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Constitutively Active Mutants of the Histamine H1 Receptor Suggest a Conserved Hydrophobic Asparagine-Cage That Constrains the Activation of Class A G Protein-Coupled Receptors

Remko A. Bakker, Aldo Jongejan, Kamonchanok Sansuk, Uli Hacksell, Henk Timmerman, Mark R. Brann, Dave M. Weiner, Leonardo Pardo and Rob Leurs
Molecular Pharmacology January 2008, 73 (1) 94-103; DOI: https://doi.org/10.1124/mol.107.038547
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Research ArticleArticle

Constitutively Active Mutants of the Histamine H1 Receptor Suggest a Conserved Hydrophobic Asparagine-Cage That Constrains the Activation of Class A G Protein-Coupled Receptors

Remko A. Bakker, Aldo Jongejan, Kamonchanok Sansuk, Uli Hacksell, Henk Timmerman, Mark R. Brann, Dave M. Weiner, Leonardo Pardo and Rob Leurs
Molecular Pharmacology January 1, 2008, 73 (1) 94-103; DOI: https://doi.org/10.1124/mol.107.038547
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