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Research ArticleArticle

On the Mechanism of Interaction of Potent Surmountable and Insurmountable Antagonists with the Prostaglandin D2 Receptor CRTH2

Jesper Mosolff Mathiesen, Arthur Christopoulos, Trond Ulven, Julia F. Royer, Mercedes Campillo, Akos Heinemann, Leonardo Pardo and Evi Kostenis
Molecular Pharmacology April 2006, 69 (4) 1441-1453; DOI: https://doi.org/10.1124/mol.105.017681

Article Information

vol. 69 no. 4 1441-1453
DOI 
https://doi.org/10.1124/mol.105.017681
PubMed 
16418339
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received August 8, 2005
  • Accepted January 17, 2006
  • Published online March 21, 2006.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Jesper Mosolff Mathiesen,
  2. Arthur Christopoulos,
  3. Trond Ulven,
  4. Julia F. Royer,
  5. Mercedes Campillo,
  6. Akos Heinemann,
  7. Leonardo Pardo and
  8. Evi Kostenis
  1. 7TM Pharma A/S, Hørsholm, Denmark (J.M.M., E.K., T.U.); Department of Pharmacology, Monash University, Victoria, Australia (A.C.); Department of Experimental and Clinical Pharmacology, Medical University Graz, Graz, Austria (J.F.R., A.H.); Laboratorio de Medicina Computacional, Unidad de Bioestadistica, Facultad de Medicina, Universidad Autonoma de Barcelona, Barcelona, Spain (M.C., L.P.); and Department of Chemistry, University of Southern Denmark, Odense, Denmark (T.U.)
  1. Address correspondence to:
    Dr. Evi Kostenis, 7TM Pharma A/S, Fremtidsvej 3, 2970 Hørsholm, Denmark. E-mail: ek{at}7tm.com
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Research ArticleArticle

On the Mechanism of Interaction of Potent Surmountable and Insurmountable Antagonists with the Prostaglandin D2 Receptor CRTH2

Jesper Mosolff Mathiesen, Arthur Christopoulos, Trond Ulven, Julia F. Royer, Mercedes Campillo, Akos Heinemann, Leonardo Pardo and Evi Kostenis
Molecular Pharmacology April 1, 2006, 69 (4) 1441-1453; DOI: https://doi.org/10.1124/mol.105.017681
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