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Research ArticleArticle

Reactive Oxygen Species Elicit Apoptosis by Concurrently Disrupting Topoisomerase II and DNA-Dependent Protein Kinase

Hua-Rui Lu, Hong Zhu, Min Huang, Yi Chen, Yu-Jun Cai, Ze-Hong Miao, Jin-Sheng Zhang and Jian Ding
Molecular Pharmacology October 2005, 68 (4) 983-994; DOI: https://doi.org/10.1124/mol.105.011544
Hua-Rui Lu
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Hong Zhu
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Min Huang
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Yi Chen
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Yu-Jun Cai
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Ze-Hong Miao
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Jin-Sheng Zhang
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Jian Ding
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Article Information

vol. 68 no. 4 983-994
DOI 
https://doi.org/10.1124/mol.105.011544
PubMed 
16024664

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received January 28, 2005
  • Accepted July 15, 2005
  • Published online September 20, 2005.

Article Versions

  • Earlier version (July 15, 2005 - 10:32).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Hua-Rui Lu,
  2. Hong Zhu,
  3. Min Huang,
  4. Yi Chen,
  5. Yu-Jun Cai,
  6. Ze-Hong Miao,
  7. Jin-Sheng Zhang and
  8. Jian Ding
  1. Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, Peoples Republic of China (H.-R.L, H.Z., M.H., Y.C., Y.-J.C., Z.-H.M., J.-S.Z., J.D.); and Graduate School of the Chinese Academy of Sciences, Beijing, Peoples Republic of China (H.-R.L., H.Z., M.H.)
  1. Address correspondence to:
    Dr. Jian Ding, Division of Anti-tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, Peoples Republic of China. E-mail: jding{at}mail.shcnc.ac.cn
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Molecular Pharmacology: 68 (4)
Molecular Pharmacology
Vol. 68, Issue 4
1 Oct 2005
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Research ArticleArticle

Reactive Oxygen Species Elicit Apoptosis by Concurrently Disrupting Topoisomerase II and DNA-Dependent Protein Kinase

Hua-Rui Lu, Hong Zhu, Min Huang, Yi Chen, Yu-Jun Cai, Ze-Hong Miao, Jin-Sheng Zhang and Jian Ding
Molecular Pharmacology October 1, 2005, 68 (4) 983-994; DOI: https://doi.org/10.1124/mol.105.011544

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Research ArticleArticle

Reactive Oxygen Species Elicit Apoptosis by Concurrently Disrupting Topoisomerase II and DNA-Dependent Protein Kinase

Hua-Rui Lu, Hong Zhu, Min Huang, Yi Chen, Yu-Jun Cai, Ze-Hong Miao, Jin-Sheng Zhang and Jian Ding
Molecular Pharmacology October 1, 2005, 68 (4) 983-994; DOI: https://doi.org/10.1124/mol.105.011544
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