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Molecular Pharmacology

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Table of Contents

November 01, 2005; Volume 68,Issue 5

Perspective

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    Live Long and Prosper
    John S. Lazo
    Molecular Pharmacology November 2005, 68 (5) 1193-1195; DOI: https://doi.org/10.1124/mol.105.017723

Articles

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    Stimulation of Endocannabinoid Formation in Brain Slice Cultures through Activation of Group I Metabotropic Glutamate Receptors
    Kwang-Mook Jung, Regina Mangieri, Christopher Stapleton, Janet Kim, Darren Fegley, Matthew Wallace, Ken Mackie and Daniele Piomelli
    Molecular Pharmacology November 2005, 68 (5) 1196-1202; DOI: https://doi.org/10.1124/mol.105.013961
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    15-Deoxy-Δ12,14 Prostaglandin J2 Up-Regulates Krüppel-Like Factor 4 Expression Independently of Peroxisome Proliferator-Activated Receptor γ by Activating the Mitogen-Activated Protein Kinase Kinase/Extracellular Signal-Regulated Kinase Signal Transduction Pathway in HT-29 Colon Cancer Cells
    Zhi Yi Chen and Chi-Chuan Tseng
    Molecular Pharmacology November 2005, 68 (5) 1203-1213; DOI: https://doi.org/10.1124/mol.105.014944
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    Substance P, Neurokinins A and B, and Synthetic Tachykinin Peptides Protect Mesencephalic Dopaminergic Neurons in Culture via an Activity-Dependent Mechanism
    Bénédicte Salthun-Lassalle, Sabine Traver, Etienne C. Hirsch and Patrick P. Michel
    Molecular Pharmacology November 2005, 68 (5) 1214-1224; DOI: https://doi.org/10.1124/mol.105.015453
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    Expression Profiling of Rat Femur Revealed Suppression of Bone Formation Genes by Treatment with Alendronate and Estrogen but Not Raloxifene
    Leah M. Helvering, Riting Liu, Nalini H. Kulkarni, Tao Wei, Peining Chen, Shuguang Huang, Frank Lawrence, David L. Halladay, Rebecca R. Miles, Emily M. Ambrose, Masahiko Sato, Yanfei L. Ma, Charles A. Frolik, Ernst R. Dow, Henry U. Bryant and Jude E. Onyia
    Molecular Pharmacology November 2005, 68 (5) 1225-1238; DOI: https://doi.org/10.1124/mol.105.011478
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    Retinoid X Receptor-α-Dependent Transactivation by a Naturally Occurring Structural Variant of Human Constitutive Androstane Receptor (NR1I3)
    Scott S. Auerbach, Matthew A. Stoner, Shengzhong Su and Curtis J. Omiecinski
    Molecular Pharmacology November 2005, 68 (5) 1239-1253; DOI: https://doi.org/10.1124/mol.105.013417
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    Design of PAP-1, a Selective Small Molecule Kv1.3 Blocker, for the Suppression of Effector Memory T Cells in Autoimmune Diseases
    Alexander Schmitz, Ananthakrishnan Sankaranarayanan, Philippe Azam, Kristina Schmidt-Lassen, Daniel Homerick, Wolfram Hänsel and Heike Wulff
    Molecular Pharmacology November 2005, 68 (5) 1254-1270; DOI: https://doi.org/10.1124/mol.105.015669
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    Characterization of Determinants of Ligand Binding to the Nicotinic Acid Receptor GPR109A (HM74A/PUMA-G)
    Sorin Tunaru, Jens Lättig, Jukka Kero, Gerd Krause and Stefan Offermanns
    Molecular Pharmacology November 2005, 68 (5) 1271-1280; DOI: https://doi.org/10.1124/mol.105.015750
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    A Prodrug of Cysteine, l-2-Oxothiazolidine-4-carboxylic Acid, Regulates Vascular Permeability by Reducing Vascular Endothelial Growth Factor Expression in Asthma
    Kyung Sun Lee, Hee Sun Park, Seoung Ju Park, So Ri Kim, Kyung Hoon Min, Sun Mi Jin, Kwang-Hyun Park, Uh-Hyun Kim, Chan Young Kim and Yong Chul Lee
    Molecular Pharmacology November 2005, 68 (5) 1281-1290; DOI: https://doi.org/10.1124/mol.105.016055
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    Comparative Models of GABAA Receptor Extracellular and Transmembrane Domains: Important Insights in Pharmacology and Function
    Margot Ernst, Stefan Bruckner, Stefan Boresch and Werner Sieghart
    Molecular Pharmacology November 2005, 68 (5) 1291-1300; DOI: https://doi.org/10.1124/mol.105.015982
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    Integration of Virtual Screening with High-Throughput Flow Cytometry to Identify Novel Small Molecule Formylpeptide Receptor Antagonists
    Bruce S. Edwards, Cristian Bologa, Susan M. Young, Konstantin V. Balakin, Eric R. Prossnitz, Nikolay P. Savchuck, Larry A. Sklar and Tudor I. Oprea
    Molecular Pharmacology November 2005, 68 (5) 1301-1310; DOI: https://doi.org/10.1124/mol.105.014068
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    RNA Interference against Human Papillomavirus Oncogenes in Cervical Cancer Cells Results in Increased Sensitivity to Cisplatin
    Lisa N. Putral, Megan J. Bywater, Wenyi Gu, Nicholas A. Saunders, Brian G. Gabrielli, Graham R. Leggatt and Nigel A. J. McMillan
    Molecular Pharmacology November 2005, 68 (5) 1311-1319; DOI: https://doi.org/10.1124/mol.105.014191
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    Src Family Kinase Activity Is Required for Murine Embryonic Stem Cell Growth and Differentiation
    Malcolm A. Meyn, Steven J. Schreiner, Teodora Pene Dumitrescu, Gerard J. Nau and Thomas E. Smithgall
    Molecular Pharmacology November 2005, 68 (5) 1320-1330; DOI: https://doi.org/10.1124/mol.104.010231
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    Roscovitine Triggers Excitotoxicity in Cultured Granule Neurons by Enhancing Glutamate Release
    Edward A. Monaco and Mary Lou Vallano
    Molecular Pharmacology November 2005, 68 (5) 1331-1342; DOI: https://doi.org/10.1124/mol.105.012732
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    Cigarette Smoke Activates Human Monocytes by an Oxidant-AP-1 Signaling Pathway: Implications for Steroid Resistance
    Matthew J. Walters, Mark J. Paul-Clark, Shaun K. McMaster, Kazuhiro Ito, Ian M. Adcock and Jane A. Mitchell
    Molecular Pharmacology November 2005, 68 (5) 1343-1353; DOI: https://doi.org/10.1124/mol.105.012591
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    Gq-Mediated Activation of c-Jun N-Terminal Kinase by the Gastrin-Releasing Peptide-Preferring Bombesin Receptor Is Inhibited upon Costimulation of the Gs-Coupled Dopamine D1 Receptor in COS-7 Cells
    Anthony S. L. Chan and Yung H. Wong
    Molecular Pharmacology November 2005, 68 (5) 1354-1364; DOI: https://doi.org/10.1124/mol.105.014548
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    Large-Scale Analysis of Genes that Alter Sensitivity to the Anticancer Drug Tirapazamine in Saccharomyces cerevisiae
    Karen Hellauer, Guillaume Lesage, Anne-Marie Sdicu and Bernard Turcotte
    Molecular Pharmacology November 2005, 68 (5) 1365-1375; DOI: https://doi.org/10.1124/mol.105.012963
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    Mice Lacking the α4 Nicotinic Receptor Subunit Fail to Modulate Dopaminergic Neuronal Arbors and Possess Impaired Dopamine Transporter Function
    C. L. Parish, J. Nunan, D. I. Finkelstein, F. N. McNamara, J. Y. Wong, J. L. Waddington, R. M. Brown, A. J. Lawrence, M. K. Horne and J. Drago
    Molecular Pharmacology November 2005, 68 (5) 1376-1386; DOI: https://doi.org/10.1124/mol.104.004820
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    Presynaptic Inhibition via a Phospholipase C- and Phosphatidylinositol Bisphosphate-Dependent Regulation of Neuronal Ca2+ Channels
    Stefan G. Lechner, Simon Hussl, Klaus W. Schicker, Helmut Drobny and Stefan Boehm
    Molecular Pharmacology November 2005, 68 (5) 1387-1396; DOI: https://doi.org/10.1124/mol.105.014886
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    Interaction of Organic Cations with a Newly Identified Plasma Membrane Monoamine Transporter
    Karen Engel and Joanne Wang
    Molecular Pharmacology November 2005, 68 (5) 1397-1407; DOI: https://doi.org/10.1124/mol.105.016832
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    Role of the Redox Protein Thioredoxin in Cytoprotective Mechanism Evoked by (-)-Deprenyl
    Tsugunobu Andoh, P. Boon Chock, Dennis L. Murphy and Chuang C. Chiueh
    Molecular Pharmacology November 2005, 68 (5) 1408-1414; DOI: https://doi.org/10.1124/mol.105.012302
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    Alkylation of β-Tubulin on Glu 198 by a Microtubule Disrupter
    Bernadette Bouchon, Christophe Chambon, Emmanuelle Mounetou, Janine Papon, Elisabeth Miot-Noirault, René C. Gaudreault, Jean-Claude Madelmont and Françoise Degoul
    Molecular Pharmacology November 2005, 68 (5) 1415-1422; DOI: https://doi.org/10.1124/mol.105.015586
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    Scavenger Receptors on Sinusoidal Liver Endothelial Cells Are Involved in the Uptake of Aldehyde-Modified Proteins
    Michael J. Duryee, Thomas L. Freeman, Monte S. Willis, Carlos D. Hunter, Bartlett C. Hamilton, Hiroshi Suzuki, Dean J. Tuma, Lynell W. Klassen and Geoffrey M. Thiele
    Molecular Pharmacology November 2005, 68 (5) 1423-1430; DOI: https://doi.org/10.1124/mol.105.016121
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    RIC-3 Enhances Functional Expression of Multiple Nicotinic Acetylcholine Receptor Subtypes in Mammalian Cells
    Stuart J. Lansdell, Veronica J. Gee, Patricia C. Harkness, Anne I. Doward, Elizabeth R. Baker, Alasdair J. Gibb and Neil S. Millar
    Molecular Pharmacology November 2005, 68 (5) 1431-1438; DOI: https://doi.org/10.1124/mol.105.017459
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    Protein PEGylation Decreases Observed Target Association Rates via a Dual Blocking Mechanism
    Susanne Kubetzko, Casim A. Sarkar and Andreas Plückthun
    Molecular Pharmacology November 2005, 68 (5) 1439-1454; DOI: https://doi.org/10.1124/mol.105.014910
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    Analysis of Human Multidrug Resistance Protein 1 (ABCC1) by Matrix-Assisted Laser Desorption Ionization/Time of Flight Mass Spectrometry: Toward Identification of Leukotriene C4 Binding Sites
    Peng Wu, Curtis J. Oleschuk, Qingcheng Mao, Bernd O. Keller, Roger G. Deeley and Susan P. C. Cole
    Molecular Pharmacology November 2005, 68 (5) 1455-1465; DOI: https://doi.org/10.1124/mol.105.016576
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    Mastoparan Changes the Cellular Localization of Gαq/11 and Gβ through Its Binding to Ganglioside in Lipid Rafts
    Jun Sugama, Satoko Ohkubo, Masanori Atsumi and Norimichi Nakahata
    Molecular Pharmacology November 2005, 68 (5) 1466-1474; DOI: https://doi.org/10.1124/mol.105.013524
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    Single-Channel Kinetic Analysis of Chimeric α7–5HT3A Receptors
    Diego Rayes, Guillermo Spitzmaul, Steven M. Sine and Cecilia Bouzat
    Molecular Pharmacology November 2005, 68 (5) 1475-1483; DOI: https://doi.org/10.1124/mol.105.015438
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    Allosteric Modulation of the Cannabinoid CB1 Receptor
    Martin R. Price, Gemma L. Baillie, Adèle Thomas, Lesley A. Stevenson, Morag Easson, Richard Goodwin, Adèle McLean, Lorraine McIntosh, Gillian Goodwin, Glenn Walker, Paul Westwood, Julia Marrs, Fiona Thomson, Phillip Cowley, Arthur Christopoulos, Roger G. Pertwee and Ruth A. Ross
    Molecular Pharmacology November 2005, 68 (5) 1484-1495; DOI: https://doi.org/10.1124/mol.105.016162
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    Selective Effects of the Anticancer Drug Yondelis (ET-743) on Cell-Cycle Promoters
    Mario Minuzzo, Michele Ceribelli, Marià Pitarque-Martì, Serena Borrelli, Eugenio Erba, Alberto diSilvio, Maurizio D'Incalci and Roberto Mantovani
    Molecular Pharmacology November 2005, 68 (5) 1496-1503; DOI: https://doi.org/10.1124/mol.105.013615
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Molecular Pharmacology: 68 (5)
Molecular Pharmacology
Vol. 68, Issue 5
1 Nov 2005
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