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Molecular Pharmacology

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Table of Contents

May 01, 2007; Volume 71,Issue 5

MINIREVIEW

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    Vitamin E Analogs, a Novel Group of “Mitocans,” as Anticancer Agents: The Importance of Being Redox-Silent
    Jiri Neuzil, Marco Tomasetti, Yan Zhao, Lan-Feng Dong, Marc Birringer, Xiu-Fang Wang, Pauline Low, Kun Wu, Brian A. Salvatore and Steven J. Ralph
    Molecular Pharmacology May 2007, 71 (5) 1185-1199; DOI: https://doi.org/10.1124/mol.106.030122

Perspectives

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    Missing Links: Mechanisms of Protean Agonism
    Richard R. Neubig
    Molecular Pharmacology May 2007, 71 (5) 1200-1202; DOI: https://doi.org/10.1124/mol.107.034926
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    The Thrill Can Kill: Murder by Methylation
    Sailen Barik
    Molecular Pharmacology May 2007, 71 (5) 1203-1205; DOI: https://doi.org/10.1124/mol.107.035196
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    All Aglow about Presynaptic Receptor Regulation of Neurotransmitter Transporters
    Randy D. Blakely and Louis J. DeFelice
    Molecular Pharmacology May 2007, 71 (5) 1206-1208; DOI: https://doi.org/10.1124/mol.107.035493

Accelerated Communications

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    Activation of TRPA1 Channels by the Fatty Acid Amide Hydrolase Inhibitor 3′-Carbamoylbiphenyl-3-yl cyclohexylcarbamate (URB597)
    Wende Niforatos, Xu-Feng Zhang, Marc R. Lake, Karl A. Walter, Torben Neelands, Thomas F. Holzman, Victoria E. Scott, Connie R. Faltynek, Robert B. Moreland and Jun Chen
    Molecular Pharmacology May 2007, 71 (5) 1209-1216; DOI: https://doi.org/10.1124/mol.106.033621
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    Extracellular Signal-Regulated Kinase Is an Endogenous Signal Retaining the Nuclear Constitutive Active/Androstane Receptor (CAR) in the Cytoplasm of Mouse Primary Hepatocytes
    Chika Koike, Rick Moore and Masahiko Negishi
    Molecular Pharmacology May 2007, 71 (5) 1217-1221; DOI: https://doi.org/10.1124/mol.107.034538

Articles

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    D2 Receptors Regulate Dopamine Transporter Function via an Extracellular Signal-Regulated Kinases 1 and 2-Dependent and Phosphoinositide 3 Kinase-Independent Mechanism
    Elizabeth A. Bolan, Bronwyn Kivell, Vanaja Jaligam, Murat Oz, Lankupalle D. Jayanthi, Yang Han, Namita Sen, Eneki Urizar, Ivone Gomes, Lakshmi A. Devi, Sammanda Ramamoorthy, Jonathan A. Javitch, Agustin Zapata and Toni S. Shippenberg
    Molecular Pharmacology May 2007, 71 (5) 1222-1232; DOI: https://doi.org/10.1124/mol.106.027763
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    Reversal of Stathmin-Mediated Resistance to Paclitaxel and Vinblastine in Human Breast Carcinoma Cells
    Elizabeth Alli, Jin-Ming Yang, James M. Ford and William N. Hait
    Molecular Pharmacology May 2007, 71 (5) 1233-1240; DOI: https://doi.org/10.1124/mol.106.029702
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    Solute-Inhibitor Interactions in the Plasmodial Surface Anion Channel Reveal Complexities in the Transport Process
    Godfrey Lisk, Seth Scott, Tsione Solomon, Ajay D. Pillai and Sanjay A. Desai
    Molecular Pharmacology May 2007, 71 (5) 1241-1250; DOI: https://doi.org/10.1124/mol.106.030734
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    A Widely Used Retinoic Acid Receptor Antagonist Induces Peroxisome Proliferator-Activated Receptor-γ Activity
    Michael Schupp, Joshua C. Curtin, Roy J. Kim, Andrew N. Billin and Mitchell A. Lazar
    Molecular Pharmacology May 2007, 71 (5) 1251-1257; DOI: https://doi.org/10.1124/mol.106.033662
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    Synergistic Neuroprotection by Bis(7)-tacrine via Concurrent Blockade of N-Methyl-d-aspartate Receptors and Neuronal Nitric-Oxide Synthase
    Wenming Li, Jian Xue, Chunying Niu, Hongjun Fu, Colin S. C. Lam, Jialie Luo, Hugh H. N. Chan, Huaiguo Xue, Kelvin K. W. Kan, Nelson T. K. Lee, Chaoying Li, Yuanping Pang, Mingtao Li, Karl W. K. Tsim, Hualiang Jiang, Kaixian Chen, Xiaoyuan Li and Yifan Han
    Molecular Pharmacology May 2007, 71 (5) 1258-1267; DOI: https://doi.org/10.1124/mol.106.029108
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    Domains Necessary for Gα12 Binding and Stimulation of Protein Phosphatase-2A (PP2A): Is Gα12 a Novel Regulatory Subunit of PP2A?
    Deguang Zhu, Robert I. Tate, Ralf Ruediger, Thomas E. Meigs and Bradley M. Denker
    Molecular Pharmacology May 2007, 71 (5) 1268-1276; DOI: https://doi.org/10.1124/mol.106.033555
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    Insulin Increases the Potency of Glycine at Ionotropic Glycine Receptors
    Valerie B. Caraiscos, Robert P. Bonin, J. Glen Newell, Elzbieta Czerwinska, John F. Macdonald and Beverley A. Orser
    Molecular Pharmacology May 2007, 71 (5) 1277-1287; DOI: https://doi.org/10.1124/mol.106.033563
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    Analogs of Methyllycaconitine as Novel Noncompetitive Inhibitors of Nicotinic Receptors: Pharmacological Characterization, Computational Modeling, and Pharmacophore Development
    Dennis B. McKay, Cheng Chang, Tatiana F. González-Cestari, Susan B. McKay, Raed A. El-Hajj, Darrell L. Bryant, Michael X. Zhu, Peter W. Swaan, Kristjan M. Arason, Aravinda B. Pulipaka, Crina M. Orac and Stephen C. Bergmeier
    Molecular Pharmacology May 2007, 71 (5) 1288-1297; DOI: https://doi.org/10.1124/mol.106.033233
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    Vitamin D3 Derivatives with Adamantane or Lactone Ring Side Chains are Cell Type-Selective Vitamin D Receptor Modulators
    Yuka Inaba, Keiko Yamamoto, Nobuko Yoshimoto, Manabu Matsunawa, Shigeyuki Uno, Sachiko Yamada and Makoto Makishima
    Molecular Pharmacology May 2007, 71 (5) 1298-1311; DOI: https://doi.org/10.1124/mol.106.032318
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    Agonist-Driven Conformational Changes in the Inner β-Sheet of α7 Nicotinic Receptors
    James T. McLaughlin, Jie Fu and Robert L. Rosenberg
    Molecular Pharmacology May 2007, 71 (5) 1312-1318; DOI: https://doi.org/10.1124/mol.106.033092
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    Maternal Cocaine Administration Causes an Epigenetic Modification of Protein Kinase Cϵ Gene Expression in Fetal Rat Heart
    Haitao Zhang, Agus Darwanto, Thomas A. Linkhart, Lawrence C. Sowers and Lubo Zhang
    Molecular Pharmacology May 2007, 71 (5) 1319-1328; DOI: https://doi.org/10.1124/mol.106.032011
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    Real-Time Analysis of Agonist-Induced Activation of Protease-Activated Receptor 1/Gαi1 Protein Complex Measured by Bioluminescence Resonance Energy Transfer in Living Cells
    Mohammed A. Ayoub, Damien Maurel, Virginie Binet, Michel Fink, Laurent Prézeau, Hervé Ansanay and Jean-Philippe Pin
    Molecular Pharmacology May 2007, 71 (5) 1329-1340; DOI: https://doi.org/10.1124/mol.106.030304
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    Conformationally Sensitive Reactivity to Permeant Sulfhydryl Reagents of Cysteine Residues Engineered into Helical Hairpin 1 of the Glutamate Transporter GLT-1
    Irina Shlaifer and Baruch I. Kanner
    Molecular Pharmacology May 2007, 71 (5) 1341-1348; DOI: https://doi.org/10.1124/mol.106.032607
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    Protean Agonism at the Dopamine D2 Receptor: (S)-3-(3-Hydroxyphenyl)-N-propylpiperidine Is an Agonist for Activation of Go1 but an Antagonist/Inverse Agonist for Gi1,Gi2, and Gi3
    J. Robert Lane, Ben Powney, Alan Wise, Steven Rees and Graeme Milligan
    Molecular Pharmacology May 2007, 71 (5) 1349-1359; DOI: https://doi.org/10.1124/mol.106.032722
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    Identification of a Second Blocker Binding Site at the Cytoplasmic Mouth of the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Pore
    Chantal N. St. Aubin, Jing-Jun Zhou and Paul Linsdell
    Molecular Pharmacology May 2007, 71 (5) 1360-1368; DOI: https://doi.org/10.1124/mol.106.031732
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    Molecular Signalling Mediating the Protective Effect of A1 Adenosine and mGlu3 Metabotropic Glutamate Receptor Activation against Apoptosis by Oxygen/Glucose Deprivation in Cultured Astrocytes
    Renata Ciccarelli, Iolanda D'Alimonte, Patrizia Ballerini, Mariagrazia D'Auro, Eleonora Nargi, Silvana Buccella, Patrizia Di Iorio, Valeria Bruno, Ferdinando Nicoletti and Francesco Caciagli
    Molecular Pharmacology May 2007, 71 (5) 1369-1380; DOI: https://doi.org/10.1124/mol.106.031617
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    A Critical Role of Luteolin-Induced Reactive Oxygen Species in Blockage of Tumor Necrosis Factor-Activated Nuclear Factor-κB Pathway and Sensitization of Apoptosis in Lung Cancer Cells
    Wei Ju, Xia Wang, Honglian Shi, Wenshu Chen, Steven A. Belinsky and Yong Lin
    Molecular Pharmacology May 2007, 71 (5) 1381-1388; DOI: https://doi.org/10.1124/mol.106.032185
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    Interaction of Novel Positive Allosteric Modulators of Metabotropic Glutamate Receptor 5 with the Negative Allosteric Antagonist Site Is Required for Potentiation of Receptor Responses
    Yelin Chen, Yi Nong, Cyril Goudet, Kamondanai Hemstapat, Tomas de Paulis, Jean-Philippe Pin and P. Jeffrey Conn
    Molecular Pharmacology May 2007, 71 (5) 1389-1398; DOI: https://doi.org/10.1124/mol.106.032425
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    PAR1, but Not PAR4, Activates Human Platelets through a Gi/o/Phosphoinositide-3 Kinase Signaling Axis
    Bryan Voss, Joseph N. McLaughlin, Michael Holinstat, Roy Zent and Heidi E. Hamm
    Molecular Pharmacology May 2007, 71 (5) 1399-1406; DOI: https://doi.org/10.1124/mol.106.033365
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    Activation of Single Nicotinic Receptor Channels from Caenorhabditis elegans Muscle
    Diego Rayes, Marina Flamini, Guillermina Hernando and Cecilia Bouzat
    Molecular Pharmacology May 2007, 71 (5) 1407-1415; DOI: https://doi.org/10.1124/mol.106.033514
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    Quantitative Evaluation of Human δ Opioid Receptor Desensitization Using the Operational Model of Drug Action
    Edita Navratilova, Sue Waite, Dagmar Stropova, Miriam C. Eaton, Isabel D. Alves, Victor J. Hruby, William R. Roeske, Henry I. Yamamura and Eva V. Varga
    Molecular Pharmacology May 2007, 71 (5) 1416-1426; DOI: https://doi.org/10.1124/mol.106.030023
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    Post-Transcriptional Regulation of Human Inducible Nitric-Oxide Synthase Expression by the Jun N-terminal Kinase
    Riku Korhonen, Katrin Linker, Andrea Pautz, Ulrich Förstermann, Eeva Moilanen and Hartmut Kleinert
    Molecular Pharmacology May 2007, 71 (5) 1427-1434; DOI: https://doi.org/10.1124/mol.106.033449
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    Antiproliferative Mechanisms of a Transcription Factor Decoy Targeting Signal Transducer and Activator of Transcription (STAT) 3: The Role of STAT1
    Vivian Wai Yan Lui, Amanda L. Boehm, Priya Koppikar, Rebecca J. Leeman, Daniel Johnson, Michelene Ogagan, Erin Childs, Maria Freilino and Jennifer Rubin Grandis
    Molecular Pharmacology May 2007, 71 (5) 1435-1443; DOI: https://doi.org/10.1124/mol.106.032284
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    Correction to “A Pair-Feeding Study Reveals That a Y5 Antagonist Causes Weight Loss in Diet-Induced Obese Mice by Modulating Food Intake and Energy Expenditure”
    Molecular Pharmacology May 2007, 71 (5) 1444; DOI: https://doi.org/10.1124/mol.71.5.1444
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In this issue

Molecular Pharmacology: 71 (5)
Molecular Pharmacology
Vol. 71, Issue 5
1 May 2007
  • Table of Contents
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  • About the Cover
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  • Back Matter (PDF)
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