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Molecular Pharmacology

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Table of Contents

August 01, 2007; Volume 72,Issue 2

MINIREVIEW

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    Receptor-Mediated Activation of Heterotrimeric G-Proteins: Current Structural Insights
    Christopher A. Johnston and David P. Siderovski
    Molecular Pharmacology August 2007, 72 (2) 219-230; DOI: https://doi.org/10.1124/mol.107.034348

Perspectives

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    Challenges and Opportunities of Trapping Ligands
    Mariusz W. Szkudlinski
    Molecular Pharmacology August 2007, 72 (2) 231-234; DOI: https://doi.org/10.1124/mol.107.038208
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    Brain-Derived Neurotrophic Factor: Linking Fear Learning to Memory Consolidation
    Marie-H. Monfils, Kiriana K. Cowansage and Joseph E. LeDoux
    Molecular Pharmacology August 2007, 72 (2) 235-237; DOI: https://doi.org/10.1124/mol.107.038232

Articles

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    Trapping of a Nonpeptide Ligand by the Extracellular Domains of the Gonadotropin-Releasing Hormone Receptor Results in Insurmountable Antagonism
    Trudy A. Kohout, Qiu Xie, Shelby Reijmers, Kenneth J. Finn, Zhiqiang Guo, Yun-Fei Zhu and R. Scott Struthers
    Molecular Pharmacology August 2007, 72 (2) 238-247; DOI: https://doi.org/10.1124/mol.107.035535
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    RETRACTION: Erlotinib, an Effective Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Induces p27KIP1 Up-Regulation and Nuclear Translocation in Association with Cell Growth Inhibition and G1/S Phase Arrest in Human Non-Small-Cell Lung Cancer Cell Lines
    Yi-He Ling, Tianhong Li, Ziqiang Yuan, Missak Haigentz, Thomas K. Weber and Roman Perez-Soler
    Molecular Pharmacology August 2007, 72 (2) 248-258; DOI: https://doi.org/10.1124/mol.107.034827
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    APETx1 from Sea Anemone Anthopleura elegantissima Is a Gating Modifier Peptide Toxin of the Human Ether-a-go-go- Related Potassium Channel
    M. Zhang, X.-S. Liu, S. Diochot, M. Lazdunski and G.-N. Tseng
    Molecular Pharmacology August 2007, 72 (2) 259-268; DOI: https://doi.org/10.1124/mol.107.035840
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    UR-1505, a New Salicylate, Blocks T Cell Activation through Nuclear Factor of Activated T Cells
    Juan Román, Alberto Fernández de Arriba, Sonia Barrón, Pedro Michelena, Marta Giral, Manuel Merlos, Elvira Bailón, Mònica Comalada, Julio Gálvez, Antonio Zarzuelo and Isabel Ramis
    Molecular Pharmacology August 2007, 72 (2) 269-279; DOI: https://doi.org/10.1124/mol.107.035212
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    Molecular Approximations between Residues 21 and 23 of Secretin and Its Receptor: Development of a Model for Peptide Docking with the Amino Terminus of the Secretin Receptor
    Maoqing Dong, Polo C.-H. Lam, Fan Gao, Keiko Hosohata, Delia I. Pinon, Patrick M. Sexton, Ruben Abagyan and Laurence J. Miller
    Molecular Pharmacology August 2007, 72 (2) 280-290; DOI: https://doi.org/10.1124/mol.107.035402
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    A Novel Multivalent Ligand That Bridges the Allosteric and Orthosteric Binding Sites of the M2 Muscarinic Receptor
    Tod Steinfeld, Mathai Mammen, Jacqueline A. M. Smith, Richard D. Wilson and Jeffrey R. Jasper
    Molecular Pharmacology August 2007, 72 (2) 291-302; DOI: https://doi.org/10.1124/mol.106.033746
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    Bradykinin-Induced Nuclear Factor of Activated T-Cells-Dependent Transcription in Rat Dorsal Root Ganglion Neurons
    Joshua G. Jackson, Yuriy M. Usachev and Stanley A. Thayer
    Molecular Pharmacology August 2007, 72 (2) 303-310; DOI: https://doi.org/10.1124/mol.107.035048
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    Novel Stable Camptothecin Derivatives Replacing the E-Ring Lactone by a Ketone Function Are Potent Inhibitors of Topoisomerase I and Promising Antitumor Drugs
    Amélie Lansiaux, Stéphane Léonce, Laurence Kraus-Berthier, Christine Bal-Mahieu, Romain Mazinghien, Sébastien Didier, Marie-Hélène David-Cordonnier, Patrick Hautefaye, Gilbert Lavielle, Christian Bailly, John A. Hickman and Alain Pierré
    Molecular Pharmacology August 2007, 72 (2) 311-319; DOI: https://doi.org/10.1124/mol.107.034637
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    Characterization of an NBS1 C-Terminal Peptide That Can Inhibit Ataxia Telangiectasia Mutated (ATM)-Mediated DNA Damage Responses and Enhance Radiosensitivity
    Mickael J. Cariveau, Xi Tang, Xiao-Li Cui and Bo Xu
    Molecular Pharmacology August 2007, 72 (2) 320-326; DOI: https://doi.org/10.1124/mol.107.036681
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    Molecular Interaction of a Potent Nonpeptide Agonist with the Chemokine Receptor CCR8
    Pia C. Jensen, Rie Nygaard, Stefanie Thiele, Amy Elder, Guoming Zhu, Roland Kolbeck, Shomir Ghosh, Thue W. Schwartz and Mette M. Rosenkilde
    Molecular Pharmacology August 2007, 72 (2) 327-340; DOI: https://doi.org/10.1124/mol.107.035543
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    Critical Role for Sphingosine Kinase-1 in Regulating Survival of Neuroblastoma Cells Exposed to Amyloid-β Peptide
    Anne Gomez-Brouchet, Dimitri Pchejetski, Leyre Brizuela, Virginie Garcia, Marie-Françoise Altié, Marie-Lise Maddelein, Marie-Bernadette Delisle and Olivier Cuvillier
    Molecular Pharmacology August 2007, 72 (2) 341-349; DOI: https://doi.org/10.1124/mol.106.033738
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    Transcriptional Regulation of Brain-Derived Neurotrophic Factor in the Amygdala during Consolidation of Fear Memory
    Li-Chin Ou and Po-Wu Gean
    Molecular Pharmacology August 2007, 72 (2) 350-358; DOI: https://doi.org/10.1124/mol.107.034934
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    β1 (KCNMB1) Subunits Mediate Lithocholate Activation of Large-Conductance Ca2+-Activated K+ Channels and Dilation in Small, Resistance-Size Arteries
    Anna N. Bukiya, Jianxi Liu, Ligia Toro and Alejandro M. Dopico
    Molecular Pharmacology August 2007, 72 (2) 359-369; DOI: https://doi.org/10.1124/mol.107.034330
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    5-Androstenediol Promotes Survival of γ-Irradiated Human Hematopoietic Progenitors through Induction of Nuclear Factor-κB Activation and Granulocyte Colony-Stimulating Factor Expression
    Mang Xiao, Cynthia E. Inal, Vaishali I. Parekh, Cheng-Min Chang and Mark H. Whitnall
    Molecular Pharmacology August 2007, 72 (2) 370-379; DOI: https://doi.org/10.1124/mol.107.035394
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    Identification of the Atypical L-Type Ca2+ Channel Blocker Diltiazem and Its Metabolites As Ghrelin Receptor Agonists
    Jian-Nong Ma, Hans H. Schiffer, Anne E. Knapp, Jean Wang, Kenneth K. Wong, Erika A. Currier, Michelle Owens, Norman R. Nash, Luis R. Gardell, Mark R. Brann, Roger Olsson and Ethan S. Burstein
    Molecular Pharmacology August 2007, 72 (2) 380-386; DOI: https://doi.org/10.1124/mol.107.034298
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    Multidrug Resistance Proteins 2 and 3 Provide Alternative Routes for Hepatic Excretion of Morphine-Glucuronides
    Koen van de Wetering, Noam Zelcer, Annemieke Kuil, Wouter Feddema, Michel Hillebrand, Maria L. H. Vlaming, Alfred H. Schinkel, Jos H. Beijnen and Piet Borst
    Molecular Pharmacology August 2007, 72 (2) 387-394; DOI: https://doi.org/10.1124/mol.107.035592
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    Caffeine Inhibits Adenosine-Induced Accumulation of Hypoxia-Inducible Factor-1α, Vascular Endothelial Growth Factor, and Interleukin-8 Expression in Hypoxic Human Colon Cancer Cells
    Stefania Merighi, Annalisa Benini, Prisco Mirandola, Stefania Gessi, Katia Varani, Carolina Simioni, Edward Leung, Stephen Maclennan, Pier Giovanni Baraldi and Pier Andrea Borea
    Molecular Pharmacology August 2007, 72 (2) 395-406; DOI: https://doi.org/10.1124/mol.106.032920
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    Glitazones Induce Astroglioma Cell Death by Releasing Reactive Oxygen Species from Mitochondria: Modulation of Cytotoxicity by Nitric Oxide
    José M. Pérez-Ortiz, Pedro Tranque, Miguel Burgos, Cecilia F. Vaquero and Juan Llopis
    Molecular Pharmacology August 2007, 72 (2) 407-417; DOI: https://doi.org/10.1124/mol.106.032458
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    Suppression of Osteoclastogenesis by N,N-Dimethyl-D-erythro-sphingosine: A Sphingosine Kinase Inhibition-Independent Action
    Hyung Joon Kim, Youngkyun Lee, Eun-Ju Chang, Hyun-Man Kim, Sam-Pyo Hong, Zang Hee Lee, Jiyoon Ryu and Hong-Hee Kim
    Molecular Pharmacology August 2007, 72 (2) 418-428; DOI: https://doi.org/10.1124/mol.107.034173
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    N-Ethylmaleimide-Sensitive Factor Regulates β2 Adrenoceptor Trafficking and Signaling in Cardiomyocytes
    Yongyu Wang, Benjamin Lauffer, Mark Von Zastrow, Brian K. Kobilka and Yang Xiang
    Molecular Pharmacology August 2007, 72 (2) 429-439; DOI: https://doi.org/10.1124/mol.107.037747
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    Inhibition of Hypoxia-Induced Increase of Blood-Brain Barrier Permeability by YC-1 through the Antagonism of HIF-1α Accumulation and VEGF Expression
    Wei-Lan Yeh, Dah-Yuu Lu, Chun-Jung Lin, Houng-Chi Liou and Wen-Mei Fu
    Molecular Pharmacology August 2007, 72 (2) 440-449; DOI: https://doi.org/10.1124/mol.107.036418
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    Desensitization of the Dopamine D1 and D2 Receptor Hetero-Oligomer Mediated Calcium Signal by Agonist Occupancy of Either Receptor
    Christopher H. So, Vaneeta Verma, Brian F. O'Dowd and Susan R. George
    Molecular Pharmacology August 2007, 72 (2) 450-462; DOI: https://doi.org/10.1124/mol.107.034884
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    Structure-Function Studies of Allosteric Agonism at M2 Muscarinic Acetylcholine Receptors
    Lauren T. May, Vimesh A. Avlani, Christopher J. Langmead, Hugh J. Herdon, Martyn D. Wood, Patrick M. Sexton and Arthur Christopoulos
    Molecular Pharmacology August 2007, 72 (2) 463-476; DOI: https://doi.org/10.1124/mol.107.037630
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    A Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 2 Blocks a Hallucinogenic Drug Model of Psychosis
    Michael A. Benneyworth, Zixiu Xiang, Randy L. Smith, Efrain E. Garcia, P. Jeffrey Conn and Elaine Sanders-Bush
    Molecular Pharmacology August 2007, 72 (2) 477-484; DOI: https://doi.org/10.1124/mol.107.035170

Errata

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    Correction to “Structure of the d(CGCGAATTCGCG)2 Complex of the Minor Groove Binding Alkylating Agent Alkamin Studied by Mass Spectrometry”
    Molecular Pharmacology August 2007, 72 (2) 485; DOI: https://doi.org/10.1124/mol.72.2.485
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    Correction to “Development of a Novel Nitro-Derivative of Noscapine for the Potential Treatment of Drug-Resistant Ovarian Cancer and T-Cell Lymphoma”
    Molecular Pharmacology August 2007, 72 (2) 486; DOI: https://doi.org/10.1124/mol.72.2.486
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Molecular Pharmacology: 72 (2)
Molecular Pharmacology
Vol. 72, Issue 2
1 Aug 2007
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