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Research ArticleArticle

A Glutathione S-Transferase π-Activated Prodrug Causes Kinase Activation Concurrent with S-Glutathionylation of Proteins

Danyelle M. Townsend, Victoria J. Findlay, Farit Fazilev, Molly Ogle, Jacob Fraser, Joseph E. Saavedra, Xinhua Ji, Larry K. Keefer and Kenneth D. Tew
Molecular Pharmacology February 2006, 69 (2) 501-508; DOI: https://doi.org/10.1124/mol.105.018523

Article Information

vol. 69 no. 2 501-508
DOI 
https://doi.org/10.1124/mol.105.018523
PubMed 
16288082
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received August 31, 2005
  • Accepted November 8, 2005
  • Published online January 17, 2006.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Danyelle M. Townsend,
  2. Victoria J. Findlay,
  3. Farit Fazilev,
  4. Molly Ogle,
  5. Jacob Fraser,
  6. Joseph E. Saavedra,
  7. Xinhua Ji,
  8. Larry K. Keefer and
  9. Kenneth D. Tew
  1. Deptartments of Pharmaceutical Science (D.M.T.) and Cell and Molecular Pharmacology (V.J.F., M.O., J.F., K.D.T.), Medical University of South Carolina, Charleston, South Carolina; Fox Chase Cancer Center, Philadelphia, Pennsylvania (F.F.); Basic Research Program, SAIC-Frederick, Inc., Frederick, Maryland (J.E.S.); and Macromolecular Crystallography Laboratory (X.J.) and Laboratory of Comparative Carcinogenesis (L.K.K.), National Cancer Institute, Frederick, Maryland
  1. Address correspondence to:
    Kenneth D. Tew, Medical University of South Carolina, 173 Ashley Ave., PO Box 250505, Charleston, SC 29425. E-mail: tewk{at}musc.edu
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Research ArticleArticle

A Glutathione S-Transferase π-Activated Prodrug Causes Kinase Activation Concurrent with S-Glutathionylation of Proteins

Danyelle M. Townsend, Victoria J. Findlay, Farit Fazilev, Molly Ogle, Jacob Fraser, Joseph E. Saavedra, Xinhua Ji, Larry K. Keefer and Kenneth D. Tew
Molecular Pharmacology February 1, 2006, 69 (2) 501-508; DOI: https://doi.org/10.1124/mol.105.018523
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