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Research ArticleArticle

The Chemopreventive Agent Curcumin Is a Potent Radiosensitizer of Human Cervical Tumor Cells via Increased Reactive Oxygen Species Production and Overactivation of the Mitogen-Activated Protein Kinase Pathway

Prashanthi Javvadi, Andrew T. Segan, Stephen W. Tuttle and Constantinos Koumenis
Molecular Pharmacology May 2008, 73 (5) 1491-1501; DOI: https://doi.org/10.1124/mol.107.043554

Article Information

vol. 73 no. 5 1491-1501
DOI 
https://doi.org/10.1124/mol.107.043554
PubMed 
18252805
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received November 16, 2007
  • Accepted February 5, 2008
  • Published online April 16, 2008.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Prashanthi Javvadi,
  2. Andrew T. Segan,
  3. Stephen W. Tuttle, and
  4. Constantinos Koumenis
  1. Department of Radiation Oncology (P.J., A.T.S., S.W.T., C.K.) and Program in Cell and Molecular Biology (P.J.), University of Pennsylvania, Philadelphia, Pennsylvania
  1. Address correspondence to:
    Constantinos Koumenis, Department of Radiation Oncology, University of Pennsylvania, 3620 Hamilton Walk, Philadelphia, PA 19104. E-mail: koumenis{at}xrt.upenn.edu
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Research ArticleArticle

The Chemopreventive Agent Curcumin Is a Potent Radiosensitizer of Human Cervical Tumor Cells via Increased Reactive Oxygen Species Production and Overactivation of the Mitogen-Activated Protein Kinase Pathway

Prashanthi Javvadi, Andrew T. Segan, Stephen W. Tuttle and Constantinos Koumenis
Molecular Pharmacology May 1, 2008, 73 (5) 1491-1501; DOI: https://doi.org/10.1124/mol.107.043554
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