Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Molecular Pharmacology
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Molecular Pharmacology

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit molpharm on Facebook
  • Follow molpharm on Twitter
  • Follow molpharm on LinkedIn

Table of Contents

December 01, 2005; Volume 68,Issue 6

Articles

  • You have access
    Editor's Note
    Paul A. Insel
    Molecular Pharmacology December 2005, 68 (6) 1505; DOI: https://doi.org/10.1124/mol.68.6.1505
  • You have access
    Tweaking Agonist Efficacy at N-Methyl-d-aspartate Receptors by Site-Directed Mutagenesis
    Kasper B. Hansen, Rasmus P. Clausen, Esben J. Bjerrum, Christian Bechmann, Jeremy R. Greenwood, Caspar Christensen, Jesper L. Kristensen, Jan Egebjerg and Hans Bräuner-Osborne
    Molecular Pharmacology December 2005, 68 (6) 1510-1523; DOI: https://doi.org/10.1124/mol.105.014795
  • You have access
    Proton Activation Does Not Alter Antagonist Interaction with the Capsaicin-Binding Pocket of TRPV1
    Narender R. Gavva, Rami Tamir, Lana Klionsky, Mark H. Norman, Jean-Claude Louis, Kenneth D. Wild and James J. S. Treanor
    Molecular Pharmacology December 2005, 68 (6) 1524-1533; DOI: https://doi.org/10.1124/mol.105.015727
  • You have access
    Stereospecific Induction of Nuclear Factor-κB Activation by Isochamaejasmin
    Qinghai Tian, Jing Li, Xin Xie, Meiling Sun, Hairong Sang, Caihong Zhou, Tianying An, Lihong Hu, Richard D. Ye and Ming-Wei Wang
    Molecular Pharmacology December 2005, 68 (6) 1534-1542; DOI: https://doi.org/10.1124/mol.105.014720
  • You have access
    Vascular Targeting of Ocular Neovascularization with a Vascular Endothelial Growth Factor121/Gelonin Chimeric Protein
    Hideo Akiyama, Khalid A. Mohamedali, Raquel Lima e Silva, Shu Kachi, JiKui Shen, Christina Hatara, Naoyasu Umeda, Sean F. Hackett, Sadia Aslam, Melissa Krause, Hong Lai, Michael G. Rosenblum and Peter A. Campochiaro
    Molecular Pharmacology December 2005, 68 (6) 1543-1550; DOI: https://doi.org/10.1124/mol.105.015628
  • You have access
    Pharmacodynamics of the G-Quadruplex-Stabilizing Telomerase Inhibitor 3,11-Difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in Vitro: Activity in Human Tumor Cells Correlates with Telomere Length and Can Be Enhanced, or Antagonized, with Cytotoxic Agents
    Jennifer C. Cookson, Fangping Dai, Victoria Smith, Robert A. Heald, Charles A. Laughton, Malcolm F. G. Stevens and Angelika M. Burger
    Molecular Pharmacology December 2005, 68 (6) 1551-1558; DOI: https://doi.org/10.1124/mol.105.013300
  • You have access
    DNA Structural Similarity in the 2:1 Complexes of the Antitumor Drugs Trabectedin (Yondelis) and Chromomycin A3 with an Oligonucleotide Sequence Containing Two Adjacent TGG Binding Sites on Opposing Strands
    Esther Marco and Federico Gago
    Molecular Pharmacology December 2005, 68 (6) 1559-1567; DOI: https://doi.org/10.1124/mol.105.015685
  • You have access
    Involvement of IL-10 in Peroxisome Proliferator-Activated Receptor γ-Mediated Anti-Inflammatory Response in Asthma
    So Ri Kim, Kyung Sun Lee, Hee Sun Park, Seoung Ju Park, Kyung Hoon Min, Sun Mi Jin and Yong Chul Lee
    Molecular Pharmacology December 2005, 68 (6) 1568-1575; DOI: https://doi.org/10.1124/mol.105.017160
  • You have access
    N-Substituted 4-Aminobenzamides (Procainamide Analogs): An Assessment of Multiple Cellular Effects Concerning Ion Trapping
    Guillaume Morissette, Emmanuel Moreau, René C.-Gaudreault and François Marceau
    Molecular Pharmacology December 2005, 68 (6) 1576-1589; DOI: https://doi.org/10.1124/mol.105.016527
  • You have access
    Retinoid X Receptor α Regulates the Expression of Glutathione S-transferase Genes and Modulates Acetaminophen-Glutathione Conjugation in Mouse Liver
    Guoli Dai, Nathan Chou, Lin He, Maxwell A. Gyamfi, Alphonse J. Mendy, Angela L. Slitt, Curtis D. Klaassen and Yu-Jui Y. Wan
    Molecular Pharmacology December 2005, 68 (6) 1590-1596; DOI: https://doi.org/10.1124/mol.105.013680
  • You have access
    Atypical Muscarinic Allosteric Modulation: Cooperativity between Modulators and Their Atypical Binding Topology in Muscarinic M2 and M2/M5 Chimeric Receptors
    Christian Tränkle, Andreas Dittmann, Uwe Schulz, Oliver Weyand, Stefan Buller, Kirstin Jöhren, Eberhard Heller, Nigel J. M. Birdsall, Ulrike Holzgrabe, John Ellis, Hans Dieter Höltje and Klaus Mohr
    Molecular Pharmacology December 2005, 68 (6) 1597-1610; DOI: https://doi.org/10.1124/mol.105.017707
  • You have access
    Molecular Modeling of Local Anesthetic Drug Binding by Voltage-Gated Sodium Channels
    Gregory M. Lipkind and Harry A. Fozzard
    Molecular Pharmacology December 2005, 68 (6) 1611-1622; DOI: https://doi.org/10.1124/mol.105.014803
  • You have access
    (-)-7′-Isothiocyanato-11-hydroxy-1′,1′-dimethylheptylhexahydrocannabinol (AM841), a High-Affinity Electrophilic Ligand, Interacts Covalently with a Cysteine in Helix Six and Activates the CB1 Cannabinoid Receptor
    Robert P. Picone, Atmaram D. Khanolkar, Wei Xu, Lionel A. Ayotte, Ganesh A. Thakur, Dow P. Hurst, Mary E. Abood, Patricia H. Reggio, Donna J. Fournier and Alexandros Makriyannis
    Molecular Pharmacology December 2005, 68 (6) 1623-1635; DOI: https://doi.org/10.1124/mol.105.014407
  • You have access
    Gemcitabine-Induced Activation of Checkpoint Signaling Pathways That Affect Tumor Cell Survival
    Larry M. Karnitz, Karen S. Flatten, Jill M. Wagner, David Loegering, Jennifer S. Hackbarth, Sonnet J. H. Arlander, Benjamin T. Vroman, M. Bijoy Thomas, Yong-Un Baek, Kevin M. Hopkins, Howard B. Lieberman, Junjie Chen, William A. Cliby and Scott H. Kaufmann
    Molecular Pharmacology December 2005, 68 (6) 1636-1644; DOI: https://doi.org/10.1124/mol.105.012716
  • You have access
    Evidence for a Secondary State of the Human β3-Adrenoceptor
    Jillian G. Baker
    Molecular Pharmacology December 2005, 68 (6) 1645-1655; DOI: https://doi.org/10.1124/mol.105.015461
  • You have access
    Nicotinic Cholinergic Receptors in the Rat Retina: Simple and Mixed Heteromeric Subtypes
    Andrea M. Marritt, Brandon C. Cox, Robert P. Yasuda, J. Michael McIntosh, Yingxian Xiao, Barry B. Wolfe and Kenneth J. Kellar
    Molecular Pharmacology December 2005, 68 (6) 1656-1668; DOI: https://doi.org/10.1124/mol.105.012369
  • You have access
    Mutations of a Conserved Lysine Residue in the N-Terminal Domain of α7 Nicotinic Receptors Affect Gating and Binding of Nicotinic Agonists
    Manuel Criado, José Mulet, José A. Bernal, Susana Gerber, Salvador Sala and Francisco Sala
    Molecular Pharmacology December 2005, 68 (6) 1669-1677; DOI: https://doi.org/10.1124/mol.105.015446
  • You have access
    Intracellular cAMP and Calcium Signaling by Serotonin in Mouse Cumulus-Oocyte Complexes
    Pascal Amireault and François Dubé
    Molecular Pharmacology December 2005, 68 (6) 1678-1687; DOI: https://doi.org/10.1124/mol.104.010124
  • You have access
    Induction of δ Opioid Receptor Function by Up-Regulation of Membrane Receptors in Mouse Primary Afferent Neurons
    Wendy Walwyn, Nigel T. Maidment, Matthew Sanders, Christopher J. Evans, Brigitte L. Kieffer and Tim G. Hales
    Molecular Pharmacology December 2005, 68 (6) 1688-1698; DOI: https://doi.org/10.1124/mol.105.014829
  • You have access
    Activation of the Unfolded Protein Response Is Necessary and Sufficient for Reducing Topoisomerase IIα Protein Levels and Decreasing Sensitivity to Topoisomerase-Targeted Drugs
    Miranda D. Gray, Melissa Mann, John L. Nitiss and Linda M. Hendershot
    Molecular Pharmacology December 2005, 68 (6) 1699-1707; DOI: https://doi.org/10.1124/mol.105.014753
  • You have access
    Effects of Drugs with Muscle-Related Side Effects and Affinity for Calsequestrin on the Calcium Regulatory Function of Sarcoplasmic Reticulum Microsomes
    EunJung Kim, Maggie Tam, William F. Siems and ChulHee Kang
    Molecular Pharmacology December 2005, 68 (6) 1708-1715; DOI: https://doi.org/10.1124/mol.105.016253
  • You have access
    Sulfated Polymannuroguluronate, a Novel Anti-AIDS Drug Candidate, Inhibits T Cell Apoptosis by Combating Oxidative Damage of Mitochondria
    Benchun Miao, Jing Li, Xueyan Fu, Li Gan, Xianliang Xin and Meiyu Geng
    Molecular Pharmacology December 2005, 68 (6) 1716-1727; DOI: https://doi.org/10.1124/mol.105.015412
  • You have access
    Identification and Selective Inhibition of the Channel Mode of the Neuronal GABA Transporter 1
    Stephan Krause and Wolfgang Schwarz
    Molecular Pharmacology December 2005, 68 (6) 1728-1735; DOI: https://doi.org/10.1124/mol.105.013870
  • You have access
    Antihypertensive 1,4-Dihydropyridines as Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator Channel Gating Defect Caused by Cystic Fibrosis Mutations
    Nicoletta Pedemonte, Tullia Diena, Emanuela Caci, Erika Nieddu, Mauro Mazzei, Roberto Ravazzolo, Olga Zegarra-Moran and Luis J. V. Galietta
    Molecular Pharmacology December 2005, 68 (6) 1736-1746; DOI: https://doi.org/10.1124/mol.105.015149
  • You have access
    A Novel Group of Genes Regulates Susceptibility to Antineoplastic Drugs in Highly Tumorigenic Breast Cancer Cells
    Julia C. Mallory, Gerard Crudden, Amelia Oliva, Christopher Saunders, Arnold Stromberg and Rolf J. Craven
    Molecular Pharmacology December 2005, 68 (6) 1747-1756; DOI: https://doi.org/10.1124/mol.105.016519
  • You have access
    Direct Stimulation of KATP Channels by Exogenous and Endogenous Hydrogen Sulfide in Vascular Smooth Muscle Cells
    Guanghua Tang, Lingyun Wu, Wenbin Liang and Rui Wang
    Molecular Pharmacology December 2005, 68 (6) 1757-1764; DOI: https://doi.org/10.1124/mol.105.017467
  • You have access
    Long-Lasting Impairment of Associative Learning Is Correlated with a Dysfunction of N-Methyl-d-aspartate-Extracellular Signaling-Regulated Kinase Signaling in Mice after Withdrawal from Repeated Administration of Phencyclidine
    Takeshi Enomoto, Yukihiro Noda, Akihiro Mouri, Eun-Joo Shin, Dayong Wang, Rina Murai, Kazuo Hotta, Hiroshi Furukawa, Atsumi Nitta, Hyoung-Chun Kim and Toshitaka Nabeshima
    Molecular Pharmacology December 2005, 68 (6) 1765-1774; DOI: https://doi.org/10.1124/mol.105.011304
  • You have access
    Characterization of the First Potent and Selective PDE9 Inhibitor Using a cGMP Reporter Cell Line
    Frank Wunder, Adrian Tersteegen, Annegret Rebmann, Christina Erb, Thomas Fahrig and Martin Hendrix
    Molecular Pharmacology December 2005, 68 (6) 1775-1781; DOI: https://doi.org/10.1124/mol.105.017608
  • You have access
    1,1-Bis(3′-indolyl)-1-(p-substitutedphenyl)methanes Are Peroxisome Proliferator-Activated Receptor γ Agonists but Decrease HCT-116 Colon Cancer Cell Survival through Receptor-Independent Activation of Early Growth Response-1 and Nonsteroidal Anti-Inflammatory Drug-Activated Gene-1
    Sudhakar Chintharlapalli, Sabitha Papineni, Seung Joon Baek, Shengxi Liu and Stephen Safe
    Molecular Pharmacology December 2005, 68 (6) 1782-1792; DOI: https://doi.org/10.1124/mol.105.017046
  • You have access
    A Close Structural Analog of 2-Methyl-6-(phenylethynyl)-pyridine Acts as a Neutral Allosteric Site Ligand on Metabotropic Glutamate Receptor Subtype 5 and Blocks the Effects of Multiple Allosteric Modulators
    Alice L. Rodriguez, Yi Nong, Nishant K. Sekaran, David Alagille, Gilles D. Tamagnan and P. Jeffrey Conn
    Molecular Pharmacology December 2005, 68 (6) 1793-1802; DOI: https://doi.org/10.1124/mol.105.016139
  • You have access
    Inhibition of the Catalytic Activity of Hypoxia-Inducible Factor-1α-Prolyl-Hydroxylase 2 by a MYND-Type Zinc Finger
    Kyung-Ok Choi, Taekyong Lee, Naery Lee, Ji-Hyun Kim, Eun Gyeong Yang, Jung Min Yoon, Jin Hwan Kim, Tae Gyu Lee and Hyunsung Park
    Molecular Pharmacology December 2005, 68 (6) 1803-1809; DOI: https://doi.org/10.1124/mol.105.015271
  • You have access
    Redox Regulation of Cdc25B by Cell-Active Quinolinediones
    Marni Brisson, Theresa Nguyen, Peter Wipf, Beomjun Joo, Billy W. Day, John S. Skoko, Emanuel M. Schreiber, Caleb Foster, Pallavi Bansal and John S. Lazo
    Molecular Pharmacology December 2005, 68 (6) 1810-1820; DOI: https://doi.org/10.1124/mol.105.016360
  • You have access
    A Key Serine for the GTPase-Activating Protein Function of Regulator of G Protein Signaling Proteins Is Not a General Target for 14-3-3 Interactions
    Richard J. Ward and Graeme Milligan
    Molecular Pharmacology December 2005, 68 (6) 1821-1830; DOI: https://doi.org/10.1124/mol.105.015073
  • You have access
    Apoptosis Induced by a New Member of Saponin Family Is Mediated through Caspase-8-Dependent Cleavage of Bcl-2
    Jianbei Zhu, Lei Xiong, Biao Yu and Jiarui Wu
    Molecular Pharmacology December 2005, 68 (6) 1831-1838; DOI: https://doi.org/10.1124/mol.105.015826
  • You have access
    Nicotine Acts as a Pharmacological Chaperone to Up-Regulate Human α4β2 Acetylcholine Receptors
    A. Kuryatov, J. Luo, J. Cooper and J. Lindstrom
    Molecular Pharmacology December 2005, 68 (6) 1839-1851; DOI: https://doi.org/10.1124/mol.105.012419
  • You have access
    Opposite Effects of Histone Deacetylase Inhibitors on Glucocorticoid and Estrogen Signaling in Human Endometrial Ishikawa Cells
    Walter Rocha, Rocio Sanchez, Julie Deschênes, Anick Auger, Elise Hébert, John H. White and Sylvie Mader
    Molecular Pharmacology December 2005, 68 (6) 1852-1862; DOI: https://doi.org/10.1124/mol.105.014514
  • You have access
    An α7 Nicotinic Acetylcholine Receptor Gain-of-Function Mutant That Retains Pharmacological Fidelity
    Andon N. Placzek, Francesca Grassi, Edwin M Meyer and Roger L. Papke
    Molecular Pharmacology December 2005, 68 (6) 1863-1876; DOI: https://doi.org/10.1124/mol.105.016402

Perspective

  • You have access
    Allosteric Binding Sites on Muscarinic Acetylcholine Receptors
    Jürgen Wess
    Molecular Pharmacology December 2005, 68 (6) 1506-1509; DOI: https://doi.org/10.1124/mol.105.019141
Back to top
PreviousNext

In this issue

Molecular Pharmacology: 68 (6)
Molecular Pharmacology
Vol. 68, Issue 6
1 Dec 2005
  • Table of Contents
  • About the Cover
  • Index by author
Sign up for alerts

Jump to

  • Articles
  • Perspective
  • Most Read
Loading
  • Proteomic Analysis of GPCR Cell Biology
  • Phosphoproteomic Analysis of cAMP-Dependent Pathways
  • Phosphoproteomic Identification of Signaling Pathways
  • How Many G Protein-Coupled Receptors are Drug Targets?
  • Characterization of GRD and LCCH3 from Human Louse
More...
Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About Molecular Pharmacology
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Journal of Pharmacology and Experimental Therapeutics
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-0111 (Online)

Copyright © 2022 by the American Society for Pharmacology and Experimental Therapeutics