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Molecular Pharmacology

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Research ArticleArticle

Amiloride Derivatives and a Nonpeptidic Antagonist Bind at Two Distinct Allosteric Sites in the Human Gonadotropin-Releasing Hormone Receptor

Laura H. Heitman, Kai Ye, Julia Oosterom and Adriaan P. IJzerman
Molecular Pharmacology June 2008, 73 (6) 1808-1815; DOI: https://doi.org/10.1124/mol.107.043521
Laura H. Heitman
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Kai Ye
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Julia Oosterom
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Adriaan P. IJzerman
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Article Information

vol. 73 no. 6 1808-1815
DOI 
https://doi.org/10.1124/mol.107.043521
PubMed 
18344315

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received November 15, 2007
  • Accepted March 14, 2008
  • Published online May 20, 2008.

Article Versions

  • Earlier version (March 14, 2008 - 08:53).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Laura H. Heitman,
  2. Kai Ye,
  3. Julia Oosterom and
  4. Adriaan P. IJzerman
  1. Division of Medicinal Chemistry, Leiden/Amsterdam Center for Drug Research, Leiden University, Leiden, the Netherlands (L.H.H., K.Y., A.P.IJ.); and Pharmacology Department, Organon BioSciences, Oss, The Netherlands (J.O.)
  1. Address correspondence to:
    A. P. IJzerman, Division of Medicinal Chemistry, Leiden/Amsterdam Center for Drug Research, University of Leiden, P.O. Box 9502, 2300 RA Leiden, The Netherlands. E-mail: ijzerman{at}lacdr.leidenuniv.nl
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Molecular Pharmacology: 73 (6)
Molecular Pharmacology
Vol. 73, Issue 6
1 Jun 2008
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Research ArticleArticle

Amiloride Derivatives and a Nonpeptidic Antagonist Bind at Two Distinct Allosteric Sites in the Human Gonadotropin-Releasing Hormone Receptor

Laura H. Heitman, Kai Ye, Julia Oosterom and Adriaan P. IJzerman
Molecular Pharmacology June 1, 2008, 73 (6) 1808-1815; DOI: https://doi.org/10.1124/mol.107.043521

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Research ArticleArticle

Amiloride Derivatives and a Nonpeptidic Antagonist Bind at Two Distinct Allosteric Sites in the Human Gonadotropin-Releasing Hormone Receptor

Laura H. Heitman, Kai Ye, Julia Oosterom and Adriaan P. IJzerman
Molecular Pharmacology June 1, 2008, 73 (6) 1808-1815; DOI: https://doi.org/10.1124/mol.107.043521
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