644-651; DOI: https://doi.org/10.1124/mol.105.013763
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    The Role of Thr139 in the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Sensitivity to (+)-Calanolide A
    Joeri Auwerx, Fátima Rodríguez-Barrios, Francesca Ceccherini-Silberstein, Ana San-Félix, Sonsoles Velázquez, Erik De Clercq, María-José Camarasa, Carlo-Federico Perno, Federico Gago and Jan Balzarini
    Molecular Pharmacology September 2005, 68 (3) 652-659; DOI: https://doi.org/10.1124/mol.105.012351
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    Enhanced CCAAT/Enhancer-Binding Protein β-Liver-Enriched Inhibitory Protein Production by Oltipraz, Which Accompanies CUG Repeat-Binding Protein-1 (CUGBP1) RNA-Binding Protein Activation, Leads to Inhibition of Preadipocyte Differentiation
    Eun Ju Bae and Sang Geon Kim
    Molecular Pharmacology September 2005, 68 (3) 660-669; DOI: https://doi.org/10.1124/mol.105.012997
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    Thromboxane A2 Promotes Interleukin-6 Biosynthesis Mediated by an Activation of Cyclic AMP-Response Element-Binding Protein in 1321N1 Human Astrocytoma Cells
    Yutaro Obara, Hitoshi Kurose and Norimichi Nakahata
    Molecular Pharmacology September 2005, 68 (3) 670-679; DOI: https://doi.org/10.1124/mol.105.012922
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    Capsaicin Regulates Voltage-Dependent Sodium Channels by Altering Lipid Bilayer Elasticity
    J. A. Lundbæk, P. Birn, S. E. Tape, G. E. S. Toombes, R. Søgaard, Roger E. Koeppe, S. M. Gruner, A. J. Hansen and O. S. Andersen
    Molecular Pharmacology September 2005, 68 (3) 680-689; DOI: https://doi.org/10.1124/mol.105.013573
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    HIV Protease Inhibitors Activate the Unfolded Protein Response in Macrophages: Implication for Atherosclerosis and Cardiovascular Disease
    Huiping Zhou, William M. Pandak, Vijay Lyall, Ramesh Natarajan and Phillip B. Hylemon
    Molecular Pharmacology September 2005, 68 (3) 690-700; DOI: https://doi.org/10.1124/mol.105.012898
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    The Role of Protein Synthesis and Degradation in the Post-Transcriptional Regulation of Rat Multidrug Resistance-Associated Protein 2 (Mrp2, Abcc2)
    B. R. Jones, W. Li, J. Cao, T. A. Hoffman, P. M. Gerk and M. Vore
    Molecular Pharmacology September 2005, 68 (3) 701-710; DOI: https://doi.org/10.1124/mol.105.013144
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    A Rapid New Assay to Detect RNA Editing Reveals Antipsychotic-Induced Changes in Serotonin-2C Transcripts
    Monsheel S. K. Sodhi, David C. Airey, Warren Lambert, Philip W. J. Burnet, Paul J. Harrison and Elaine Sanders-Bush
    Molecular Pharmacology September 2005, 68 (3) 711-719; DOI: https://doi.org/10.1124/mol.105.014134
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    Guanine Nucleotide Exchange-Independent Activation of Gs Protein by β2-Adrenoceptor
    Özlem Uğur, Şükrü Sadik Öner, Paola Molinari, Caterina Ambrosio, Kemal Sayar and H. Ongun Onaran
    Molecular Pharmacology September 2005, 68 (3) 720-728; DOI: https://doi.org/10.1124/mol.104.010306
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    Poly(C) Binding Protein Family Is a Transcription Factor in μ-Opioid Receptor Gene Expression
    Sung-Su Kim, Krishan K. Pandey, Hack Sun Choi, Seong-Youl Kim, Ping-Yee Law, Li-Na Wei and Horace H. Loh
    Molecular Pharmacology September 2005, 68 (3) 729-736; DOI: https://doi.org/10.1124/mol.105.012245
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    Decrease in α3*/α6* Nicotinic Receptors but Not Nicotine-Evoked Dopamine Release in Monkey Brain after Nigrostriatal Damage
    Sarah E. McCallum, Neeraja Parameswaran, Tanuja Bordia, J. Michael McIntosh, Sharon R. Grady and Maryka Quik
    Molecular Pharmacology September 2005, 68 (3) 737-746; DOI: https://doi.org/10.1124/mol.105.012773
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    Human CYP2C8 Is Transcriptionally Regulated by the Nuclear Receptors Constitutive Androstane Receptor, Pregnane X Receptor, Glucocorticoid Receptor, and Hepatic Nuclear Factor 4α
    Stephen S. Ferguson, Yuping Chen, Edward L. LeCluyse, Masahiko Negishi and Joyce A. Goldstein
    Molecular Pharmacology September 2005, 68 (3) 747-757; DOI: https://doi.org/10.1124/mol.105.013169
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    Mechanism of Inhibition of TRPC Cation Channels by 2-Aminoethoxydiphenylborane
    Jean-Philippe Lievremont, Gary S. Bird and James W. Putney
    Molecular Pharmacology September 2005, 68 (3) 758-762; DOI: https://doi.org/10.1124/mol.105.012856
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    Identification of a Novel Selective Peroxisome Proliferator-Activated Receptor α Agonist, 2-Methyl-2-(4-{3-[1-(4-methylbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl]propyl}phenoxy)propanoic Acid (LY518674), That Produces Marked Changes in Serum Lipids and Apolipoprotein A-1 Expression
    Jai Pal Singh, Raymond Kauffman, William Bensch, Guoming Wang, Pam McClelland, James Bean, Chahrzad Montrose, Nathan Mantlo and Asavari Wagle
    Molecular Pharmacology September 2005, 68 (3) 763-768; DOI: https://doi.org/10.1124/mol.105.010991
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    Critical Amino Acid Residues of the Common Allosteric Site on the M2 Muscarinic Acetylcholine Receptor: More Similarities than Differences between the Structurally Divergent Agents Gallamine and Bis(ammonio)alkane-Type Hexamethylene-bis-[dimethyl-(3-phthalimidopropyl)ammonium]dibromide
    Xi-Ping Huang, Stefanie Prilla, Klaus Mohr and John Ellis
    Molecular Pharmacology September 2005, 68 (3) 769-778; DOI: https://doi.org/10.1124/mol.105.014043
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    Pharmacological Telomerase Inhibition Can Sensitize Drug-Resistant and Drug-Sensitive Cells to Chemotherapeutic Treatment
    Ryan J. Ward and Chantal Autexier
    Molecular Pharmacology September 2005, 68 (3) 779-786; DOI: https://doi.org/10.1124/mol.105.011494
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    Novel Plant Substances Acting as β Subunit Isoform-Selective Positive Allosteric Modulators of GABAA Receptors
    Roland Baur, Urs Simmen, Martin Senn, Urs Séquin and Erwin Sigel
    Molecular Pharmacology September 2005, 68 (3) 787-792; DOI: https://doi.org/10.1124/mol.105.011882
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    Norepinephrine Induces Lipolysis in β1/β2/β3-Adrenoceptor Knockout Mice
    Geneviève Tavernier, Maria Jimenez, Jean-Paul Giacobino, Nicolas Hulo, Max Lafontan, Patrick Muzzin and Dominique Langin
    Molecular Pharmacology September 2005, 68 (3) 793-799; DOI: https://doi.org/10.1124/mol.105.014670
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    Involvement of BCRP (ABCG2) in the Biliary Excretion of Pitavastatin
    Masaru Hirano, Kazuya Maeda, Soichiro Matsushima, Yoshitane Nozaki, Hiroyuki Kusuhara and Yuichi Sugiyama
    Molecular Pharmacology September 2005, 68 (3) 800-807; DOI: https://doi.org/10.1124/mol.105.014019
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    CYP3A5 mRNA Degradation by Nonsense-Mediated mRNA Decay
    Florent Busi and Thierry Cresteil
    Molecular Pharmacology September 2005, 68 (3) 808-815; DOI: https://doi.org/10.1124/mol.105.014225
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    Increased Bcl2 Expression by Antisense Oligoribonucleotides Targeting the Adenine-Uridine-Rich Element Motif
    Laura Ghisolfi, Laura Papucci, Annamaria Bevilacqua, Gianfranco Canti, Giuseppe Tataranni, Andrea Lapucci, Nicola Schiavone, Sergio Capaccioli and Angelo Nicolin
    Molecular Pharmacology September 2005, 68 (3) 816-821; DOI: https://doi.org/10.1124/mol.105.014357
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    Effects of Quinine, Quinidine, and Chloroquine on α9α10 Nicotinic Cholinergic Receptors
    Jimena A. Ballestero, Paola V. Plazas, Sebastian Kracun, María E. Gómez-Casati, Julián Taranda, Carla V. Rothlin, Eleonora Katz, Neil S. Millar and A. Belén Elgoyhen
    Molecular Pharmacology September 2005, 68 (3) 822-829; DOI: https://doi.org/10.1124/mol.105.014431
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    Uridine Binding and Transportability Determinants of Human Concentrative Nucleoside Transporters
    Jing Zhang, Kyla M. Smith, Tracey Tackaberry, Frank Visser, Morris J. Robins, Lars P. C. Nielsen, Ireneusz Nowak, Edward Karpinski, Stephen A. Baldwin, James D. Young and Carol E. Cass
    Molecular Pharmacology September 2005, 68 (3) 830-839; DOI: https://doi.org/10.1124/mol.105.012187
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    The Gln4863Ala Mutation within a Putative, Pore-Lining Trans-Membrane Helix of the Cardiac Ryanodine Receptor Channel Alters Both the Kinetics of Ryanoid Interaction and the Subsequent Fractional Conductance
    Kishani M. Ranatunga, Tracy M. Moreno-King, Bhavna Tanna, Ruiwu Wang, S. R. Wayne Chen, Luc Ruest, William Welch and Alan J. Williams
    Molecular Pharmacology September 2005, 68 (3) 840-846; DOI: https://doi.org/10.1124/mol.105.012807
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    Redox Regulation of PTEN by S-Nitrosothiols
    Chang-Xi Yu, Sheng Li and A. Richard Whorton
    Molecular Pharmacology September 2005, 68 (3) 847-854; DOI: https://doi.org/10.1124/mol.104.010504
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    Intracellular K+ Is Required for the Inactivation-Induced High-Affinity Binding of Cisapride to HERG Channels
    Jijin Lin, Jun Guo, Hongying Gang, Peter Wojciechowski, Jeffrey T. Wigle and Shetuan Zhang
    Molecular Pharmacology September 2005, 68 (3) 855-865; DOI: https://doi.org/10.1124/mol.105.012278
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    Identification of Four Novel Exon 5 Splice Variants of the Mouse μ-Opioid Receptor Gene: Functional Consequences of C-Terminal Splicing
    Ying-Xian Pan, Jin Xu, Elizabeth Bolan, Howard S. Moskowitz, Mingming Xu and Gavril W. Pasternak
    Molecular Pharmacology September 2005, 68 (3) 866-875; DOI: https://doi.org/10.1124/mol.105.011858
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    Novel Potent Human Ether-à-Go-Go-Related Gene (hERG) Potassium Channel Enhancers and Their in Vitro Antiarrhythmic Activity
    Jun Zhou, Corinne E. Augelli-Szafran, Jenifer A. Bradley, Xian Chen, Bryan J. Koci, Walter A. Volberg, Zhuoqian Sun and Jason S. Cordes
    Molecular Pharmacology September 2005, 68 (3) 876-884; DOI: https://doi.org/10.1124/mol.105.014035
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    Monitoring the Activation State of the Insulin-Like Growth Factor-1 Receptor and Its Interaction with Protein Tyrosine Phosphatase 1B Using Bioluminescence Resonance Energy Transfer
    Christophe Blanquart, Nicolas Boute, Danièle Lacasa and Tarik Issad
    Molecular Pharmacology September 2005, 68 (3) 885-894; DOI: https://doi.org/10.1124/mol.105.013151
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    Gallotannin Inhibits the Expression of Chemokines and Inflammatory Cytokines in A549 Cells
    Katalin Erdèlyi, Andrea Kiss, Edina Bakondi, Péter Bai, Csaba Szabó, Pál Gergely, Ferenc Erdödi and László Virág
    Molecular Pharmacology September 2005, 68 (3) 895-904; DOI: https://doi.org/10.1124/mol.105.012518
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    Functional Complementation and the Analysis of Opioid Receptor Homodimerization
    Geraldine Pascal and Graeme Milligan
    Molecular Pharmacology September 2005, 68 (3) 905-915; DOI: https://doi.org/10.1124/mol.105.013847

Erratum

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    Correction to “Conservation of Functional and Pharmacological Properties in the Distantly Related Temperature Sensors TRVP1 and TRPM8”
    Molecular Pharmacology September 2005, 68 (3) 916; DOI: https://doi.org/10.1124/mol.68.3.916
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Molecular Pharmacology: 68 (3)
Molecular Pharmacology
Vol. 68, Issue 3
1 Sep 2005
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