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Research ArticleArticle

Critical Role for Sphingosine Kinase-1 in Regulating Survival of Neuroblastoma Cells Exposed to Amyloid-β Peptide

Anne Gomez-Brouchet, Dimitri Pchejetski, Leyre Brizuela, Virginie Garcia, Marie-Françoise Altié, Marie-Lise Maddelein, Marie-Bernadette Delisle and Olivier Cuvillier
Molecular Pharmacology August 2007, 72 (2) 341-349; DOI: https://doi.org/10.1124/mol.106.033738
Anne Gomez-Brouchet
Institut National de la Santé et de la Recherche Médicale U466, Toulouse, France (A.G.-B., D.P., V.G., M.-F.A., M.-B.D., O.C.); Université Toulouse III Paul Sabatier, Toulouse, France (A.G.-B., D.P., L.B., V.G., M.-F.A., M.-L.M., M.-B.D., O.C.); Centre Hospitalier Universitaire Toulouse, Service d'Anatomie et de Cytologie Pathologiques, Toulouse, France (A.G.-B., M.-B.D.); and Centre National de la Recherche Scientifique, Institut de Pharmacologie et de Biologie Structurale, Unité Mixte de Recherche 5089, Toulouse, France (D.P., L.B., M.-L.M., O.C.)
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Dimitri Pchejetski
Institut National de la Santé et de la Recherche Médicale U466, Toulouse, France (A.G.-B., D.P., V.G., M.-F.A., M.-B.D., O.C.); Université Toulouse III Paul Sabatier, Toulouse, France (A.G.-B., D.P., L.B., V.G., M.-F.A., M.-L.M., M.-B.D., O.C.); Centre Hospitalier Universitaire Toulouse, Service d'Anatomie et de Cytologie Pathologiques, Toulouse, France (A.G.-B., M.-B.D.); and Centre National de la Recherche Scientifique, Institut de Pharmacologie et de Biologie Structurale, Unité Mixte de Recherche 5089, Toulouse, France (D.P., L.B., M.-L.M., O.C.)
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Leyre Brizuela
Institut National de la Santé et de la Recherche Médicale U466, Toulouse, France (A.G.-B., D.P., V.G., M.-F.A., M.-B.D., O.C.); Université Toulouse III Paul Sabatier, Toulouse, France (A.G.-B., D.P., L.B., V.G., M.-F.A., M.-L.M., M.-B.D., O.C.); Centre Hospitalier Universitaire Toulouse, Service d'Anatomie et de Cytologie Pathologiques, Toulouse, France (A.G.-B., M.-B.D.); and Centre National de la Recherche Scientifique, Institut de Pharmacologie et de Biologie Structurale, Unité Mixte de Recherche 5089, Toulouse, France (D.P., L.B., M.-L.M., O.C.)
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Virginie Garcia
Institut National de la Santé et de la Recherche Médicale U466, Toulouse, France (A.G.-B., D.P., V.G., M.-F.A., M.-B.D., O.C.); Université Toulouse III Paul Sabatier, Toulouse, France (A.G.-B., D.P., L.B., V.G., M.-F.A., M.-L.M., M.-B.D., O.C.); Centre Hospitalier Universitaire Toulouse, Service d'Anatomie et de Cytologie Pathologiques, Toulouse, France (A.G.-B., M.-B.D.); and Centre National de la Recherche Scientifique, Institut de Pharmacologie et de Biologie Structurale, Unité Mixte de Recherche 5089, Toulouse, France (D.P., L.B., M.-L.M., O.C.)
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Marie-Françoise Altié
Institut National de la Santé et de la Recherche Médicale U466, Toulouse, France (A.G.-B., D.P., V.G., M.-F.A., M.-B.D., O.C.); Université Toulouse III Paul Sabatier, Toulouse, France (A.G.-B., D.P., L.B., V.G., M.-F.A., M.-L.M., M.-B.D., O.C.); Centre Hospitalier Universitaire Toulouse, Service d'Anatomie et de Cytologie Pathologiques, Toulouse, France (A.G.-B., M.-B.D.); and Centre National de la Recherche Scientifique, Institut de Pharmacologie et de Biologie Structurale, Unité Mixte de Recherche 5089, Toulouse, France (D.P., L.B., M.-L.M., O.C.)
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Marie-Lise Maddelein
Institut National de la Santé et de la Recherche Médicale U466, Toulouse, France (A.G.-B., D.P., V.G., M.-F.A., M.-B.D., O.C.); Université Toulouse III Paul Sabatier, Toulouse, France (A.G.-B., D.P., L.B., V.G., M.-F.A., M.-L.M., M.-B.D., O.C.); Centre Hospitalier Universitaire Toulouse, Service d'Anatomie et de Cytologie Pathologiques, Toulouse, France (A.G.-B., M.-B.D.); and Centre National de la Recherche Scientifique, Institut de Pharmacologie et de Biologie Structurale, Unité Mixte de Recherche 5089, Toulouse, France (D.P., L.B., M.-L.M., O.C.)
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Marie-Bernadette Delisle
Institut National de la Santé et de la Recherche Médicale U466, Toulouse, France (A.G.-B., D.P., V.G., M.-F.A., M.-B.D., O.C.); Université Toulouse III Paul Sabatier, Toulouse, France (A.G.-B., D.P., L.B., V.G., M.-F.A., M.-L.M., M.-B.D., O.C.); Centre Hospitalier Universitaire Toulouse, Service d'Anatomie et de Cytologie Pathologiques, Toulouse, France (A.G.-B., M.-B.D.); and Centre National de la Recherche Scientifique, Institut de Pharmacologie et de Biologie Structurale, Unité Mixte de Recherche 5089, Toulouse, France (D.P., L.B., M.-L.M., O.C.)
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Olivier Cuvillier
Institut National de la Santé et de la Recherche Médicale U466, Toulouse, France (A.G.-B., D.P., V.G., M.-F.A., M.-B.D., O.C.); Université Toulouse III Paul Sabatier, Toulouse, France (A.G.-B., D.P., L.B., V.G., M.-F.A., M.-L.M., M.-B.D., O.C.); Centre Hospitalier Universitaire Toulouse, Service d'Anatomie et de Cytologie Pathologiques, Toulouse, France (A.G.-B., M.-B.D.); and Centre National de la Recherche Scientifique, Institut de Pharmacologie et de Biologie Structurale, Unité Mixte de Recherche 5089, Toulouse, France (D.P., L.B., M.-L.M., O.C.)
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Article Information

vol. 72 no. 2 341-349
DOI 
https://doi.org/10.1124/mol.106.033738
PubMed 
17522181

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received December 22, 2006
  • Accepted May 22, 2007
  • Published online July 24, 2007.

Article Versions

  • Earlier version (May 23, 2007 - 07:28).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Anne Gomez-Brouchet,
  2. Dimitri Pchejetski,
  3. Leyre Brizuela,
  4. Virginie Garcia,
  5. Marie-Françoise Altié,
  6. Marie-Lise Maddelein,
  7. Marie-Bernadette Delisle, and
  8. Olivier Cuvillier
  1. Institut National de la Santé et de la Recherche Médicale U466, Toulouse, France (A.G.-B., D.P., V.G., M.-F.A., M.-B.D., O.C.); Université Toulouse III Paul Sabatier, Toulouse, France (A.G.-B., D.P., L.B., V.G., M.-F.A., M.-L.M., M.-B.D., O.C.); Centre Hospitalier Universitaire Toulouse, Service d'Anatomie et de Cytologie Pathologiques, Toulouse, France (A.G.-B., M.-B.D.); and Centre National de la Recherche Scientifique, Institut de Pharmacologie et de Biologie Structurale, Unité Mixte de Recherche 5089, Toulouse, France (D.P., L.B., M.-L.M., O.C.)
  1. Address correspondence to:
    Dr Olivier Cuvillier, Institut de Pharmacologie et de Biologie Structurale, CNRS UMR 5089, 31077 Toulouse Cedex 4, France. E-mail: olivier.cuvillier{at}ipbs.fr
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Molecular Pharmacology: 72 (2)
Molecular Pharmacology
Vol. 72, Issue 2
1 Aug 2007
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Research ArticleArticle

Critical Role for Sphingosine Kinase-1 in Regulating Survival of Neuroblastoma Cells Exposed to Amyloid-β Peptide

Anne Gomez-Brouchet, Dimitri Pchejetski, Leyre Brizuela, Virginie Garcia, Marie-Françoise Altié, Marie-Lise Maddelein, Marie-Bernadette Delisle and Olivier Cuvillier
Molecular Pharmacology August 1, 2007, 72 (2) 341-349; DOI: https://doi.org/10.1124/mol.106.033738

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Research ArticleArticle

Critical Role for Sphingosine Kinase-1 in Regulating Survival of Neuroblastoma Cells Exposed to Amyloid-β Peptide

Anne Gomez-Brouchet, Dimitri Pchejetski, Leyre Brizuela, Virginie Garcia, Marie-Françoise Altié, Marie-Lise Maddelein, Marie-Bernadette Delisle and Olivier Cuvillier
Molecular Pharmacology August 1, 2007, 72 (2) 341-349; DOI: https://doi.org/10.1124/mol.106.033738
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