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Research ArticleArticle

Validation of the Anti-Inflammatory Properties of Small-Molecule IκB Kinase (IKK)-2 Inhibitors by Comparison with Adenoviral-Mediated Delivery of Dominant-Negative IKK1 and IKK2 in Human Airways Smooth Muscle

Matthew C. Catley, Maria B. Sukkar, K. Fan Chung, Bruce Jaffee, Sha-Mei Liao, Anthony J. Coyle, El-Bdaoui Haddad, Peter J. Barnes and Robert Newton
Molecular Pharmacology August 2006, 70 (2) 697-705; DOI: https://doi.org/10.1124/mol.106.023150

Article Information

vol. 70 no. 2 697-705
DOI 
https://doi.org/10.1124/mol.106.023150
PubMed 
16687566
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received February 2, 2006
  • Accepted May 8, 2006
  • Published online July 18, 2006.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Matthew C. Catley,
  2. Maria B. Sukkar,
  3. K. Fan Chung,
  4. Bruce Jaffee,
  5. Sha-Mei Liao,
  6. Anthony J. Coyle,
  7. El-Bdaoui Haddad,
  8. Peter J. Barnes and
  9. Robert Newton
  1. National Heart & Lung Institute, Imperial College London, London, United Kingdom (M.C.C., M.B.S., K.F.C., P.J.B.); Millennium Pharmaceuticals Inc., Cambridge, Massachusetts (B.J., S.-M.L., A.J.C.); Sanofi Aventis, Bridgewater, New Jersey (E.-B.H.); and Respiratory Research Group, Department of Cell Biology and Anatomy, University of Calgary, Calgary, Alberta, Canada (R.N.)
  1. Address correspondence to:
    Dr. Robert Newton, Department of Cell Biology and Anatomy, Respiratory Research Group, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, Canada T2N 4N1. E-mail: rnewton{at}ucalgary.ca
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Research ArticleArticle

Validation of the Anti-Inflammatory Properties of Small-Molecule IκB Kinase (IKK)-2 Inhibitors by Comparison with Adenoviral-Mediated Delivery of Dominant-Negative IKK1 and IKK2 in Human Airways Smooth Muscle

Matthew C. Catley, Maria B. Sukkar, K. Fan Chung, Bruce Jaffee, Sha-Mei Liao, Anthony J. Coyle, El-Bdaoui Haddad, Peter J. Barnes and Robert Newton
Molecular Pharmacology August 1, 2006, 70 (2) 697-705; DOI: https://doi.org/10.1124/mol.106.023150
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