Diosgenin Induces Hypoxia-Inducible Factor-1 Activation and Angiogenesis through Estrogen Receptor-Related Phosphatidylinositol 3-kinase/Akt and p38 Mitogen-Activated Protein Kinase Pathways in Osteoblasts

Departments of Primary Care Medicine (M.L.Y.), Obstetrics & Gynecology (M.L.Y.), and Traumatology & Surgery (C.Y.Y.), National Taiwan University Hospital, Taipei, Taiwan; and Institute of Toxicology (J.L.S., C.Y.Y., W.F.C., C.C.C., M.L.K.) and Department of Anatomy and Cell Biology (C.L.C., K.W.T.), College of Medicine, National Taiwan University, Taipei, Taiwan

Address correspondence to:
Min-Liang Kuo, Laboratory of Molecular and Cellular Toxicology, Institute of Toxicology, College of Medicine, National Taiwan University, 1, Section 1, Jen-Ai Road, Taipei, Taiwan. E-mail: toxkml{at}ha.mc.ntu.edu.tw

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