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Molecular Pharmacology

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Table of Contents

April 01, 2007; Volume 71,Issue 4

Perspective

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    Constitutive Trafficking—More Than Just Running in Circles?
    Laura M. Bohn
    Molecular Pharmacology April 2007, 71 (4) 957-958; DOI: https://doi.org/10.1124/mol.107.034223

MINIREVIEW

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    The Highly Conserved DRY Motif of Class A G Protein-Coupled Receptors: Beyond the Ground State
    G. Enrico Rovati, Valérie Capra and Richard R. Neubig
    Molecular Pharmacology April 2007, 71 (4) 959-964; DOI: https://doi.org/10.1124/mol.106.029470

Articles

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    Concurrent Administration of Neu2000 and Lithium Produces Marked Improvement of Motor Neuron Survival, Motor Function, and Mortality in a Mouse Model of Amyotrophic Lateral Sclerosis
    Jin Hee Shin, Sung Ig Cho, Hyang Ran Lim, Jae Keun Lee, Young Ae Lee, Jai Sung Noh, In Soo Joo, Kee-Won Kim and Byoung Joo Gwag
    Molecular Pharmacology April 2007, 71 (4) 965-975; DOI: https://doi.org/10.1124/mol.106.030676
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    An Essential Role for Constitutive Endocytosis, but Not Activity, in the Axonal Targeting of the CB1 Cannabinoid Receptor
    Neil A. McDonald, Christopher M. Henstridge, Christopher N. Connolly and Andrew J. Irving
    Molecular Pharmacology April 2007, 71 (4) 976-984; DOI: https://doi.org/10.1124/mol.106.029348
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    Genetic Evidence for a Protective Role of Heat Shock Factor 1 against Irritant-Induced Gastric Lesions
    Ken-ichiro Tanaka, Shinji Tsutsumi, Yasuhiro Arai, Tatsuya Hoshino, Keitarou Suzuki, Eiichi Takaki, Takaaki Ito, Koji Takeuchi, Akira Nakai and Tohru Mizushima
    Molecular Pharmacology April 2007, 71 (4) 985-993; DOI: https://doi.org/10.1124/mol.106.033282
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    Uncovering the Pharmacology of the G Protein-Coupled Receptor GPR40: High Apparent Constitutive Activity in Guanosine 5′-O-(3-[35S]thio)triphosphate Binding Studies Reflects Binding of an Endogenous Agonist
    Leigh A. Stoddart, Andrew J. Brown and Graeme Milligan
    Molecular Pharmacology April 2007, 71 (4) 994-1005; DOI: https://doi.org/10.1124/mol.106.031534
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    Differential Selection of Acridine Resistance Mutations in Human DNA Topoisomerase IIβ Is Dependent on the Acridine Structure
    Chrysoula Leontiou, Gary P. Watters, Kathryn L. Gilroy, Pauline Heslop, Ian G. Cowell, Kate Craig, Robert N. Lightowlers, Jeremy H. Lakey and Caroline A. Austin
    Molecular Pharmacology April 2007, 71 (4) 1006-1014; DOI: https://doi.org/10.1124/mol.106.032953
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    The α1b-Adrenoceptor Exists as a Higher-Order Oligomer: Effective Oligomerization Is Required for Receptor Maturation, Surface Delivery, and Function
    Juan F. Lopez-Gimenez, Meritxell Canals, John D. Pediani and Graeme Milligan
    Molecular Pharmacology April 2007, 71 (4) 1015-1029; DOI: https://doi.org/10.1124/mol.106.033035
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    RGS4 Modulates Serotonin Signaling in Prefrontal Cortex and Links to Serotonin Dysfunction in a Rat Model of Schizophrenia
    Zhenglin Gu, Qian Jiang and Zhen Yan
    Molecular Pharmacology April 2007, 71 (4) 1030-1039; DOI: https://doi.org/10.1124/mol.106.032490
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    N-Terminal Residues Control Proteasomal Degradation of RGS2, RGS4, and RGS5 in Human Embryonic Kidney 293 Cells
    Johannes Bodenstein, Roger K. Sunahara and Richard R. Neubig
    Molecular Pharmacology April 2007, 71 (4) 1040-1050; DOI: https://doi.org/10.1124/mol.106.029397
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    BRCA1 Contributes to Cell Cycle Arrest and Chemoresistance in Response to the Anticancer Agent Irofulven
    Timothy Wiltshire, Jamie Senft, Yutian Wang, Gregory W. Konat, Sharon L. Wenger, Eddie Reed and Weixin Wang
    Molecular Pharmacology April 2007, 71 (4) 1051-1060; DOI: https://doi.org/10.1124/mol.106.029504
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    High-Throughput Screening for Small-Molecule Activators of Neutrophils: Identification of Novel N-Formyl Peptide Receptor Agonists
    Igor A. Schepetkin, Liliya N. Kirpotina, Andrei I. Khlebnikov and Mark T. Quinn
    Molecular Pharmacology April 2007, 71 (4) 1061-1074; DOI: https://doi.org/10.1124/mol.106.033100
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    Voltage-Sensitive Oxonol Dyes Are Novel Large-Conductance Ca2+-Activated K+ Channel Activators Selective for β1 and β4 but Not for β2 Subunits
    Takashi Morimoto, Kazuho Sakamoto, Hiroko Sade, Susumu Ohya, Katsuhiko Muraki and Yuji Imaizumi
    Molecular Pharmacology April 2007, 71 (4) 1075-1088; DOI: https://doi.org/10.1124/mol.106.031146
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    Function of Both Sinusoidal and Canalicular Transporters Controls the Concentration of Organic Anions within Hepatocytes
    Corinne Planchamp, Antoine Hadengue, Bruno Stieger, Joëlle Bourquin, Alain Vonlaufen, Jean-Louis Frossard, Rafael Quadri, Christoph D. Becker and Catherine M. Pastor
    Molecular Pharmacology April 2007, 71 (4) 1089-1097; DOI: https://doi.org/10.1124/mol.106.030759
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    Loss of the High-Affinity Pentamidine Transporter Is Responsible for High Levels of Cross-Resistance between Arsenical and Diamidine Drugs in African Trypanosomes
    Daniel J. Bridges, Matthew K. Gould, Barbara Nerima, Pascal Mäser, Richard J. S. Burchmore and Harry P. de Koning
    Molecular Pharmacology April 2007, 71 (4) 1098-1108; DOI: https://doi.org/10.1124/mol.106.031351
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    Methylmercury-Induced Increase of Intracellular Ca2+ Increases Spontaneous Synaptic Current Frequency in Rat Cerebellar Slices
    Yukun Yuan and William D. Atchison
    Molecular Pharmacology April 2007, 71 (4) 1109-1121; DOI: https://doi.org/10.1124/mol.106.031286
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    Conjugated Bile Acids Regulate Hepatocyte Glycogen Synthase Activity In Vitro and In Vivo via Gαi Signaling
    Youwen Fang, Elaine Studer, Clint Mitchell, Steven Grant, William M. Pandak, Philip B. Hylemon and Paul Dent
    Molecular Pharmacology April 2007, 71 (4) 1122-1128; DOI: https://doi.org/10.1124/mol.106.032060
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    Protein Kinase C-Dependent Mitochondrial Translocation of Proapoptotic Protein Bax on Activation of Inducible Nitric-Oxide Synthase in Rostral Ventrolateral Medulla Mediates Cardiovascular Depression during Experimental Endotoxemia
    Julie Y. H. Chan, Alice Y. W. Chang, Ling-Lin Wang, Chen-Chun Ou and Samuel H. H. Chan
    Molecular Pharmacology April 2007, 71 (4) 1129-1139; DOI: https://doi.org/10.1124/mol.106.031161
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    Structure-Based Identification of Novel Human γ-Glutamylcysteine Synthetase Inhibitors
    David Hamilton, Jian Hui Wu and Gerald Batist
    Molecular Pharmacology April 2007, 71 (4) 1140-1147; DOI: https://doi.org/10.1124/mol.106.024778
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    In Vivo Regulation of Homer1a Expression in the Striatum by Cocaine
    Guo-Chi Zhang, Li-Min Mao, Xian-Yu Liu, Nikhil K. Parelkar, Anish Arora, Lu Yang, Michelle Hains, Eugene E. Fibuch and John Q. Wang
    Molecular Pharmacology April 2007, 71 (4) 1148-1158; DOI: https://doi.org/10.1124/mol.106.028399
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    Activation of cAMP-Dependent Signaling Pathway Induces Mouse Organic Anion Transporting Polypeptide 2 Expression
    Chuan Chen, Xingguo Cheng, Matthew Z. Dieter, Yuji Tanaka and Curtis D. Klaassen
    Molecular Pharmacology April 2007, 71 (4) 1159-1164; DOI: https://doi.org/10.1124/mol.106.030841
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    Structure of the d(CGCGAATTCGCG)2 Complex of the Minor Groove Binding Alkylating Agent Alkamin Studied by Mass Spectrometry
    Amin M. S. Abdul Majid, George Smythe, William A. Denny and Laurence P. G. Wakelin
    Molecular Pharmacology April 2007, 71 (4) 1165-1178; DOI: https://doi.org/10.1124/mol.106.030072
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    Interaction of Gαq and Kir3, G Protein-Coupled Inwardly Rectifying Potassium Channels
    Takeharu Kawano, Peng Zhao, Christina V. Floreani, Yasuko Nakajima, Tohru Kozasa and Shigehiro Nakajima
    Molecular Pharmacology April 2007, 71 (4) 1179-1184; DOI: https://doi.org/10.1124/mol.106.032508
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In this issue

Molecular Pharmacology: 71 (4)
Molecular Pharmacology
Vol. 71, Issue 4
1 Apr 2007
  • Table of Contents
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  • Back Matter (PDF)
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  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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