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Research ArticleArticle

OSU-03012 Promotes Caspase-Independent but PERK-, Cathepsin B-, BID-, and AIF-Dependent Killing of Transformed Cells

Adly Yacoub, Margaret A. Park, David Hanna, Young Hong, Clint Mitchell, Aditi P. Pandya, Hisashi Harada, Garth Powis, Ching-Shih Chen, Costas Koumenis, Steven Grant and Paul Dent
Molecular Pharmacology August 2006, 70 (2) 589-603; DOI: https://doi.org/10.1124/mol.106.025007
Adly Yacoub
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Margaret A. Park
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David Hanna
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Young Hong
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Clint Mitchell
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Aditi P. Pandya
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Hisashi Harada
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Garth Powis
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Ching-Shih Chen
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Costas Koumenis
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Steven Grant
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Paul Dent
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Article Information

vol. 70 no. 2 589-603
DOI 
https://doi.org/10.1124/mol.106.025007
PubMed 
16622074

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received March 28, 2006
  • Accepted April 18, 2006
  • Published online July 18, 2006.

Article Versions

  • Earlier version (April 18, 2006 - 12:23).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Adly Yacoub,
  2. Margaret A. Park,
  3. David Hanna,
  4. Young Hong,
  5. Clint Mitchell,
  6. Aditi P. Pandya,
  7. Hisashi Harada,
  8. Garth Powis,
  9. Ching-Shih Chen,
  10. Costas Koumenis,
  11. Steven Grant and
  12. Paul Dent
  1. Departments of Biochemistry (A.Y., M.A.P., D.H., Y.H., C.M., A.P.P., S.G., P.D.), Medicine (H.H., S.G.), and Radiation Oncology (A.Y., P.D.), Virginia Commonwealth University, Richmond, Virginia; Division of Medicinal Chemistry, College of Pharmacy, The Ohio State University, Columbus, Ohio (C.-S.C.); Department of Radiation Oncology, Wake Forest University, Winston Salem, North Carolina (C.K.); and Department of Experimental Therapeutics, M.D. Anderson Cancer Center, Houston, Texas (G.P.)
  1. Address correspondence to:
    Dr. Paul Dent, Department of Biochemistry, Massey Cancer Center Virginia Commonwealth University, Richmond, VA 23298-0058. E-mail: pdent{at}hsc.vcu.edu
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Molecular Pharmacology: 70 (2)
Molecular Pharmacology
Vol. 70, Issue 2
1 Aug 2006
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Research ArticleArticle

OSU-03012 Promotes Caspase-Independent but PERK-, Cathepsin B-, BID-, and AIF-Dependent Killing of Transformed Cells

Adly Yacoub, Margaret A. Park, David Hanna, Young Hong, Clint Mitchell, Aditi P. Pandya, Hisashi Harada, Garth Powis, Ching-Shih Chen, Costas Koumenis, Steven Grant and Paul Dent
Molecular Pharmacology August 1, 2006, 70 (2) 589-603; DOI: https://doi.org/10.1124/mol.106.025007

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Research ArticleArticle

OSU-03012 Promotes Caspase-Independent but PERK-, Cathepsin B-, BID-, and AIF-Dependent Killing of Transformed Cells

Adly Yacoub, Margaret A. Park, David Hanna, Young Hong, Clint Mitchell, Aditi P. Pandya, Hisashi Harada, Garth Powis, Ching-Shih Chen, Costas Koumenis, Steven Grant and Paul Dent
Molecular Pharmacology August 1, 2006, 70 (2) 589-603; DOI: https://doi.org/10.1124/mol.106.025007
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