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Molecular Pharmacology

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Table of Contents

August 01, 2008; Volume 74,Issue 2

Perspectives

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    Role of the Murine Organic Anion-Transporting Polypeptide 1b2 (Oatp1b2) in Drug Disposition and Hepatotoxicity
    Raymond Evers and Xiao-Yan Chu
    Molecular Pharmacology August 2008, 74 (2) 309-311; DOI: https://doi.org/10.1124/mol.108.048991
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    Rich Tapestry of G Protein-Coupled Receptor Signaling and Regulatory Mechanisms
    Vsevolod V. Gurevich and Eugenia V. Gurevich
    Molecular Pharmacology August 2008, 74 (2) 312-316; DOI: https://doi.org/10.1124/mol.108.049015
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    Protein-Protein Interactions and Dopamine D2 Receptor Signaling: A Calcium Connection
    Gregg D. Stanwood
    Molecular Pharmacology August 2008, 74 (2) 317-319; DOI: https://doi.org/10.1124/mol.108.049098

Accelerated Communications

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    Targeted Disruption of Murine Organic Anion-Transporting Polypeptide 1b2 (oatp1b2/Slco1b2) Significantly Alters Disposition of Prototypical Drug Substrates Pravastatin and Rifampin
    Hani Zaher, Henriette E. Meyer zu Schwabedissen, Rommel G. Tirona, Melissa L. Cox, Leslie A. Obert, Nidhi Agrawal, Joe Palandra, Jeffrey L. Stock, Richard B. Kim and Joseph A. Ware
    Molecular Pharmacology August 2008, 74 (2) 320-329; DOI: https://doi.org/10.1124/mol.108.046458
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    Simian Immunodeficiency Virus Is Susceptible to Inhibition by Carbohydrate-Binding Agents in a Manner Similar to That of HIV: Implications for Further Preclinical Drug Development
    Katrien O. François, Joeri Auwerx, Dominique Schols and Jan Balzarini
    Molecular Pharmacology August 2008, 74 (2) 330-337; DOI: https://doi.org/10.1124/mol.108.047621

Articles

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    M3 Muscarinic Acetylcholine Receptor-Mediated Signaling Is Regulated by Distinct Mechanisms
    Jiansong Luo, John M. Busillo and Jeffrey L. Benovic
    Molecular Pharmacology August 2008, 74 (2) 338-347; DOI: https://doi.org/10.1124/mol.107.044750
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    Presynaptic α7- and β2-Containing Nicotinic Acetylcholine Receptors Modulate Excitatory Amino Acid Release from Rat Prefrontal Cortex Nerve Terminals via Distinct Cellular Mechanisms
    Jane A. Dickinson, James N. C. Kew and Susan Wonnacott
    Molecular Pharmacology August 2008, 74 (2) 348-359; DOI: https://doi.org/10.1124/mol.108.046623
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    Postsynaptic Density-95 (PSD-95) and Calcineurin Control the Sensitivity of N-Methyl-d-aspartate Receptors to Calpain Cleavage in Cortical Neurons
    Eunice Y. Yuen, Yi Ren and Zhen Yan
    Molecular Pharmacology August 2008, 74 (2) 360-370; DOI: https://doi.org/10.1124/mol.108.046813
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    Novel Interaction of the Dopamine D2 Receptor and the Ca2+ Binding Protein S100B: Role in D2 Receptor Function
    Yong Liu, David C. Buck and Kim A. Neve
    Molecular Pharmacology August 2008, 74 (2) 371-378; DOI: https://doi.org/10.1124/mol.108.044925
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    Human Nocturnal Frontal Lobe Epilepsy: Pharmocogenomic Profiles of Pathogenic Nicotinic Acetylcholine Receptor β-Subunit Mutations outside the Ion Channel Pore
    Jean-Charles Hoda, Wenli Gu, Marc Friedli, Hilary A. Phillips, Sonia Bertrand, Stylianos E. Antonarakis, David Goudie, Richard Roberts, Ingrid E. Scheffer, Carla Marini, Jayesh Patel, Samuel F. Berkovic, John C. Mulley, Ortrud K. Steinlein and Daniel Bertrand
    Molecular Pharmacology August 2008, 74 (2) 379-391; DOI: https://doi.org/10.1124/mol.107.044545
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    Identification of Novel Formyl Peptide Receptor-Like 1 Agonists That Induce Macrophage Tumor Necrosis Factor α Production
    Igor A. Schepetkin, Liliya N. Kirpotina, Jun Tian, Andrei I. Khlebnikov, Richard D. Ye and Mark T. Quinn
    Molecular Pharmacology August 2008, 74 (2) 392-402; DOI: https://doi.org/10.1124/mol.108.046946
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    Adipose Fibroblast Growth Factor 21 Is Up-Regulated by Peroxisome Proliferator-Activated Receptor γ and Altered Metabolic States
    Eric S. Muise, Barbara Azzolina, David W. Kuo, Mohamed El-Sherbeini, Yejun Tan, Xiling Yuan, James Mu, John R. Thompson, Joel P. Berger and Kenny K. Wong
    Molecular Pharmacology August 2008, 74 (2) 403-412; DOI: https://doi.org/10.1124/mol.108.044826
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    Spatial Approximation between Secretin Residue Five and the Third Extracellular Loop of Its Receptor Provides New Insight into the Molecular Basis of Natural Agonist Binding
    Maoqing Dong, Polo C.-H. Lam, Delia I. Pinon, Patrick M. Sexton, Ruben Abagyan and Laurence J. Miller
    Molecular Pharmacology August 2008, 74 (2) 413-422; DOI: https://doi.org/10.1124/mol.108.047209
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    Enhancing Drug Accumulation in Saccharomyces cerevisiae by Repression of Pleiotropic Drug Resistance Genes with Chimeric Transcription Repressors
    Alexander Stepanov, Karin C. Nitiss, Geoffrey Neale and John L. Nitiss
    Molecular Pharmacology August 2008, 74 (2) 423-431; DOI: https://doi.org/10.1124/mol.107.044651
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    Protein Kinase C Enhances Tight Junction Barrier Function of Human Nasal Epithelial Cells in Primary Culture by Transcriptional Regulation
    Jun-ichi Koizumi, Takashi Kojima, Noriko Ogasawara, Ryuta Kamekura, Makoto Kurose, Mitsuru Go, Atsushi Harimaya, Masaki Murata, Makoto Osanai, Hideki Chiba, Tetsuo Himi and Norimasa Sawada
    Molecular Pharmacology August 2008, 74 (2) 432-442; DOI: https://doi.org/10.1124/mol.107.043711
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    The Peripheral Benzodiazepine Receptor Ligand 1-(2-Chlorophenyl-methylpropyl)-3-isoquinoline-carboxamide Is a Novel Antagonist of Human Constitutive Androstane Receptor
    Linhao Li, Tao Chen, Joseph D. Stanton, Tatsuya Sueyoshi, Masahiko Negishi and Hongbing Wang
    Molecular Pharmacology August 2008, 74 (2) 443-453; DOI: https://doi.org/10.1124/mol.108.046656
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    The NR1 M3 Domain Mediates Allosteric Coupling in the N-Methyl-D-aspartate Receptor
    Marie L. Blanke and Antonius M. J. VanDongen
    Molecular Pharmacology August 2008, 74 (2) 454-465; DOI: https://doi.org/10.1124/mol.107.044115
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    Morantel Allosterically Enhances Channel Gating of Neuronal Nicotinic Acetylcholine α3β2 Receptors
    Tse-Yu Wu, Caleb M. Smith, Steven M. Sine and Mark M. Levandoski
    Molecular Pharmacology August 2008, 74 (2) 466-475; DOI: https://doi.org/10.1124/mol.107.044388
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    Activation of Nuclear Factor-κB Pathway by Simvastatin and RhoA Silencing Increases Doxorubicin Cytotoxicity in Human Colon Cancer HT29 Cells
    Chiara Riganti, Sophie Doublier, Costanzo Costamagna, Elisabetta Aldieri, Gianpiero Pescarmona, Dario Ghigo and Amalia Bosia
    Molecular Pharmacology August 2008, 74 (2) 476-484; DOI: https://doi.org/10.1124/mol.108.045286
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    Synergy between Coproduced CC and CXC Chemokines in Monocyte Chemotaxis through Receptor-Mediated Events
    Mieke Gouwy, Sofie Struyf, Samuel Noppen, Evemie Schutyser, Jean-Yves Springael, Marc Parmentier, Paul Proost and Jo Van Damme
    Molecular Pharmacology August 2008, 74 (2) 485-495; DOI: https://doi.org/10.1124/mol.108.045146
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    T-Cell Receptor/CD28-Mediated Activation of Human T Lymphocytes Induces Expression of Functional μ-Opioid Receptors
    Christine Börner, Jürgen Kraus, Andrea Bedini, Burkhart Schraven and Volker Höllt
    Molecular Pharmacology August 2008, 74 (2) 496-504; DOI: https://doi.org/10.1124/mol.108.046029
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    Human Methyl Purine DNA Glycosylase and DNA Polymerase β Expression Collectively Predict Sensitivity to Temozolomide
    Ram N. Trivedi, Xiao-hong Wang, Elena Jelezcova, Eva M. Goellner, Jiang-bo Tang and Robert W. Sobol
    Molecular Pharmacology August 2008, 74 (2) 505-516; DOI: https://doi.org/10.1124/mol.108.045112
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    Transcriptional Repression of O6-Methylguanine DNA Methyltransferase Gene Rendering Cells Hypersensitive to N,N′-Bis(2-chloroethyl)-N-nitrosurea in Camptothecin-Resistant Cells
    Li-Chen Ma, Ching-Chuan Kuo, Jin-Fen Liu, Li-Tzong Chen and Jang-Yang Chang
    Molecular Pharmacology August 2008, 74 (2) 517-526; DOI: https://doi.org/10.1124/mol.107.043620
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    Cellular Energetic Status Supervises the Synthesis of Bis-Diphosphoinositol Tetrakisphosphate Independently of AMP-Activated Protein Kinase
    Kuicheon Choi, Elahe Mollapour, Jae H. Choi and Stephen B. Shears
    Molecular Pharmacology August 2008, 74 (2) 527-536; DOI: https://doi.org/10.1124/mol.107.044628

Errata

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    Correction to “Induction of Apoptosis by Vinblastine via c-Jun Autoamplification and p53-Independent Down-Regulation of p21WAF1/CIP1”
    Molecular Pharmacology August 2008, 74 (2) 537; DOI: https://doi.org/10.1124/mol.74.2.537
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    Correction to “A Functional Steroid-Binding Element in an ATP-Binding Cassette Multidrug Transporter”
    Molecular Pharmacology August 2008, 74 (2) 538; DOI: https://doi.org/10.1124/mol.74.2.538
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    Correction to “Stretch Induction of Cyclooxygenase-2 Expression in Human Urothelial Cells Is Calcium- and Protein Kinase Cζ-Dependent”
    Molecular Pharmacology August 2008, 74 (2) 539; DOI: https://doi.org/10.1124/mol.74.2.539
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    Correction to “Molecular Interaction of a Potent Nonpeptide Agonist with the Chemokine Receptor CCR8”
    Molecular Pharmacology August 2008, 74 (2) 539; DOI: https://doi.org/10.1124/mol.74.2.539-a
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In this issue

Molecular Pharmacology: 74 (2)
Molecular Pharmacology
Vol. 74, Issue 2
1 Aug 2008
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