Table of Contents

Articles

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  Modified Receptor Internalization upon Coexpression of 5-HT_1B Receptor and 5-HT_2B Receptors

  Agnes Janoshazi, Maud Deraet, Jacques Callebert, Vincent Setola, Silke Guenther, Bruno Saubamea, Philippe Manivet, Jean-Marie Launay and Luc Maroteaux

  Molecular Pharmacology June 2007, 71 (6) 1463-1474; DOI: https://doi.org/10.1124/mol.106.032656
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  Induction of Cyp1a1 Is a Nonspecific Biomarker of Aryl Hydrocarbon Receptor Activation: Results of Large Scale Screening of Pharmaceuticals and Toxicants in Vivo and in Vitro

  Wenyue Hu, Claudio Sorrentino, Michael S. Denison, Kyle Kolaja and Mark R. Fielden

  Molecular Pharmacology June 2007, 71 (6) 1475-1486; DOI: https://doi.org/10.1124/mol.106.032748
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  Identification of Essential Histidine and Cysteine Residues of the H⁺/Organic Cation Antiporter Multidrug and Toxin Extrusion (MATE)

  Jun-ichi Asaka, Tomohiro Terada, Masahiro Tsuda, Toshiya Katsura and Ken-ichi Inui

  Molecular Pharmacology June 2007, 71 (6) 1487-1493; DOI: https://doi.org/10.1124/mol.106.032938
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  Interaction and Inhibitory Cross-Talk between Endothelin and ErbB Receptors in the Adult Heart

  Ka Young Chung and Jeffery W. Walker

  Molecular Pharmacology June 2007, 71 (6) 1494-1502; DOI: https://doi.org/10.1124/mol.106.027599
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  Chromanol 293B Binding in KCNQ1 (Kv7.1) Channels Involves Electrostatic Interactions with a Potassium Ion in the Selectivity Filter

  Christian Lerche, Iva Bruhova, Holger Lerche, Klaus Steinmeyer, Aguan D. Wei, Nathalie Strutz-Seebohm, Florian Lang, Andreas E. Busch, Boris S. Zhorov and Guiscard Seebohm

  Molecular Pharmacology June 2007, 71 (6) 1503-1511; DOI: https://doi.org/10.1124/mol.106.031682
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  Mutation Studies of Ser7.39 and Ser2.60 in the Human CB₁ Cannabinoid Receptor: Evidence for a Serine-Induced Bend in CB₁ Transmembrane Helix 7

  Ankur Kapur, Dow P. Hurst, Daniel Fleischer, Rob Whitnell, Ganesh A. Thakur, Alexandros Makriyannis, Patricia H. Reggio and Mary E. Abood

  Molecular Pharmacology June 2007, 71 (6) 1512-1524; DOI: https://doi.org/10.1124/mol.107.034645
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  Proteasome-Regulated ERBB2 and Estrogen Receptor Pathways in Breast Cancer

  Corina Marx, Christina Yau, Surita Banwait, Yamei Zhou, Gary K. Scott, Byron Hann, John W. Park and Christopher C. Benz

  Molecular Pharmacology June 2007, 71 (6) 1525-1534; DOI: https://doi.org/10.1124/mol.107.034090
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  Mechanism of Thiazolidinedione-Dependent Cell Death in Jurkat T Cells

  Mathias Soller, Stefan Dröse, Ulrich Brandt, Bernhard Brüne and Andreas von Knethen

  Molecular Pharmacology June 2007, 71 (6) 1535-1544; DOI: https://doi.org/10.1124/mol.107.034371
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  Selective Activation of Liver X Receptors by Acanthoic Acid-Related Diterpenes

  Paqui G. Traves, Sonsoles Hortelano, Miriam Zeini, Ta-Hsiang Chao, Thanh Lam, Saskia T. Neuteboom, Emmanuel A. Theodorakis, Michael A. Palladino, Antonio Castrillo and Lisardo Bosca

  Molecular Pharmacology June 2007, 71 (6) 1545-1553; DOI: https://doi.org/10.1124/mol.106.031906
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  Phosphatase and Tensin Homolog Deleted on Chromosome 10 Suppression Is an Important Process in Peroxisome Proliferator-Activated Receptor-γ Signaling in Adipocytes and Myotubes

  Ki Young Kim, Hyun Sill Cho, Won Hoon Jung, Sung Soo Kim and Hyae Gyeong Cheon

  Molecular Pharmacology June 2007, 71 (6) 1554-1562; DOI: https://doi.org/10.1124/mol.106.031948
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  Pharmacology of α-Conotoxin MII-Sensitive Subtypes of Nicotinic Acetylcholine Receptors Isolated by Breeding of Null Mutant Mice

  Outi Salminen, Jennifer A. Drapeau, J. Michael McIntosh, Allan C. Collins, Michael J. Marks and Sharon R. Grady

  Molecular Pharmacology June 2007, 71 (6) 1563-1571; DOI: https://doi.org/10.1124/mol.106.031492
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  α_2A Adrenergic Receptor Activation Inhibits Epileptiform Activity in the Rat Hippocampal CA3 Region

  Chris W. D. Jurgens, Hana M. Hammad, Jessica A. Lichter, Sarah J. Boese, Brian W. Nelson, Brianna L. Goldenstein, Kylie L. Davis, Ke Xu, Kristin L. Hillman, James E. Porter and Van A. Doze

  Molecular Pharmacology June 2007, 71 (6) 1572-1581; DOI: https://doi.org/10.1124/mol.106.031773
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  Natural and Enantiomeric Etiocholanolone Interact with Distinct Sites on the Rat α1β2γ2L GABA_A Receptor

  Ping Li, John Bracamontes, Bryson W. Katona, Douglas F. Covey, Joe Henry Steinbach and Gustav Akk

  Molecular Pharmacology June 2007, 71 (6) 1582-1590; DOI: https://doi.org/10.1124/mol.106.033407
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  Involvement of MRP4 (ABCC4) in the Luminal Efflux of Ceftizoxime and Cefazolin in the Kidney

  Lei Ci, Hiroyuki Kusuhara, Masashi Adachi, John D. Schuetz, Kenji Takeuchi and Yuichi Sugiyama

  Molecular Pharmacology June 2007, 71 (6) 1591-1597; DOI: https://doi.org/10.1124/mol.106.031823
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  Involvement of a Dysfunctional Dopamine-D1/N-Methyl-d-aspartate-NR1 and Ca²⁺/Calmodulin-Dependent Protein Kinase II Pathway in the Impairment of Latent Learning in a Model of Schizophrenia Induced by Phencyclidine

  Akihiro Mouri, Yukihiro Noda, Akihiro Noda, Tomonobu Nakamura, Takanobu Tokura, Yoshimitsu Yura, Atsumi Nitta, Hiroshi Furukawa and Toshitaka Nabeshima

  Molecular Pharmacology June 2007, 71 (6) 1598-1609; DOI: https://doi.org/10.1124/mol.106.032961
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  The Kinetics of Inhibition of Human Acetylcholinesterase and Butyrylcholinesterase by Two Series of Novel Carbamates

  Efrat Groner, Yacov Ashani, Donna Schorer-Apelbaum, Jeffrey Sterling, Yaacov Herzig and Marta Weinstock

  Molecular Pharmacology June 2007, 71 (6) 1610-1617; DOI: https://doi.org/10.1124/mol.107.033928
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  The Relaxin Family Peptide Receptor 3 Activates Extracellular Signal-Regulated Kinase 1/2 through a Protein Kinase C-Dependent Mechanism

  Emma T. van der Westhuizen, Tim D. Werry, Patrick M. Sexton and Roger J. Summers

  Molecular Pharmacology June 2007, 71 (6) 1618-1629; DOI: https://doi.org/10.1124/mol.106.032763
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  Identification and Functional Analysis of a Novel Human CYP2E1 Far Upstream Enhancer

  Jeff D. Shadley, Karthika Divakaran, Kimber Munson, Ronald N. Hines, Kirk Douglas and D. Gail McCarver

  Molecular Pharmacology June 2007, 71 (6) 1630-1639; DOI: https://doi.org/10.1124/mol.106.031302
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  Inhibition of Tumor Necrosis Factor-α through Selective Blockade of Pre-mRNA Splicing by Shikonin

  Shao-Chih Chiu and Ning-Sun Yang

  Molecular Pharmacology June 2007, 71 (6) 1640-1645; DOI: https://doi.org/10.1124/mol.106.032821
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  Subunit-Stoichiometric Evidence for Kir6.2 Channel Gating, ATP Binding, and Binding-Gating Coupling

  Runping Wang, Xiaoli Zhang, Ningren Cui, Jianping Wu, Hailan Piao, Xueren Wang, Junda Su and Chun Jiang

  Molecular Pharmacology June 2007, 71 (6) 1646-1656; DOI: https://doi.org/10.1124/mol.106.030528
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  Inhibition of Vascular Endothelial Growth Factor Cotranslational Translocation by the Cyclopeptolide CAM741

  Hanna Harant, Barbara Wolff, Erwin P. Schreiner, Berndt Oberhauser, Lotte Hofer, Nicole Lettner, Sabine Maier, Jan E. de Vries and Ivan J. Lindley

  Molecular Pharmacology June 2007, 71 (6) 1657-1665; DOI: https://doi.org/10.1124/mol.107.034249
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  Gα_q-Mediated Regulation of TASK3 Two-Pore Domain Potassium Channels: The Role of Protein Kinase C

  Emma L. Veale, Louise E. Kennard, Gemma L. Sutton, Georgina MacKenzie, Cristina Sandu and Alistair Mathie

  Molecular Pharmacology June 2007, 71 (6) 1666-1675; DOI: https://doi.org/10.1124/mol.106.033241
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  Quercetin Activates an Angiogenic Pathway, Hypoxia Inducible Factor (HIF)-1-Vascular Endothelial Growth Factor, by Inhibiting HIF-Prolyl Hydroxylase: a Structural Analysis of Quercetin for Inhibiting HIF-Prolyl Hydroxylase

  Hyunchu Jeon, Heejung Kim, Daekyu Choi, Duksoo Kim, Shi-Young Park, Yung-Jin Kim, Young Mi Kim and Yunjin Jung

  Molecular Pharmacology June 2007, 71 (6) 1676-1684; DOI: https://doi.org/10.1124/mol.107.034041
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  The Amine-Containing Cutaneous Irritant Heptylamine Inhibits the Volume-Regulated Anion Channel and Mobilizes Intracellular Calcium in Normal Human Epidermal Keratinocytes

  Matthieu Raoux, Cécile Colomban, Patrick Delmas and Marcel Crest

  Molecular Pharmacology June 2007, 71 (6) 1685-1694; DOI: https://doi.org/10.1124/mol.106.033324
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  The Thiazolidinedione Pioglitazone Alters Mitochondrial Function in Human Neuron-Like Cells

  Sangeeta Ghosh, Nishant Patel, Douglas Rahn, Jenna McAllister, Sina Sadeghi, Geoffrey Horwitz, Diana Berry, Kai Xuan Wang and Russell H. Swerdlow

  Molecular Pharmacology June 2007, 71 (6) 1695-1702; DOI: https://doi.org/10.1124/mol.106.033845
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  Fisetin, an Inhibitor of Cyclin-Dependent Kinase 6, Down-Regulates Nuclear Factor-κB-Regulated Cell Proliferation, Antiapoptotic and Metastatic Gene Products through the Suppression of TAK-1 and Receptor-Interacting Protein-Regulated IκBα Kinase Activation

  Bokyung Sung, Manoj K. Pandey and Bharat B. Aggarwal

  Molecular Pharmacology June 2007, 71 (6) 1703-1714; DOI: https://doi.org/10.1124/mol.107.034512
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  Pioglitazone and Rosiglitazone Decrease Prostaglandin E₂ in Non–Small-Cell Lung Cancer Cells by Up-Regulating 15-Hydroxyprostaglandin Dehydrogenase

  Saswati Hazra, Raj K. Batra, Hsin H. Tai, Sherven Sharma, Xiaoyan Cui and Steven M. Dubinett

  Molecular Pharmacology June 2007, 71 (6) 1715-1720; DOI: https://doi.org/10.1124/mol.106.033357