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Molecular Pharmacology

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Table of Contents

June 01, 2006; Volume 69,Issue 6

Perspective

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    Potential Therapeutic Gene for the Treatment of Ischemic Disease: Ad2/Hypoxia-Inducible Factor-1α (HIF-1)/VP16 Enhances B-Type Natriuretic Peptide Gene Expression via a HIF-1-Responsive Element
    Michael E. Wilhide and W. Keith Jones
    Molecular Pharmacology June 2006, 69 (6) 1773-1778; DOI: https://doi.org/10.1124/mol.106.024968

Accelerated Communication

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    Enantiomers of Neuroactive Steroids Support a Specific Interaction with the GABA-C Receptor as the Mechanism of Steroid Action
    Wenjun Li, Douglas F. Covey, Juha-Matti Alakoskela, Paavo K. J. Kinnunen and Joe Henry Steinbach
    Molecular Pharmacology June 2006, 69 (6) 1779-1782; DOI: https://doi.org/10.1124/mol.106.022863

Articles

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    Decursin Inhibits Induction of Inflammatory Mediators by Blocking Nuclear Factor-κB Activation in Macrophages
    Jung-Hee Kim, Ji-Hye Jeong, Sung-Tak Jeon, Ho Kim, Jiyeon Ock, Kyoungho Suk, Sang-In Kim, Kyung-Sik Song and Won-ha Lee
    Molecular Pharmacology June 2006, 69 (6) 1783-1790; DOI: https://doi.org/10.1124/mol.105.021048
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    IκB Kinase-2-Independent and -Dependent Inflammation in Airway Disease Models: Relevance of IKK-2 Inhibition to the Clinic
    Mark A. Birrell, Sissie Wong, Elizabeth L. Hardaker, Matthew C. Catley, Kerryn McCluskie, Michael Collins, Saleem Haj-Yahia and Maria G. Belvisi
    Molecular Pharmacology June 2006, 69 (6) 1791-1800; DOI: https://doi.org/10.1124/mol.105.019521
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    Development of a Novel Nitro-Derivative of Noscapine for the Potential Treatment of Drug-Resistant Ovarian Cancer and T-Cell Lymphoma
    Ritu Aneja, Surya N. Vangapandu, Manu Lopus, Ramesh Chandra, Dulal Panda and Harish C. Joshi
    Molecular Pharmacology June 2006, 69 (6) 1801-1809; DOI: https://doi.org/10.1124/mol.105.021899
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    Short- and Long-Term Regulation of Adenylyl Cyclase Activity by δ-Opioid Receptor Are Mediated by Gαi2 in Neuroblastoma N2A Cells
    Lei Zhang, Joan Tetrault, Wei Wang, Horace H. Loh and Ping-Yee Law
    Molecular Pharmacology June 2006, 69 (6) 1810-1819; DOI: https://doi.org/10.1124/mol.105.021352
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    Suppression and Regression of Choroidal Neovascularization by Systemic Administration of an α5β1 Integrin Antagonist
    Naoyasu Umeda, Shu Kachi, Hideo Akiyama, Grit Zahn, Doerte Vossmeyer, Roland Stragies and Peter A. Campochiaro
    Molecular Pharmacology June 2006, 69 (6) 1820-1828; DOI: https://doi.org/10.1124/mol.105.020941
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    Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN) Reduces Vascular Endothelial Growth Factor Expression in Allergen-Induced Airway Inflammation
    Kyung Sun Lee, So Ri Kim, Seoung Ju Park, Ho Kyung Lee, Hee Sun Park, Kyung Hoon Min, Sun Mi Jin and Yong Chul Lee
    Molecular Pharmacology June 2006, 69 (6) 1829-1839; DOI: https://doi.org/10.1124/mol.106.022228
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    A Novel Vitamin D Derivative Activates Bone Morphogenetic Protein Signaling in MCF10 Breast Epithelial Cells
    Hong Jin Lee, Andrew Wislocki, Catherine Goodman, Yan Ji, Rongrong Ge, Hubert Maehr, Milan Uskokovic, Michael Reiss and Nanjoo Suh
    Molecular Pharmacology June 2006, 69 (6) 1840-1848; DOI: https://doi.org/10.1124/mol.105.022079
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    Determination of Binding Site Residues Responsible for the Subunit Selectivity of Novel Marine-Derived Compounds on Kainate Receptors
    James M. Sanders, Olli T. Pentikäinen, Luca Settimo, Ulla Pentikäinen, Muneo Shoji, Makoto Sasaki, Ryuichi Sakai, Mark S. Johnson and Geoffrey T. Swanson
    Molecular Pharmacology June 2006, 69 (6) 1849-1860; DOI: https://doi.org/10.1124/mol.106.022772
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    Antieosinophilic Activity of Orazipone
    Hannu Kankaanranta, Pinja Ilmarinen, Xianzhi Zhang, Erkki Nissinen and Eeva Moilanen
    Molecular Pharmacology June 2006, 69 (6) 1861-1870; DOI: https://doi.org/10.1124/mol.105.021170
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    Novel Compound 2-Methyl-2H-pyrazole-3-carboxylic Acid (2-methyl-4-o-tolylazo-phenyl)-amide (CH-223191) Prevents 2,3,7,8-TCDD-Induced Toxicity by Antagonizing the Aryl Hydrocarbon Receptor
    Sun-Hee Kim, Ellen C. Henry, Dong-Kyu Kim, Yun-Hee Kim, Kum Joo Shin, Myoung Sook Han, Taehoon G. Lee, Jong-Ku Kang, Thomas A. Gasiewicz, Sung Ho Ryu and Pann-Ghill Suh
    Molecular Pharmacology June 2006, 69 (6) 1871-1878; DOI: https://doi.org/10.1124/mol.105.021832
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    Induction of Apoptosis in Renal Cell Carcinoma by Reactive Oxygen Species: Involvement of Extracellular Signal-Regulated Kinase 1/2, p38δ/γ, Cyclooxygenase-2 Down-Regulation, and Translocation of Apoptosis-Inducing Factor
    Monica Ambrose, Aideen Ryan, Gerald C. O'Sullivan, Colum Dunne and Orla P. Barry
    Molecular Pharmacology June 2006, 69 (6) 1879-1890; DOI: https://doi.org/10.1124/mol.105.020875
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    Mutations Distal to the Substrate Site Can Affect Varicella Zoster Virus Thymidine Kinase Activity: Implications for Drug Design
    Kamel El Omari, Sandra Liekens, Louise E. Bird, Jan Balzarini and David K. Stammers
    Molecular Pharmacology June 2006, 69 (6) 1891-1896; DOI: https://doi.org/10.1124/mol.106.023002
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    Endoplasmic Reticulum-Associated Degradation of Cytochrome P450 CYP3A4 in Saccharomyces cerevisiae: Further Characterization of Cellular Participants and Structural Determinants
    Mingxiang Liao, Saadia Faouzi, Andrey Karyakin and Maria Almira Correia
    Molecular Pharmacology June 2006, 69 (6) 1897-1904; DOI: https://doi.org/10.1124/mol.105.021816
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    The Two-State Dimer Receptor Model: A General Model for Receptor Dimers
    Rafael Franco, Vicent Casadó, Josefa Mallol, Carla Ferrada, Sergi Ferré, Kjell Fuxe, Antoni Cortés, Francisco Ciruela, Carmen Lluis and Enric I. Canela
    Molecular Pharmacology June 2006, 69 (6) 1905-1912; DOI: https://doi.org/10.1124/mol.105.020685
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    Transactivation of Rat Apical Sodium-Dependent Bile Acid Transporter and Increased Bile Acid Transport by 1α,25-Dihydroxyvitamin D3 via the Vitamin D Receptor
    Xianghai Chen, Frank Chen, Shanjun Liu, Hartmut Glaeser, Paul A. Dawson, Alan F. Hofmann, Richard B. Kim, Benjamin L. Shneider and K. Sandy Pang
    Molecular Pharmacology June 2006, 69 (6) 1913-1923; DOI: https://doi.org/10.1124/mol.105.020792
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    A Common Regulatory Region Functions Bidirectionally in Transcriptional Activation of the Human CYP1A1 and CYP1A2 Genes
    Rika Ueda, Hiromi Iketaki, Kiyoshi Nagata, Shioko Kimura, Frank J. Gonzalez, Kazutomi Kusano, Tsutomu Yoshimura and Yasushi Yamazoe
    Molecular Pharmacology June 2006, 69 (6) 1924-1930; DOI: https://doi.org/10.1124/mol.105.021220
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    Phoneutria nigriventer Toxin 1: A Novel, State-Dependent Inhibitor of Neuronal Sodium Channels That Interacts with μ Conotoxin Binding Sites
    Nicole Martin-Moutot, Pascal Mansuelle, Gisèle Alcaraz, Raquel Gouvêa Dos Santos, Marta N. Cordeiro, Maria Elena De Lima, Michael Seagar and Catherine Van Renterghem
    Molecular Pharmacology June 2006, 69 (6) 1931-1937; DOI: https://doi.org/10.1124/mol.105.021147
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    Suppression of the Phosphorylation of Receptor Tyrosine Phosphatase-α on the Src-Independent Site Tyrosine 789 by Reactive Oxygen Species
    Qin Hao, Stacey A. Rutherford, Brad Low and Hua Tang
    Molecular Pharmacology June 2006, 69 (6) 1938-1944; DOI: https://doi.org/10.1124/mol.105.020115
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    2-Fluoro-3-(4-nitro-phenyl)deschloroepibatidine Is a Novel Potent Competitive Antagonist of Human Neuronal α4β2 nAChRs
    Galya R. Abdrakhmanova, M. Imad Damaj, F. Ivy Carroll and Billy R. Martin
    Molecular Pharmacology June 2006, 69 (6) 1945-1952; DOI: https://doi.org/10.1124/mol.105.021782
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    A Constitutively Active Hypoxia-Inducible Factor-1α/VP16 Hybrid Factor Activates Expression of the Human B-Type Natriuretic Peptide Gene
    Yuxia Luo, Canwen Jiang, Adam J. Belanger, Geoffrey Y. Akita, Samuel C. Wadsworth, Richard J. Gregory and Karen A. Vincent
    Molecular Pharmacology June 2006, 69 (6) 1953-1962; DOI: https://doi.org/10.1124/mol.105.017905
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    T-Type Calcium Channels Are Inhibited by Fluoxetine and Its Metabolite Norfluoxetine
    Achraf Traboulsie, Jean Chemin, Elodie Kupfer, Joël Nargeot and Philippe Lory
    Molecular Pharmacology June 2006, 69 (6) 1963-1968; DOI: https://doi.org/10.1124/mol.105.020842
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    Desensitization of NO/cGMP Signaling in Smooth Muscle: Blood Vessels Versus Airways
    Florian Mullershausen, Alexander Lange, Evanthia Mergia, Andreas Friebe and Doris Koesling
    Molecular Pharmacology June 2006, 69 (6) 1969-1974; DOI: https://doi.org/10.1124/mol.105.020909
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    Potentiation of Native and Recombinant P2X7-Mediated Calcium Signaling by Arachidonic Acid in Cultured Cortical Astrocytes and Human Embryonic Kidney 293 Cells
    Susanna Alloisio, Rita Aiello, Stefano Ferroni and Mario Nobile
    Molecular Pharmacology June 2006, 69 (6) 1975-1983; DOI: https://doi.org/10.1124/mol.105.020164
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    Distinct Receptor Activity-Modifying Protein Domains Differentially Modulate Interaction with Calcitonin Receptors
    Madhara Udawela, George Christopoulos, Nanda Tilakaratne, Arthur Christopoulos, Anthony Albiston and Patrick M. Sexton
    Molecular Pharmacology June 2006, 69 (6) 1984-1989; DOI: https://doi.org/10.1124/mol.105.021915
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    The Interaction of an Impermeant Cation with the Sheep Cardiac RyR Channel Alters Ryanoid Association
    Bhavna Tanna, William Welch, Luc Ruest, John L. Sutko and Alan J. Williams
    Molecular Pharmacology June 2006, 69 (6) 1990-1997; DOI: https://doi.org/10.1124/mol.105.021659
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    Neurochemical Characterization of a Neuroprotective Compound from Parawixia bistriata Spider Venom That Inhibits Synaptosomal Uptake of GABA and Glycine
    Renê Oliveira Beleboni, Renato Guizzo, Andréia Cristina Karklin Fontana, Andrea Baldocchi Pizzo, Ruither Oliveira Gomes Carolino, Leonardo Gobbo-Neto, Norberto Peporine Lopes, Joaquim Coutinho-Netto and Wagner Ferreira dos Santos
    Molecular Pharmacology June 2006, 69 (6) 1998-2006; DOI: https://doi.org/10.1124/mol.105.017319
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    Recombinant Enzymes Overexpressed in Bacteria Show Broad Catalytic Specificity of Human Cytochrome P450 2W1 and Limited Activity of Human Cytochrome P450 2S1
    Zhong-Liu Wu, Christal D. Sohl, Tsutomu Shimada and F. Peter Guengerich
    Molecular Pharmacology June 2006, 69 (6) 2007-2014; DOI: https://doi.org/10.1124/mol.106.023648
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    Dual Potentiating and Inhibitory Actions of a Benz[e]indene Neurosteroid Analog on Recombinant α1β2γ2 GABAA Receptors
    Ping Li, Douglas F. Covey, Joe Henry Steinbach and Gustav Akk
    Molecular Pharmacology June 2006, 69 (6) 2015-2026; DOI: https://doi.org/10.1124/mol.106.022590
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    In Vitro and in Vivo Nuclear Factor-κB Inhibitory Effects of the Cell-Penetrating Penetratin Peptide
    Tamás Letoha, Erzsébet Kusz, Gábor Pápai, Annamária Szabolcs, József Kaszaki, Ilona Varga, Tamás Takács, Botond Penke and Ernő Duda
    Molecular Pharmacology June 2006, 69 (6) 2027-2036; DOI: https://doi.org/10.1124/mol.105.019653
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    Modulation by LL-37 of the Responses of Salivary Glands to Purinergic Agonists
    Stéphanie Pochet, Séverine Tandel, Stéphanie Querriére, Marie Tre-Hardy, Mikel Garcia-Marcos, Manuela De Lorenzi, Michel Vandenbranden, Aida Marino, Michel Devleeschouwer and Jean-Paul Dehaye
    Molecular Pharmacology June 2006, 69 (6) 2037-2046; DOI: https://doi.org/10.1124/mol.105.021444
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    Ultrasound Stimulates Cyclooxygenase-2 Expression and Increases Bone Formation through Integrin, Focal Adhesion Kinase, Phosphatidylinositol 3-Kinase, and Akt Pathway in Osteoblasts
    Chih-Hsin Tang, Rong-Sen Yang, Tsang-Hai Huang, Dah-Yuu Lu, Woei-Jer Chuang, Tur-Fu Huang and Wen-Mei Fu
    Molecular Pharmacology June 2006, 69 (6) 2047-2057; DOI: https://doi.org/10.1124/mol.105.022160
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    The Suramin Analog 4,4′,4″,4″′-(Carbonylbis(imino-5,1,3-benzenetriylbis (carbonylimino)))tetra-kis-benzenesulfonic Acid (NF110) Potently Blocks P2X3 Receptors: Subtype Selectivity Is Determined by Location of Sulfonic Acid Groups
    Ralf Hausmann, Jürgen Rettinger, Zoltan Gerevich, Sabine Meis, Matthias U. Kassack, Peter Illes, Günter Lambrecht and Günther Schmalzing
    Molecular Pharmacology June 2006, 69 (6) 2058-2067; DOI: https://doi.org/10.1124/mol.106.022665
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    Gα12/13- and Rho-Dependent Activation of Phospholipase C-ϵ by Lysophosphatidic Acid and Thrombin Receptors
    Melinda D. Hains, Michele R. Wing, Savitri Maddileti, David P. Siderovski and T. Kendall Harden
    Molecular Pharmacology June 2006, 69 (6) 2068-2075; DOI: https://doi.org/10.1124/mol.105.017921
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    The Aryl Hydrocarbon Receptor Agonist 2,3,7,8-Tetrachlorodibenzo-p-dioxin Alters the Circadian Rhythms, Quiescence, and Expression of Clock Genes in Murine Hematopoietic Stem and Progenitor Cells
    Russell W. Garrett and Thomas A. Gasiewicz
    Molecular Pharmacology June 2006, 69 (6) 2076-2083; DOI: https://doi.org/10.1124/mol.105.021006
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    Sulfotransferase (SULT) 1A1 Polymorphic Variants *1, *2, and *3 Are Associated with Altered Enzymatic Activity, Cellular Phenotype, and Protein Degradation
    Swati Nagar, Susan Walther and Rebecca L. Blanchard
    Molecular Pharmacology June 2006, 69 (6) 2084-2092; DOI: https://doi.org/10.1124/mol.105.019240
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Molecular Pharmacology: 69 (6)
Molecular Pharmacology
Vol. 69, Issue 6
1 Jun 2006
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