Table of Contents

Articles

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  The Duffy Antigen/Receptor for Chemokines Exists in an Oligomeric Form in Living Cells and Functionally Antagonizes CCR5 Signaling through Hetero-Oligomerization

  Aron Chakera, Ruth M. Seeber, Alison E. John, Karin A. Eidne and David R. Greaves

  Molecular Pharmacology May 2008, 73 (5) 1362-1370; DOI: https://doi.org/10.1124/mol.107.040915
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  Allosteric Ligands for the Corticotropin Releasing Factor Type 1 Receptor Modulate Conformational States Involved in Receptor Activation

  Sam R. J. Hoare, Beth A. Fleck, Raymond S. Gross, Paul D. Crowe, John P. Williams and Dimitri E. Grigoriadis

  Molecular Pharmacology May 2008, 73 (5) 1371-1380; DOI: https://doi.org/10.1124/mol.107.042978
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  Inhibition of Rho Family Functions by Lovastatin Promotes Myelin Repair in Ameliorating Experimental Autoimmune Encephalomyelitis

  Ajaib Singh Paintlia, Manjeet Kaur Paintlia, Avtar Kaur Singh and Inderjit Singh

  Molecular Pharmacology May 2008, 73 (5) 1381-1393; DOI: https://doi.org/10.1124/mol.107.044230
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  Tumor Necrosis Factor-α Regulates Inflammatory and Mesenchymal Responses via Mitogen-Activated Protein Kinase Kinase, p38, and Nuclear Factor κB in Human Endometriotic Epithelial Cells

  Eric M. Grund, David Kagan, Cam Anh Tran, Andreas Zeitvogel, Anna Starzinski-Powitz, Selvaraj Nataraja and Stephen S. Palmer

  Molecular Pharmacology May 2008, 73 (5) 1394-1404; DOI: https://doi.org/10.1124/mol.107.042176
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  Tissue-Specific Regulation of Microvascular Diameter: Opposite Functional Roles of Neuronal and Smooth Muscle Located Vanilloid Receptor-1

  Tamás Kark, Zsolt Bagi, Erzsébet Lizanecz, Enikő T. Pásztor, Nóra Erdei, Ágnes Czikora, Zoltán Papp, István Édes, Róbert Pórszász and Attila Tóth

  Molecular Pharmacology May 2008, 73 (5) 1405-1412; DOI: https://doi.org/10.1124/mol.107.043323
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  Slc39a14 Gene Encodes ZIP14, A Metal/Bicarbonate Symporter: Similarities to the ZIP8 Transporter

  Kuppuswami Girijashanker, Lei He, Manoocher Soleimani, Jodie M. Reed, Hong Li, Zhiwei Liu, Bin Wang, Timothy P. Dalton and Daniel W. Nebert

  Molecular Pharmacology May 2008, 73 (5) 1413-1423; DOI: https://doi.org/10.1124/mol.107.043588
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  Simvastatin Protects against Amyloid β and HIV-1 Tat-Induced Promoter Activities of Inflammatory Genes in Brain Endothelial Cells

  Ibolya E. András, GeunBae Rha, Wen Huang, SungYong Eum, Pierre-Olivier Couraud, Ignacio A. Romero, Bernhard Hennig and Michal Toborek

  Molecular Pharmacology May 2008, 73 (5) 1424-1433; DOI: https://doi.org/10.1124/mol.107.042028
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  In Vivo Imaging Reveals Selective Peroxisome Proliferator Activated Receptor Modulator Activity of the Synthetic Ligand 3-(1-(4-Chlorobenzyl)-3-t-butylthio-5-isopropylindol-2-yl)-2,2-dimethylpropanoic acid (MK-886)

  Andrea Biserni, Fabio Giannessi, Anna Floriana Sciarroni, Ferdinando Maria Milazzo, Adriana Maggi and Paolo Ciana

  Molecular Pharmacology May 2008, 73 (5) 1434-1443; DOI: https://doi.org/10.1124/mol.107.042689
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  Seizure-Induced Up-Regulation of P-Glycoprotein at the Blood-Brain Barrier through Glutamate and Cyclooxygenase-2 Signaling

  Björn Bauer, Anika M. S. Hartz, Anton Pekcec, Kathrin Toellner, David S. Miller and Heidrun Potschka

  Molecular Pharmacology May 2008, 73 (5) 1444-1453; DOI: https://doi.org/10.1124/mol.107.041210
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  Tumor Necrosis Factor-α Enhances Neutrophil Adhesiveness: Induction of Vascular Cell Adhesion Molecule-1 via Activation of Akt and CaM Kinase II and Modifications of Histone Acetyltransferase and Histone Deacetylase 4 in Human Tracheal Smooth Muscle Cells

  Chiang-Wen Lee, Chih-Chung Lin, Shue-Fen Luo, Hui-Chun Lee, I.-Ta Lee, William C. Aird, Tsong-Long Hwang and Chuen-Mao Yang

  Molecular Pharmacology May 2008, 73 (5) 1454-1464; DOI: https://doi.org/10.1124/mol.107.038091
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  Epigallocatechin-3-gallate Inhibits Growth of Activated Hepatic Stellate Cells by Enhancing the Capacity of Glutathione Synthesis

  Yumei Fu, Shizhong Zheng, Shelly C. Lu and Anping Chen

  Molecular Pharmacology May 2008, 73 (5) 1465-1473; DOI: https://doi.org/10.1124/mol.107.040634
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  Involvement of Multiple Efflux Transporters in Hepatic Disposition of Fexofenadine

  Soichiro Matsushima, Kazuya Maeda, Hisamitsu Hayashi, Yasuyuki Debori, Alfred H. Schinkel, John D. Schuetz, Hiroyuki Kusuhara and Yuichi Sugiyama

  Molecular Pharmacology May 2008, 73 (5) 1474-1483; DOI: https://doi.org/10.1124/mol.107.041459
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  Dynamic Regulation of Glutamatergic Postsynaptic Activity in Rat Prefrontal Cortex by Repeated Administration of Antipsychotic Drugs

  Fabio Fumagalli, Angelisa Frasca, Giorgio Racagni and Marco Andrea Riva

  Molecular Pharmacology May 2008, 73 (5) 1484-1490; DOI: https://doi.org/10.1124/mol.107.043786
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  The Chemopreventive Agent Curcumin Is a Potent Radiosensitizer of Human Cervical Tumor Cells via Increased Reactive Oxygen Species Production and Overactivation of the Mitogen-Activated Protein Kinase Pathway

  Prashanthi Javvadi, Andrew T. Segan, Stephen W. Tuttle and Constantinos Koumenis

  Molecular Pharmacology May 2008, 73 (5) 1491-1501; DOI: https://doi.org/10.1124/mol.107.043554
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  Abrogation of Hyperosmotic Impairment of Insulin Signaling by a Novel Class of 1,2-Dithiole-3-thiones through the Inhibition of S6K1 Activation

  Eun Ju Bae, Yoon Mee Yang and Sang Geon Kim

  Molecular Pharmacology May 2008, 73 (5) 1502-1512; DOI: https://doi.org/10.1124/mol.107.044347
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  Translocation of Glycosylphosphatidylinositol-Anchored Proteins from Plasma Membrane Microdomains to Lipid Droplets in Rat Adipocytes Is Induced by Palmitate, H₂O₂, and the Sulfonylurea Drug Glimepiride

  Günter Müller, Susanne Wied, Nicole Walz and Christian Jung

  Molecular Pharmacology May 2008, 73 (5) 1513-1529; DOI: https://doi.org/10.1124/mol.107.043935
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  Interleukin 13 Increases Contractility of Murine Tracheal Smooth Muscle by a Phosphoinositide 3-kinase p110δ-Dependent Mechanism

  Hanan S. M. Farghaly, Ian S. Blagbrough, David A. Medina-Tato and Malcolm L. Watson

  Molecular Pharmacology May 2008, 73 (5) 1530-1537; DOI: https://doi.org/10.1124/mol.108.045419
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  Endogenous Regulators of G Protein Signaling Differentially Modulate Full and Partial μ-Opioid Agonists at Adenylyl Cyclase as Predicted by a Collision Coupling Model

  M. J. Clark, J. J. Linderman and J. R. Traynor

  Molecular Pharmacology May 2008, 73 (5) 1538-1548; DOI: https://doi.org/10.1124/mol.107.043547
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  RETRACTION: Flavopiridol Suppresses Tumor Necrosis Factor-Induced Activation of Activator Protein-1, c-Jun N-Terminal Kinase, p38 Mitogen-Activated Protein Kinase (MAPK), p44/p42 MAPK, and Akt, Inhibits Expression of Antiapoptotic Gene Products, and Enhances Apoptosis through Cytochrome c Release and Caspase Activation in Human Myeloid Cells

  Yasunari Takada, Gautam Sethi, Bokyung Sung and Bharat B. Aggarwal

  Molecular Pharmacology May 2008, 73 (5) 1549-1557; DOI: https://doi.org/10.1124/mol.107.041350
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  Interaction of Heterogeneous Nuclear Ribonucleoprotein C1/C2 with a Novel cis-Regulatory Element within p53 mRNA as a Response to Cytostatic Drug Treatment

  Kyle J. Christian, Matti A. Lang and Françoise Raffalli-Mathieu

  Molecular Pharmacology May 2008, 73 (5) 1558-1567; DOI: https://doi.org/10.1124/mol.107.042507
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  Targeting MDR1 Gene: Synthesis and Cellular Study of Modified Daunomycin-Triplex-Forming Oligonucleotide Conjugates Able to Inhibit Gene Expression in Resistant Cell Lines

  Vérène Stierlé, Maria Duca, Ludovic Halby, Catherine Senamaud-Beaufort, Massimo L. Capobianco, Alain Laigle, Béatrice Jollès and Paola B. Arimondo

  Molecular Pharmacology May 2008, 73 (5) 1568-1577; DOI: https://doi.org/10.1124/mol.107.042010
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  Discovery of a Quorum-Sensing Inhibitor of Drug-Resistant Staphylococcal Infections by Structure-Based Virtual Screening

  Madanahally D. Kiran, Nallini Vijayarangan Adikesavan, Oscar Cirioni, Andrea Giacometti, Carmela Silvestri, Giorgio Scalise, Roberto Ghiselli, Vittorio Saba, Fiorenza Orlando, Menachem Shoham and Naomi Balaban

  Molecular Pharmacology May 2008, 73 (5) 1578-1586; DOI: https://doi.org/10.1124/mol.107.044164