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Research ArticleArticle

A New Mechanism of 6-((2-(Dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno(2,1-c)quinolin-7-one Dihydrochloride (TAS-103) Action Discovered by Target Screening with Drug-Immobilized Affinity Beads

Makoto Yoshida, Yasuaki Kabe, Tadashi Wada, Akira Asai and Hiroshi Handa
Molecular Pharmacology March 2008, 73 (3) 987-994; DOI: https://doi.org/10.1124/mol.107.043307

Article Information

vol. 73 no. 3 987-994
DOI 
https://doi.org/10.1124/mol.107.043307
PubMed 
18089836
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received November 7, 2007
  • Accepted December 18, 2007
  • Published online February 21, 2008.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Makoto Yoshida,
  2. Yasuaki Kabe,
  3. Tadashi Wada,
  4. Akira Asai and
  5. Hiroshi Handa
  1. Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (M.Y.,Y.K.,T.W.,H.H.); Integrated Research Institute Graduate school of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (T.W.,H.H.); and Graduate School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan (A.A.)
  1. Address correspondence to:
    Dr. Hiroshi Handa, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa, 226-8501, Japan. E-mail: hhanda{at}bio.titech.ac.jp
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Research ArticleArticle

A New Mechanism of 6-((2-(Dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno(2,1-c)quinolin-7-one Dihydrochloride (TAS-103) Action Discovered by Target Screening with Drug-Immobilized Affinity Beads

Makoto Yoshida, Yasuaki Kabe, Tadashi Wada, Akira Asai and Hiroshi Handa
Molecular Pharmacology March 1, 2008, 73 (3) 987-994; DOI: https://doi.org/10.1124/mol.107.043307
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