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Molecular Pharmacology

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Table of Contents

February 01, 2008; Volume 73,Issue 2

Perspective

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    Revoking the Privilege: Targeting HER2 in the Central Nervous System
    Joseph N. Contessa and Daniel A. Hamstra
    Molecular Pharmacology February 2008, 73 (2) 271-273; DOI: https://doi.org/10.1124/mol.107.042986

Accelerated Communication

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    Prostaglandin-Induced Activation of Nociceptive Neurons via Direct Interaction with Transient Receptor Potential A1 (TRPA1)
    Thomas E. Taylor-Clark, Bradley J. Undem, Donald W. MacGlashan, Srinivas Ghatta, Michael J. Carr and M. Allen McAlexander
    Molecular Pharmacology February 2008, 73 (2) 274-281; DOI: https://doi.org/10.1124/mol.107.040832

Articles

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    Cortical Glutamatergic Neurons Mediate the Motor Sedative Action of Diazepam
    A. Zeller, F. Crestani, I. Camenisch, T. Iwasato, S. Itohara, J. M. Fritschy and U. Rudolph
    Molecular Pharmacology February 2008, 73 (2) 282-291; DOI: https://doi.org/10.1124/mol.107.038828
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    Distinct Phosphorylation Sites in the SST2A Somatostatin Receptor Control Internalization, Desensitization, and Arrestin Binding
    Q. Liu, D. A. Dewi, W. Liu, M. S. Bee and A. Schonbrunn
    Molecular Pharmacology February 2008, 73 (2) 292-304; DOI: https://doi.org/10.1124/mol.107.038570
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    Conformational Flexibility of Helix VI Is Essential for Substrate Permeation of the Human Apical Sodium-Dependent Bile Acid Transporter
    Naissan Hussainzada, Akash Khandewal and Peter W. Swaan
    Molecular Pharmacology February 2008, 73 (2) 305-313; DOI: https://doi.org/10.1124/mol.107.041640
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    Anandamide Inhibition of 5-HT3A Receptors Varies with Receptor Density and Desensitization
    Wei Xiong, Masako Hosoi, Bon-Nyeo Koo and Li Zhang
    Molecular Pharmacology February 2008, 73 (2) 314-322; DOI: https://doi.org/10.1124/mol.107.039149
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    Peroxisome Proliferator-Activated Receptor-α Contributes to the Anti-Inflammatory Activity of Glucocorticoids
    Salvatore Cuzzocrea, Stefano Bruscoli, Emanuela Mazzon, Concetta Crisafulli, Valerio Donato, Rosanna Di Paola, Enrico Velardi, Emanuela Esposito, Giuseppe Nocentini and Carlo Riccardi
    Molecular Pharmacology February 2008, 73 (2) 323-337; DOI: https://doi.org/10.1124/mol.107.041475
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    Cellular and in Vivo Activity of JNJ-28871063, A Nonquinazoline Pan-ErbB Kinase Inhibitor That Crosses the Blood-Brain Barrier and Displays Efficacy against Intracranial Tumors
    Stuart L. Emanuel, Terry V. Hughes, Mary Adams, Catherine A. Rugg, Angel Fuentes-Pesquera, Peter J. Connolly, Niranjan Pandey, Sandra Moreno-Mazza, Jeannene Butler, Virna Borowski, Steven A. Middleton, Robert H. Gruninger, Jennifer R. Story, Cheryl Napier, Beth Hollister and Lee M. Greenberger
    Molecular Pharmacology February 2008, 73 (2) 338-348; DOI: https://doi.org/10.1124/mol.107.041236
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    Characterization of G-Protein Coupled Receptor Kinase Interaction with the Neurokinin-1 Receptor Using Bioluminescence Resonance Energy Transfer
    Rasmus Jorgensen, Nicholas D. Holliday, Jakob L. Hansen, Milka Vrecl, Anders Heding, Thue W. Schwartz and Christian E. Elling
    Molecular Pharmacology February 2008, 73 (2) 349-358; DOI: https://doi.org/10.1124/mol.107.038877
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    A Novel Actin-Binding Domain on Slo1 Calcium-Activated Potassium Channels Is Necessary for Their Expression in the Plasma Membrane
    Shengwei Zou, Smita Jha, Eun Young Kim and Stuart E. Dryer
    Molecular Pharmacology February 2008, 73 (2) 359-368; DOI: https://doi.org/10.1124/mol.107.039743
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    The β1 Subunit of L-Type Voltage-Gated Ca2+ Channels Independently Binds to and Inhibits the Gating of Large-Conductance Ca2+-Activated K+ Channels
    Shengwei Zou, Smita Jha, Eun Young Kim and Stuart E. Dryer
    Molecular Pharmacology February 2008, 73 (2) 369-378; DOI: https://doi.org/10.1124/mol.107.040733
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    Functional Characterization of a Nucleoside-Derived Drug Transporter Variant (hCNT3C602R) Showing Altered Sodium-Binding Capacity
    Ekaitz Errasti-Murugarren, Pedro Cano-Soldado, Marçal Pastor-Anglada and Fco Javier Casado
    Molecular Pharmacology February 2008, 73 (2) 379-386; DOI: https://doi.org/10.1124/mol.107.041848
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    Repression of Aryl Hydrocarbon Receptor (AHR) Signaling by AHR Repressor: Role of DNA Binding and Competition for AHR Nuclear Translocator
    Brad R. Evans, Sibel I. Karchner, Lenka L. Allan, Richard S. Pollenz, Robert L. Tanguay, Matthew J. Jenny, David H. Sherr and Mark E. Hahn
    Molecular Pharmacology February 2008, 73 (2) 387-398; DOI: https://doi.org/10.1124/mol.107.040204
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    Curcumin Protects the Rat Liver from CCl4-Caused Injury and Fibrogenesis by Attenuating Oxidative Stress and Suppressing Inflammation
    Yumei Fu, Shizhong Zheng, Jianguo Lin, Jan Ryerse and Anping Chen
    Molecular Pharmacology February 2008, 73 (2) 399-409; DOI: https://doi.org/10.1124/mol.107.039818
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    Small Molecule Disruption of G Protein βγ Subunit Signaling Inhibits Neutrophil Chemotaxis and Inflammation
    D. M. Lehmann, A. M. P. B. Seneviratne and A. V. Smrcka
    Molecular Pharmacology February 2008, 73 (2) 410-418; DOI: https://doi.org/10.1124/mol.107.041780
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    BubR1 Is Required for a Sustained Mitotic Spindle Checkpoint Arrest in Human Cancer Cells Treated with Tubulin-Targeting Pyrrolo-1,5-Benzoxazepines
    Lisa M. Greene, Giuseppe Campiani, Mark Lawler, D. Clive Williams and Daniela M. Zisterer
    Molecular Pharmacology February 2008, 73 (2) 419-430; DOI: https://doi.org/10.1124/mol.107.039024
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    Role of Extracellular Domain Dimerization in Agonist-Induced Activation of Natriuretic Peptide Receptor A
    Marie Parat, Normand McNicoll, Brian Wilkes, Alain Fournier and André De Léan
    Molecular Pharmacology February 2008, 73 (2) 431-440; DOI: https://doi.org/10.1124/mol.107.039982
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    Inhibition of Human Neutrophil Chemotaxis by Endogenous Cannabinoids and Phytocannabinoids: Evidence for a Site Distinct from CB1 and CB2
    Douglas McHugh, Carolyn Tanner, Raphael Mechoulam, Roger G. Pertwee and Ruth A. Ross
    Molecular Pharmacology February 2008, 73 (2) 441-450; DOI: https://doi.org/10.1124/mol.107.041863
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    Dexamethasone-Mediated Up-Regulation of Human CYP2A6 Involves the Glucocorticoid Receptor and Increased Binding of Hepatic Nuclear Factor 4α to the Proximal Promoter
    Tania Onica, Kathleen Nichols, Meghan Larin, Lorraine Ng, Ann Maslen, Zdenek Dvorak, Jean-Marc Pascussi, Marie-Josée Vilarem, Patrick Maurel and Gordon M. Kirby
    Molecular Pharmacology February 2008, 73 (2) 451-460; DOI: https://doi.org/10.1124/mol.107.039354
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    Transport of Cisplatin by the Copper Efflux Transporter ATP7B
    Roohangiz Safaei, Shinji Otani, Barrett J. Larson, Michael L. Rasmussen and Stephen B. Howell
    Molecular Pharmacology February 2008, 73 (2) 461-468; DOI: https://doi.org/10.1124/mol.107.040980
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    Cloning and Functional Expression of a Novel Gi Protein-Coupled Receptor for Adenine from Mouse Brain
    Ivar von Kügelgen, Anke C. Schiedel, Kristina Hoffmann, Bernt B. A. Alsdorf, Aliaa Abdelrahman and Christa E. Müller
    Molecular Pharmacology February 2008, 73 (2) 469-477; DOI: https://doi.org/10.1124/mol.107.037069
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    Structural Analog of Sildenafil Identified as a Novel Corrector of the F508del-CFTR Trafficking Defect
    Renaud Robert, Graeme W. Carlile, Catalin Pavel, Na Liu, Suzana M. Anjos, Jie Liao, Yishan Luo, Donglei Zhang, David Y. Thomas and John W. Hanrahan
    Molecular Pharmacology February 2008, 73 (2) 478-489; DOI: https://doi.org/10.1124/mol.107.040725
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    Reduced Expression of DNA Topoisomerase I in SF295 Human Glioblastoma Cells Selected for Resistance to Homocamptothecin and Diflomotecan
    Zhiyong Liao, Robert W. Robey, Josée Guirouilh-Barbat, Kenneth K. W. To, Orsolya Polgar, Susan E. Bates and Yves Pommier
    Molecular Pharmacology February 2008, 73 (2) 490-497; DOI: https://doi.org/10.1124/mol.107.041178
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    Impact of Targeting the Adenine- and Uracil-Rich Element of bcl-2 mRNA with Oligoribonucleotides on Apoptosis, Cell Cycle, and Neuronal Differentiation in SHSY-5Y Cells
    Laura Papucci, Ewa Witort, Anna Maria Bevilacqua, Martino Donnini, Matteo Lulli, Elisabetta Borchi, Khalid S. A. Khabar, Alessio Tempestini, Andrea Lapucci, Nicola Schiavone, Angelo Nicolin and Sergio Capaccioli
    Molecular Pharmacology February 2008, 73 (2) 498-508; DOI: https://doi.org/10.1124/mol.107.038323
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    A Peroxisome Proliferator-Activated Receptor γ-Retinoid X Receptor Heterodimer Physically Interacts with the Transcriptional Activator PAX6 to Inhibit Glucagon Gene Transcription
    Ralph Krätzner, Florian Fröhlich, Katrin Lepler, Michaela Schröder, Katharina Röher, Corinna Dickel, Mladen V. Tzvetkov, Thomas Quentin, Elke Oetjen and Willhart Knepel
    Molecular Pharmacology February 2008, 73 (2) 509-517; DOI: https://doi.org/10.1124/mol.107.035568
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    [3H]Org 43553, the First Low-Molecular-Weight Agonistic and Allosteric Radioligand for the Human Luteinizing Hormone Receptor
    Laura H. Heitman, Julia Oosterom, Kimberly M. Bonger, Cornelis M. Timmers, Peter H. G. Wiegerinck and Adriaan P. IJzerman
    Molecular Pharmacology February 2008, 73 (2) 518-524; DOI: https://doi.org/10.1124/mol.107.039875
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    Multiple Binding Sites for Substrates and Modulators of Semicarbazide-Sensitive Amine Oxidases: Kinetic Consequences
    Andrew Holt, David J. Smith, Laura Cendron, Giuseppe Zanotti, Adelio Rigo and Maria Luisa Di Paolo
    Molecular Pharmacology February 2008, 73 (2) 525-538; DOI: https://doi.org/10.1124/mol.107.040964
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    Functional Characterization of Bone Morphogenetic Protein Binding Sites and Smad1/5 Activation in Human Vascular Cells
    Paul D. Upton, Lu Long, Richard C. Trembath and Nicholas W. Morrell
    Molecular Pharmacology February 2008, 73 (2) 539-552; DOI: https://doi.org/10.1124/mol.107.041673
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    Methyl 2-Cyano-3,11-dioxo-18β-olean-1,12-dien-30-oate Is a Peroxisome Proliferator-Activated Receptor-γ Agonist That Induces Receptor-Independent Apoptosis in LNCaP Prostate Cancer Cells
    Sabitha Papineni, Sudhakar Chintharlapalli and Stephen Safe
    Molecular Pharmacology February 2008, 73 (2) 553-565; DOI: https://doi.org/10.1124/mol.107.041285
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    Mitogenic Effects of Cytokines on Smooth Muscle Are Critically Dependent on Protein Kinase A and Are Unmasked by Steroids and Cyclooxygenase Inhibitors
    Anna M. Misior, Huandong Yan, Rodolfo M. Pascual, Deepak A. Deshpande, Reynold A. Panettieri and Raymond B. Penn
    Molecular Pharmacology February 2008, 73 (2) 566-574; DOI: https://doi.org/10.1124/mol.107.040519
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    3-Methylcholanthrene Displays Dual Effects on Estrogen Receptor (ER) α and ERβ Signaling in a Cell-Type Specific Fashion
    Elin Swedenborg, Joëlle Rüegg, Anne Hillenweck, Stefan Rehnmark, Malin Hedengran Faulds, Daniel Zalko, Ingemar Pongratz and Katarina Pettersson
    Molecular Pharmacology February 2008, 73 (2) 575-586; DOI: https://doi.org/10.1124/mol.107.036384
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    Regulation of Lysophosphatidic Acid Receptor Expression and Function in Human Synoviocytes: Implications for Rheumatoid Arthritis?
    Chenqi Zhao, Maria J. Fernandes, Glenn D. Prestwich, Mélanie Turgeon, John Di Battista, Timothy Clair, Patrice E. Poubelle and Sylvain G. Bourgoin
    Molecular Pharmacology February 2008, 73 (2) 587-600; DOI: https://doi.org/10.1124/mol.107.038216
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    Efavirenz Accelerates HIV-1 Reverse Transcriptase Ribonuclease H Cleavage, Leading to Diminished Zidovudine Excision
    Jessica Radzio and Nicolas Sluis-Cremer
    Molecular Pharmacology February 2008, 73 (2) 601-606; DOI: https://doi.org/10.1124/mol.107.038596
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    Regulation of Human 3α-Hydroxysteroid Dehydrogenase (AKR1C4) Expression by the Liver X Receptor α
    Keith R. Stayrook, Pamela M. Rogers, Rajesh S. Savkur, Yongjun Wang, Chen Su, Gabor Varga, Xin Bu, Tao Wei, Sunil Nagpal, Xiaole Shirley Liu and Thomas P. Burris
    Molecular Pharmacology February 2008, 73 (2) 607-612; DOI: https://doi.org/10.1124/mol.107.039099
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Molecular Pharmacology: 73 (2)
Molecular Pharmacology
Vol. 73, Issue 2
1 Feb 2008
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