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Molecular Pharmacology

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Table of Contents

July 01, 2006; Volume 70,Issue 1

Perspectives

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    Class B GPCRs: A Hidden Agonist Within?
    Martin Beinborn
    Molecular Pharmacology July 2006, 70 (1) 1-4; DOI: https://doi.org/10.1124/mol.106.025932
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    Potentiation of Acetylcholine Receptors by Divalent Cations
    Jon Lindstrom
    Molecular Pharmacology July 2006, 70 (1) 5-7; DOI: https://doi.org/10.1124/mol.106.025767

Accelerated Communication

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    The Aryl Hydrocarbon Receptor Signaling Pathway Is Modified through Interactions with a Kelch Protein
    Elizabeth E. Dunham, Emily A. Stevens, Edward Glover and Christopher A. Bradfield
    Molecular Pharmacology July 2006, 70 (1) 8-15; DOI: https://doi.org/10.1124/mol.106.024380

Articles

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    Role of the Outer β-Sheet in Divalent Cation Modulation of α7 Nicotinic Receptors
    James T. McLaughlin, Jie Fu, Adrian D. Sproul and Robert L. Rosenberg
    Molecular Pharmacology July 2006, 70 (1) 16-22; DOI: https://doi.org/10.1124/mol.106.023259
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    High Accumulation of Platinum-DNA Adducts in Strial Marginal Cells of the Cochlea Is an Early Event in Cisplatin but Not Carboplatin Ototoxicity
    Jan Peter Thomas, Juergen Lautermann, Bernd Liedert, Frank Seiler and Juergen Thomale
    Molecular Pharmacology July 2006, 70 (1) 23-29; DOI: https://doi.org/10.1124/mol.106.022244
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    The Phenotypic Differentiation of Locus Ceruleus Noradrenergic Neurons Mediated by Brain-Derived Neurotrophic Factor Is Enhanced by Corticotropin Releasing Factor through the Activation of a cAMP-Dependent Signaling Pathway
    Sabine Traver, Marc Marien, Elodie Martin, Etienne C. Hirsch and Patrick P. Michel
    Molecular Pharmacology July 2006, 70 (1) 30-40; DOI: https://doi.org/10.1124/mol.106.022715
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    Sphingosine and Its Analog, the Immunosuppressant 2-Amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol, Interact with the CB1 Cannabinoid Receptor
    Steven W. Paugh, Michael P. Cassidy, Hengjun He, Sheldon Milstien, Laura J. Sim-Selley, Sarah Spiegel and Dana E. Selley
    Molecular Pharmacology July 2006, 70 (1) 41-50; DOI: https://doi.org/10.1124/mol.105.020552
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    A Cannabinoid Quinone Inhibits Angiogenesis by Targeting Vascular Endothelial Cells
    Natalya M. Kogan, Cristina Blázquez, Luis Álvarez, Ruth Gallily, Michael Schlesinger, Manuel Guzmán and Raphael Mechoulam
    Molecular Pharmacology July 2006, 70 (1) 51-59; DOI: https://doi.org/10.1124/mol.105.021089
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    Identification of Tubulin as the Molecular Target of Proapoptotic Pyrrolo-1,5-benzoxazepines
    Jude M. Mulligan, Lisa M. Greene, Suzanne Cloonan, Margaret M. Mc Gee, Valeria Onnis, Giuseppe Campiani, Caterina Fattorusso, Mark Lawler, D. Clive Williams and Daniela M. Zisterer
    Molecular Pharmacology July 2006, 70 (1) 60-70; DOI: https://doi.org/10.1124/mol.105.021204
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    Receptor Regulation of Gene Expression of Axon Guidance Molecules: Implications for Adaptation
    Amy K. Jassen, Hong Yang, Gregory M. Miller, Elizabeth Calder and Bertha K. Madras
    Molecular Pharmacology July 2006, 70 (1) 71-77; DOI: https://doi.org/10.1124/mol.105.021998
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    Agonist-Induced Cell Surface Trafficking of an Intracellularly Sequestered D1 Dopamine Receptor Homo-Oligomer
    Michael M. C. Kong, Theresa Fan, George Varghese, Brian F. O'Dowd and Susan R. George
    Molecular Pharmacology July 2006, 70 (1) 78-89; DOI: https://doi.org/10.1124/mol.105.021246
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    Phosducin and Phosducin-like Protein Attenuate G-Protein-Coupled Receptor-Mediated Inhibition of Voltage-Gated Calcium Channels in Rat Sympathetic Neurons
    John G. Partridge, Henry L. Puhl and Stephen R. Ikeda
    Molecular Pharmacology July 2006, 70 (1) 90-100; DOI: https://doi.org/10.1124/mol.105.021394
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    Interleukin-2 Suppression by 2-Arachidonyl Glycerol Is Mediated through Peroxisome Proliferator-Activated Receptor γ Independently of Cannabinoid Receptors 1 and 2
    Cheryl E. Rockwell, Natasha T. Snider, Jerry T. Thompson, John P. Vanden Heuvel and Norbert E. Kaminski
    Molecular Pharmacology July 2006, 70 (1) 101-111; DOI: https://doi.org/10.1124/mol.105.019117
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    Resveratrol Suppresses Tumor Necrosis Factor-α-Induced Fractalkine Expression in Endothelial Cells
    Sang-Ok Moon, Won Kim, Mi Jeong Sung, Sik Lee, Kyung Pyo Kang, Duk Hoon Kim, Sang Yong Lee, June-No So and Sung Kwang Park
    Molecular Pharmacology July 2006, 70 (1) 112-119; DOI: https://doi.org/10.1124/mol.106.022392
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    Structure-Function Analysis of Vitamin D 24-Hydroxylase (CYP24A1) by Site-Directed Mutagenesis: Amino Acid Residues Responsible for Species-Based Difference of CYP24A1 between Humans and Rats
    Hiromi Hamamoto, Tatsuya Kusudo, Naoko Urushino, Hiroyuki Masuno, Keiko Yamamoto, Sachiko Yamada, Masaki Kamakura, Miho Ohta, Kuniyo Inouye and Toshiyuki Sakaki
    Molecular Pharmacology July 2006, 70 (1) 120-128; DOI: https://doi.org/10.1124/mol.106.023275
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    Novel α1-Adrenergic Receptor Signaling Pathways: Secreted Factors and Interactions with the Extracellular Matrix
    Ting Shi, Zhong-Hui Duan, Robert Papay, Elzbieta Pluskota, Robert J. Gaivin, Carol A. de la Motte, Edward F. Plow and Dianne M. Perez
    Molecular Pharmacology July 2006, 70 (1) 129-142; DOI: https://doi.org/10.1124/mol.105.020735
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    Comparative Study of ortho- and meta-Nitrated Inhibitors of Catechol-O-methyltransferase: Interactions with the Active Site and Regioselectivity of O-Methylation
    P. N. Palma, M. L. Rodrigues, M. Archer, M. J. Bonifácio, A. I. Loureiro, D. A. Learmonth, M. A. Carrondo and P. Soares-da-Silva
    Molecular Pharmacology July 2006, 70 (1) 143-153; DOI: https://doi.org/10.1124/mol.106.023119
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    Estrogens Cross-Talk to α1b-Adrenergic Receptors
    Aliesha González-Arenas, Beatriz Aguilar-Maldonado, S. Eréndira Avendaño-Vázquez and J. Adolfo García-Sáinz
    Molecular Pharmacology July 2006, 70 (1) 154-162; DOI: https://doi.org/10.1124/mol.106.025064
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    Sustained Aryl Hydrocarbon Receptor Activity Attenuates Liver Regeneration
    Kristen A. Mitchell, Courtney A. Lockhart, Gengming Huang and Cornelis J. Elferink
    Molecular Pharmacology July 2006, 70 (1) 163-170; DOI: https://doi.org/10.1124/mol.106.023465
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    ZIP8, Member of the Solute-Carrier-39 (SLC39) Metal-Transporter Family: Characterization of Transporter Properties
    Lei He, Kuppuswami Girijashanker, Timothy P. Dalton, Jodie Reed, Hong Li, Manoocher Soleimani and Daniel W. Nebert
    Molecular Pharmacology July 2006, 70 (1) 171-180; DOI: https://doi.org/10.1124/mol.106.024521
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    Allosteric Interactions with Muscarinic Acetylcholine Receptors: Complex Role of the Conserved Tryptophan M2422Trp in a Critical Cluster of Amino Acids for Baseline Affinity, Subtype Selectivity, and Cooperativity
    Stefanie Prilla, Jasmin Schrobang, John Ellis, Hans-Dieter Höltje and Klaus Mohr
    Molecular Pharmacology July 2006, 70 (1) 181-193; DOI: https://doi.org/10.1124/mol.106.023481
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    Analysis of G Protein βγ Dimer Formation in Live Cells Using Multicolor Bimolecular Fluorescence Complementation Demonstrates Preferences of β1 for Particular γ Subunits
    Stacy M. Mervine, Evan A. Yost, Jonathan L. Sabo, Thomas R. Hynes and Catherine H. Berlot
    Molecular Pharmacology July 2006, 70 (1) 194-205; DOI: https://doi.org/10.1124/mol.106.022616
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    Possible Endogenous Agonist Mechanism for the Activation of Secretin Family G Protein-Coupled Receptors
    Maoqing Dong, Delia I. Pinon, Yan W. Asmann and Laurence J. Miller
    Molecular Pharmacology July 2006, 70 (1) 206-213; DOI: https://doi.org/10.1124/mol.105.021840
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    Relaxin Family Peptide Receptors RXFP1 and RXFP2 Modulate cAMP Signaling by Distinct Mechanisms
    Michelle L. Halls, Ross A. D. Bathgate and Roger J. Summers
    Molecular Pharmacology July 2006, 70 (1) 214-226; DOI: https://doi.org/10.1124/mol.105.021691
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    Untranslated Region-Dependent Exclusive Expression of High-Sensitivity Subforms of α4β2 and α3β2 Nicotinic Acetylcholine Receptors
    Clark A. Briggs, Earl J. Gubbins, Michael J. Marks, C. Brent Putman, Rama Thimmapaya, Michael D. Meyer and Carol S. Surowy
    Molecular Pharmacology July 2006, 70 (1) 227-240; DOI: https://doi.org/10.1124/mol.105.020198
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    Serum Amyloid A Induces Contrary Immune Responses via Formyl Peptide Receptor-Like 1 in Human Monocytes
    Ha Young Lee, Mi-Kyoung Kim, Kyoung Sun Park, Eun Ha Shin, Seong Ho Jo, Sang Doo Kim, Eun Jin Jo, Youl-Nam Lee, Chuhee Lee, Suk-Hwan Baek and Yoe-Sik Bae
    Molecular Pharmacology July 2006, 70 (1) 241-248; DOI: https://doi.org/10.1124/mol.105.022103
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    Soluble Mimics of the Cytoplasmic Face of the Human V1-Vascular Vasopressin Receptor Bind Arrestin2 and Calmodulin
    Nan Wu, Rosemarie Macion-Dazard, Stanley Nithianantham, Zhen Xu, Susan M. Hanson, Sergey A. Vishnivetskiy, Vsevolod V. Gurevich, Marc Thibonnier and Menachem Shoham
    Molecular Pharmacology July 2006, 70 (1) 249-258; DOI: https://doi.org/10.1124/mol.105.018804
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    Structural Determinants of 4-Chloro-m-cresol Required for Activation of Ryanodine Receptor Type 1
    Alan R. Jacobson, Scott T. Moe, P. D. Allen and James D. Fessenden
    Molecular Pharmacology July 2006, 70 (1) 259-266; DOI: https://doi.org/10.1124/mol.106.022491
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    The Promoter Region of the MDR1 Gene Is Largely Invariant, but Different Single Nucleotide Polymorphism Haplotypes Affect MDR1 Promoter Activity Differently in Different Cell Lines
    Baoshuang Wang, Soomun Ngoi, Jingbo Wang, Samuel S. Chong and Caroline G. L. Lee
    Molecular Pharmacology July 2006, 70 (1) 267-276; DOI: https://doi.org/10.1124/mol.105.019810
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    Chemical Inducers of Rodent Glutathione S-Transferases Down-Regulate Human GSTA1 Transcription through a Mechanism Involving Variant Hepatic Nuclear Factor 1-C
    Laura Romero, Lorraine Ng and Gordon M. Kirby
    Molecular Pharmacology July 2006, 70 (1) 277-286; DOI: https://doi.org/10.1124/mol.105.018622
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    Functional Validation of the Genetic Polymorphisms of Human ATP-Binding Cassette (ABC) Transporter ABCG2: Identification of Alleles That Are Defective in Porphyrin Transport
    Ai Tamura, Masato Watanabe, Hikaru Saito, Hiroshi Nakagawa, Toshiaki Kamachi, Ichiro Okura and Toshihisa Ishikawa
    Molecular Pharmacology July 2006, 70 (1) 287-296; DOI: https://doi.org/10.1124/mol.106.023556
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    Specific Rescue of Cystic Fibrosis Transmembrane Conductance Regulator Processing Mutants Using Pharmacological Chaperones
    Ying Wang, M. Claire Bartlett, Tip W. Loo and David M. Clarke
    Molecular Pharmacology July 2006, 70 (1) 297-302; DOI: https://doi.org/10.1124/mol.106.023994
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    The Role of Human Nucleoside Transporters in Cellular Uptake of 4′-Thio-β-d-arabinofuranosylcytosine and β-d-Arabinosylcytosine
    Marilyn L. Clarke, Vijaya L. Damaraju, Jing Zhang, Delores Mowles, Tracey Tackaberry, Thach Lang, Kyla M. Smith, James D. Young, Blake Tomkinson and Carol E. Cass
    Molecular Pharmacology July 2006, 70 (1) 303-310; DOI: https://doi.org/10.1124/mol.105.021543
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    Direct Modulation of Phospholipase D Activity by Gβγ
    A. M. Preininger, L. G. Henage, W. M. Oldham, E. J. Yoon, H. E. Hamm and H. A. Brown
    Molecular Pharmacology July 2006, 70 (1) 311-318; DOI: https://doi.org/10.1124/mol.105.021451
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    Retinoic Acids Increase P2X2 Receptor Expression through the 5′-Flanking Region of P2rx2 Gene in Rat Phaeochromocytoma PC-12 Cells
    Hidetoshi Tozaki-Saitoh, Schuichi Koizumi, Yoji Sato, Makoto Tsuda, Taku Nagao and Kazuhide Inoue
    Molecular Pharmacology July 2006, 70 (1) 319-328; DOI: https://doi.org/10.1124/mol.105.020511
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    Ketoconazole and Miconazole Are Antagonists of the Human Glucocorticoid Receptor: Consequences on the Expression and Function of the Constitutive Androstane Receptor and the Pregnane X Receptor
    Cedric Duret, Martine Daujat-Chavanieu, Jean-Marc Pascussi, Lydiane Pichard-Garcia, Patrick Balaguer, Jean-Michel Fabre, Marie-José Vilarem, Patrick Maurel and Sabine Gerbal-Chaloin
    Molecular Pharmacology July 2006, 70 (1) 329-339; DOI: https://doi.org/10.1124/mol.105.022046
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    Subtype Specificity of Scorpion β-Toxin Tz1 Interaction with Voltage-Gated Sodium Channels Is Determined by the Pore Loop of Domain 3
    Enrico Leipold, Alfred Hansel, Adolfo Borges and Stefan H. Heinemann
    Molecular Pharmacology July 2006, 70 (1) 340-347; DOI: https://doi.org/10.1124/mol.106.024034
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    Modification and Uptake of a Cisplatin Carbonato Complex by Jurkat Cells
    Corey R. Centerwall, Kirk A. Tacka, Deborah J. Kerwood, Jerry Goodisman, Bonnie B. Toms, Ronald L. Dubowy and James C. Dabrowiak
    Molecular Pharmacology July 2006, 70 (1) 348-355; DOI: https://doi.org/10.1124/mol.106.023184
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    Transfection of Drug-Specific T-Cell Receptors into Hybridoma Cells: Tools to Monitor Drug Interaction with T-Cell Receptors and Evaluate Cross-Reactivity to Related Compounds
    Daphné Anne Schmid, Jan Paul Heribert Depta, Michael Lüthi and Werner Joseph Pichler
    Molecular Pharmacology July 2006, 70 (1) 356-365; DOI: https://doi.org/10.1124/mol.105.021576
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    Inhibition of Human Tyrosyl-DNA Phosphodiesterase by Aminoglycoside Antibiotics and Ribosome Inhibitors
    Zhiyong Liao, Laurent Thibaut, Andrew Jobson and Yves Pommier
    Molecular Pharmacology July 2006, 70 (1) 366-372; DOI: https://doi.org/10.1124/mol.105.021865
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    Experimental and Modeling Studies of Desensitization of P2X3 Receptors
    Elena Sokolova, Andrei Skorinkin, Igor Moiseev, Andrei Agrachev, Andrea Nistri and Rashid Giniatullin
    Molecular Pharmacology July 2006, 70 (1) 373-382; DOI: https://doi.org/10.1124/mol.106.023564
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    Reducing and Oxidizing Agents Sensitize Heat-Activated Vanilloid Receptor (TRPV1) Current
    Klara Susankova, Karolina Tousova, Ladislav Vyklicky, Jan Teisinger and Viktorie Vlachova
    Molecular Pharmacology July 2006, 70 (1) 383-394; DOI: https://doi.org/10.1124/mol.106.023069
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    Neuroprotective Effects of 17β-Estradiol and Nonfeminizing Estrogens against H2O2 Toxicity in Human Neuroblastoma SK-N-SH Cells
    Xiaofei Wang, James A. Dykens, Evelyn Perez, Ran Liu, Shaohua Yang, Douglas F. Covey and James W. Simpkins
    Molecular Pharmacology July 2006, 70 (1) 395-404; DOI: https://doi.org/10.1124/mol.106.022384
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    Potent Modulation of the Voltage-Gated Sodium Channel Nav1.7 by OD1, a Toxin from the Scorpion Odonthobuthus doriae
    Chantal Maertens, Eva Cuypers, Mehriar Amininasab, Amir Jalali, Hossein Vatanpour and Jan Tytgat
    Molecular Pharmacology July 2006, 70 (1) 405-414; DOI: https://doi.org/10.1124/mol.106.022970
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    Peroxisome Proliferator-Activated Receptor-γ and Retinoic Acid X Receptor α Represses the TGFβ1 Gene via PTEN-Mediated p70 Ribosomal S6 Kinase-1 Inhibition: Role for Zf9 Dephosphorylation
    Seung Jin Lee, Eun Kyoung Yang and Sang Geon Kim
    Molecular Pharmacology July 2006, 70 (1) 415-425; DOI: https://doi.org/10.1124/mol.106.022954
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    A Boronic-Chalcone Derivative Exhibits Potent Anticancer Activity through Inhibition of the Proteasome
    Geetha Achanta, Aneta Modzelewska, Li Feng, Saeed R. Khan and Peng Huang
    Molecular Pharmacology July 2006, 70 (1) 426-433; DOI: https://doi.org/10.1124/mol.105.021311

Errata

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    Correction to “No Nitric Oxide for HO-1 from Sodium Nitroprusside”
    Molecular Pharmacology July 2006, 70 (1) 434; DOI: https://doi.org/10.1124/mol.70.1.434
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    Correction to “Positive Inter-Regulation between β-Catenin/T Cell Factor-4 Signaling and Endothelin-1 Signaling Potentiates Proliferation and Survival of Prostate Cancer Cells”
    Molecular Pharmacology July 2006, 70 (1) 435; DOI: https://doi.org/10.1124/mol.70.1.435
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Molecular Pharmacology: 70 (1)
Molecular Pharmacology
Vol. 70, Issue 1
1 Jul 2006
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