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Molecular Pharmacology

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Table of Contents

July 01, 2008; Volume 74,Issue 1

Accelerated Communication

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    Atrial Natriuretic Peptide Protects against Histamine-Induced Endothelial Barrier Dysfunction in Vivo
    Robert Fürst, Martin F. Bubik, Peter Bihari, Bettina A. Mayer, Alexander G. Khandoga, Florian Hoffmann, Markus Rehberg, Fritz Krombach, Stefan Zahler and Angelika M. Vollmar
    Molecular Pharmacology July 2008, 74 (1) 1-8; DOI: https://doi.org/10.1124/mol.108.045773

Articles

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    Identification of Regions Required for Apical Membrane Localization of Human Multidrug Resistance Protein 2
    Paul E. Bandler, Christopher J. Westlake, Caroline E. Grant, Susan P. C. Cole and Roger G. Deeley
    Molecular Pharmacology July 2008, 74 (1) 9-19; DOI: https://doi.org/10.1124/mol.108.045674
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    Attenuation of Experimental Autoimmune Hepatitis by Exogenous and Endogenous Cannabinoids: Involvement of Regulatory T Cells
    Venkatesh L. Hegde, Shweta Hegde, Benjamin F. Cravatt, Lorne J. Hofseth, Mitzi Nagarkatti and Prakash S. Nagarkatti
    Molecular Pharmacology July 2008, 74 (1) 20-33; DOI: https://doi.org/10.1124/mol.108.047035
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    Kinetic Characterization and Molecular Docking of a Novel, Potent, and Selective Slow-Binding Inhibitor of Human Cathepsin L
    Parag P. Shah, Michael C. Myers, Mary Pat Beavers, Jeremy E. Purvis, Huiyan Jing, Heather J. Grieser, Elizabeth R. Sharlow, Andrew D. Napper, Donna M. Huryn, Barry S. Cooperman, Amos B. Smith and Scott L. Diamond
    Molecular Pharmacology July 2008, 74 (1) 34-41; DOI: https://doi.org/10.1124/mol.108.046219
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    Niemann-Pick C1-Like 1 Mediates α-Tocopherol Transport
    Kazuya Narushima, Tappei Takada, Yoshihide Yamanashi and Hiroshi Suzuki
    Molecular Pharmacology July 2008, 74 (1) 42-49; DOI: https://doi.org/10.1124/mol.107.043034
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    Molecular Determinants for the Activating/Blocking Actions of the 2H-1,4-Benzoxazine Derivatives, a Class of Potassium Channel Modulators Targeting the Skeletal Muscle KATP Channels
    Domenico Tricarico, Antonietta Mele, Giulia Maria Camerino, Antonio Laghezza, Giuseppe Carbonara, Giuseppe Fracchiolla, Paolo Tortorella, Fulvio Loiodice and Diana Conte Camerino
    Molecular Pharmacology July 2008, 74 (1) 50-58; DOI: https://doi.org/10.1124/mol.108.046615
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    Reciprocal Regulation of Dopamine D1 and D3 Receptor Function and Trafficking by Heterodimerization
    Chiara Fiorentini, Chiara Busi, Emanuela Gorruso, Cecilia Gotti, PierFranco Spano and Cristina Missale
    Molecular Pharmacology July 2008, 74 (1) 59-69; DOI: https://doi.org/10.1124/mol.107.043885
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    Baicalein Induces Functional Hypoxia-Inducible Factor-1α and Angiogenesis
    Hyunju Cho, Ho-Youl Lee, Dae-Ro Ahn, Sang Yoon Kim, Sunyun Kim, Keun Byeol Lee, You Mie Lee, Hyunsung Park and Eun Gyeong Yang
    Molecular Pharmacology July 2008, 74 (1) 70-81; DOI: https://doi.org/10.1124/mol.107.040162
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    Carmustine-Resistant Cancer Cells Are Sensitized to Temozolomide As A Result of Enhanced Mismatch Repair during the Development of Carmustine Resistance
    Takahiro Yamauchi, Masami Ogawa and Takanori Ueda
    Molecular Pharmacology July 2008, 74 (1) 82-91; DOI: https://doi.org/10.1124/mol.107.041988
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    Activation of 9-[(R)-2-[[(S)-[[(S)-1-(Isopropoxycarbonyl)ethyl]amino] phenoxyphosphinyl]-methoxy]propyl]adenine (GS-7340) and Other Tenofovir Phosphonoamidate Prodrugs by Human Proteases
    Gabriel Birkus, Nilima Kutty, Gong-Xin He, Andrew Mulato, William Lee, Martin McDermott and Tomas Cihlar
    Molecular Pharmacology July 2008, 74 (1) 92-100; DOI: https://doi.org/10.1124/mol.108.045526
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    RNA Interference-Mediated Knockdown of Dynamin 2 Reduces Endocannabinoid Uptake into Neuronal dCAD Cells
    Matthew J. McFarland, Tamera K. Bardell, Marla L. Yates, Ekaterina A. Placzek and Eric L. Barker
    Molecular Pharmacology July 2008, 74 (1) 101-108; DOI: https://doi.org/10.1124/mol.108.044834
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    Histone Deacetylase Inhibitors Exert Time-Dependent Effects on Nuclear Factor-κB but Consistently Suppress the Expression of Proinflammatory Genes in Human Myometrial Cells
    Tamsin M. Lindström, Aarthi R. Mohan, Mark R. Johnson and Phillip R. Bennett
    Molecular Pharmacology July 2008, 74 (1) 109-121; DOI: https://doi.org/10.1124/mol.107.042838
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    Organic Anion Transporter 3 (Oat3/Slc22a8) Interacts with Carboxyfluoroquinolones, and Deletion Increases Systemic Exposure to Ciprofloxacin
    Adam L. VanWert, Chutima Srimaroeng and Douglas H. Sweet
    Molecular Pharmacology July 2008, 74 (1) 122-131; DOI: https://doi.org/10.1124/mol.107.042853
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    Roles of Accessory Subunits in α4β2* Nicotinic Receptors
    Alexandre Kuryatov, Jennifer Onksen and Jon Lindstrom
    Molecular Pharmacology July 2008, 74 (1) 132-143; DOI: https://doi.org/10.1124/mol.108.046789
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    Fluvastatin Synergistically Improves the Antiproliferative Effect of Everolimus on Rat Smooth Muscle Cells by Altering p27Kip1/Cyclin E Expression
    N. Ferri, A. Granata, C. Pirola, F. Torti, P. J. Pfister, R. Dorent and A. Corsini
    Molecular Pharmacology July 2008, 74 (1) 144-153; DOI: https://doi.org/10.1124/mol.108.046045
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    Molecular Mechanisms of Topical Anti-Inflammatory Effects of Lipoxin A4 in Endotoxin-Induced Uveitis
    Rodrigo Medeiros, Gustavo Büchele Rodrigues, Cláudia Pinto Figueiredo, Eduardo Büchele Rodrigues, Astor Grumman, Octavio Menezes-de-Lima, Giselle Fazzioni Passos and João Batista Calixto
    Molecular Pharmacology July 2008, 74 (1) 154-161; DOI: https://doi.org/10.1124/mol.108.046870
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    Conformational Rearrangements and Signaling Cascades Involved in Ligand-Biased Mitogen-Activated Protein Kinase Signaling through the β1-Adrenergic Receptor
    Ségolène Galandrin, Geneviève Oligny-Longpré, Hélène Bonin, Koji Ogawa, Céline Galés and Michel Bouvier
    Molecular Pharmacology July 2008, 74 (1) 162-172; DOI: https://doi.org/10.1124/mol.107.043893
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    AKT Is Activated in an Ataxia-Telangiectasia and Rad3-Related-Dependent Manner in Response to Temozolomide and Confers Protection against Drug-Induced Cell Growth Inhibition
    Simona Caporali, Lauretta Levati, Giuseppe Starace, Gianluca Ragone, Enzo Bonmassar, Ester Alvino and Stefania D'Atri
    Molecular Pharmacology July 2008, 74 (1) 173-183; DOI: https://doi.org/10.1124/mol.107.044743
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    Formaldehyde-Activated Pixantrone Is a Monofunctional DNA Alkylator That Binds Selectively to CpG and CpA Doublets
    Benny J. Evison, Francis Chiu, Gabriella Pezzoni, Don R. Phillips and Suzanne M. Cutts
    Molecular Pharmacology July 2008, 74 (1) 184-194; DOI: https://doi.org/10.1124/mol.108.045625
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    Arrestin Binds to Different Phosphorylated Regions of the Thyrotropin-Releasing Hormone Receptor with Distinct Functional Consequences
    Brian W. Jones and Patricia M. Hinkle
    Molecular Pharmacology July 2008, 74 (1) 195-202; DOI: https://doi.org/10.1124/mol.108.045948
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    Individually Monitoring Ligand-Induced Changes in the Structure of the GABAA Receptor at Benzodiazepine Binding Site and Non-Binding-Site Interfaces
    L. M. Sharkey and C. Czajkowski
    Molecular Pharmacology July 2008, 74 (1) 203-212; DOI: https://doi.org/10.1124/mol.108.044891
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    N-Palmitoyl Glycine, a Novel Endogenous Lipid That Acts As a Modulator of Calcium Influx and Nitric Oxide Production in Sensory Neurons
    Neta Rimmerman, Heather B. Bradshaw, H. Velocity Hughes, Jay Shih-Chieh Chen, Sherry Shu-Jung Hu, Douglas McHugh, Eivind Vefring, Jan A. Jahnsen, Eric L. Thompson, Kim Masuda, Benjamin F. Cravatt, Sumner Burstein, Michael R. Vasko, Anne L. Prieto, David K. O'Dell and J. Michael Walker
    Molecular Pharmacology July 2008, 74 (1) 213-224; DOI: https://doi.org/10.1124/mol.108.045997
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    Protection against Hydrogen Peroxide-Mediated Cytotoxicity in Friedreich's Ataxia Fibroblasts Using Novel Iron Chelators of the 2-Pyridylcarboxaldehyde Isonicotinoyl Hydrazone Class
    C. K. Lim, D. S. Kalinowski and D. R. Richardson
    Molecular Pharmacology July 2008, 74 (1) 225-235; DOI: https://doi.org/10.1124/mol.108.046847
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    Nitric Oxide Donor, (±)-S-Nitroso-N-acetylpenicillamine, Stabilizes Transactive Hypoxia-Inducible Factor-1α by Inhibiting von Hippel-Lindau Recruitment and Asparagine Hydroxylation
    Young-Kwon Park, Dae-Ro Ahn, Myoungsuk Oh, Taekyoung Lee, Eun Gyeong Yang, Miwon Son and Hyunsung Park
    Molecular Pharmacology July 2008, 74 (1) 236-245; DOI: https://doi.org/10.1124/mol.108.045278
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    Disruption of Signaling through SEK1 and MKK7 Yields Differential Responses in Hypoxic Colon Cancer Cells Treated with Oxaliplatin
    Irina A. Vasilevskaya, Muthu Selvakumaran and Peter J. O'Dwyer
    Molecular Pharmacology July 2008, 74 (1) 246-254; DOI: https://doi.org/10.1124/mol.107.044644
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    Roles of Cytosolic Phospholipase A2 and Src Kinase in the Early Action of 2,3,7,8-Tetrachlorodibenzo-p-dioxin through a Nongenomic Pathway in MCF10A Cells
    Bin Dong and Fumio Matsumura
    Molecular Pharmacology July 2008, 74 (1) 255-263; DOI: https://doi.org/10.1124/mol.107.044669
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    Characterization of mENT1Δ11, a Novel Alternative Splice Variant of the Mouse Equilibrative Nucleoside Transporter 1
    Kevin R. Robillard, Derek B.J. Bone, Jamie S. Park and James R. Hammond
    Molecular Pharmacology July 2008, 74 (1) 264-273; DOI: https://doi.org/10.1124/mol.107.041871
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    Inhibition of Nod2 Signaling and Target Gene Expression by Curcumin
    Shurong Huang, Ling Zhao, Kihoon Kim, Dong Seok Lee and Daniel H. Hwang
    Molecular Pharmacology July 2008, 74 (1) 274-281; DOI: https://doi.org/10.1124/mol.108.046169
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    (2R)-[(4-Biphenylylsulfonyl)amino]-N-hydroxy-3-phenylpropionamide (BiPS), a Matrix Metalloprotease Inhibitor, Is a Novel and Potent Activator of Hypoxia-Inducible Factors
    Marie-Claude Lauzier, Geneviève A. Robitaille, Denise A. Chan, Amato J. Giaccia and Darren E. Richard
    Molecular Pharmacology July 2008, 74 (1) 282-288; DOI: https://doi.org/10.1124/mol.108.045690
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    Selective Killing of Smad4-Negative Tumor Cells via a Designed Repressor Strategy
    Vidula Dixit and Rudy L. Juliano
    Molecular Pharmacology July 2008, 74 (1) 289-297; DOI: https://doi.org/10.1124/mol.108.046953
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    αvβ3 Integrin-Mediated Drug Resistance in Human Laryngeal Carcinoma Cells Is Caused by Glutathione-Dependent Elimination of Drug-Induced Reactive Oxidative Species
    Anamaria Brozović, Dragomira Majhen, Vibor Roje, Nevenka Mikac, Sanjica Jakopec, Gerhard Fritz, Maja Osmak and Andreja Ambriović-Ristov
    Molecular Pharmacology July 2008, 74 (1) 298-306; DOI: https://doi.org/10.1124/mol.107.043836

Erratum

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    Correction to Table of Contents (Volume 73, Number 6, June 2008)
    Molecular Pharmacology July 2008, 74 (1) 307; DOI: https://doi.org/10.1124/mol.74.1.307
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Molecular Pharmacology: 74 (1)
Molecular Pharmacology
Vol. 74, Issue 1
1 Jul 2008
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