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Research ArticleArticle

Allosteric Ligands for the Corticotropin Releasing Factor Type 1 Receptor Modulate Conformational States Involved in Receptor Activation

Sam R. J. Hoare, Beth A. Fleck, Raymond S. Gross, Paul D. Crowe, John P. Williams and Dimitri E. Grigoriadis
Molecular Pharmacology May 2008, 73 (5) 1371-1380; DOI: https://doi.org/10.1124/mol.107.042978

Article Information

vol. 73 no. 5 1371-1380
DOI 
https://doi.org/10.1124/mol.107.042978
PubMed 
18239030
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received October 26, 2007
  • Accepted January 28, 2008
  • Published online April 16, 2008.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Sam R. J. Hoare,
  2. Beth A. Fleck,
  3. Raymond S. Gross,
  4. Paul D. Crowe,
  5. John P. Williams, and
  6. Dimitri E. Grigoriadis
  1. Emerging Technologies (S.R.J.H., R.S.G, P.D.C, J.P.W, D.E.G.) and Endocrine and Metabolic (B.A.F, D.E.G.) Biomedical Research and Innovative Discovery Groups, Neurocrine Biosciences Inc., San Diego, California
  1. Address correspondence to:
    Dr. Sam R. J. Hoare, Emerging Technologies Biomedical Research and Innovative Discovery Group, Neurocrine Biosciences Inc., 12790 El Camino Real, San Diego, CA 92130. E-mail shoare{at}neurocrine.com
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Research ArticleArticle

Allosteric Ligands for the Corticotropin Releasing Factor Type 1 Receptor Modulate Conformational States Involved in Receptor Activation

Sam R. J. Hoare, Beth A. Fleck, Raymond S. Gross, Paul D. Crowe, John P. Williams and Dimitri E. Grigoriadis
Molecular Pharmacology May 1, 2008, 73 (5) 1371-1380; DOI: https://doi.org/10.1124/mol.107.042978
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