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Index by author

December 01, 2005; Volume 68,Issue 6

A

  1. Abood, Mary E.

    1. (-)-7′-Isothiocyanato-11-hydroxy-1′,1′-dimethylheptylhexahydrocannabinol (AM841), a High-Affinity Electrophilic Ligand, Interacts Covalently with a Cysteine in Helix Six and Activates the CB1 Cannabinoid Receptor
      Robert P. Picone, Atmaram D. Khanolkar, Wei Xu, Lionel A. Ayotte, Ganesh A. Thakur, Dow P. Hurst, Mary E. Abood, Patricia H. Reggio, Donna J. Fournier and Alexandros Makriyannis
      Molecular Pharmacology December 2005, 68 (6) 1623-1635; DOI: https://doi.org/10.1124/mol.105.014407

  2. Akiyama, Hideo

    1. Vascular Targeting of Ocular Neovascularization with a Vascular Endothelial Growth Factor121/Gelonin Chimeric Protein
      Hideo Akiyama, Khalid A. Mohamedali, Raquel Lima e Silva, Shu Kachi, JiKui Shen, Christina Hatara, Naoyasu Umeda, Sean F. Hackett, Sadia Aslam, Melissa Krause, Hong Lai, Michael G. Rosenblum and Peter A. Campochiaro
      Molecular Pharmacology December 2005, 68 (6) 1543-1550; DOI: https://doi.org/10.1124/mol.105.015628

  3. Alagille, David

    1. A Close Structural Analog of 2-Methyl-6-(phenylethynyl)-pyridine Acts as a Neutral Allosteric Site Ligand on Metabotropic Glutamate Receptor Subtype 5 and Blocks the Effects of Multiple Allosteric Modulators
      Alice L. Rodriguez, Yi Nong, Nishant K. Sekaran, David Alagille, Gilles D. Tamagnan and P. Jeffrey Conn
      Molecular Pharmacology December 2005, 68 (6) 1793-1802; DOI: https://doi.org/10.1124/mol.105.016139

  4. Amireault, Pascal

    1. Intracellular cAMP and Calcium Signaling by Serotonin in Mouse Cumulus-Oocyte Complexes
      Pascal Amireault and François Dubé
      Molecular Pharmacology December 2005, 68 (6) 1678-1687; DOI: https://doi.org/10.1124/mol.104.010124

  5. An, Tianying

    1. Stereospecific Induction of Nuclear Factor-κB Activation by Isochamaejasmin
      Qinghai Tian, Jing Li, Xin Xie, Meiling Sun, Hairong Sang, Caihong Zhou, Tianying An, Lihong Hu, Richard D. Ye and Ming-Wei Wang
      Molecular Pharmacology December 2005, 68 (6) 1534-1542; DOI: https://doi.org/10.1124/mol.105.014720

  6. Arlander, Sonnet J. H.

    1. Gemcitabine-Induced Activation of Checkpoint Signaling Pathways That Affect Tumor Cell Survival
      Larry M. Karnitz, Karen S. Flatten, Jill M. Wagner, David Loegering, Jennifer S. Hackbarth, Sonnet J. H. Arlander, Benjamin T. Vroman, M. Bijoy Thomas, Yong-Un Baek, Kevin M. Hopkins, Howard B. Lieberman, Junjie Chen, William A. Cliby and Scott H. Kaufmann
      Molecular Pharmacology December 2005, 68 (6) 1636-1644; DOI: https://doi.org/10.1124/mol.105.012716

  7. Aslam, Sadia

    1. Vascular Targeting of Ocular Neovascularization with a Vascular Endothelial Growth Factor121/Gelonin Chimeric Protein
      Hideo Akiyama, Khalid A. Mohamedali, Raquel Lima e Silva, Shu Kachi, JiKui Shen, Christina Hatara, Naoyasu Umeda, Sean F. Hackett, Sadia Aslam, Melissa Krause, Hong Lai, Michael G. Rosenblum and Peter A. Campochiaro
      Molecular Pharmacology December 2005, 68 (6) 1543-1550; DOI: https://doi.org/10.1124/mol.105.015628

  8. Auger, Anick

    1. Opposite Effects of Histone Deacetylase Inhibitors on Glucocorticoid and Estrogen Signaling in Human Endometrial Ishikawa Cells
      Walter Rocha, Rocio Sanchez, Julie Deschênes, Anick Auger, Elise Hébert, John H. White and Sylvie Mader
      Molecular Pharmacology December 2005, 68 (6) 1852-1862; DOI: https://doi.org/10.1124/mol.105.014514

  9. Ayotte, Lionel A.

    1. (-)-7′-Isothiocyanato-11-hydroxy-1′,1′-dimethylheptylhexahydrocannabinol (AM841), a High-Affinity Electrophilic Ligand, Interacts Covalently with a Cysteine in Helix Six and Activates the CB1 Cannabinoid Receptor
      Robert P. Picone, Atmaram D. Khanolkar, Wei Xu, Lionel A. Ayotte, Ganesh A. Thakur, Dow P. Hurst, Mary E. Abood, Patricia H. Reggio, Donna J. Fournier and Alexandros Makriyannis
      Molecular Pharmacology December 2005, 68 (6) 1623-1635; DOI: https://doi.org/10.1124/mol.105.014407

B

  1. Baek, Seung Joon

    1. 1,1-Bis(3′-indolyl)-1-(p-substitutedphenyl)methanes Are Peroxisome Proliferator-Activated Receptor γ Agonists but Decrease HCT-116 Colon Cancer Cell Survival through Receptor-Independent Activation of Early Growth Response-1 and Nonsteroidal Anti-Inflammatory Drug-Activated Gene-1
      Sudhakar Chintharlapalli, Sabitha Papineni, Seung Joon Baek, Shengxi Liu and Stephen Safe
      Molecular Pharmacology December 2005, 68 (6) 1782-1792; DOI: https://doi.org/10.1124/mol.105.017046

  2. Baek, Yong-Un

    1. Gemcitabine-Induced Activation of Checkpoint Signaling Pathways That Affect Tumor Cell Survival
      Larry M. Karnitz, Karen S. Flatten, Jill M. Wagner, David Loegering, Jennifer S. Hackbarth, Sonnet J. H. Arlander, Benjamin T. Vroman, M. Bijoy Thomas, Yong-Un Baek, Kevin M. Hopkins, Howard B. Lieberman, Junjie Chen, William A. Cliby and Scott H. Kaufmann
      Molecular Pharmacology December 2005, 68 (6) 1636-1644; DOI: https://doi.org/10.1124/mol.105.012716

  3. Baker, Jillian G.

    1. Evidence for a Secondary State of the Human β3-Adrenoceptor
      Jillian G. Baker
      Molecular Pharmacology December 2005, 68 (6) 1645-1655; DOI: https://doi.org/10.1124/mol.105.015461

  4. Bansal, Pallavi

    1. Redox Regulation of Cdc25B by Cell-Active Quinolinediones
      Marni Brisson, Theresa Nguyen, Peter Wipf, Beomjun Joo, Billy W. Day, John S. Skoko, Emanuel M. Schreiber, Caleb Foster, Pallavi Bansal and John S. Lazo
      Molecular Pharmacology December 2005, 68 (6) 1810-1820; DOI: https://doi.org/10.1124/mol.105.016360

  5. Bechmann, Christian

    1. Tweaking Agonist Efficacy at N-Methyl-d-aspartate Receptors by Site-Directed Mutagenesis
      Kasper B. Hansen, Rasmus P. Clausen, Esben J. Bjerrum, Christian Bechmann, Jeremy R. Greenwood, Caspar Christensen, Jesper L. Kristensen, Jan Egebjerg and Hans Bräuner-Osborne
      Molecular Pharmacology December 2005, 68 (6) 1510-1523; DOI: https://doi.org/10.1124/mol.105.014795

  6. Bernal, José A.

    1. Mutations of a Conserved Lysine Residue in the N-Terminal Domain of α7 Nicotinic Receptors Affect Gating and Binding of Nicotinic Agonists
      Manuel Criado, José Mulet, José A. Bernal, Susana Gerber, Salvador Sala and Francisco Sala
      Molecular Pharmacology December 2005, 68 (6) 1669-1677; DOI: https://doi.org/10.1124/mol.105.015446

  7. Birdsall, Nigel J. M.

    1. Atypical Muscarinic Allosteric Modulation: Cooperativity between Modulators and Their Atypical Binding Topology in Muscarinic M2 and M2/M5 Chimeric Receptors
      Christian Tränkle, Andreas Dittmann, Uwe Schulz, Oliver Weyand, Stefan Buller, Kirstin Jöhren, Eberhard Heller, Nigel J. M. Birdsall, Ulrike Holzgrabe, John Ellis, Hans Dieter Höltje and Klaus Mohr
      Molecular Pharmacology December 2005, 68 (6) 1597-1610; DOI: https://doi.org/10.1124/mol.105.017707

  8. Bjerrum, Esben J.

    1. Tweaking Agonist Efficacy at N-Methyl-d-aspartate Receptors by Site-Directed Mutagenesis
      Kasper B. Hansen, Rasmus P. Clausen, Esben J. Bjerrum, Christian Bechmann, Jeremy R. Greenwood, Caspar Christensen, Jesper L. Kristensen, Jan Egebjerg and Hans Bräuner-Osborne
      Molecular Pharmacology December 2005, 68 (6) 1510-1523; DOI: https://doi.org/10.1124/mol.105.014795

  9. Bräuner-Osborne, Hans

    1. Tweaking Agonist Efficacy at N-Methyl-d-aspartate Receptors by Site-Directed Mutagenesis
      Kasper B. Hansen, Rasmus P. Clausen, Esben J. Bjerrum, Christian Bechmann, Jeremy R. Greenwood, Caspar Christensen, Jesper L. Kristensen, Jan Egebjerg and Hans Bräuner-Osborne
      Molecular Pharmacology December 2005, 68 (6) 1510-1523; DOI: https://doi.org/10.1124/mol.105.014795

  10. Brisson, Marni

    1. Redox Regulation of Cdc25B by Cell-Active Quinolinediones
      Marni Brisson, Theresa Nguyen, Peter Wipf, Beomjun Joo, Billy W. Day, John S. Skoko, Emanuel M. Schreiber, Caleb Foster, Pallavi Bansal and John S. Lazo
      Molecular Pharmacology December 2005, 68 (6) 1810-1820; DOI: https://doi.org/10.1124/mol.105.016360

  11. Buller, Stefan

    1. Atypical Muscarinic Allosteric Modulation: Cooperativity between Modulators and Their Atypical Binding Topology in Muscarinic M2 and M2/M5 Chimeric Receptors
      Christian Tränkle, Andreas Dittmann, Uwe Schulz, Oliver Weyand, Stefan Buller, Kirstin Jöhren, Eberhard Heller, Nigel J. M. Birdsall, Ulrike Holzgrabe, John Ellis, Hans Dieter Höltje and Klaus Mohr
      Molecular Pharmacology December 2005, 68 (6) 1597-1610; DOI: https://doi.org/10.1124/mol.105.017707

  12. Burger, Angelika M.

    1. Pharmacodynamics of the G-Quadruplex-Stabilizing Telomerase Inhibitor 3,11-Difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in Vitro: Activity in Human Tumor Cells Correlates with Telomere Length and Can Be Enhanced, or Antagonized, with Cytotoxic Agents
      Jennifer C. Cookson, Fangping Dai, Victoria Smith, Robert A. Heald, Charles A. Laughton, Malcolm F. G. Stevens and Angelika M. Burger
      Molecular Pharmacology December 2005, 68 (6) 1551-1558; DOI: https://doi.org/10.1124/mol.105.013300

C

  1. C.-Gaudreault, René

    1. N-Substituted 4-Aminobenzamides (Procainamide Analogs): An Assessment of Multiple Cellular Effects Concerning Ion Trapping
      Guillaume Morissette, Emmanuel Moreau, René C.-Gaudreault and François Marceau
      Molecular Pharmacology December 2005, 68 (6) 1576-1589; DOI: https://doi.org/10.1124/mol.105.016527

  2. Caci, Emanuela

    1. Antihypertensive 1,4-Dihydropyridines as Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator Channel Gating Defect Caused by Cystic Fibrosis Mutations
      Nicoletta Pedemonte, Tullia Diena, Emanuela Caci, Erika Nieddu, Mauro Mazzei, Roberto Ravazzolo, Olga Zegarra-Moran and Luis J. V. Galietta
      Molecular Pharmacology December 2005, 68 (6) 1736-1746; DOI: https://doi.org/10.1124/mol.105.015149

  3. Campochiaro, Peter A.

    1. Vascular Targeting of Ocular Neovascularization with a Vascular Endothelial Growth Factor121/Gelonin Chimeric Protein
      Hideo Akiyama, Khalid A. Mohamedali, Raquel Lima e Silva, Shu Kachi, JiKui Shen, Christina Hatara, Naoyasu Umeda, Sean F. Hackett, Sadia Aslam, Melissa Krause, Hong Lai, Michael G. Rosenblum and Peter A. Campochiaro
      Molecular Pharmacology December 2005, 68 (6) 1543-1550; DOI: https://doi.org/10.1124/mol.105.015628

  4. Chen, Junjie

    1. Gemcitabine-Induced Activation of Checkpoint Signaling Pathways That Affect Tumor Cell Survival
      Larry M. Karnitz, Karen S. Flatten, Jill M. Wagner, David Loegering, Jennifer S. Hackbarth, Sonnet J. H. Arlander, Benjamin T. Vroman, M. Bijoy Thomas, Yong-Un Baek, Kevin M. Hopkins, Howard B. Lieberman, Junjie Chen, William A. Cliby and Scott H. Kaufmann
      Molecular Pharmacology December 2005, 68 (6) 1636-1644; DOI: https://doi.org/10.1124/mol.105.012716

  5. Chintharlapalli, Sudhakar

    1. 1,1-Bis(3′-indolyl)-1-(p-substitutedphenyl)methanes Are Peroxisome Proliferator-Activated Receptor γ Agonists but Decrease HCT-116 Colon Cancer Cell Survival through Receptor-Independent Activation of Early Growth Response-1 and Nonsteroidal Anti-Inflammatory Drug-Activated Gene-1
      Sudhakar Chintharlapalli, Sabitha Papineni, Seung Joon Baek, Shengxi Liu and Stephen Safe
      Molecular Pharmacology December 2005, 68 (6) 1782-1792; DOI: https://doi.org/10.1124/mol.105.017046

  6. Choi, Kyung-Ok

    1. Inhibition of the Catalytic Activity of Hypoxia-Inducible Factor-1α-Prolyl-Hydroxylase 2 by a MYND-Type Zinc Finger
      Kyung-Ok Choi, Taekyong Lee, Naery Lee, Ji-Hyun Kim, Eun Gyeong Yang, Jung Min Yoon, Jin Hwan Kim, Tae Gyu Lee and Hyunsung Park
      Molecular Pharmacology December 2005, 68 (6) 1803-1809; DOI: https://doi.org/10.1124/mol.105.015271

  7. Chou, Nathan

    1. Retinoid X Receptor α Regulates the Expression of Glutathione S-transferase Genes and Modulates Acetaminophen-Glutathione Conjugation in Mouse Liver
      Guoli Dai, Nathan Chou, Lin He, Maxwell A. Gyamfi, Alphonse J. Mendy, Angela L. Slitt, Curtis D. Klaassen and Yu-Jui Y. Wan
      Molecular Pharmacology December 2005, 68 (6) 1590-1596; DOI: https://doi.org/10.1124/mol.105.013680

  8. Christensen, Caspar

    1. Tweaking Agonist Efficacy at N-Methyl-d-aspartate Receptors by Site-Directed Mutagenesis
      Kasper B. Hansen, Rasmus P. Clausen, Esben J. Bjerrum, Christian Bechmann, Jeremy R. Greenwood, Caspar Christensen, Jesper L. Kristensen, Jan Egebjerg and Hans Bräuner-Osborne
      Molecular Pharmacology December 2005, 68 (6) 1510-1523; DOI: https://doi.org/10.1124/mol.105.014795

  9. Clausen, Rasmus P.

    1. Tweaking Agonist Efficacy at N-Methyl-d-aspartate Receptors by Site-Directed Mutagenesis
      Kasper B. Hansen, Rasmus P. Clausen, Esben J. Bjerrum, Christian Bechmann, Jeremy R. Greenwood, Caspar Christensen, Jesper L. Kristensen, Jan Egebjerg and Hans Bräuner-Osborne
      Molecular Pharmacology December 2005, 68 (6) 1510-1523; DOI: https://doi.org/10.1124/mol.105.014795

  10. Cliby, William A.

    1. Gemcitabine-Induced Activation of Checkpoint Signaling Pathways That Affect Tumor Cell Survival
      Larry M. Karnitz, Karen S. Flatten, Jill M. Wagner, David Loegering, Jennifer S. Hackbarth, Sonnet J. H. Arlander, Benjamin T. Vroman, M. Bijoy Thomas, Yong-Un Baek, Kevin M. Hopkins, Howard B. Lieberman, Junjie Chen, William A. Cliby and Scott H. Kaufmann
      Molecular Pharmacology December 2005, 68 (6) 1636-1644; DOI: https://doi.org/10.1124/mol.105.012716

  11. Conn, P. Jeffrey

    1. A Close Structural Analog of 2-Methyl-6-(phenylethynyl)-pyridine Acts as a Neutral Allosteric Site Ligand on Metabotropic Glutamate Receptor Subtype 5 and Blocks the Effects of Multiple Allosteric Modulators
      Alice L. Rodriguez, Yi Nong, Nishant K. Sekaran, David Alagille, Gilles D. Tamagnan and P. Jeffrey Conn
      Molecular Pharmacology December 2005, 68 (6) 1793-1802; DOI: https://doi.org/10.1124/mol.105.016139

  12. Cookson, Jennifer C.

    1. Pharmacodynamics of the G-Quadruplex-Stabilizing Telomerase Inhibitor 3,11-Difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in Vitro: Activity in Human Tumor Cells Correlates with Telomere Length and Can Be Enhanced, or Antagonized, with Cytotoxic Agents
      Jennifer C. Cookson, Fangping Dai, Victoria Smith, Robert A. Heald, Charles A. Laughton, Malcolm F. G. Stevens and Angelika M. Burger
      Molecular Pharmacology December 2005, 68 (6) 1551-1558; DOI: https://doi.org/10.1124/mol.105.013300

  13. Cooper, J.

    1. Nicotine Acts as a Pharmacological Chaperone to Up-Regulate Human α4β2 Acetylcholine Receptors
      A. Kuryatov, J. Luo, J. Cooper and J. Lindstrom
      Molecular Pharmacology December 2005, 68 (6) 1839-1851; DOI: https://doi.org/10.1124/mol.105.012419

  14. Cox, Brandon C.

    1. Nicotinic Cholinergic Receptors in the Rat Retina: Simple and Mixed Heteromeric Subtypes
      Andrea M. Marritt, Brandon C. Cox, Robert P. Yasuda, J. Michael McIntosh, Yingxian Xiao, Barry B. Wolfe and Kenneth J. Kellar
      Molecular Pharmacology December 2005, 68 (6) 1656-1668; DOI: https://doi.org/10.1124/mol.105.012369

  15. Craven, Rolf J.

    1. A Novel Group of Genes Regulates Susceptibility to Antineoplastic Drugs in Highly Tumorigenic Breast Cancer Cells
      Julia C. Mallory, Gerard Crudden, Amelia Oliva, Christopher Saunders, Arnold Stromberg and Rolf J. Craven
      Molecular Pharmacology December 2005, 68 (6) 1747-1756; DOI: https://doi.org/10.1124/mol.105.016519

  16. Criado, Manuel

    1. Mutations of a Conserved Lysine Residue in the N-Terminal Domain of α7 Nicotinic Receptors Affect Gating and Binding of Nicotinic Agonists
      Manuel Criado, José Mulet, José A. Bernal, Susana Gerber, Salvador Sala and Francisco Sala
      Molecular Pharmacology December 2005, 68 (6) 1669-1677; DOI: https://doi.org/10.1124/mol.105.015446

  17. Crudden, Gerard

    1. A Novel Group of Genes Regulates Susceptibility to Antineoplastic Drugs in Highly Tumorigenic Breast Cancer Cells
      Julia C. Mallory, Gerard Crudden, Amelia Oliva, Christopher Saunders, Arnold Stromberg and Rolf J. Craven
      Molecular Pharmacology December 2005, 68 (6) 1747-1756; DOI: https://doi.org/10.1124/mol.105.016519

D

  1. Dai, Fangping

    1. Pharmacodynamics of the G-Quadruplex-Stabilizing Telomerase Inhibitor 3,11-Difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in Vitro: Activity in Human Tumor Cells Correlates with Telomere Length and Can Be Enhanced, or Antagonized, with Cytotoxic Agents
      Jennifer C. Cookson, Fangping Dai, Victoria Smith, Robert A. Heald, Charles A. Laughton, Malcolm F. G. Stevens and Angelika M. Burger
      Molecular Pharmacology December 2005, 68 (6) 1551-1558; DOI: https://doi.org/10.1124/mol.105.013300

  2. Dai, Guoli

    1. Retinoid X Receptor α Regulates the Expression of Glutathione S-transferase Genes and Modulates Acetaminophen-Glutathione Conjugation in Mouse Liver
      Guoli Dai, Nathan Chou, Lin He, Maxwell A. Gyamfi, Alphonse J. Mendy, Angela L. Slitt, Curtis D. Klaassen and Yu-Jui Y. Wan
      Molecular Pharmacology December 2005, 68 (6) 1590-1596; DOI: https://doi.org/10.1124/mol.105.013680

  3. Day, Billy W.

    1. Redox Regulation of Cdc25B by Cell-Active Quinolinediones
      Marni Brisson, Theresa Nguyen, Peter Wipf, Beomjun Joo, Billy W. Day, John S. Skoko, Emanuel M. Schreiber, Caleb Foster, Pallavi Bansal and John S. Lazo
      Molecular Pharmacology December 2005, 68 (6) 1810-1820; DOI: https://doi.org/10.1124/mol.105.016360

  4. Deschênes, Julie

    1. Opposite Effects of Histone Deacetylase Inhibitors on Glucocorticoid and Estrogen Signaling in Human Endometrial Ishikawa Cells
      Walter Rocha, Rocio Sanchez, Julie Deschênes, Anick Auger, Elise Hébert, John H. White and Sylvie Mader
      Molecular Pharmacology December 2005, 68 (6) 1852-1862; DOI: https://doi.org/10.1124/mol.105.014514

  5. Diena, Tullia

    1. Antihypertensive 1,4-Dihydropyridines as Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator Channel Gating Defect Caused by Cystic Fibrosis Mutations
      Nicoletta Pedemonte, Tullia Diena, Emanuela Caci, Erika Nieddu, Mauro Mazzei, Roberto Ravazzolo, Olga Zegarra-Moran and Luis J. V. Galietta
      Molecular Pharmacology December 2005, 68 (6) 1736-1746; DOI: https://doi.org/10.1124/mol.105.015149

  6. Dittmann, Andreas

    1. Atypical Muscarinic Allosteric Modulation: Cooperativity between Modulators and Their Atypical Binding Topology in Muscarinic M2 and M2/M5 Chimeric Receptors
      Christian Tränkle, Andreas Dittmann, Uwe Schulz, Oliver Weyand, Stefan Buller, Kirstin Jöhren, Eberhard Heller, Nigel J. M. Birdsall, Ulrike Holzgrabe, John Ellis, Hans Dieter Höltje and Klaus Mohr
      Molecular Pharmacology December 2005, 68 (6) 1597-1610; DOI: https://doi.org/10.1124/mol.105.017707

  7. Dubé, François

    1. Intracellular cAMP and Calcium Signaling by Serotonin in Mouse Cumulus-Oocyte Complexes
      Pascal Amireault and François Dubé
      Molecular Pharmacology December 2005, 68 (6) 1678-1687; DOI: https://doi.org/10.1124/mol.104.010124

E

  1. Egebjerg, Jan

    1. Tweaking Agonist Efficacy at N-Methyl-d-aspartate Receptors by Site-Directed Mutagenesis
      Kasper B. Hansen, Rasmus P. Clausen, Esben J. Bjerrum, Christian Bechmann, Jeremy R. Greenwood, Caspar Christensen, Jesper L. Kristensen, Jan Egebjerg and Hans Bräuner-Osborne
      Molecular Pharmacology December 2005, 68 (6) 1510-1523; DOI: https://doi.org/10.1124/mol.105.014795

  2. Ellis, John

    1. Atypical Muscarinic Allosteric Modulation: Cooperativity between Modulators and Their Atypical Binding Topology in Muscarinic M2 and M2/M5 Chimeric Receptors
      Christian Tränkle, Andreas Dittmann, Uwe Schulz, Oliver Weyand, Stefan Buller, Kirstin Jöhren, Eberhard Heller, Nigel J. M. Birdsall, Ulrike Holzgrabe, John Ellis, Hans Dieter Höltje and Klaus Mohr
      Molecular Pharmacology December 2005, 68 (6) 1597-1610; DOI: https://doi.org/10.1124/mol.105.017707

  3. Enomoto, Takeshi

    1. Long-Lasting Impairment of Associative Learning Is Correlated with a Dysfunction of N-Methyl-d-aspartate-Extracellular Signaling-Regulated Kinase Signaling in Mice after Withdrawal from Repeated Administration of Phencyclidine
      Takeshi Enomoto, Yukihiro Noda, Akihiro Mouri, Eun-Joo Shin, Dayong Wang, Rina Murai, Kazuo Hotta, Hiroshi Furukawa, Atsumi Nitta, Hyoung-Chun Kim and Toshitaka Nabeshima
      Molecular Pharmacology December 2005, 68 (6) 1765-1774; DOI: https://doi.org/10.1124/mol.105.011304

  4. Erb, Christina

    1. Characterization of the First Potent and Selective PDE9 Inhibitor Using a cGMP Reporter Cell Line
      Frank Wunder, Adrian Tersteegen, Annegret Rebmann, Christina Erb, Thomas Fahrig and Martin Hendrix
      Molecular Pharmacology December 2005, 68 (6) 1775-1781; DOI: https://doi.org/10.1124/mol.105.017608

  5. e Silva, Raquel Lima

    1. Vascular Targeting of Ocular Neovascularization with a Vascular Endothelial Growth Factor121/Gelonin Chimeric Protein
      Hideo Akiyama, Khalid A. Mohamedali, Raquel Lima e Silva, Shu Kachi, JiKui Shen, Christina Hatara, Naoyasu Umeda, Sean F. Hackett, Sadia Aslam, Melissa Krause, Hong Lai, Michael G. Rosenblum and Peter A. Campochiaro
      Molecular Pharmacology December 2005, 68 (6) 1543-1550; DOI: https://doi.org/10.1124/mol.105.015628

  6. Evans, Christopher J.

    1. Induction of δ Opioid Receptor Function by Up-Regulation of Membrane Receptors in Mouse Primary Afferent Neurons
      Wendy Walwyn, Nigel T. Maidment, Matthew Sanders, Christopher J. Evans, Brigitte L. Kieffer and Tim G. Hales
      Molecular Pharmacology December 2005, 68 (6) 1688-1698; DOI: https://doi.org/10.1124/mol.105.014829

F

  1. Fahrig, Thomas

    1. Characterization of the First Potent and Selective PDE9 Inhibitor Using a cGMP Reporter Cell Line
      Frank Wunder, Adrian Tersteegen, Annegret Rebmann, Christina Erb, Thomas Fahrig and Martin Hendrix
      Molecular Pharmacology December 2005, 68 (6) 1775-1781; DOI: https://doi.org/10.1124/mol.105.017608

  2. Flatten, Karen S.

    1. Gemcitabine-Induced Activation of Checkpoint Signaling Pathways That Affect Tumor Cell Survival
      Larry M. Karnitz, Karen S. Flatten, Jill M. Wagner, David Loegering, Jennifer S. Hackbarth, Sonnet J. H. Arlander, Benjamin T. Vroman, M. Bijoy Thomas, Yong-Un Baek, Kevin M. Hopkins, Howard B. Lieberman, Junjie Chen, William A. Cliby and Scott H. Kaufmann
      Molecular Pharmacology December 2005, 68 (6) 1636-1644; DOI: https://doi.org/10.1124/mol.105.012716

  3. Foster, Caleb

    1. Redox Regulation of Cdc25B by Cell-Active Quinolinediones
      Marni Brisson, Theresa Nguyen, Peter Wipf, Beomjun Joo, Billy W. Day, John S. Skoko, Emanuel M. Schreiber, Caleb Foster, Pallavi Bansal and John S. Lazo
      Molecular Pharmacology December 2005, 68 (6) 1810-1820; DOI: https://doi.org/10.1124/mol.105.016360

  4. Fournier, Donna J.

    1. (-)-7′-Isothiocyanato-11-hydroxy-1′,1′-dimethylheptylhexahydrocannabinol (AM841), a High-Affinity Electrophilic Ligand, Interacts Covalently with a Cysteine in Helix Six and Activates the CB1 Cannabinoid Receptor
      Robert P. Picone, Atmaram D. Khanolkar, Wei Xu, Lionel A. Ayotte, Ganesh A. Thakur, Dow P. Hurst, Mary E. Abood, Patricia H. Reggio, Donna J. Fournier and Alexandros Makriyannis
      Molecular Pharmacology December 2005, 68 (6) 1623-1635; DOI: https://doi.org/10.1124/mol.105.014407

  5. Fozzard, Harry A.

    1. Molecular Modeling of Local Anesthetic Drug Binding by Voltage-Gated Sodium Channels
      Gregory M. Lipkind and Harry A. Fozzard
      Molecular Pharmacology December 2005, 68 (6) 1611-1622; DOI: https://doi.org/10.1124/mol.105.014803

  6. Fu, Xueyan

    1. Sulfated Polymannuroguluronate, a Novel Anti-AIDS Drug Candidate, Inhibits T Cell Apoptosis by Combating Oxidative Damage of Mitochondria
      Benchun Miao, Jing Li, Xueyan Fu, Li Gan, Xianliang Xin and Meiyu Geng
      Molecular Pharmacology December 2005, 68 (6) 1716-1727; DOI: https://doi.org/10.1124/mol.105.015412

  7. Furukawa, Hiroshi

    1. Long-Lasting Impairment of Associative Learning Is Correlated with a Dysfunction of N-Methyl-d-aspartate-Extracellular Signaling-Regulated Kinase Signaling in Mice after Withdrawal from Repeated Administration of Phencyclidine
      Takeshi Enomoto, Yukihiro Noda, Akihiro Mouri, Eun-Joo Shin, Dayong Wang, Rina Murai, Kazuo Hotta, Hiroshi Furukawa, Atsumi Nitta, Hyoung-Chun Kim and Toshitaka Nabeshima
      Molecular Pharmacology December 2005, 68 (6) 1765-1774; DOI: https://doi.org/10.1124/mol.105.011304

G

  1. Gago, Federico

    1. DNA Structural Similarity in the 2:1 Complexes of the Antitumor Drugs Trabectedin (Yondelis) and Chromomycin A3 with an Oligonucleotide Sequence Containing Two Adjacent TGG Binding Sites on Opposing Strands
      Esther Marco and Federico Gago
      Molecular Pharmacology December 2005, 68 (6) 1559-1567; DOI: https://doi.org/10.1124/mol.105.015685

  2. Galietta, Luis J. V.

    1. Antihypertensive 1,4-Dihydropyridines as Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator Channel Gating Defect Caused by Cystic Fibrosis Mutations
      Nicoletta Pedemonte, Tullia Diena, Emanuela Caci, Erika Nieddu, Mauro Mazzei, Roberto Ravazzolo, Olga Zegarra-Moran and Luis J. V. Galietta
      Molecular Pharmacology December 2005, 68 (6) 1736-1746; DOI: https://doi.org/10.1124/mol.105.015149

  3. Gan, Li

    1. Sulfated Polymannuroguluronate, a Novel Anti-AIDS Drug Candidate, Inhibits T Cell Apoptosis by Combating Oxidative Damage of Mitochondria
      Benchun Miao, Jing Li, Xueyan Fu, Li Gan, Xianliang Xin and Meiyu Geng
      Molecular Pharmacology December 2005, 68 (6) 1716-1727; DOI: https://doi.org/10.1124/mol.105.015412

  4. Gavva, Narender R.

    1. Proton Activation Does Not Alter Antagonist Interaction with the Capsaicin-Binding Pocket of TRPV1
      Narender R. Gavva, Rami Tamir, Lana Klionsky, Mark H. Norman, Jean-Claude Louis, Kenneth D. Wild and James J. S. Treanor
      Molecular Pharmacology December 2005, 68 (6) 1524-1533; DOI: https://doi.org/10.1124/mol.105.015727

  5. Geng, Meiyu

    1. Sulfated Polymannuroguluronate, a Novel Anti-AIDS Drug Candidate, Inhibits T Cell Apoptosis by Combating Oxidative Damage of Mitochondria
      Benchun Miao, Jing Li, Xueyan Fu, Li Gan, Xianliang Xin and Meiyu Geng
      Molecular Pharmacology December 2005, 68 (6) 1716-1727; DOI: https://doi.org/10.1124/mol.105.015412

  6. Gerber, Susana

    1. Mutations of a Conserved Lysine Residue in the N-Terminal Domain of α7 Nicotinic Receptors Affect Gating and Binding of Nicotinic Agonists
      Manuel Criado, José Mulet, José A. Bernal, Susana Gerber, Salvador Sala and Francisco Sala
      Molecular Pharmacology December 2005, 68 (6) 1669-1677; DOI: https://doi.org/10.1124/mol.105.015446

  7. Grassi, Francesca

    1. An α7 Nicotinic Acetylcholine Receptor Gain-of-Function Mutant That Retains Pharmacological Fidelity
      Andon N. Placzek, Francesca Grassi, Edwin M Meyer and Roger L. Papke
      Molecular Pharmacology December 2005, 68 (6) 1863-1876; DOI: https://doi.org/10.1124/mol.105.016402

  8. Gray, Miranda D.

    1. Activation of the Unfolded Protein Response Is Necessary and Sufficient for Reducing Topoisomerase IIα Protein Levels and Decreasing Sensitivity to Topoisomerase-Targeted Drugs
      Miranda D. Gray, Melissa Mann, John L. Nitiss and Linda M. Hendershot
      Molecular Pharmacology December 2005, 68 (6) 1699-1707; DOI: https://doi.org/10.1124/mol.105.014753

  9. Greenwood, Jeremy R.

    1. Tweaking Agonist Efficacy at N-Methyl-d-aspartate Receptors by Site-Directed Mutagenesis
      Kasper B. Hansen, Rasmus P. Clausen, Esben J. Bjerrum, Christian Bechmann, Jeremy R. Greenwood, Caspar Christensen, Jesper L. Kristensen, Jan Egebjerg and Hans Bräuner-Osborne
      Molecular Pharmacology December 2005, 68 (6) 1510-1523; DOI: https://doi.org/10.1124/mol.105.014795

  10. Gyamfi, Maxwell A.

    1. Retinoid X Receptor α Regulates the Expression of Glutathione S-transferase Genes and Modulates Acetaminophen-Glutathione Conjugation in Mouse Liver
      Guoli Dai, Nathan Chou, Lin He, Maxwell A. Gyamfi, Alphonse J. Mendy, Angela L. Slitt, Curtis D. Klaassen and Yu-Jui Y. Wan
      Molecular Pharmacology December 2005, 68 (6) 1590-1596; DOI: https://doi.org/10.1124/mol.105.013680

H

  1. Hackbarth, Jennifer S.

    1. Gemcitabine-Induced Activation of Checkpoint Signaling Pathways That Affect Tumor Cell Survival
      Larry M. Karnitz, Karen S. Flatten, Jill M. Wagner, David Loegering, Jennifer S. Hackbarth, Sonnet J. H. Arlander, Benjamin T. Vroman, M. Bijoy Thomas, Yong-Un Baek, Kevin M. Hopkins, Howard B. Lieberman, Junjie Chen, William A. Cliby and Scott H. Kaufmann
      Molecular Pharmacology December 2005, 68 (6) 1636-1644; DOI: https://doi.org/10.1124/mol.105.012716

  2. Hackett, Sean F.

    1. Vascular Targeting of Ocular Neovascularization with a Vascular Endothelial Growth Factor121/Gelonin Chimeric Protein
      Hideo Akiyama, Khalid A. Mohamedali, Raquel Lima e Silva, Shu Kachi, JiKui Shen, Christina Hatara, Naoyasu Umeda, Sean F. Hackett, Sadia Aslam, Melissa Krause, Hong Lai, Michael G. Rosenblum and Peter A. Campochiaro
      Molecular Pharmacology December 2005, 68 (6) 1543-1550; DOI: https://doi.org/10.1124/mol.105.015628

  3. Hales, Tim G.

    1. Induction of δ Opioid Receptor Function by Up-Regulation of Membrane Receptors in Mouse Primary Afferent Neurons
      Wendy Walwyn, Nigel T. Maidment, Matthew Sanders, Christopher J. Evans, Brigitte L. Kieffer and Tim G. Hales
      Molecular Pharmacology December 2005, 68 (6) 1688-1698; DOI: https://doi.org/10.1124/mol.105.014829

  4. Hansen, Kasper B.

    1. Tweaking Agonist Efficacy at N-Methyl-d-aspartate Receptors by Site-Directed Mutagenesis
      Kasper B. Hansen, Rasmus P. Clausen, Esben J. Bjerrum, Christian Bechmann, Jeremy R. Greenwood, Caspar Christensen, Jesper L. Kristensen, Jan Egebjerg and Hans Bräuner-Osborne
      Molecular Pharmacology December 2005, 68 (6) 1510-1523; DOI: https://doi.org/10.1124/mol.105.014795

  5. Hatara, Christina

    1. Vascular Targeting of Ocular Neovascularization with a Vascular Endothelial Growth Factor121/Gelonin Chimeric Protein
      Hideo Akiyama, Khalid A. Mohamedali, Raquel Lima e Silva, Shu Kachi, JiKui Shen, Christina Hatara, Naoyasu Umeda, Sean F. Hackett, Sadia Aslam, Melissa Krause, Hong Lai, Michael G. Rosenblum and Peter A. Campochiaro
      Molecular Pharmacology December 2005, 68 (6) 1543-1550; DOI: https://doi.org/10.1124/mol.105.015628

  6. He, Lin

    1. Retinoid X Receptor α Regulates the Expression of Glutathione S-transferase Genes and Modulates Acetaminophen-Glutathione Conjugation in Mouse Liver
      Guoli Dai, Nathan Chou, Lin He, Maxwell A. Gyamfi, Alphonse J. Mendy, Angela L. Slitt, Curtis D. Klaassen and Yu-Jui Y. Wan
      Molecular Pharmacology December 2005, 68 (6) 1590-1596; DOI: https://doi.org/10.1124/mol.105.013680

  7. Heald, Robert A.

    1. Pharmacodynamics of the G-Quadruplex-Stabilizing Telomerase Inhibitor 3,11-Difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in Vitro: Activity in Human Tumor Cells Correlates with Telomere Length and Can Be Enhanced, or Antagonized, with Cytotoxic Agents
      Jennifer C. Cookson, Fangping Dai, Victoria Smith, Robert A. Heald, Charles A. Laughton, Malcolm F. G. Stevens and Angelika M. Burger
      Molecular Pharmacology December 2005, 68 (6) 1551-1558; DOI: https://doi.org/10.1124/mol.105.013300

  8. Hébert, Elise

    1. Opposite Effects of Histone Deacetylase Inhibitors on Glucocorticoid and Estrogen Signaling in Human Endometrial Ishikawa Cells
      Walter Rocha, Rocio Sanchez, Julie Deschênes, Anick Auger, Elise Hébert, John H. White and Sylvie Mader
      Molecular Pharmacology December 2005, 68 (6) 1852-1862; DOI: https://doi.org/10.1124/mol.105.014514

  9. Heller, Eberhard

    1. Atypical Muscarinic Allosteric Modulation: Cooperativity between Modulators and Their Atypical Binding Topology in Muscarinic M2 and M2/M5 Chimeric Receptors
      Christian Tränkle, Andreas Dittmann, Uwe Schulz, Oliver Weyand, Stefan Buller, Kirstin Jöhren, Eberhard Heller, Nigel J. M. Birdsall, Ulrike Holzgrabe, John Ellis, Hans Dieter Höltje and Klaus Mohr
      Molecular Pharmacology December 2005, 68 (6) 1597-1610; DOI: https://doi.org/10.1124/mol.105.017707

  10. Hendershot, Linda M.

    1. Activation of the Unfolded Protein Response Is Necessary and Sufficient for Reducing Topoisomerase IIα Protein Levels and Decreasing Sensitivity to Topoisomerase-Targeted Drugs
      Miranda D. Gray, Melissa Mann, John L. Nitiss and Linda M. Hendershot
      Molecular Pharmacology December 2005, 68 (6) 1699-1707; DOI: https://doi.org/10.1124/mol.105.014753

  11. Hendrix, Martin

    1. Characterization of the First Potent and Selective PDE9 Inhibitor Using a cGMP Reporter Cell Line
      Frank Wunder, Adrian Tersteegen, Annegret Rebmann, Christina Erb, Thomas Fahrig and Martin Hendrix
      Molecular Pharmacology December 2005, 68 (6) 1775-1781; DOI: https://doi.org/10.1124/mol.105.017608

  12. Höltje, Hans Dieter

    1. Atypical Muscarinic Allosteric Modulation: Cooperativity between Modulators and Their Atypical Binding Topology in Muscarinic M2 and M2/M5 Chimeric Receptors
      Christian Tränkle, Andreas Dittmann, Uwe Schulz, Oliver Weyand, Stefan Buller, Kirstin Jöhren, Eberhard Heller, Nigel J. M. Birdsall, Ulrike Holzgrabe, John Ellis, Hans Dieter Höltje and Klaus Mohr
      Molecular Pharmacology December 2005, 68 (6) 1597-1610; DOI: https://doi.org/10.1124/mol.105.017707

  13. Holzgrabe, Ulrike

    1. Atypical Muscarinic Allosteric Modulation: Cooperativity between Modulators and Their Atypical Binding Topology in Muscarinic M2 and M2/M5 Chimeric Receptors
      Christian Tränkle, Andreas Dittmann, Uwe Schulz, Oliver Weyand, Stefan Buller, Kirstin Jöhren, Eberhard Heller, Nigel J. M. Birdsall, Ulrike Holzgrabe, John Ellis, Hans Dieter Höltje and Klaus Mohr
      Molecular Pharmacology December 2005, 68 (6) 1597-1610; DOI: https://doi.org/10.1124/mol.105.017707

  14. Hopkins, Kevin M.

    1. Gemcitabine-Induced Activation of Checkpoint Signaling Pathways That Affect Tumor Cell Survival
      Larry M. Karnitz, Karen S. Flatten, Jill M. Wagner, David Loegering, Jennifer S. Hackbarth, Sonnet J. H. Arlander, Benjamin T. Vroman, M. Bijoy Thomas, Yong-Un Baek, Kevin M. Hopkins, Howard B. Lieberman, Junjie Chen, William A. Cliby and Scott H. Kaufmann
      Molecular Pharmacology December 2005, 68 (6) 1636-1644; DOI: https://doi.org/10.1124/mol.105.012716

  15. Hotta, Kazuo

    1. Long-Lasting Impairment of Associative Learning Is Correlated with a Dysfunction of N-Methyl-d-aspartate-Extracellular Signaling-Regulated Kinase Signaling in Mice after Withdrawal from Repeated Administration of Phencyclidine
      Takeshi Enomoto, Yukihiro Noda, Akihiro Mouri, Eun-Joo Shin, Dayong Wang, Rina Murai, Kazuo Hotta, Hiroshi Furukawa, Atsumi Nitta, Hyoung-Chun Kim and Toshitaka Nabeshima
      Molecular Pharmacology December 2005, 68 (6) 1765-1774; DOI: https://doi.org/10.1124/mol.105.011304

  16. Hu, Lihong

    1. Stereospecific Induction of Nuclear Factor-κB Activation by Isochamaejasmin
      Qinghai Tian, Jing Li, Xin Xie, Meiling Sun, Hairong Sang, Caihong Zhou, Tianying An, Lihong Hu, Richard D. Ye and Ming-Wei Wang
      Molecular Pharmacology December 2005, 68 (6) 1534-1542; DOI: https://doi.org/10.1124/mol.105.014720

  17. Hurst, Dow P.

    1. (-)-7′-Isothiocyanato-11-hydroxy-1′,1′-dimethylheptylhexahydrocannabinol (AM841), a High-Affinity Electrophilic Ligand, Interacts Covalently with a Cysteine in Helix Six and Activates the CB1 Cannabinoid Receptor
      Robert P. Picone, Atmaram D. Khanolkar, Wei Xu, Lionel A. Ayotte, Ganesh A. Thakur, Dow P. Hurst, Mary E. Abood, Patricia H. Reggio, Donna J. Fournier and Alexandros Makriyannis
      Molecular Pharmacology December 2005, 68 (6) 1623-1635; DOI: https://doi.org/10.1124/mol.105.014407

I

  1. Insel, Paul A.

    1. Editor's Note
      Paul A. Insel
      Molecular Pharmacology December 2005, 68 (6) 1505; DOI: https://doi.org/10.1124/mol.68.6.1505

J

  1. Jin, Sun Mi

    1. Involvement of IL-10 in Peroxisome Proliferator-Activated Receptor γ-Mediated Anti-Inflammatory Response in Asthma
      So Ri Kim, Kyung Sun Lee, Hee Sun Park, Seoung Ju Park, Kyung Hoon Min, Sun Mi Jin and Yong Chul Lee
      Molecular Pharmacology December 2005, 68 (6) 1568-1575; DOI: https://doi.org/10.1124/mol.105.017160

  2. Jöhren, Kirstin

    1. Atypical Muscarinic Allosteric Modulation: Cooperativity between Modulators and Their Atypical Binding Topology in Muscarinic M2 and M2/M5 Chimeric Receptors
      Christian Tränkle, Andreas Dittmann, Uwe Schulz, Oliver Weyand, Stefan Buller, Kirstin Jöhren, Eberhard Heller, Nigel J. M. Birdsall, Ulrike Holzgrabe, John Ellis, Hans Dieter Höltje and Klaus Mohr
      Molecular Pharmacology December 2005, 68 (6) 1597-1610; DOI: https://doi.org/10.1124/mol.105.017707

  3. Joo, Beomjun

    1. Redox Regulation of Cdc25B by Cell-Active Quinolinediones
      Marni Brisson, Theresa Nguyen, Peter Wipf, Beomjun Joo, Billy W. Day, John S. Skoko, Emanuel M. Schreiber, Caleb Foster, Pallavi Bansal and John S. Lazo
      Molecular Pharmacology December 2005, 68 (6) 1810-1820; DOI: https://doi.org/10.1124/mol.105.016360

K

  1. Kachi, Shu

    1. Vascular Targeting of Ocular Neovascularization with a Vascular Endothelial Growth Factor121/Gelonin Chimeric Protein
      Hideo Akiyama, Khalid A. Mohamedali, Raquel Lima e Silva, Shu Kachi, JiKui Shen, Christina Hatara, Naoyasu Umeda, Sean F. Hackett, Sadia Aslam, Melissa Krause, Hong Lai, Michael G. Rosenblum and Peter A. Campochiaro
      Molecular Pharmacology December 2005, 68 (6) 1543-1550; DOI: https://doi.org/10.1124/mol.105.015628

  2. Kang, ChulHee

    1. Effects of Drugs with Muscle-Related Side Effects and Affinity for Calsequestrin on the Calcium Regulatory Function of Sarcoplasmic Reticulum Microsomes
      EunJung Kim, Maggie Tam, William F. Siems and ChulHee Kang
      Molecular Pharmacology December 2005, 68 (6) 1708-1715; DOI: https://doi.org/10.1124/mol.105.016253

  3. Karnitz, Larry M.

    1. Gemcitabine-Induced Activation of Checkpoint Signaling Pathways That Affect Tumor Cell Survival
      Larry M. Karnitz, Karen S. Flatten, Jill M. Wagner, David Loegering, Jennifer S. Hackbarth, Sonnet J. H. Arlander, Benjamin T. Vroman, M. Bijoy Thomas, Yong-Un Baek, Kevin M. Hopkins, Howard B. Lieberman, Junjie Chen, William A. Cliby and Scott H. Kaufmann
      Molecular Pharmacology December 2005, 68 (6) 1636-1644; DOI: https://doi.org/10.1124/mol.105.012716

  4. Kaufmann, Scott H.

    1. Gemcitabine-Induced Activation of Checkpoint Signaling Pathways That Affect Tumor Cell Survival
      Larry M. Karnitz, Karen S. Flatten, Jill M. Wagner, David Loegering, Jennifer S. Hackbarth, Sonnet J. H. Arlander, Benjamin T. Vroman, M. Bijoy Thomas, Yong-Un Baek, Kevin M. Hopkins, Howard B. Lieberman, Junjie Chen, William A. Cliby and Scott H. Kaufmann
      Molecular Pharmacology December 2005, 68 (6) 1636-1644; DOI: https://doi.org/10.1124/mol.105.012716

  5. Kellar, Kenneth J.

    1. Nicotinic Cholinergic Receptors in the Rat Retina: Simple and Mixed Heteromeric Subtypes
      Andrea M. Marritt, Brandon C. Cox, Robert P. Yasuda, J. Michael McIntosh, Yingxian Xiao, Barry B. Wolfe and Kenneth J. Kellar
      Molecular Pharmacology December 2005, 68 (6) 1656-1668; DOI: https://doi.org/10.1124/mol.105.012369

  6. Khanolkar, Atmaram D.

    1. (-)-7′-Isothiocyanato-11-hydroxy-1′,1′-dimethylheptylhexahydrocannabinol (AM841), a High-Affinity Electrophilic Ligand, Interacts Covalently with a Cysteine in Helix Six and Activates the CB1 Cannabinoid Receptor
      Robert P. Picone, Atmaram D. Khanolkar, Wei Xu, Lionel A. Ayotte, Ganesh A. Thakur, Dow P. Hurst, Mary E. Abood, Patricia H. Reggio, Donna J. Fournier and Alexandros Makriyannis
      Molecular Pharmacology December 2005, 68 (6) 1623-1635; DOI: https://doi.org/10.1124/mol.105.014407

  7. Kieffer, Brigitte L.

    1. Induction of δ Opioid Receptor Function by Up-Regulation of Membrane Receptors in Mouse Primary Afferent Neurons
      Wendy Walwyn, Nigel T. Maidment, Matthew Sanders, Christopher J. Evans, Brigitte L. Kieffer and Tim G. Hales
      Molecular Pharmacology December 2005, 68 (6) 1688-1698; DOI: https://doi.org/10.1124/mol.105.014829

  8. Kim, EunJung

    1. Effects of Drugs with Muscle-Related Side Effects and Affinity for Calsequestrin on the Calcium Regulatory Function of Sarcoplasmic Reticulum Microsomes
      EunJung Kim, Maggie Tam, William F. Siems and ChulHee Kang
      Molecular Pharmacology December 2005, 68 (6) 1708-1715; DOI: https://doi.org/10.1124/mol.105.016253

  9. Kim, Hyoung-Chun

    1. Long-Lasting Impairment of Associative Learning Is Correlated with a Dysfunction of N-Methyl-d-aspartate-Extracellular Signaling-Regulated Kinase Signaling in Mice after Withdrawal from Repeated Administration of Phencyclidine
      Takeshi Enomoto, Yukihiro Noda, Akihiro Mouri, Eun-Joo Shin, Dayong Wang, Rina Murai, Kazuo Hotta, Hiroshi Furukawa, Atsumi Nitta, Hyoung-Chun Kim and Toshitaka Nabeshima
      Molecular Pharmacology December 2005, 68 (6) 1765-1774; DOI: https://doi.org/10.1124/mol.105.011304

  10. Kim, Ji-Hyun

    1. Inhibition of the Catalytic Activity of Hypoxia-Inducible Factor-1α-Prolyl-Hydroxylase 2 by a MYND-Type Zinc Finger
      Kyung-Ok Choi, Taekyong Lee, Naery Lee, Ji-Hyun Kim, Eun Gyeong Yang, Jung Min Yoon, Jin Hwan Kim, Tae Gyu Lee and Hyunsung Park
      Molecular Pharmacology December 2005, 68 (6) 1803-1809; DOI: https://doi.org/10.1124/mol.105.015271

  11. Kim, Jin Hwan

    1. Inhibition of the Catalytic Activity of Hypoxia-Inducible Factor-1α-Prolyl-Hydroxylase 2 by a MYND-Type Zinc Finger
      Kyung-Ok Choi, Taekyong Lee, Naery Lee, Ji-Hyun Kim, Eun Gyeong Yang, Jung Min Yoon, Jin Hwan Kim, Tae Gyu Lee and Hyunsung Park
      Molecular Pharmacology December 2005, 68 (6) 1803-1809; DOI: https://doi.org/10.1124/mol.105.015271

  12. Kim, So Ri

    1. Involvement of IL-10 in Peroxisome Proliferator-Activated Receptor γ-Mediated Anti-Inflammatory Response in Asthma
      So Ri Kim, Kyung Sun Lee, Hee Sun Park, Seoung Ju Park, Kyung Hoon Min, Sun Mi Jin and Yong Chul Lee
      Molecular Pharmacology December 2005, 68 (6) 1568-1575; DOI: https://doi.org/10.1124/mol.105.017160

  13. Klaassen, Curtis D.

    1. Retinoid X Receptor α Regulates the Expression of Glutathione S-transferase Genes and Modulates Acetaminophen-Glutathione Conjugation in Mouse Liver
      Guoli Dai, Nathan Chou, Lin He, Maxwell A. Gyamfi, Alphonse J. Mendy, Angela L. Slitt, Curtis D. Klaassen and Yu-Jui Y. Wan
      Molecular Pharmacology December 2005, 68 (6) 1590-1596; DOI: https://doi.org/10.1124/mol.105.013680

  14. Klionsky, Lana

    1. Proton Activation Does Not Alter Antagonist Interaction with the Capsaicin-Binding Pocket of TRPV1
      Narender R. Gavva, Rami Tamir, Lana Klionsky, Mark H. Norman, Jean-Claude Louis, Kenneth D. Wild and James J. S. Treanor
      Molecular Pharmacology December 2005, 68 (6) 1524-1533; DOI: https://doi.org/10.1124/mol.105.015727

  15. Krause, Melissa

    1. Vascular Targeting of Ocular Neovascularization with a Vascular Endothelial Growth Factor121/Gelonin Chimeric Protein
      Hideo Akiyama, Khalid A. Mohamedali, Raquel Lima e Silva, Shu Kachi, JiKui Shen, Christina Hatara, Naoyasu Umeda, Sean F. Hackett, Sadia Aslam, Melissa Krause, Hong Lai, Michael G. Rosenblum and Peter A. Campochiaro
      Molecular Pharmacology December 2005, 68 (6) 1543-1550; DOI: https://doi.org/10.1124/mol.105.015628

  16. Krause, Stephan

    1. Identification and Selective Inhibition of the Channel Mode of the Neuronal GABA Transporter 1
      Stephan Krause and Wolfgang Schwarz
      Molecular Pharmacology December 2005, 68 (6) 1728-1735; DOI: https://doi.org/10.1124/mol.105.013870

  17. Kristensen, Jesper L.

    1. Tweaking Agonist Efficacy at N-Methyl-d-aspartate Receptors by Site-Directed Mutagenesis
      Kasper B. Hansen, Rasmus P. Clausen, Esben J. Bjerrum, Christian Bechmann, Jeremy R. Greenwood, Caspar Christensen, Jesper L. Kristensen, Jan Egebjerg and Hans Bräuner-Osborne
      Molecular Pharmacology December 2005, 68 (6) 1510-1523; DOI: https://doi.org/10.1124/mol.105.014795

  18. Kuryatov, A.

    1. Nicotine Acts as a Pharmacological Chaperone to Up-Regulate Human α4β2 Acetylcholine Receptors
      A. Kuryatov, J. Luo, J. Cooper and J. Lindstrom
      Molecular Pharmacology December 2005, 68 (6) 1839-1851; DOI: https://doi.org/10.1124/mol.105.012419

L

  1. Lai, Hong

    1. Vascular Targeting of Ocular Neovascularization with a Vascular Endothelial Growth Factor121/Gelonin Chimeric Protein
      Hideo Akiyama, Khalid A. Mohamedali, Raquel Lima e Silva, Shu Kachi, JiKui Shen, Christina Hatara, Naoyasu Umeda, Sean F. Hackett, Sadia Aslam, Melissa Krause, Hong Lai, Michael G. Rosenblum and Peter A. Campochiaro
      Molecular Pharmacology December 2005, 68 (6) 1543-1550; DOI: https://doi.org/10.1124/mol.105.015628

  2. Laughton, Charles A.

    1. Pharmacodynamics of the G-Quadruplex-Stabilizing Telomerase Inhibitor 3,11-Difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in Vitro: Activity in Human Tumor Cells Correlates with Telomere Length and Can Be Enhanced, or Antagonized, with Cytotoxic Agents
      Jennifer C. Cookson, Fangping Dai, Victoria Smith, Robert A. Heald, Charles A. Laughton, Malcolm F. G. Stevens and Angelika M. Burger
      Molecular Pharmacology December 2005, 68 (6) 1551-1558; DOI: https://doi.org/10.1124/mol.105.013300

  3. Lazo, John S.

    1. Redox Regulation of Cdc25B by Cell-Active Quinolinediones
      Marni Brisson, Theresa Nguyen, Peter Wipf, Beomjun Joo, Billy W. Day, John S. Skoko, Emanuel M. Schreiber, Caleb Foster, Pallavi Bansal and John S. Lazo
      Molecular Pharmacology December 2005, 68 (6) 1810-1820; DOI: https://doi.org/10.1124/mol.105.016360

  4. Lee, Kyung Sun

    1. Involvement of IL-10 in Peroxisome Proliferator-Activated Receptor γ-Mediated Anti-Inflammatory Response in Asthma
      So Ri Kim, Kyung Sun Lee, Hee Sun Park, Seoung Ju Park, Kyung Hoon Min, Sun Mi Jin and Yong Chul Lee
      Molecular Pharmacology December 2005, 68 (6) 1568-1575; DOI: https://doi.org/10.1124/mol.105.017160

  5. Lee, Naery

    1. Inhibition of the Catalytic Activity of Hypoxia-Inducible Factor-1α-Prolyl-Hydroxylase 2 by a MYND-Type Zinc Finger
      Kyung-Ok Choi, Taekyong Lee, Naery Lee, Ji-Hyun Kim, Eun Gyeong Yang, Jung Min Yoon, Jin Hwan Kim, Tae Gyu Lee and Hyunsung Park
      Molecular Pharmacology December 2005, 68 (6) 1803-1809; DOI: https://doi.org/10.1124/mol.105.015271

  6. Lee, Tae Gyu

    1. Inhibition of the Catalytic Activity of Hypoxia-Inducible Factor-1α-Prolyl-Hydroxylase 2 by a MYND-Type Zinc Finger
      Kyung-Ok Choi, Taekyong Lee, Naery Lee, Ji-Hyun Kim, Eun Gyeong Yang, Jung Min Yoon, Jin Hwan Kim, Tae Gyu Lee and Hyunsung Park
      Molecular Pharmacology December 2005, 68 (6) 1803-1809; DOI: https://doi.org/10.1124/mol.105.015271

  7. Lee, Taekyong

    1. Inhibition of the Catalytic Activity of Hypoxia-Inducible Factor-1α-Prolyl-Hydroxylase 2 by a MYND-Type Zinc Finger
      Kyung-Ok Choi, Taekyong Lee, Naery Lee, Ji-Hyun Kim, Eun Gyeong Yang, Jung Min Yoon, Jin Hwan Kim, Tae Gyu Lee and Hyunsung Park
      Molecular Pharmacology December 2005, 68 (6) 1803-1809; DOI: https://doi.org/10.1124/mol.105.015271

  8. Lee, Yong Chul

    1. Involvement of IL-10 in Peroxisome Proliferator-Activated Receptor γ-Mediated Anti-Inflammatory Response in Asthma
      So Ri Kim, Kyung Sun Lee, Hee Sun Park, Seoung Ju Park, Kyung Hoon Min, Sun Mi Jin and Yong Chul Lee
      Molecular Pharmacology December 2005, 68 (6) 1568-1575; DOI: https://doi.org/10.1124/mol.105.017160

  9. Li, Jing

    1. Stereospecific Induction of Nuclear Factor-κB Activation by Isochamaejasmin
      Qinghai Tian, Jing Li, Xin Xie, Meiling Sun, Hairong Sang, Caihong Zhou, Tianying An, Lihong Hu, Richard D. Ye and Ming-Wei Wang
      Molecular Pharmacology December 2005, 68 (6) 1534-1542; DOI: https://doi.org/10.1124/mol.105.014720
    2. Sulfated Polymannuroguluronate, a Novel Anti-AIDS Drug Candidate, Inhibits T Cell Apoptosis by Combating Oxidative Damage of Mitochondria
      Benchun Miao, Jing Li, Xueyan Fu, Li Gan, Xianliang Xin and Meiyu Geng
      Molecular Pharmacology December 2005, 68 (6) 1716-1727; DOI: https://doi.org/10.1124/mol.105.015412

  10. Liang, Wenbin

    1. Direct Stimulation of KATP Channels by Exogenous and Endogenous Hydrogen Sulfide in Vascular Smooth Muscle Cells
      Guanghua Tang, Lingyun Wu, Wenbin Liang and Rui Wang
      Molecular Pharmacology December 2005, 68 (6) 1757-1764; DOI: https://doi.org/10.1124/mol.105.017467

  11. Lieberman, Howard B.

    1. Gemcitabine-Induced Activation of Checkpoint Signaling Pathways That Affect Tumor Cell Survival
      Larry M. Karnitz, Karen S. Flatten, Jill M. Wagner, David Loegering, Jennifer S. Hackbarth, Sonnet J. H. Arlander, Benjamin T. Vroman, M. Bijoy Thomas, Yong-Un Baek, Kevin M. Hopkins, Howard B. Lieberman, Junjie Chen, William A. Cliby and Scott H. Kaufmann
      Molecular Pharmacology December 2005, 68 (6) 1636-1644; DOI: https://doi.org/10.1124/mol.105.012716

  12. Lindstrom, J.

    1. Nicotine Acts as a Pharmacological Chaperone to Up-Regulate Human α4β2 Acetylcholine Receptors
      A. Kuryatov, J. Luo, J. Cooper and J. Lindstrom
      Molecular Pharmacology December 2005, 68 (6) 1839-1851; DOI: https://doi.org/10.1124/mol.105.012419

  13. Lipkind, Gregory M.

    1. Molecular Modeling of Local Anesthetic Drug Binding by Voltage-Gated Sodium Channels
      Gregory M. Lipkind and Harry A. Fozzard
      Molecular Pharmacology December 2005, 68 (6) 1611-1622; DOI: https://doi.org/10.1124/mol.105.014803

  14. Liu, Shengxi

    1. 1,1-Bis(3′-indolyl)-1-(p-substitutedphenyl)methanes Are Peroxisome Proliferator-Activated Receptor γ Agonists but Decrease HCT-116 Colon Cancer Cell Survival through Receptor-Independent Activation of Early Growth Response-1 and Nonsteroidal Anti-Inflammatory Drug-Activated Gene-1
      Sudhakar Chintharlapalli, Sabitha Papineni, Seung Joon Baek, Shengxi Liu and Stephen Safe
      Molecular Pharmacology December 2005, 68 (6) 1782-1792; DOI: https://doi.org/10.1124/mol.105.017046

  15. Loegering, David

    1. Gemcitabine-Induced Activation of Checkpoint Signaling Pathways That Affect Tumor Cell Survival
      Larry M. Karnitz, Karen S. Flatten, Jill M. Wagner, David Loegering, Jennifer S. Hackbarth, Sonnet J. H. Arlander, Benjamin T. Vroman, M. Bijoy Thomas, Yong-Un Baek, Kevin M. Hopkins, Howard B. Lieberman, Junjie Chen, William A. Cliby and Scott H. Kaufmann
      Molecular Pharmacology December 2005, 68 (6) 1636-1644; DOI: https://doi.org/10.1124/mol.105.012716

  16. Louis, Jean-Claude

    1. Proton Activation Does Not Alter Antagonist Interaction with the Capsaicin-Binding Pocket of TRPV1
      Narender R. Gavva, Rami Tamir, Lana Klionsky, Mark H. Norman, Jean-Claude Louis, Kenneth D. Wild and James J. S. Treanor
      Molecular Pharmacology December 2005, 68 (6) 1524-1533; DOI: https://doi.org/10.1124/mol.105.015727

  17. Luo, J.

    1. Nicotine Acts as a Pharmacological Chaperone to Up-Regulate Human α4β2 Acetylcholine Receptors
      A. Kuryatov, J. Luo, J. Cooper and J. Lindstrom
      Molecular Pharmacology December 2005, 68 (6) 1839-1851; DOI: https://doi.org/10.1124/mol.105.012419

M

  1. Mader, Sylvie

    1. Opposite Effects of Histone Deacetylase Inhibitors on Glucocorticoid and Estrogen Signaling in Human Endometrial Ishikawa Cells
      Walter Rocha, Rocio Sanchez, Julie Deschênes, Anick Auger, Elise Hébert, John H. White and Sylvie Mader
      Molecular Pharmacology December 2005, 68 (6) 1852-1862; DOI: https://doi.org/10.1124/mol.105.014514

  2. Maidment, Nigel T.

    1. Induction of δ Opioid Receptor Function by Up-Regulation of Membrane Receptors in Mouse Primary Afferent Neurons
      Wendy Walwyn, Nigel T. Maidment, Matthew Sanders, Christopher J. Evans, Brigitte L. Kieffer and Tim G. Hales
      Molecular Pharmacology December 2005, 68 (6) 1688-1698; DOI: https://doi.org/10.1124/mol.105.014829

  3. Makriyannis, Alexandros

    1. (-)-7′-Isothiocyanato-11-hydroxy-1′,1′-dimethylheptylhexahydrocannabinol (AM841), a High-Affinity Electrophilic Ligand, Interacts Covalently with a Cysteine in Helix Six and Activates the CB1 Cannabinoid Receptor
      Robert P. Picone, Atmaram D. Khanolkar, Wei Xu, Lionel A. Ayotte, Ganesh A. Thakur, Dow P. Hurst, Mary E. Abood, Patricia H. Reggio, Donna J. Fournier and Alexandros Makriyannis
      Molecular Pharmacology December 2005, 68 (6) 1623-1635; DOI: https://doi.org/10.1124/mol.105.014407

  4. Mallory, Julia C.

    1. A Novel Group of Genes Regulates Susceptibility to Antineoplastic Drugs in Highly Tumorigenic Breast Cancer Cells
      Julia C. Mallory, Gerard Crudden, Amelia Oliva, Christopher Saunders, Arnold Stromberg and Rolf J. Craven
      Molecular Pharmacology December 2005, 68 (6) 1747-1756; DOI: https://doi.org/10.1124/mol.105.016519

  5. Mann, Melissa

    1. Activation of the Unfolded Protein Response Is Necessary and Sufficient for Reducing Topoisomerase IIα Protein Levels and Decreasing Sensitivity to Topoisomerase-Targeted Drugs
      Miranda D. Gray, Melissa Mann, John L. Nitiss and Linda M. Hendershot
      Molecular Pharmacology December 2005, 68 (6) 1699-1707; DOI: https://doi.org/10.1124/mol.105.014753

  6. Marceau, François

    1. N-Substituted 4-Aminobenzamides (Procainamide Analogs): An Assessment of Multiple Cellular Effects Concerning Ion Trapping
      Guillaume Morissette, Emmanuel Moreau, René C.-Gaudreault and François Marceau
      Molecular Pharmacology December 2005, 68 (6) 1576-1589; DOI: https://doi.org/10.1124/mol.105.016527

  7. Marco, Esther

    1. DNA Structural Similarity in the 2:1 Complexes of the Antitumor Drugs Trabectedin (Yondelis) and Chromomycin A3 with an Oligonucleotide Sequence Containing Two Adjacent TGG Binding Sites on Opposing Strands
      Esther Marco and Federico Gago
      Molecular Pharmacology December 2005, 68 (6) 1559-1567; DOI: https://doi.org/10.1124/mol.105.015685

  8. Marritt, Andrea M.

    1. Nicotinic Cholinergic Receptors in the Rat Retina: Simple and Mixed Heteromeric Subtypes
      Andrea M. Marritt, Brandon C. Cox, Robert P. Yasuda, J. Michael McIntosh, Yingxian Xiao, Barry B. Wolfe and Kenneth J. Kellar
      Molecular Pharmacology December 2005, 68 (6) 1656-1668; DOI: https://doi.org/10.1124/mol.105.012369

  9. Mazzei, Mauro

    1. Antihypertensive 1,4-Dihydropyridines as Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator Channel Gating Defect Caused by Cystic Fibrosis Mutations
      Nicoletta Pedemonte, Tullia Diena, Emanuela Caci, Erika Nieddu, Mauro Mazzei, Roberto Ravazzolo, Olga Zegarra-Moran and Luis J. V. Galietta
      Molecular Pharmacology December 2005, 68 (6) 1736-1746; DOI: https://doi.org/10.1124/mol.105.015149

  10. McIntosh, J. Michael

    1. Nicotinic Cholinergic Receptors in the Rat Retina: Simple and Mixed Heteromeric Subtypes
      Andrea M. Marritt, Brandon C. Cox, Robert P. Yasuda, J. Michael McIntosh, Yingxian Xiao, Barry B. Wolfe and Kenneth J. Kellar
      Molecular Pharmacology December 2005, 68 (6) 1656-1668; DOI: https://doi.org/10.1124/mol.105.012369

  11. Mendy, Alphonse J.

    1. Retinoid X Receptor α Regulates the Expression of Glutathione S-transferase Genes and Modulates Acetaminophen-Glutathione Conjugation in Mouse Liver
      Guoli Dai, Nathan Chou, Lin He, Maxwell A. Gyamfi, Alphonse J. Mendy, Angela L. Slitt, Curtis D. Klaassen and Yu-Jui Y. Wan
      Molecular Pharmacology December 2005, 68 (6) 1590-1596; DOI: https://doi.org/10.1124/mol.105.013680

  12. Meyer, Edwin M

    1. An α7 Nicotinic Acetylcholine Receptor Gain-of-Function Mutant That Retains Pharmacological Fidelity
      Andon N. Placzek, Francesca Grassi, Edwin M Meyer and Roger L. Papke
      Molecular Pharmacology December 2005, 68 (6) 1863-1876; DOI: https://doi.org/10.1124/mol.105.016402

  13. Miao, Benchun

    1. Sulfated Polymannuroguluronate, a Novel Anti-AIDS Drug Candidate, Inhibits T Cell Apoptosis by Combating Oxidative Damage of Mitochondria
      Benchun Miao, Jing Li, Xueyan Fu, Li Gan, Xianliang Xin and Meiyu Geng
      Molecular Pharmacology December 2005, 68 (6) 1716-1727; DOI: https://doi.org/10.1124/mol.105.015412

  14. Milligan, Graeme

    1. A Key Serine for the GTPase-Activating Protein Function of Regulator of G Protein Signaling Proteins Is Not a General Target for 14-3-3 Interactions
      Richard J. Ward and Graeme Milligan
      Molecular Pharmacology December 2005, 68 (6) 1821-1830; DOI: https://doi.org/10.1124/mol.105.015073

  15. Min, Kyung Hoon

    1. Involvement of IL-10 in Peroxisome Proliferator-Activated Receptor γ-Mediated Anti-Inflammatory Response in Asthma
      So Ri Kim, Kyung Sun Lee, Hee Sun Park, Seoung Ju Park, Kyung Hoon Min, Sun Mi Jin and Yong Chul Lee
      Molecular Pharmacology December 2005, 68 (6) 1568-1575; DOI: https://doi.org/10.1124/mol.105.017160

  16. Mohamedali, Khalid A.

    1. Vascular Targeting of Ocular Neovascularization with a Vascular Endothelial Growth Factor121/Gelonin Chimeric Protein
      Hideo Akiyama, Khalid A. Mohamedali, Raquel Lima e Silva, Shu Kachi, JiKui Shen, Christina Hatara, Naoyasu Umeda, Sean F. Hackett, Sadia Aslam, Melissa Krause, Hong Lai, Michael G. Rosenblum and Peter A. Campochiaro
      Molecular Pharmacology December 2005, 68 (6) 1543-1550; DOI: https://doi.org/10.1124/mol.105.015628

  17. Mohr, Klaus

    1. Atypical Muscarinic Allosteric Modulation: Cooperativity between Modulators and Their Atypical Binding Topology in Muscarinic M2 and M2/M5 Chimeric Receptors
      Christian Tränkle, Andreas Dittmann, Uwe Schulz, Oliver Weyand, Stefan Buller, Kirstin Jöhren, Eberhard Heller, Nigel J. M. Birdsall, Ulrike Holzgrabe, John Ellis, Hans Dieter Höltje and Klaus Mohr
      Molecular Pharmacology December 2005, 68 (6) 1597-1610; DOI: https://doi.org/10.1124/mol.105.017707

  18. Moreau, Emmanuel

    1. N-Substituted 4-Aminobenzamides (Procainamide Analogs): An Assessment of Multiple Cellular Effects Concerning Ion Trapping
      Guillaume Morissette, Emmanuel Moreau, René C.-Gaudreault and François Marceau
      Molecular Pharmacology December 2005, 68 (6) 1576-1589; DOI: https://doi.org/10.1124/mol.105.016527

  19. Morissette, Guillaume

    1. N-Substituted 4-Aminobenzamides (Procainamide Analogs): An Assessment of Multiple Cellular Effects Concerning Ion Trapping
      Guillaume Morissette, Emmanuel Moreau, René C.-Gaudreault and François Marceau
      Molecular Pharmacology December 2005, 68 (6) 1576-1589; DOI: https://doi.org/10.1124/mol.105.016527

  20. Mouri, Akihiro

    1. Long-Lasting Impairment of Associative Learning Is Correlated with a Dysfunction of N-Methyl-d-aspartate-Extracellular Signaling-Regulated Kinase Signaling in Mice after Withdrawal from Repeated Administration of Phencyclidine
      Takeshi Enomoto, Yukihiro Noda, Akihiro Mouri, Eun-Joo Shin, Dayong Wang, Rina Murai, Kazuo Hotta, Hiroshi Furukawa, Atsumi Nitta, Hyoung-Chun Kim and Toshitaka Nabeshima
      Molecular Pharmacology December 2005, 68 (6) 1765-1774; DOI: https://doi.org/10.1124/mol.105.011304

  21. Mulet, José

    1. Mutations of a Conserved Lysine Residue in the N-Terminal Domain of α7 Nicotinic Receptors Affect Gating and Binding of Nicotinic Agonists
      Manuel Criado, José Mulet, José A. Bernal, Susana Gerber, Salvador Sala and Francisco Sala
      Molecular Pharmacology December 2005, 68 (6) 1669-1677; DOI: https://doi.org/10.1124/mol.105.015446

  22. Murai, Rina

    1. Long-Lasting Impairment of Associative Learning Is Correlated with a Dysfunction of N-Methyl-d-aspartate-Extracellular Signaling-Regulated Kinase Signaling in Mice after Withdrawal from Repeated Administration of Phencyclidine
      Takeshi Enomoto, Yukihiro Noda, Akihiro Mouri, Eun-Joo Shin, Dayong Wang, Rina Murai, Kazuo Hotta, Hiroshi Furukawa, Atsumi Nitta, Hyoung-Chun Kim and Toshitaka Nabeshima
      Molecular Pharmacology December 2005, 68 (6) 1765-1774; DOI: https://doi.org/10.1124/mol.105.011304

N

  1. Nabeshima, Toshitaka

    1. Long-Lasting Impairment of Associative Learning Is Correlated with a Dysfunction of N-Methyl-d-aspartate-Extracellular Signaling-Regulated Kinase Signaling in Mice after Withdrawal from Repeated Administration of Phencyclidine
      Takeshi Enomoto, Yukihiro Noda, Akihiro Mouri, Eun-Joo Shin, Dayong Wang, Rina Murai, Kazuo Hotta, Hiroshi Furukawa, Atsumi Nitta, Hyoung-Chun Kim and Toshitaka Nabeshima
      Molecular Pharmacology December 2005, 68 (6) 1765-1774; DOI: https://doi.org/10.1124/mol.105.011304

  2. Nguyen, Theresa

    1. Redox Regulation of Cdc25B by Cell-Active Quinolinediones
      Marni Brisson, Theresa Nguyen, Peter Wipf, Beomjun Joo, Billy W. Day, John S. Skoko, Emanuel M. Schreiber, Caleb Foster, Pallavi Bansal and John S. Lazo
      Molecular Pharmacology December 2005, 68 (6) 1810-1820; DOI: https://doi.org/10.1124/mol.105.016360

  3. Nieddu, Erika

    1. Antihypertensive 1,4-Dihydropyridines as Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator Channel Gating Defect Caused by Cystic Fibrosis Mutations
      Nicoletta Pedemonte, Tullia Diena, Emanuela Caci, Erika Nieddu, Mauro Mazzei, Roberto Ravazzolo, Olga Zegarra-Moran and Luis J. V. Galietta
      Molecular Pharmacology December 2005, 68 (6) 1736-1746; DOI: https://doi.org/10.1124/mol.105.015149

  4. Nitiss, John L.

    1. Activation of the Unfolded Protein Response Is Necessary and Sufficient for Reducing Topoisomerase IIα Protein Levels and Decreasing Sensitivity to Topoisomerase-Targeted Drugs
      Miranda D. Gray, Melissa Mann, John L. Nitiss and Linda M. Hendershot
      Molecular Pharmacology December 2005, 68 (6) 1699-1707; DOI: https://doi.org/10.1124/mol.105.014753

  5. Nitta, Atsumi

    1. Long-Lasting Impairment of Associative Learning Is Correlated with a Dysfunction of N-Methyl-d-aspartate-Extracellular Signaling-Regulated Kinase Signaling in Mice after Withdrawal from Repeated Administration of Phencyclidine
      Takeshi Enomoto, Yukihiro Noda, Akihiro Mouri, Eun-Joo Shin, Dayong Wang, Rina Murai, Kazuo Hotta, Hiroshi Furukawa, Atsumi Nitta, Hyoung-Chun Kim and Toshitaka Nabeshima
      Molecular Pharmacology December 2005, 68 (6) 1765-1774; DOI: https://doi.org/10.1124/mol.105.011304

  6. Noda, Yukihiro

    1. Long-Lasting Impairment of Associative Learning Is Correlated with a Dysfunction of N-Methyl-d-aspartate-Extracellular Signaling-Regulated Kinase Signaling in Mice after Withdrawal from Repeated Administration of Phencyclidine
      Takeshi Enomoto, Yukihiro Noda, Akihiro Mouri, Eun-Joo Shin, Dayong Wang, Rina Murai, Kazuo Hotta, Hiroshi Furukawa, Atsumi Nitta, Hyoung-Chun Kim and Toshitaka Nabeshima
      Molecular Pharmacology December 2005, 68 (6) 1765-1774; DOI: https://doi.org/10.1124/mol.105.011304

  7. Nong, Yi

    1. A Close Structural Analog of 2-Methyl-6-(phenylethynyl)-pyridine Acts as a Neutral Allosteric Site Ligand on Metabotropic Glutamate Receptor Subtype 5 and Blocks the Effects of Multiple Allosteric Modulators
      Alice L. Rodriguez, Yi Nong, Nishant K. Sekaran, David Alagille, Gilles D. Tamagnan and P. Jeffrey Conn
      Molecular Pharmacology December 2005, 68 (6) 1793-1802; DOI: https://doi.org/10.1124/mol.105.016139

  8. Norman, Mark H.

    1. Proton Activation Does Not Alter Antagonist Interaction with the Capsaicin-Binding Pocket of TRPV1
      Narender R. Gavva, Rami Tamir, Lana Klionsky, Mark H. Norman, Jean-Claude Louis, Kenneth D. Wild and James J. S. Treanor
      Molecular Pharmacology December 2005, 68 (6) 1524-1533; DOI: https://doi.org/10.1124/mol.105.015727

O

  1. Oliva, Amelia

    1. A Novel Group of Genes Regulates Susceptibility to Antineoplastic Drugs in Highly Tumorigenic Breast Cancer Cells
      Julia C. Mallory, Gerard Crudden, Amelia Oliva, Christopher Saunders, Arnold Stromberg and Rolf J. Craven
      Molecular Pharmacology December 2005, 68 (6) 1747-1756; DOI: https://doi.org/10.1124/mol.105.016519

P

  1. Papineni, Sabitha

    1. 1,1-Bis(3′-indolyl)-1-(p-substitutedphenyl)methanes Are Peroxisome Proliferator-Activated Receptor γ Agonists but Decrease HCT-116 Colon Cancer Cell Survival through Receptor-Independent Activation of Early Growth Response-1 and Nonsteroidal Anti-Inflammatory Drug-Activated Gene-1
      Sudhakar Chintharlapalli, Sabitha Papineni, Seung Joon Baek, Shengxi Liu and Stephen Safe
      Molecular Pharmacology December 2005, 68 (6) 1782-1792; DOI: https://doi.org/10.1124/mol.105.017046

  2. Papke, Roger L.

    1. An α7 Nicotinic Acetylcholine Receptor Gain-of-Function Mutant That Retains Pharmacological Fidelity
      Andon N. Placzek, Francesca Grassi, Edwin M Meyer and Roger L. Papke
      Molecular Pharmacology December 2005, 68 (6) 1863-1876; DOI: https://doi.org/10.1124/mol.105.016402

  3. Park, Hee Sun

    1. Involvement of IL-10 in Peroxisome Proliferator-Activated Receptor γ-Mediated Anti-Inflammatory Response in Asthma
      So Ri Kim, Kyung Sun Lee, Hee Sun Park, Seoung Ju Park, Kyung Hoon Min, Sun Mi Jin and Yong Chul Lee
      Molecular Pharmacology December 2005, 68 (6) 1568-1575; DOI: https://doi.org/10.1124/mol.105.017160

  4. Park, Hyunsung

    1. Inhibition of the Catalytic Activity of Hypoxia-Inducible Factor-1α-Prolyl-Hydroxylase 2 by a MYND-Type Zinc Finger
      Kyung-Ok Choi, Taekyong Lee, Naery Lee, Ji-Hyun Kim, Eun Gyeong Yang, Jung Min Yoon, Jin Hwan Kim, Tae Gyu Lee and Hyunsung Park
      Molecular Pharmacology December 2005, 68 (6) 1803-1809; DOI: https://doi.org/10.1124/mol.105.015271

  5. Park, Seoung Ju

    1. Involvement of IL-10 in Peroxisome Proliferator-Activated Receptor γ-Mediated Anti-Inflammatory Response in Asthma
      So Ri Kim, Kyung Sun Lee, Hee Sun Park, Seoung Ju Park, Kyung Hoon Min, Sun Mi Jin and Yong Chul Lee
      Molecular Pharmacology December 2005, 68 (6) 1568-1575; DOI: https://doi.org/10.1124/mol.105.017160

  6. Pedemonte, Nicoletta

    1. Antihypertensive 1,4-Dihydropyridines as Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator Channel Gating Defect Caused by Cystic Fibrosis Mutations
      Nicoletta Pedemonte, Tullia Diena, Emanuela Caci, Erika Nieddu, Mauro Mazzei, Roberto Ravazzolo, Olga Zegarra-Moran and Luis J. V. Galietta
      Molecular Pharmacology December 2005, 68 (6) 1736-1746; DOI: https://doi.org/10.1124/mol.105.015149

  7. Picone, Robert P.

    1. (-)-7′-Isothiocyanato-11-hydroxy-1′,1′-dimethylheptylhexahydrocannabinol (AM841), a High-Affinity Electrophilic Ligand, Interacts Covalently with a Cysteine in Helix Six and Activates the CB1 Cannabinoid Receptor
      Robert P. Picone, Atmaram D. Khanolkar, Wei Xu, Lionel A. Ayotte, Ganesh A. Thakur, Dow P. Hurst, Mary E. Abood, Patricia H. Reggio, Donna J. Fournier and Alexandros Makriyannis
      Molecular Pharmacology December 2005, 68 (6) 1623-1635; DOI: https://doi.org/10.1124/mol.105.014407

  8. Placzek, Andon N.

    1. An α7 Nicotinic Acetylcholine Receptor Gain-of-Function Mutant That Retains Pharmacological Fidelity
      Andon N. Placzek, Francesca Grassi, Edwin M Meyer and Roger L. Papke
      Molecular Pharmacology December 2005, 68 (6) 1863-1876; DOI: https://doi.org/10.1124/mol.105.016402

R

  1. Ravazzolo, Roberto

    1. Antihypertensive 1,4-Dihydropyridines as Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator Channel Gating Defect Caused by Cystic Fibrosis Mutations
      Nicoletta Pedemonte, Tullia Diena, Emanuela Caci, Erika Nieddu, Mauro Mazzei, Roberto Ravazzolo, Olga Zegarra-Moran and Luis J. V. Galietta
      Molecular Pharmacology December 2005, 68 (6) 1736-1746; DOI: https://doi.org/10.1124/mol.105.015149

  2. Rebmann, Annegret

    1. Characterization of the First Potent and Selective PDE9 Inhibitor Using a cGMP Reporter Cell Line
      Frank Wunder, Adrian Tersteegen, Annegret Rebmann, Christina Erb, Thomas Fahrig and Martin Hendrix
      Molecular Pharmacology December 2005, 68 (6) 1775-1781; DOI: https://doi.org/10.1124/mol.105.017608

  3. Reggio, Patricia H.

    1. (-)-7′-Isothiocyanato-11-hydroxy-1′,1′-dimethylheptylhexahydrocannabinol (AM841), a High-Affinity Electrophilic Ligand, Interacts Covalently with a Cysteine in Helix Six and Activates the CB1 Cannabinoid Receptor
      Robert P. Picone, Atmaram D. Khanolkar, Wei Xu, Lionel A. Ayotte, Ganesh A. Thakur, Dow P. Hurst, Mary E. Abood, Patricia H. Reggio, Donna J. Fournier and Alexandros Makriyannis
      Molecular Pharmacology December 2005, 68 (6) 1623-1635; DOI: https://doi.org/10.1124/mol.105.014407

  4. Rocha, Walter

    1. Opposite Effects of Histone Deacetylase Inhibitors on Glucocorticoid and Estrogen Signaling in Human Endometrial Ishikawa Cells
      Walter Rocha, Rocio Sanchez, Julie Deschênes, Anick Auger, Elise Hébert, John H. White and Sylvie Mader
      Molecular Pharmacology December 2005, 68 (6) 1852-1862; DOI: https://doi.org/10.1124/mol.105.014514

  5. Rodriguez, Alice L.

    1. A Close Structural Analog of 2-Methyl-6-(phenylethynyl)-pyridine Acts as a Neutral Allosteric Site Ligand on Metabotropic Glutamate Receptor Subtype 5 and Blocks the Effects of Multiple Allosteric Modulators
      Alice L. Rodriguez, Yi Nong, Nishant K. Sekaran, David Alagille, Gilles D. Tamagnan and P. Jeffrey Conn
      Molecular Pharmacology December 2005, 68 (6) 1793-1802; DOI: https://doi.org/10.1124/mol.105.016139

  6. Rosenblum, Michael G.

    1. Vascular Targeting of Ocular Neovascularization with a Vascular Endothelial Growth Factor121/Gelonin Chimeric Protein
      Hideo Akiyama, Khalid A. Mohamedali, Raquel Lima e Silva, Shu Kachi, JiKui Shen, Christina Hatara, Naoyasu Umeda, Sean F. Hackett, Sadia Aslam, Melissa Krause, Hong Lai, Michael G. Rosenblum and Peter A. Campochiaro
      Molecular Pharmacology December 2005, 68 (6) 1543-1550; DOI: https://doi.org/10.1124/mol.105.015628

S

  1. Safe, Stephen

    1. 1,1-Bis(3′-indolyl)-1-(p-substitutedphenyl)methanes Are Peroxisome Proliferator-Activated Receptor γ Agonists but Decrease HCT-116 Colon Cancer Cell Survival through Receptor-Independent Activation of Early Growth Response-1 and Nonsteroidal Anti-Inflammatory Drug-Activated Gene-1
      Sudhakar Chintharlapalli, Sabitha Papineni, Seung Joon Baek, Shengxi Liu and Stephen Safe
      Molecular Pharmacology December 2005, 68 (6) 1782-1792; DOI: https://doi.org/10.1124/mol.105.017046

  2. Sala, Francisco

    1. Mutations of a Conserved Lysine Residue in the N-Terminal Domain of α7 Nicotinic Receptors Affect Gating and Binding of Nicotinic Agonists
      Manuel Criado, José Mulet, José A. Bernal, Susana Gerber, Salvador Sala and Francisco Sala
      Molecular Pharmacology December 2005, 68 (6) 1669-1677; DOI: https://doi.org/10.1124/mol.105.015446

  3. Sala, Salvador

    1. Mutations of a Conserved Lysine Residue in the N-Terminal Domain of α7 Nicotinic Receptors Affect Gating and Binding of Nicotinic Agonists
      Manuel Criado, José Mulet, José A. Bernal, Susana Gerber, Salvador Sala and Francisco Sala
      Molecular Pharmacology December 2005, 68 (6) 1669-1677; DOI: https://doi.org/10.1124/mol.105.015446

  4. Sanchez, Rocio

    1. Opposite Effects of Histone Deacetylase Inhibitors on Glucocorticoid and Estrogen Signaling in Human Endometrial Ishikawa Cells
      Walter Rocha, Rocio Sanchez, Julie Deschênes, Anick Auger, Elise Hébert, John H. White and Sylvie Mader
      Molecular Pharmacology December 2005, 68 (6) 1852-1862; DOI: https://doi.org/10.1124/mol.105.014514

  5. Sanders, Matthew

    1. Induction of δ Opioid Receptor Function by Up-Regulation of Membrane Receptors in Mouse Primary Afferent Neurons
      Wendy Walwyn, Nigel T. Maidment, Matthew Sanders, Christopher J. Evans, Brigitte L. Kieffer and Tim G. Hales
      Molecular Pharmacology December 2005, 68 (6) 1688-1698; DOI: https://doi.org/10.1124/mol.105.014829

  6. Sang, Hairong

    1. Stereospecific Induction of Nuclear Factor-κB Activation by Isochamaejasmin
      Qinghai Tian, Jing Li, Xin Xie, Meiling Sun, Hairong Sang, Caihong Zhou, Tianying An, Lihong Hu, Richard D. Ye and Ming-Wei Wang
      Molecular Pharmacology December 2005, 68 (6) 1534-1542; DOI: https://doi.org/10.1124/mol.105.014720

  7. Saunders, Christopher

    1. A Novel Group of Genes Regulates Susceptibility to Antineoplastic Drugs in Highly Tumorigenic Breast Cancer Cells
      Julia C. Mallory, Gerard Crudden, Amelia Oliva, Christopher Saunders, Arnold Stromberg and Rolf J. Craven
      Molecular Pharmacology December 2005, 68 (6) 1747-1756; DOI: https://doi.org/10.1124/mol.105.016519

  8. Schreiber, Emanuel M.

    1. Redox Regulation of Cdc25B by Cell-Active Quinolinediones
      Marni Brisson, Theresa Nguyen, Peter Wipf, Beomjun Joo, Billy W. Day, John S. Skoko, Emanuel M. Schreiber, Caleb Foster, Pallavi Bansal and John S. Lazo
      Molecular Pharmacology December 2005, 68 (6) 1810-1820; DOI: https://doi.org/10.1124/mol.105.016360

  9. Schulz, Uwe

    1. Atypical Muscarinic Allosteric Modulation: Cooperativity between Modulators and Their Atypical Binding Topology in Muscarinic M2 and M2/M5 Chimeric Receptors
      Christian Tränkle, Andreas Dittmann, Uwe Schulz, Oliver Weyand, Stefan Buller, Kirstin Jöhren, Eberhard Heller, Nigel J. M. Birdsall, Ulrike Holzgrabe, John Ellis, Hans Dieter Höltje and Klaus Mohr
      Molecular Pharmacology December 2005, 68 (6) 1597-1610; DOI: https://doi.org/10.1124/mol.105.017707

  10. Schwarz, Wolfgang

    1. Identification and Selective Inhibition of the Channel Mode of the Neuronal GABA Transporter 1
      Stephan Krause and Wolfgang Schwarz
      Molecular Pharmacology December 2005, 68 (6) 1728-1735; DOI: https://doi.org/10.1124/mol.105.013870

  11. Sekaran, Nishant K.

    1. A Close Structural Analog of 2-Methyl-6-(phenylethynyl)-pyridine Acts as a Neutral Allosteric Site Ligand on Metabotropic Glutamate Receptor Subtype 5 and Blocks the Effects of Multiple Allosteric Modulators
      Alice L. Rodriguez, Yi Nong, Nishant K. Sekaran, David Alagille, Gilles D. Tamagnan and P. Jeffrey Conn
      Molecular Pharmacology December 2005, 68 (6) 1793-1802; DOI: https://doi.org/10.1124/mol.105.016139

  12. Shen, JiKui

    1. Vascular Targeting of Ocular Neovascularization with a Vascular Endothelial Growth Factor121/Gelonin Chimeric Protein
      Hideo Akiyama, Khalid A. Mohamedali, Raquel Lima e Silva, Shu Kachi, JiKui Shen, Christina Hatara, Naoyasu Umeda, Sean F. Hackett, Sadia Aslam, Melissa Krause, Hong Lai, Michael G. Rosenblum and Peter A. Campochiaro
      Molecular Pharmacology December 2005, 68 (6) 1543-1550; DOI: https://doi.org/10.1124/mol.105.015628

  13. Shin, Eun-Joo

    1. Long-Lasting Impairment of Associative Learning Is Correlated with a Dysfunction of N-Methyl-d-aspartate-Extracellular Signaling-Regulated Kinase Signaling in Mice after Withdrawal from Repeated Administration of Phencyclidine
      Takeshi Enomoto, Yukihiro Noda, Akihiro Mouri, Eun-Joo Shin, Dayong Wang, Rina Murai, Kazuo Hotta, Hiroshi Furukawa, Atsumi Nitta, Hyoung-Chun Kim and Toshitaka Nabeshima
      Molecular Pharmacology December 2005, 68 (6) 1765-1774; DOI: https://doi.org/10.1124/mol.105.011304

  14. Siems, William F.

    1. Effects of Drugs with Muscle-Related Side Effects and Affinity for Calsequestrin on the Calcium Regulatory Function of Sarcoplasmic Reticulum Microsomes
      EunJung Kim, Maggie Tam, William F. Siems and ChulHee Kang
      Molecular Pharmacology December 2005, 68 (6) 1708-1715; DOI: https://doi.org/10.1124/mol.105.016253

  15. Skoko, John S.

    1. Redox Regulation of Cdc25B by Cell-Active Quinolinediones
      Marni Brisson, Theresa Nguyen, Peter Wipf, Beomjun Joo, Billy W. Day, John S. Skoko, Emanuel M. Schreiber, Caleb Foster, Pallavi Bansal and John S. Lazo
      Molecular Pharmacology December 2005, 68 (6) 1810-1820; DOI: https://doi.org/10.1124/mol.105.016360

  16. Slitt, Angela L.

    1. Retinoid X Receptor α Regulates the Expression of Glutathione S-transferase Genes and Modulates Acetaminophen-Glutathione Conjugation in Mouse Liver
      Guoli Dai, Nathan Chou, Lin He, Maxwell A. Gyamfi, Alphonse J. Mendy, Angela L. Slitt, Curtis D. Klaassen and Yu-Jui Y. Wan
      Molecular Pharmacology December 2005, 68 (6) 1590-1596; DOI: https://doi.org/10.1124/mol.105.013680

  17. Smith, Victoria

    1. Pharmacodynamics of the G-Quadruplex-Stabilizing Telomerase Inhibitor 3,11-Difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in Vitro: Activity in Human Tumor Cells Correlates with Telomere Length and Can Be Enhanced, or Antagonized, with Cytotoxic Agents
      Jennifer C. Cookson, Fangping Dai, Victoria Smith, Robert A. Heald, Charles A. Laughton, Malcolm F. G. Stevens and Angelika M. Burger
      Molecular Pharmacology December 2005, 68 (6) 1551-1558; DOI: https://doi.org/10.1124/mol.105.013300

  18. Stevens, Malcolm F. G.

    1. Pharmacodynamics of the G-Quadruplex-Stabilizing Telomerase Inhibitor 3,11-Difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in Vitro: Activity in Human Tumor Cells Correlates with Telomere Length and Can Be Enhanced, or Antagonized, with Cytotoxic Agents
      Jennifer C. Cookson, Fangping Dai, Victoria Smith, Robert A. Heald, Charles A. Laughton, Malcolm F. G. Stevens and Angelika M. Burger
      Molecular Pharmacology December 2005, 68 (6) 1551-1558; DOI: https://doi.org/10.1124/mol.105.013300

  19. Stromberg, Arnold

    1. A Novel Group of Genes Regulates Susceptibility to Antineoplastic Drugs in Highly Tumorigenic Breast Cancer Cells
      Julia C. Mallory, Gerard Crudden, Amelia Oliva, Christopher Saunders, Arnold Stromberg and Rolf J. Craven
      Molecular Pharmacology December 2005, 68 (6) 1747-1756; DOI: https://doi.org/10.1124/mol.105.016519

  20. Sun, Meiling

    1. Stereospecific Induction of Nuclear Factor-κB Activation by Isochamaejasmin
      Qinghai Tian, Jing Li, Xin Xie, Meiling Sun, Hairong Sang, Caihong Zhou, Tianying An, Lihong Hu, Richard D. Ye and Ming-Wei Wang
      Molecular Pharmacology December 2005, 68 (6) 1534-1542; DOI: https://doi.org/10.1124/mol.105.014720

T

  1. Tam, Maggie

    1. Effects of Drugs with Muscle-Related Side Effects and Affinity for Calsequestrin on the Calcium Regulatory Function of Sarcoplasmic Reticulum Microsomes
      EunJung Kim, Maggie Tam, William F. Siems and ChulHee Kang
      Molecular Pharmacology December 2005, 68 (6) 1708-1715; DOI: https://doi.org/10.1124/mol.105.016253

  2. Tamagnan, Gilles D.

    1. A Close Structural Analog of 2-Methyl-6-(phenylethynyl)-pyridine Acts as a Neutral Allosteric Site Ligand on Metabotropic Glutamate Receptor Subtype 5 and Blocks the Effects of Multiple Allosteric Modulators
      Alice L. Rodriguez, Yi Nong, Nishant K. Sekaran, David Alagille, Gilles D. Tamagnan and P. Jeffrey Conn
      Molecular Pharmacology December 2005, 68 (6) 1793-1802; DOI: https://doi.org/10.1124/mol.105.016139

  3. Tamir, Rami

    1. Proton Activation Does Not Alter Antagonist Interaction with the Capsaicin-Binding Pocket of TRPV1
      Narender R. Gavva, Rami Tamir, Lana Klionsky, Mark H. Norman, Jean-Claude Louis, Kenneth D. Wild and James J. S. Treanor
      Molecular Pharmacology December 2005, 68 (6) 1524-1533; DOI: https://doi.org/10.1124/mol.105.015727

  4. Tang, Guanghua

    1. Direct Stimulation of KATP Channels by Exogenous and Endogenous Hydrogen Sulfide in Vascular Smooth Muscle Cells
      Guanghua Tang, Lingyun Wu, Wenbin Liang and Rui Wang
      Molecular Pharmacology December 2005, 68 (6) 1757-1764; DOI: https://doi.org/10.1124/mol.105.017467

  5. Tersteegen, Adrian

    1. Characterization of the First Potent and Selective PDE9 Inhibitor Using a cGMP Reporter Cell Line
      Frank Wunder, Adrian Tersteegen, Annegret Rebmann, Christina Erb, Thomas Fahrig and Martin Hendrix
      Molecular Pharmacology December 2005, 68 (6) 1775-1781; DOI: https://doi.org/10.1124/mol.105.017608

  6. Thakur, Ganesh A.

    1. (-)-7′-Isothiocyanato-11-hydroxy-1′,1′-dimethylheptylhexahydrocannabinol (AM841), a High-Affinity Electrophilic Ligand, Interacts Covalently with a Cysteine in Helix Six and Activates the CB1 Cannabinoid Receptor
      Robert P. Picone, Atmaram D. Khanolkar, Wei Xu, Lionel A. Ayotte, Ganesh A. Thakur, Dow P. Hurst, Mary E. Abood, Patricia H. Reggio, Donna J. Fournier and Alexandros Makriyannis
      Molecular Pharmacology December 2005, 68 (6) 1623-1635; DOI: https://doi.org/10.1124/mol.105.014407

  7. Thomas, M. Bijoy

    1. Gemcitabine-Induced Activation of Checkpoint Signaling Pathways That Affect Tumor Cell Survival
      Larry M. Karnitz, Karen S. Flatten, Jill M. Wagner, David Loegering, Jennifer S. Hackbarth, Sonnet J. H. Arlander, Benjamin T. Vroman, M. Bijoy Thomas, Yong-Un Baek, Kevin M. Hopkins, Howard B. Lieberman, Junjie Chen, William A. Cliby and Scott H. Kaufmann
      Molecular Pharmacology December 2005, 68 (6) 1636-1644; DOI: https://doi.org/10.1124/mol.105.012716

  8. Tian, Qinghai

    1. Stereospecific Induction of Nuclear Factor-κB Activation by Isochamaejasmin
      Qinghai Tian, Jing Li, Xin Xie, Meiling Sun, Hairong Sang, Caihong Zhou, Tianying An, Lihong Hu, Richard D. Ye and Ming-Wei Wang
      Molecular Pharmacology December 2005, 68 (6) 1534-1542; DOI: https://doi.org/10.1124/mol.105.014720

  9. Tränkle, Christian

    1. Atypical Muscarinic Allosteric Modulation: Cooperativity between Modulators and Their Atypical Binding Topology in Muscarinic M2 and M2/M5 Chimeric Receptors
      Christian Tränkle, Andreas Dittmann, Uwe Schulz, Oliver Weyand, Stefan Buller, Kirstin Jöhren, Eberhard Heller, Nigel J. M. Birdsall, Ulrike Holzgrabe, John Ellis, Hans Dieter Höltje and Klaus Mohr
      Molecular Pharmacology December 2005, 68 (6) 1597-1610; DOI: https://doi.org/10.1124/mol.105.017707

  10. Treanor, James J. S.

    1. Proton Activation Does Not Alter Antagonist Interaction with the Capsaicin-Binding Pocket of TRPV1
      Narender R. Gavva, Rami Tamir, Lana Klionsky, Mark H. Norman, Jean-Claude Louis, Kenneth D. Wild and James J. S. Treanor
      Molecular Pharmacology December 2005, 68 (6) 1524-1533; DOI: https://doi.org/10.1124/mol.105.015727

U

  1. Umeda, Naoyasu

    1. Vascular Targeting of Ocular Neovascularization with a Vascular Endothelial Growth Factor121/Gelonin Chimeric Protein
      Hideo Akiyama, Khalid A. Mohamedali, Raquel Lima e Silva, Shu Kachi, JiKui Shen, Christina Hatara, Naoyasu Umeda, Sean F. Hackett, Sadia Aslam, Melissa Krause, Hong Lai, Michael G. Rosenblum and Peter A. Campochiaro
      Molecular Pharmacology December 2005, 68 (6) 1543-1550; DOI: https://doi.org/10.1124/mol.105.015628

V

  1. Vroman, Benjamin T.

    1. Gemcitabine-Induced Activation of Checkpoint Signaling Pathways That Affect Tumor Cell Survival
      Larry M. Karnitz, Karen S. Flatten, Jill M. Wagner, David Loegering, Jennifer S. Hackbarth, Sonnet J. H. Arlander, Benjamin T. Vroman, M. Bijoy Thomas, Yong-Un Baek, Kevin M. Hopkins, Howard B. Lieberman, Junjie Chen, William A. Cliby and Scott H. Kaufmann
      Molecular Pharmacology December 2005, 68 (6) 1636-1644; DOI: https://doi.org/10.1124/mol.105.012716

W

  1. Wagner, Jill M.

    1. Gemcitabine-Induced Activation of Checkpoint Signaling Pathways That Affect Tumor Cell Survival
      Larry M. Karnitz, Karen S. Flatten, Jill M. Wagner, David Loegering, Jennifer S. Hackbarth, Sonnet J. H. Arlander, Benjamin T. Vroman, M. Bijoy Thomas, Yong-Un Baek, Kevin M. Hopkins, Howard B. Lieberman, Junjie Chen, William A. Cliby and Scott H. Kaufmann
      Molecular Pharmacology December 2005, 68 (6) 1636-1644; DOI: https://doi.org/10.1124/mol.105.012716

  2. Walwyn, Wendy

    1. Induction of δ Opioid Receptor Function by Up-Regulation of Membrane Receptors in Mouse Primary Afferent Neurons
      Wendy Walwyn, Nigel T. Maidment, Matthew Sanders, Christopher J. Evans, Brigitte L. Kieffer and Tim G. Hales
      Molecular Pharmacology December 2005, 68 (6) 1688-1698; DOI: https://doi.org/10.1124/mol.105.014829

  3. Wan, Yu-Jui Y.

    1. Retinoid X Receptor α Regulates the Expression of Glutathione S-transferase Genes and Modulates Acetaminophen-Glutathione Conjugation in Mouse Liver
      Guoli Dai, Nathan Chou, Lin He, Maxwell A. Gyamfi, Alphonse J. Mendy, Angela L. Slitt, Curtis D. Klaassen and Yu-Jui Y. Wan
      Molecular Pharmacology December 2005, 68 (6) 1590-1596; DOI: https://doi.org/10.1124/mol.105.013680

  4. Wang, Dayong

    1. Long-Lasting Impairment of Associative Learning Is Correlated with a Dysfunction of N-Methyl-d-aspartate-Extracellular Signaling-Regulated Kinase Signaling in Mice after Withdrawal from Repeated Administration of Phencyclidine
      Takeshi Enomoto, Yukihiro Noda, Akihiro Mouri, Eun-Joo Shin, Dayong Wang, Rina Murai, Kazuo Hotta, Hiroshi Furukawa, Atsumi Nitta, Hyoung-Chun Kim and Toshitaka Nabeshima
      Molecular Pharmacology December 2005, 68 (6) 1765-1774; DOI: https://doi.org/10.1124/mol.105.011304

  5. Wang, Ming-Wei

    1. Stereospecific Induction of Nuclear Factor-κB Activation by Isochamaejasmin
      Qinghai Tian, Jing Li, Xin Xie, Meiling Sun, Hairong Sang, Caihong Zhou, Tianying An, Lihong Hu, Richard D. Ye and Ming-Wei Wang
      Molecular Pharmacology December 2005, 68 (6) 1534-1542; DOI: https://doi.org/10.1124/mol.105.014720

  6. Wang, Rui

    1. Direct Stimulation of KATP Channels by Exogenous and Endogenous Hydrogen Sulfide in Vascular Smooth Muscle Cells
      Guanghua Tang, Lingyun Wu, Wenbin Liang and Rui Wang
      Molecular Pharmacology December 2005, 68 (6) 1757-1764; DOI: https://doi.org/10.1124/mol.105.017467

  7. Ward, Richard J.

    1. A Key Serine for the GTPase-Activating Protein Function of Regulator of G Protein Signaling Proteins Is Not a General Target for 14-3-3 Interactions
      Richard J. Ward and Graeme Milligan
      Molecular Pharmacology December 2005, 68 (6) 1821-1830; DOI: https://doi.org/10.1124/mol.105.015073

  8. Wess, Jürgen

    1. Allosteric Binding Sites on Muscarinic Acetylcholine Receptors
      Jürgen Wess
      Molecular Pharmacology December 2005, 68 (6) 1506-1509; DOI: https://doi.org/10.1124/mol.105.019141

  9. Weyand, Oliver

    1. Atypical Muscarinic Allosteric Modulation: Cooperativity between Modulators and Their Atypical Binding Topology in Muscarinic M2 and M2/M5 Chimeric Receptors
      Christian Tränkle, Andreas Dittmann, Uwe Schulz, Oliver Weyand, Stefan Buller, Kirstin Jöhren, Eberhard Heller, Nigel J. M. Birdsall, Ulrike Holzgrabe, John Ellis, Hans Dieter Höltje and Klaus Mohr
      Molecular Pharmacology December 2005, 68 (6) 1597-1610; DOI: https://doi.org/10.1124/mol.105.017707

  10. White, John H.

    1. Opposite Effects of Histone Deacetylase Inhibitors on Glucocorticoid and Estrogen Signaling in Human Endometrial Ishikawa Cells
      Walter Rocha, Rocio Sanchez, Julie Deschênes, Anick Auger, Elise Hébert, John H. White and Sylvie Mader
      Molecular Pharmacology December 2005, 68 (6) 1852-1862; DOI: https://doi.org/10.1124/mol.105.014514

  11. Wild, Kenneth D.

    1. Proton Activation Does Not Alter Antagonist Interaction with the Capsaicin-Binding Pocket of TRPV1
      Narender R. Gavva, Rami Tamir, Lana Klionsky, Mark H. Norman, Jean-Claude Louis, Kenneth D. Wild and James J. S. Treanor
      Molecular Pharmacology December 2005, 68 (6) 1524-1533; DOI: https://doi.org/10.1124/mol.105.015727

  12. Wipf, Peter

    1. Redox Regulation of Cdc25B by Cell-Active Quinolinediones
      Marni Brisson, Theresa Nguyen, Peter Wipf, Beomjun Joo, Billy W. Day, John S. Skoko, Emanuel M. Schreiber, Caleb Foster, Pallavi Bansal and John S. Lazo
      Molecular Pharmacology December 2005, 68 (6) 1810-1820; DOI: https://doi.org/10.1124/mol.105.016360

  13. Wolfe, Barry B.

    1. Nicotinic Cholinergic Receptors in the Rat Retina: Simple and Mixed Heteromeric Subtypes
      Andrea M. Marritt, Brandon C. Cox, Robert P. Yasuda, J. Michael McIntosh, Yingxian Xiao, Barry B. Wolfe and Kenneth J. Kellar
      Molecular Pharmacology December 2005, 68 (6) 1656-1668; DOI: https://doi.org/10.1124/mol.105.012369

  14. Wu, Jiarui

    1. Apoptosis Induced by a New Member of Saponin Family Is Mediated through Caspase-8-Dependent Cleavage of Bcl-2
      Jianbei Zhu, Lei Xiong, Biao Yu and Jiarui Wu
      Molecular Pharmacology December 2005, 68 (6) 1831-1838; DOI: https://doi.org/10.1124/mol.105.015826

  15. Wu, Lingyun

    1. Direct Stimulation of KATP Channels by Exogenous and Endogenous Hydrogen Sulfide in Vascular Smooth Muscle Cells
      Guanghua Tang, Lingyun Wu, Wenbin Liang and Rui Wang
      Molecular Pharmacology December 2005, 68 (6) 1757-1764; DOI: https://doi.org/10.1124/mol.105.017467

  16. Wunder, Frank

    1. Characterization of the First Potent and Selective PDE9 Inhibitor Using a cGMP Reporter Cell Line
      Frank Wunder, Adrian Tersteegen, Annegret Rebmann, Christina Erb, Thomas Fahrig and Martin Hendrix
      Molecular Pharmacology December 2005, 68 (6) 1775-1781; DOI: https://doi.org/10.1124/mol.105.017608

X

  1. Xiao, Yingxian

    1. Nicotinic Cholinergic Receptors in the Rat Retina: Simple and Mixed Heteromeric Subtypes
      Andrea M. Marritt, Brandon C. Cox, Robert P. Yasuda, J. Michael McIntosh, Yingxian Xiao, Barry B. Wolfe and Kenneth J. Kellar
      Molecular Pharmacology December 2005, 68 (6) 1656-1668; DOI: https://doi.org/10.1124/mol.105.012369

  2. Xie, Xin

    1. Stereospecific Induction of Nuclear Factor-κB Activation by Isochamaejasmin
      Qinghai Tian, Jing Li, Xin Xie, Meiling Sun, Hairong Sang, Caihong Zhou, Tianying An, Lihong Hu, Richard D. Ye and Ming-Wei Wang
      Molecular Pharmacology December 2005, 68 (6) 1534-1542; DOI: https://doi.org/10.1124/mol.105.014720

  3. Xin, Xianliang

    1. Sulfated Polymannuroguluronate, a Novel Anti-AIDS Drug Candidate, Inhibits T Cell Apoptosis by Combating Oxidative Damage of Mitochondria
      Benchun Miao, Jing Li, Xueyan Fu, Li Gan, Xianliang Xin and Meiyu Geng
      Molecular Pharmacology December 2005, 68 (6) 1716-1727; DOI: https://doi.org/10.1124/mol.105.015412

  4. Xiong, Lei

    1. Apoptosis Induced by a New Member of Saponin Family Is Mediated through Caspase-8-Dependent Cleavage of Bcl-2
      Jianbei Zhu, Lei Xiong, Biao Yu and Jiarui Wu
      Molecular Pharmacology December 2005, 68 (6) 1831-1838; DOI: https://doi.org/10.1124/mol.105.015826

  5. Xu, Wei

    1. (-)-7′-Isothiocyanato-11-hydroxy-1′,1′-dimethylheptylhexahydrocannabinol (AM841), a High-Affinity Electrophilic Ligand, Interacts Covalently with a Cysteine in Helix Six and Activates the CB1 Cannabinoid Receptor
      Robert P. Picone, Atmaram D. Khanolkar, Wei Xu, Lionel A. Ayotte, Ganesh A. Thakur, Dow P. Hurst, Mary E. Abood, Patricia H. Reggio, Donna J. Fournier and Alexandros Makriyannis
      Molecular Pharmacology December 2005, 68 (6) 1623-1635; DOI: https://doi.org/10.1124/mol.105.014407

Y

  1. Yang, Eun Gyeong

    1. Inhibition of the Catalytic Activity of Hypoxia-Inducible Factor-1α-Prolyl-Hydroxylase 2 by a MYND-Type Zinc Finger
      Kyung-Ok Choi, Taekyong Lee, Naery Lee, Ji-Hyun Kim, Eun Gyeong Yang, Jung Min Yoon, Jin Hwan Kim, Tae Gyu Lee and Hyunsung Park
      Molecular Pharmacology December 2005, 68 (6) 1803-1809; DOI: https://doi.org/10.1124/mol.105.015271

  2. Yasuda, Robert P.

    1. Nicotinic Cholinergic Receptors in the Rat Retina: Simple and Mixed Heteromeric Subtypes
      Andrea M. Marritt, Brandon C. Cox, Robert P. Yasuda, J. Michael McIntosh, Yingxian Xiao, Barry B. Wolfe and Kenneth J. Kellar
      Molecular Pharmacology December 2005, 68 (6) 1656-1668; DOI: https://doi.org/10.1124/mol.105.012369

  3. Ye, Richard D.

    1. Stereospecific Induction of Nuclear Factor-κB Activation by Isochamaejasmin
      Qinghai Tian, Jing Li, Xin Xie, Meiling Sun, Hairong Sang, Caihong Zhou, Tianying An, Lihong Hu, Richard D. Ye and Ming-Wei Wang
      Molecular Pharmacology December 2005, 68 (6) 1534-1542; DOI: https://doi.org/10.1124/mol.105.014720

  4. Yoon, Jung Min

    1. Inhibition of the Catalytic Activity of Hypoxia-Inducible Factor-1α-Prolyl-Hydroxylase 2 by a MYND-Type Zinc Finger
      Kyung-Ok Choi, Taekyong Lee, Naery Lee, Ji-Hyun Kim, Eun Gyeong Yang, Jung Min Yoon, Jin Hwan Kim, Tae Gyu Lee and Hyunsung Park
      Molecular Pharmacology December 2005, 68 (6) 1803-1809; DOI: https://doi.org/10.1124/mol.105.015271

  5. Yu, Biao

    1. Apoptosis Induced by a New Member of Saponin Family Is Mediated through Caspase-8-Dependent Cleavage of Bcl-2
      Jianbei Zhu, Lei Xiong, Biao Yu and Jiarui Wu
      Molecular Pharmacology December 2005, 68 (6) 1831-1838; DOI: https://doi.org/10.1124/mol.105.015826

Z

  1. Zegarra-Moran, Olga

    1. Antihypertensive 1,4-Dihydropyridines as Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator Channel Gating Defect Caused by Cystic Fibrosis Mutations
      Nicoletta Pedemonte, Tullia Diena, Emanuela Caci, Erika Nieddu, Mauro Mazzei, Roberto Ravazzolo, Olga Zegarra-Moran and Luis J. V. Galietta
      Molecular Pharmacology December 2005, 68 (6) 1736-1746; DOI: https://doi.org/10.1124/mol.105.015149

  2. Zhou, Caihong

    1. Stereospecific Induction of Nuclear Factor-κB Activation by Isochamaejasmin
      Qinghai Tian, Jing Li, Xin Xie, Meiling Sun, Hairong Sang, Caihong Zhou, Tianying An, Lihong Hu, Richard D. Ye and Ming-Wei Wang
      Molecular Pharmacology December 2005, 68 (6) 1534-1542; DOI: https://doi.org/10.1124/mol.105.014720

  3. Zhu, Jianbei

    1. Apoptosis Induced by a New Member of Saponin Family Is Mediated through Caspase-8-Dependent Cleavage of Bcl-2
      Jianbei Zhu, Lei Xiong, Biao Yu and Jiarui Wu
      Molecular Pharmacology December 2005, 68 (6) 1831-1838; DOI: https://doi.org/10.1124/mol.105.015826
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