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Molecular Pharmacology

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Table of Contents

May 01, 2006; Volume 69,Issue 5

Perspectives

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    No Nitric Oxide for HO-1 from Sodium Nitroprusside
    Henning Schröder
    Molecular Pharmacology May 2006, 69 (5) 1507-1509; DOI: https://doi.org/10.1124/mol.106.023416
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    New Assignments for Multitasking Signal Transduction Inhibitors
    Zhihong Zhang and Kathryn E. Meier
    Molecular Pharmacology May 2006, 69 (5) 1510-1512; DOI: https://doi.org/10.1124/mol.106.023721

Accelerated Communication

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    Structural Model Reveals Key Interactions in the Assembly of the Pregnane X Receptor/Corepressor Complex
    Ching Y. Wang, Chia W. Li, J. Don Chen and William J. Welsh
    Molecular Pharmacology May 2006, 69 (5) 1513-1517; DOI: https://doi.org/10.1124/mol.106.022368

Articles

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    Molecular Determinants in the Second Intracellular Loop of the 5-Hydroxytryptamine-1A Receptor for G-Protein Coupling
    Neena Kushwaha, Shannon C. Harwood, Ariel M. Wilson, Miles Berger, Laurence H. Tecott, Bryan L. Roth and Paul R. Albert
    Molecular Pharmacology May 2006, 69 (5) 1518-1526; DOI: https://doi.org/10.1124/mol.105.019844
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    Potent Inhibition of Platelet-Derived Growth Factor-Induced Responses in Vascular Smooth Muscle Cells by BMS-354825 (Dasatinib)
    Zhengming Chen, Francis Y. Lee, Kapil N. Bhalla and Jie Wu
    Molecular Pharmacology May 2006, 69 (5) 1527-1533; DOI: https://doi.org/10.1124/mol.105.020172
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    Liver Deformation in Ahr-Null Mice: Evidence for Aberrant Hepatic Perfusion In Early Development
    Eric B. Harstad, Christopher A. Guite, Tami L. Thomae and Christopher A. Bradfield
    Molecular Pharmacology May 2006, 69 (5) 1534-1541; DOI: https://doi.org/10.1124/mol.105.020107
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    Electrophysiological Characterization and Modeling of the Structure Activity Relationship of the Human Concentrative Nucleoside Transporter 3 (hCNT3)
    Huankai Hu, Christopher J. Endres, Cheng Chang, Nagavedi S. Umapathy, Eun-Woo Lee, You-Jun Fei, Shirou Itagaki, Peter W. Swaan, Vadivel Ganapathy and Jashvant D. Unadkat
    Molecular Pharmacology May 2006, 69 (5) 1542-1553; DOI: https://doi.org/10.1124/mol.105.018945
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    trans-Stilbene Oxide Induces Expression of Genes Involved in Metabolism and Transport in Mouse Liver via CAR and Nrf2 Transcription Factors
    A. L. Slitt, N. J. Cherrington, M. Z. Dieter, L. M. Aleksunes, G. L. Scheffer, W. Huang, D. D. Moore and C. D. Klaassen
    Molecular Pharmacology May 2006, 69 (5) 1554-1563; DOI: https://doi.org/10.1124/mol.105.014571
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    Peroxisome Proliferator-Activated Receptor γ-Independent Repression of Prostate-Specific Antigen Expression by Thiazolidinediones in Prostate Cancer Cells
    Chih-Cheng Yang, Chia-Yu Ku, Shuo Wei, Chung-Wai Shiau, Chang-Shi Chen, Joseph J. Pinzone, Mathew D. Ringel and Ching-Shih Chen
    Molecular Pharmacology May 2006, 69 (5) 1564-1570; DOI: https://doi.org/10.1124/mol.105.018333
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    Differential Regulation of the Cell-Surface Targeting and Function of β- and α1-Adrenergic Receptors by Rab1 GTPase in Cardiac Myocytes
    Catalin M. Filipeanu, Fuguo Zhou, Erin K. Fugetta and Guangyu Wu
    Molecular Pharmacology May 2006, 69 (5) 1571-1578; DOI: https://doi.org/10.1124/mol.105.019984
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    Celecoxib Inhibits Interleukin-12 αβ and β2 Folding and Secretion by a Novel COX2-Independent Mechanism Involving Chaperones of the Endoplasmic Reticulum
    Iraide Alloza, Andy Baxter, Qian Chen, Rune Matthiesen and Koen Vandenbroeck
    Molecular Pharmacology May 2006, 69 (5) 1579-1587; DOI: https://doi.org/10.1124/mol.105.020669
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    Carboxyl-Terminal Splicing Enhances Physical Interactions between the Cytoplasmic Tails of Purinergic P2X Receptors
    Taka-aki Koshimizu, Karla Kretschmannova, Mu-Lan He, Susumu Ueno, Akito Tanoue, Nobuyuki Yanagihara, Stanko S. Stojilkovic and Gozoh Tsujimoto
    Molecular Pharmacology May 2006, 69 (5) 1588-1598; DOI: https://doi.org/10.1124/mol.105.019802
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    Dioxin Induces an Estrogen-Like, Estrogen Receptor-Dependent Gene Expression Response in the Murine Uterus
    Darrell R. Boverhof, Joshua C. Kwekel, Daryl G. Humes, Lyle D. Burgoon and Timothy R. Zacharewski
    Molecular Pharmacology May 2006, 69 (5) 1599-1606; DOI: https://doi.org/10.1124/mol.105.019638
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    Apurinic/Apyrimidinic Endonuclease-1 Protein Level Is Associated with the Cytotoxicity of l-Configuration Deoxycytidine Analogs (Troxacitabine and β-l-2′,3′-Dideoxy-2′,3′-didehydro-5-fluorocytidine) but Not d-Configuration Deoxycytidine Analogs (Gemcitabine and β-d-Arabinofuranosylcytosine)
    Wing Lam, Shin-Young Park, Chung-Hang Leung and Yung-Chi Cheng
    Molecular Pharmacology May 2006, 69 (5) 1607-1614; DOI: https://doi.org/10.1124/mol.105.021527
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    Raloxifene-Induced Myeloma Cell Apoptosis: A Study of Nuclear Factor-κB Inhibition and Gene Expression Signature
    Sabine Olivier, Pierre Close, Emilie Castermans, Laurence de Leval, Sebastien Tabruyn, Alain Chariot, Michel Malaise, Marie-Paule Merville, Vincent Bours and Nathalie Franchimont
    Molecular Pharmacology May 2006, 69 (5) 1615-1623; DOI: https://doi.org/10.1124/mol.105.020479
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    Cytosolic Entry of Bisphosphonate Drugs Requires Acidification of Vesicles after Fluid-Phase Endocytosis
    Keith Thompson, Michael J. Rogers, Fraser P. Coxon and Julie C. Crockett
    Molecular Pharmacology May 2006, 69 (5) 1624-1632; DOI: https://doi.org/10.1124/mol.105.020776
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    Iron Released by Sodium Nitroprusside Contributes to Heme Oxygenase-1 Induction via the cAMP-Protein Kinase A-Mitogen-Activated Protein Kinase Pathway in RAW 264.7 Cells
    Hye Jung Kim, Irina Tsoy, Min Kyu Park, Young Soo Lee, Jae Heun Lee, Han Geuk Seo and Ki Churl Chang
    Molecular Pharmacology May 2006, 69 (5) 1633-1640; DOI: https://doi.org/10.1124/mol.105.020487
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    Identification of Various Allosteric Interaction Sites on M1 Muscarinic Receptor Using 125I-Met35-Oxidized Muscarinic Toxin 7
    Carole Fruchart-Gaillard, Gilles Mourier, Catherine Marquer, André Ménez and Denis Servent
    Molecular Pharmacology May 2006, 69 (5) 1641-1651; DOI: https://doi.org/10.1124/mol.105.020883
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    Allosteric Modulation of Binding Properties between Units of Chemokine Receptor Homo- and Hetero-Oligomers
    Jean-Yves Springael, Phu Nguyen Le Minh, Eneko Urizar, Sabine Costagliola, Gilbert Vassart and Marc Parmentier
    Molecular Pharmacology May 2006, 69 (5) 1652-1661; DOI: https://doi.org/10.1124/mol.105.019414
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    Induction of AKR1C2 by Phase II Inducers: Identification of a Distal Consensus Antioxidant Response Element Regulated by NRF2
    Huan Lou, Shouying Du, Qing Ji and Andrew Stolz
    Molecular Pharmacology May 2006, 69 (5) 1662-1672; DOI: https://doi.org/10.1124/mol.105.019794
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    Species Diversity and Peptide Toxins Blocking Selectivity of Ether-à-go-go-Related Gene Subfamily K+ Channels in the Central Nervous System
    Rita Restano-Cassulini, Yuliya V. Korolkova, Sylvie Diochot, Georgina Gurrola, Leonardo Guasti, Lourival D. Possani, Michel Lazdunski, Eugene V. Grishin, Annarosa Arcangeli and Enzo Wanke
    Molecular Pharmacology May 2006, 69 (5) 1673-1683; DOI: https://doi.org/10.1124/mol.105.019729
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    Short- and Long-Term Amiodarone Treatments Regulate Cav3.2 Low-Voltage-Activated T-type Ca2+ Channel through Distinct Mechanisms
    Noboru Yamashita, Toshihiko Kaku, Tomoko Uchino, Shojiro Isomoto, Hironobu Yoshimatsu and Katsushige Ono
    Molecular Pharmacology May 2006, 69 (5) 1684-1691; DOI: https://doi.org/10.1124/mol.105.021253
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    An Uncharged Region within the N Terminus of the P2X6 Receptor Inhibits Its Assembly and Exit from the Endoplasmic Reticulum
    Susan J. Ormond, Nelson P. Barrera, Omar S. Qureshi, Robert M. Henderson, J. Michael Edwardson and Ruth D. Murrell-Lagnado
    Molecular Pharmacology May 2006, 69 (5) 1692-1700; DOI: https://doi.org/10.1124/mol.105.020404
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    Mechanisms Underlying Lipopolysaccharide-Induced Kinin B1 Receptor Up-Regulation in the Pig Iris Sphincter in Vitro
    Mariem El Sayah, Rodrigo Medeiros, Elizabeth S. Fernandes, Maria M. Campos and João B. Calixto
    Molecular Pharmacology May 2006, 69 (5) 1701-1708; DOI: https://doi.org/10.1124/mol.105.021097
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    Molecular Determinants of hERG Channel Block
    Kaichiro Kamiya, Ryoko Niwa, John S. Mitcheson and Michael C. Sanguinetti
    Molecular Pharmacology May 2006, 69 (5) 1709-1716; DOI: https://doi.org/10.1124/mol.105.020990
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    Opposite Effects of Wortmannin and 2-(4-Morpholinyl)-8-phenyl-1(4H)-benzopyran-4-one Hydrochloride on Toll-Like Receptor-Mediated Nitric Oxide Production: Negative Regulation of Nuclear Factor-κB by Phosphoinositide 3-Kinase
    Kaoru Hazeki, Sachiko Kinoshita, Takayo Matsumura, Kiyomi Nigorikawa, Hiroshi Kubo and Osamu Hazeki
    Molecular Pharmacology May 2006, 69 (5) 1717-1724; DOI: https://doi.org/10.1124/mol.105.021162
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    Angiotensin-Converting Enzyme (ACE) Dimerization Is the Initial Step in the ACE Inhibitor-Induced ACE Signaling Cascade in Endothelial Cells
    Karin Kohlstedt, Cynthia Gershome, Matthias Friedrich, Werner Muller-Esterl, François Alhenc-Gelas, Rudi Busse and Ingrid Fleming
    Molecular Pharmacology May 2006, 69 (5) 1725-1732; DOI: https://doi.org/10.1124/mol.105.020636
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    Flubendiamide, a Novel Ca2+ Channel Modulator, Reveals Evidence for Functional Cooperation between Ca2+ Pumps and Ca2+ Release
    Takao Masaki, Noriaki Yasokawa, Masanori Tohnishi, Tetsuyoshi Nishimatsu, Kenji Tsubata, Kazuyoshi Inoue, Kazuhiko Motoba and Takashi Hirooka
    Molecular Pharmacology May 2006, 69 (5) 1733-1739; DOI: https://doi.org/10.1124/mol.105.020339
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    19nor-1,25-Dihydroxyvitamin D2 Specifically Induces CYP3A9 in Rat Intestine More Strongly than 1,25-Dihydroxyvitamin D3 in Vivo and in Vitro
    Claudia Zierold, Jamie A. Mings and Hector F. Deluca
    Molecular Pharmacology May 2006, 69 (5) 1740-1747; DOI: https://doi.org/10.1124/mol.105.019851
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    Human REV1 Modulates the Cytotoxicity and Mutagenicity of Cisplatin in Human Ovarian Carcinoma Cells
    Xinjian Lin, Tsuyoshi Okuda, Julie Trang and Stephen B. Howell
    Molecular Pharmacology May 2006, 69 (5) 1748-1754; DOI: https://doi.org/10.1124/mol.105.020446
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    Halothane Directly Modifies Na+ and K+ Channel Activities in Cultured Human Alveolar Epithelial Cells
    Antoine Roch, Vadim Shlyonsky, Arnaud Goolaerts, Frédérique Mies and Sarah Sariban-Sohraby
    Molecular Pharmacology May 2006, 69 (5) 1755-1762; DOI: https://doi.org/10.1124/mol.105.021485
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    Dexamethasone-Induced Ras Protein 1 Negatively Regulates Protein Kinase C δ: Implications for Adenylyl Cyclase 2 Signaling
    Chau H. Nguyen and Val J. Watts
    Molecular Pharmacology May 2006, 69 (5) 1763-1771; DOI: https://doi.org/10.1124/mol.105.019133
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Molecular Pharmacology: 69 (5)
Molecular Pharmacology
Vol. 69, Issue 5
1 May 2006
  • Table of Contents
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  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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