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Index by author

October 01, 2008; Volume 74,Issue 4

A

  1. Aizenman, Elias

    1. Selective Inhibition of Mitogen-Activated Protein Kinase Phosphatases by Zinc Accounts for Extracellular Signal-Regulated Kinase 1/2-Dependent Oxidative Neuronal Cell Death
      Yeung Ho, Ranmal Samarasinghe, Megan E. Knoch, Marcia Lewis, Elias Aizenman and Donald B. DeFranco
      Molecular Pharmacology October 2008, 74 (4) 1141-1151; DOI: https://doi.org/10.1124/mol.108.049064

  2. Armbruster, Blaine N.

    1. New Insights into the Function of M4 Muscarinic Acetylcholine Receptors Gained Using a Novel Allosteric Modulator and a DREADD (Designer Receptor Exclusively Activated by a Designer Drug)
      Vindhya Nawaratne, Katie Leach, Nur Suratman, Richard E. Loiacono, Christian C. Felder, Blaine N. Armbruster, Bryan L. Roth, Patrick M. Sexton and Arthur Christopoulos
      Molecular Pharmacology October 2008, 74 (4) 1119-1131; DOI: https://doi.org/10.1124/mol.108.049353

  3. Arttamangkul, Seksiri

    1. Differential Activation and Trafficking of μ-Opioid Receptors in Brain Slices
      Seksiri Arttamangkul, Nidia Quillinan, Malcolm J. Low, Mark von Zastrow, John Pintar and John T. Williams
      Molecular Pharmacology October 2008, 74 (4) 972-979; DOI: https://doi.org/10.1124/mol.108.048512

B

  1. Bachmann, Malte

    1. Keratinocyte-Derived Vascular Endothelial Growth Factor Biosynthesis Represents a Pleiotropic Side Effect of Peroxisome Proliferator-Activated Receptor-γ Agonist Troglitazone but Not Rosiglitazone and Involves Activation of p38 Mitogen-Activated Protein Kinase: Implications for Diabetes-Impaired Skin Repair
      Dana Schiefelbein, Oliver Seitz, Itamar Goren, Jan Philipp Dißmann, Helmut Schmidt, Malte Bachmann, Robert Sader, Gerd Geisslinger, Josef Pfeilschifter and Stefan Frank
      Molecular Pharmacology October 2008, 74 (4) 952-963; DOI: https://doi.org/10.1124/mol.108.049395

  2. Bailey, Richard J.

    1. Identification of N-Terminal Receptor Activity-Modifying Protein Residues Important for Calcitonin Gene-Related Peptide, Adrenomedullin, and Amylin Receptor Function
      Tao Qi, George Christopoulos, Richard J. Bailey, Arthur Christopoulos, Patrick M. Sexton and Debbie L. Hay
      Molecular Pharmacology October 2008, 74 (4) 1059-1071; DOI: https://doi.org/10.1124/mol.108.047142

  3. Baldi, Alberto

    1. Histamine H2 Receptor Trafficking: Role of Arrestin, Dynamin, and Clathrin in Histamine H2 Receptor Internalization
      Natalia Fernandez, Federico Monczor, Alberto Baldi, Carlos Davio and Carina Shayo
      Molecular Pharmacology October 2008, 74 (4) 1109-1118; DOI: https://doi.org/10.1124/mol.108.045336

  4. Baumruker, Thomas

    1. Targeting Ceramide Metabolism with a Potent and Specific Ceramide Kinase Inhibitor
      Christine Graf, Martin Klumpp, Michael Habig, Philipp Rovina, Andreas Billich, Thomas Baumruker, Berndt Oberhauser and Frédéric Bornancin
      Molecular Pharmacology October 2008, 74 (4) 925-932; DOI: https://doi.org/10.1124/mol.108.048652

  5. Benned-Jensen, Tau

    1. Structural Motifs of Importance for the Constitutive Activity of the Orphan 7TM Receptor EBI2: Analysis of Receptor Activation in the Absence of an Agonist
      Tau Benned-Jensen and Mette M. Rosenkilde
      Molecular Pharmacology October 2008, 74 (4) 1008-1021; DOI: https://doi.org/10.1124/mol.108.049676

  6. Billich, Andreas

    1. Targeting Ceramide Metabolism with a Potent and Specific Ceramide Kinase Inhibitor
      Christine Graf, Martin Klumpp, Michael Habig, Philipp Rovina, Andreas Billich, Thomas Baumruker, Berndt Oberhauser and Frédéric Bornancin
      Molecular Pharmacology October 2008, 74 (4) 925-932; DOI: https://doi.org/10.1124/mol.108.048652

  7. Binda, Francesca

    1. Syntaxin 1A Interaction with the Dopamine Transporter Promotes Amphetamine-Induced Dopamine Efflux
      Francesca Binda, Concetta Dipace, Erica Bowton, Sabrina D. Robertson, Brandon J. Lute, Jacob U. Fog, Minjia Zhang, Namita Sen, Roger J. Colbran, Margaret E. Gnegy, Ulrik Gether, Jonathan A. Javitch, Kevin Erreger and Aurelio Galli
      Molecular Pharmacology October 2008, 74 (4) 1101-1108; DOI: https://doi.org/10.1124/mol.108.048447

  8. Bornancin, Frédéric

    1. Targeting Ceramide Metabolism with a Potent and Specific Ceramide Kinase Inhibitor
      Christine Graf, Martin Klumpp, Michael Habig, Philipp Rovina, Andreas Billich, Thomas Baumruker, Berndt Oberhauser and Frédéric Bornancin
      Molecular Pharmacology October 2008, 74 (4) 925-932; DOI: https://doi.org/10.1124/mol.108.048652

  9. Bowton, Erica

    1. Syntaxin 1A Interaction with the Dopamine Transporter Promotes Amphetamine-Induced Dopamine Efflux
      Francesca Binda, Concetta Dipace, Erica Bowton, Sabrina D. Robertson, Brandon J. Lute, Jacob U. Fog, Minjia Zhang, Namita Sen, Roger J. Colbran, Margaret E. Gnegy, Ulrik Gether, Jonathan A. Javitch, Kevin Erreger and Aurelio Galli
      Molecular Pharmacology October 2008, 74 (4) 1101-1108; DOI: https://doi.org/10.1124/mol.108.048447

  10. Braguer, D.

    1. Patupilone-Induced Apoptosis Is Mediated by Mitochondrial Reactive Oxygen Species through Bim Relocalization to Mitochondria
      N. R. Khawaja, M. Carré, H. Kovacic, M. A. Estève and D. Braguer
      Molecular Pharmacology October 2008, 74 (4) 1072-1083; DOI: https://doi.org/10.1124/mol.108.048405

  11. Brown, Colin D. A.

    1. Human Proximal Tubular Epithelium Actively Secretes but Does Not Retain Rosuvastatin
      Anja Verhulst, Rachel Sayer, Marc E. De Broe, Patrick C. D'Haese and Colin D. A. Brown
      Molecular Pharmacology October 2008, 74 (4) 1084-1091; DOI: https://doi.org/10.1124/mol.108.047647

  12. Bruhova, Iva

    1. Access and Binding of Local Anesthetics in the Closed Sodium Channel
      Iva Bruhova, Denis B. Tikhonov and Boris S. Zhorov
      Molecular Pharmacology October 2008, 74 (4) 1033-1045; DOI: https://doi.org/10.1124/mol.108.049759

  13. Bumpus, Namandjé N.

    1. Investigation of the Mechanisms Underlying the Differential Effects of the K262R Mutation of P450 2B6 on Catalytic Activity
      Namandjé N. Bumpus and Paul F. Hollenberg
      Molecular Pharmacology October 2008, 74 (4) 990-999; DOI: https://doi.org/10.1124/mol.108.048637

C

  1. Carré, M.

    1. Patupilone-Induced Apoptosis Is Mediated by Mitochondrial Reactive Oxygen Species through Bim Relocalization to Mitochondria
      N. R. Khawaja, M. Carré, H. Kovacic, M. A. Estève and D. Braguer
      Molecular Pharmacology October 2008, 74 (4) 1072-1083; DOI: https://doi.org/10.1124/mol.108.048405

  2. Chang, Wen-Liang

    1. The Induction of Orphan Nuclear Receptor Nur77 Expression by n-Butylenephthalide as Pharmaceuticals on Hepatocellular Carcinoma Cell Therapy
      Yi-Lin Chen, Min-Hui Jian, Chai-Ching Lin, Jung-Cheng Kang, Shee-Ping Chen, Po-Cheng Lin, Putzer-Joseph Hung, Jen-Ren Chen, Wen-Liang Chang, Shinn-Zong Lin and Horng-Jyh Harn
      Molecular Pharmacology October 2008, 74 (4) 1046-1058; DOI: https://doi.org/10.1124/mol.107.044800

  3. Chang, Yongchang

    1. Structural Determinants for Antagonist Pharmacology That Distinguish the ρ1 GABAC Receptor from GABAA Receptors
      Jianliang Zhang, Fenqin Xue and Yongchang Chang
      Molecular Pharmacology October 2008, 74 (4) 941-951; DOI: https://doi.org/10.1124/mol.108.048710

  4. Chen, Chunying

    1. Inhibition of Tumor Growth by Endohedral Metallofullerenol Nanoparticles Optimized as Reactive Oxygen Species Scavenger
      Jun-Jie Yin, Fang Lao, Jie Meng, Peter P. Fu, Yuliang Zhao, Gengmei Xing, Xueyun Gao, Baoyun Sun, Paul C. Wang, Chunying Chen and Xing-Jie Liang
      Molecular Pharmacology October 2008, 74 (4) 1132-1140; DOI: https://doi.org/10.1124/mol.108.048348

  5. Chen, Jen-Ren

    1. The Induction of Orphan Nuclear Receptor Nur77 Expression by n-Butylenephthalide as Pharmaceuticals on Hepatocellular Carcinoma Cell Therapy
      Yi-Lin Chen, Min-Hui Jian, Chai-Ching Lin, Jung-Cheng Kang, Shee-Ping Chen, Po-Cheng Lin, Putzer-Joseph Hung, Jen-Ren Chen, Wen-Liang Chang, Shinn-Zong Lin and Horng-Jyh Harn
      Molecular Pharmacology October 2008, 74 (4) 1046-1058; DOI: https://doi.org/10.1124/mol.107.044800

  6. Chen, Shee-Ping

    1. The Induction of Orphan Nuclear Receptor Nur77 Expression by n-Butylenephthalide as Pharmaceuticals on Hepatocellular Carcinoma Cell Therapy
      Yi-Lin Chen, Min-Hui Jian, Chai-Ching Lin, Jung-Cheng Kang, Shee-Ping Chen, Po-Cheng Lin, Putzer-Joseph Hung, Jen-Ren Chen, Wen-Liang Chang, Shinn-Zong Lin and Horng-Jyh Harn
      Molecular Pharmacology October 2008, 74 (4) 1046-1058; DOI: https://doi.org/10.1124/mol.107.044800

  7. Chen, Yi-Lin

    1. The Induction of Orphan Nuclear Receptor Nur77 Expression by n-Butylenephthalide as Pharmaceuticals on Hepatocellular Carcinoma Cell Therapy
      Yi-Lin Chen, Min-Hui Jian, Chai-Ching Lin, Jung-Cheng Kang, Shee-Ping Chen, Po-Cheng Lin, Putzer-Joseph Hung, Jen-Ren Chen, Wen-Liang Chang, Shinn-Zong Lin and Horng-Jyh Harn
      Molecular Pharmacology October 2008, 74 (4) 1046-1058; DOI: https://doi.org/10.1124/mol.107.044800

  8. Christopoulos, Arthur

    1. Identification of N-Terminal Receptor Activity-Modifying Protein Residues Important for Calcitonin Gene-Related Peptide, Adrenomedullin, and Amylin Receptor Function
      Tao Qi, George Christopoulos, Richard J. Bailey, Arthur Christopoulos, Patrick M. Sexton and Debbie L. Hay
      Molecular Pharmacology October 2008, 74 (4) 1059-1071; DOI: https://doi.org/10.1124/mol.108.047142
    2. New Insights into the Function of M4 Muscarinic Acetylcholine Receptors Gained Using a Novel Allosteric Modulator and a DREADD (Designer Receptor Exclusively Activated by a Designer Drug)
      Vindhya Nawaratne, Katie Leach, Nur Suratman, Richard E. Loiacono, Christian C. Felder, Blaine N. Armbruster, Bryan L. Roth, Patrick M. Sexton and Arthur Christopoulos
      Molecular Pharmacology October 2008, 74 (4) 1119-1131; DOI: https://doi.org/10.1124/mol.108.049353

  9. Christopoulos, George

    1. Identification of N-Terminal Receptor Activity-Modifying Protein Residues Important for Calcitonin Gene-Related Peptide, Adrenomedullin, and Amylin Receptor Function
      Tao Qi, George Christopoulos, Richard J. Bailey, Arthur Christopoulos, Patrick M. Sexton and Debbie L. Hay
      Molecular Pharmacology October 2008, 74 (4) 1059-1071; DOI: https://doi.org/10.1124/mol.108.047142

  10. Clair, Daret K. St.

    1. The α1D-Adrenergic Receptor Induces Vascular Smooth Muscle Apoptosis via a p53-Dependent Mechanism
      Mary L. García-Cazarín, Jennifer L. Smith, Daret K. St. Clair and Michael T. Piascik
      Molecular Pharmacology October 2008, 74 (4) 1000-1007; DOI: https://doi.org/10.1124/mol.108.047993

  11. Clarke, Christopher J.

    1. Regulation of Neutral Sphingomyelinase-2 (nSMase2) by Tumor Necrosis Factor-α Involves Protein Kinase C-δ in Lung Epithelial Cells
      Christopher J. Clarke, J. Michael Guthrie and Yusuf A. Hannun
      Molecular Pharmacology October 2008, 74 (4) 1022-1032; DOI: https://doi.org/10.1124/mol.108.046250

  12. Colbran, Roger J.

    1. Syntaxin 1A Interaction with the Dopamine Transporter Promotes Amphetamine-Induced Dopamine Efflux
      Francesca Binda, Concetta Dipace, Erica Bowton, Sabrina D. Robertson, Brandon J. Lute, Jacob U. Fog, Minjia Zhang, Namita Sen, Roger J. Colbran, Margaret E. Gnegy, Ulrik Gether, Jonathan A. Javitch, Kevin Erreger and Aurelio Galli
      Molecular Pharmacology October 2008, 74 (4) 1101-1108; DOI: https://doi.org/10.1124/mol.108.048447

D

  1. D'Haese, Patrick C.

    1. Human Proximal Tubular Epithelium Actively Secretes but Does Not Retain Rosuvastatin
      Anja Verhulst, Rachel Sayer, Marc E. De Broe, Patrick C. D'Haese and Colin D. A. Brown
      Molecular Pharmacology October 2008, 74 (4) 1084-1091; DOI: https://doi.org/10.1124/mol.108.047647

  2. Daignan-Fornier, Bertrand

    1. Dysregulation of Purine Nucleotide Biosynthesis Pathways Modulates Cisplatin Cytotoxicity in Saccharomyces cerevisiae
      David Kowalski, Lakshmi Pendyala, Bertrand Daignan-Fornier, Stephen B. Howell and Ruea-Yea Huang
      Molecular Pharmacology October 2008, 74 (4) 1092-1100; DOI: https://doi.org/10.1124/mol.108.048256

  3. Davio, Carlos

    1. Histamine H2 Receptor Trafficking: Role of Arrestin, Dynamin, and Clathrin in Histamine H2 Receptor Internalization
      Natalia Fernandez, Federico Monczor, Alberto Baldi, Carlos Davio and Carina Shayo
      Molecular Pharmacology October 2008, 74 (4) 1109-1118; DOI: https://doi.org/10.1124/mol.108.045336

  4. De Broe, Marc E.

    1. Human Proximal Tubular Epithelium Actively Secretes but Does Not Retain Rosuvastatin
      Anja Verhulst, Rachel Sayer, Marc E. De Broe, Patrick C. D'Haese and Colin D. A. Brown
      Molecular Pharmacology October 2008, 74 (4) 1084-1091; DOI: https://doi.org/10.1124/mol.108.047647

  5. DeFranco, Donald B.

    1. Selective Inhibition of Mitogen-Activated Protein Kinase Phosphatases by Zinc Accounts for Extracellular Signal-Regulated Kinase 1/2-Dependent Oxidative Neuronal Cell Death
      Yeung Ho, Ranmal Samarasinghe, Megan E. Knoch, Marcia Lewis, Elias Aizenman and Donald B. DeFranco
      Molecular Pharmacology October 2008, 74 (4) 1141-1151; DOI: https://doi.org/10.1124/mol.108.049064

  6. Dipace, Concetta

    1. Syntaxin 1A Interaction with the Dopamine Transporter Promotes Amphetamine-Induced Dopamine Efflux
      Francesca Binda, Concetta Dipace, Erica Bowton, Sabrina D. Robertson, Brandon J. Lute, Jacob U. Fog, Minjia Zhang, Namita Sen, Roger J. Colbran, Margaret E. Gnegy, Ulrik Gether, Jonathan A. Javitch, Kevin Erreger and Aurelio Galli
      Molecular Pharmacology October 2008, 74 (4) 1101-1108; DOI: https://doi.org/10.1124/mol.108.048447

  7. Dißmann, Jan Philipp

    1. Keratinocyte-Derived Vascular Endothelial Growth Factor Biosynthesis Represents a Pleiotropic Side Effect of Peroxisome Proliferator-Activated Receptor-γ Agonist Troglitazone but Not Rosiglitazone and Involves Activation of p38 Mitogen-Activated Protein Kinase: Implications for Diabetes-Impaired Skin Repair
      Dana Schiefelbein, Oliver Seitz, Itamar Goren, Jan Philipp Dißmann, Helmut Schmidt, Malte Bachmann, Robert Sader, Gerd Geisslinger, Josef Pfeilschifter and Stefan Frank
      Molecular Pharmacology October 2008, 74 (4) 952-963; DOI: https://doi.org/10.1124/mol.108.049395

E

  1. El-Sheikh, Azza A. K.

    1. Functional Role of Arginine 375 in Transmembrane Helix 6 of Multidrug Resistance Protein 4 (MRP4/ABCC4)
      Azza A. K. El-Sheikh, Jeroen J. M. W. van den Heuvel, Elmar Krieger, Frans G. M. Russel and Jan B. Koenderink
      Molecular Pharmacology October 2008, 74 (4) 964-971; DOI: https://doi.org/10.1124/mol.107.043661

  2. Erreger, Kevin

    1. Syntaxin 1A Interaction with the Dopamine Transporter Promotes Amphetamine-Induced Dopamine Efflux
      Francesca Binda, Concetta Dipace, Erica Bowton, Sabrina D. Robertson, Brandon J. Lute, Jacob U. Fog, Minjia Zhang, Namita Sen, Roger J. Colbran, Margaret E. Gnegy, Ulrik Gether, Jonathan A. Javitch, Kevin Erreger and Aurelio Galli
      Molecular Pharmacology October 2008, 74 (4) 1101-1108; DOI: https://doi.org/10.1124/mol.108.048447

  3. Estève, M. A.

    1. Patupilone-Induced Apoptosis Is Mediated by Mitochondrial Reactive Oxygen Species through Bim Relocalization to Mitochondria
      N. R. Khawaja, M. Carré, H. Kovacic, M. A. Estève and D. Braguer
      Molecular Pharmacology October 2008, 74 (4) 1072-1083; DOI: https://doi.org/10.1124/mol.108.048405

F

  1. Felder, Christian C.

    1. New Insights into the Function of M4 Muscarinic Acetylcholine Receptors Gained Using a Novel Allosteric Modulator and a DREADD (Designer Receptor Exclusively Activated by a Designer Drug)
      Vindhya Nawaratne, Katie Leach, Nur Suratman, Richard E. Loiacono, Christian C. Felder, Blaine N. Armbruster, Bryan L. Roth, Patrick M. Sexton and Arthur Christopoulos
      Molecular Pharmacology October 2008, 74 (4) 1119-1131; DOI: https://doi.org/10.1124/mol.108.049353

  2. Fernandez, Natalia

    1. Histamine H2 Receptor Trafficking: Role of Arrestin, Dynamin, and Clathrin in Histamine H2 Receptor Internalization
      Natalia Fernandez, Federico Monczor, Alberto Baldi, Carlos Davio and Carina Shayo
      Molecular Pharmacology October 2008, 74 (4) 1109-1118; DOI: https://doi.org/10.1124/mol.108.045336

  3. Fog, Jacob U.

    1. Syntaxin 1A Interaction with the Dopamine Transporter Promotes Amphetamine-Induced Dopamine Efflux
      Francesca Binda, Concetta Dipace, Erica Bowton, Sabrina D. Robertson, Brandon J. Lute, Jacob U. Fog, Minjia Zhang, Namita Sen, Roger J. Colbran, Margaret E. Gnegy, Ulrik Gether, Jonathan A. Javitch, Kevin Erreger and Aurelio Galli
      Molecular Pharmacology October 2008, 74 (4) 1101-1108; DOI: https://doi.org/10.1124/mol.108.048447

  4. Frank, Stefan

    1. Keratinocyte-Derived Vascular Endothelial Growth Factor Biosynthesis Represents a Pleiotropic Side Effect of Peroxisome Proliferator-Activated Receptor-γ Agonist Troglitazone but Not Rosiglitazone and Involves Activation of p38 Mitogen-Activated Protein Kinase: Implications for Diabetes-Impaired Skin Repair
      Dana Schiefelbein, Oliver Seitz, Itamar Goren, Jan Philipp Dißmann, Helmut Schmidt, Malte Bachmann, Robert Sader, Gerd Geisslinger, Josef Pfeilschifter and Stefan Frank
      Molecular Pharmacology October 2008, 74 (4) 952-963; DOI: https://doi.org/10.1124/mol.108.049395

  5. Fu, Peter P.

    1. Inhibition of Tumor Growth by Endohedral Metallofullerenol Nanoparticles Optimized as Reactive Oxygen Species Scavenger
      Jun-Jie Yin, Fang Lao, Jie Meng, Peter P. Fu, Yuliang Zhao, Gengmei Xing, Xueyun Gao, Baoyun Sun, Paul C. Wang, Chunying Chen and Xing-Jie Liang
      Molecular Pharmacology October 2008, 74 (4) 1132-1140; DOI: https://doi.org/10.1124/mol.108.048348

G

  1. Galetin, Aleksandra

    1. Kinetic Modeling of the Interactions between 4-Methylumbelliferone, 1-Naphthol, and Zidovudine Glucuronidation by UDP-Glucuronosyltransferase 2B7 (UGT2B7) Provides Evidence for Multiple Substrate Binding and Effector Sites
      Verawan Uchaipichat, Aleksandra Galetin, J. Brian Houston, Peter I. Mackenzie, J. Andrew Williams and John O. Miners
      Molecular Pharmacology October 2008, 74 (4) 1152-1162; DOI: https://doi.org/10.1124/mol.108.048645

  2. Galli, Aurelio

    1. Syntaxin 1A Interaction with the Dopamine Transporter Promotes Amphetamine-Induced Dopamine Efflux
      Francesca Binda, Concetta Dipace, Erica Bowton, Sabrina D. Robertson, Brandon J. Lute, Jacob U. Fog, Minjia Zhang, Namita Sen, Roger J. Colbran, Margaret E. Gnegy, Ulrik Gether, Jonathan A. Javitch, Kevin Erreger and Aurelio Galli
      Molecular Pharmacology October 2008, 74 (4) 1101-1108; DOI: https://doi.org/10.1124/mol.108.048447

  3. Gao, Xueyun

    1. Inhibition of Tumor Growth by Endohedral Metallofullerenol Nanoparticles Optimized as Reactive Oxygen Species Scavenger
      Jun-Jie Yin, Fang Lao, Jie Meng, Peter P. Fu, Yuliang Zhao, Gengmei Xing, Xueyun Gao, Baoyun Sun, Paul C. Wang, Chunying Chen and Xing-Jie Liang
      Molecular Pharmacology October 2008, 74 (4) 1132-1140; DOI: https://doi.org/10.1124/mol.108.048348

  4. García-Cazarín, Mary L.

    1. The α1D-Adrenergic Receptor Induces Vascular Smooth Muscle Apoptosis via a p53-Dependent Mechanism
      Mary L. García-Cazarín, Jennifer L. Smith, Daret K. St. Clair and Michael T. Piascik
      Molecular Pharmacology October 2008, 74 (4) 1000-1007; DOI: https://doi.org/10.1124/mol.108.047993

  5. Geisslinger, Gerd

    1. Keratinocyte-Derived Vascular Endothelial Growth Factor Biosynthesis Represents a Pleiotropic Side Effect of Peroxisome Proliferator-Activated Receptor-γ Agonist Troglitazone but Not Rosiglitazone and Involves Activation of p38 Mitogen-Activated Protein Kinase: Implications for Diabetes-Impaired Skin Repair
      Dana Schiefelbein, Oliver Seitz, Itamar Goren, Jan Philipp Dißmann, Helmut Schmidt, Malte Bachmann, Robert Sader, Gerd Geisslinger, Josef Pfeilschifter and Stefan Frank
      Molecular Pharmacology October 2008, 74 (4) 952-963; DOI: https://doi.org/10.1124/mol.108.049395

  6. Gether, Ulrik

    1. Syntaxin 1A Interaction with the Dopamine Transporter Promotes Amphetamine-Induced Dopamine Efflux
      Francesca Binda, Concetta Dipace, Erica Bowton, Sabrina D. Robertson, Brandon J. Lute, Jacob U. Fog, Minjia Zhang, Namita Sen, Roger J. Colbran, Margaret E. Gnegy, Ulrik Gether, Jonathan A. Javitch, Kevin Erreger and Aurelio Galli
      Molecular Pharmacology October 2008, 74 (4) 1101-1108; DOI: https://doi.org/10.1124/mol.108.048447

  7. Gnegy, Margaret E.

    1. Syntaxin 1A Interaction with the Dopamine Transporter Promotes Amphetamine-Induced Dopamine Efflux
      Francesca Binda, Concetta Dipace, Erica Bowton, Sabrina D. Robertson, Brandon J. Lute, Jacob U. Fog, Minjia Zhang, Namita Sen, Roger J. Colbran, Margaret E. Gnegy, Ulrik Gether, Jonathan A. Javitch, Kevin Erreger and Aurelio Galli
      Molecular Pharmacology October 2008, 74 (4) 1101-1108; DOI: https://doi.org/10.1124/mol.108.048447

  8. Goren, Itamar

    1. Keratinocyte-Derived Vascular Endothelial Growth Factor Biosynthesis Represents a Pleiotropic Side Effect of Peroxisome Proliferator-Activated Receptor-γ Agonist Troglitazone but Not Rosiglitazone and Involves Activation of p38 Mitogen-Activated Protein Kinase: Implications for Diabetes-Impaired Skin Repair
      Dana Schiefelbein, Oliver Seitz, Itamar Goren, Jan Philipp Dißmann, Helmut Schmidt, Malte Bachmann, Robert Sader, Gerd Geisslinger, Josef Pfeilschifter and Stefan Frank
      Molecular Pharmacology October 2008, 74 (4) 952-963; DOI: https://doi.org/10.1124/mol.108.049395

  9. Graf, Christine

    1. Targeting Ceramide Metabolism with a Potent and Specific Ceramide Kinase Inhibitor
      Christine Graf, Martin Klumpp, Michael Habig, Philipp Rovina, Andreas Billich, Thomas Baumruker, Berndt Oberhauser and Frédéric Bornancin
      Molecular Pharmacology October 2008, 74 (4) 925-932; DOI: https://doi.org/10.1124/mol.108.048652

  10. Green, Tim

    1. Mutations to the Kainate Receptor Subunit GluR6 Binding Pocket That Selectively Affect Domoate Binding
      Yihong Zhang, Naushaba Nayeem and Tim Green
      Molecular Pharmacology October 2008, 74 (4) 1163-1169; DOI: https://doi.org/10.1124/mol.108.048819

  11. Guerreiro, Serge

    1. Paraxanthine, the Primary Metabolite of Caffeine, Provides Protection against Dopaminergic Cell Death via Stimulation of Ryanodine Receptor Channels
      Serge Guerreiro, Damien Toulorge, Etienne Hirsch, Marc Marien, Pierre Sokoloff and Patrick P. Michel
      Molecular Pharmacology October 2008, 74 (4) 980-989; DOI: https://doi.org/10.1124/mol.108.048207

  12. Guthrie, J. Michael

    1. Regulation of Neutral Sphingomyelinase-2 (nSMase2) by Tumor Necrosis Factor-α Involves Protein Kinase C-δ in Lung Epithelial Cells
      Christopher J. Clarke, J. Michael Guthrie and Yusuf A. Hannun
      Molecular Pharmacology October 2008, 74 (4) 1022-1032; DOI: https://doi.org/10.1124/mol.108.046250

H

  1. Habig, Michael

    1. Targeting Ceramide Metabolism with a Potent and Specific Ceramide Kinase Inhibitor
      Christine Graf, Martin Klumpp, Michael Habig, Philipp Rovina, Andreas Billich, Thomas Baumruker, Berndt Oberhauser and Frédéric Bornancin
      Molecular Pharmacology October 2008, 74 (4) 925-932; DOI: https://doi.org/10.1124/mol.108.048652

  2. Hannun, Yusuf A.

    1. Regulation of Neutral Sphingomyelinase-2 (nSMase2) by Tumor Necrosis Factor-α Involves Protein Kinase C-δ in Lung Epithelial Cells
      Christopher J. Clarke, J. Michael Guthrie and Yusuf A. Hannun
      Molecular Pharmacology October 2008, 74 (4) 1022-1032; DOI: https://doi.org/10.1124/mol.108.046250

  3. Harn, Horng-Jyh

    1. The Induction of Orphan Nuclear Receptor Nur77 Expression by n-Butylenephthalide as Pharmaceuticals on Hepatocellular Carcinoma Cell Therapy
      Yi-Lin Chen, Min-Hui Jian, Chai-Ching Lin, Jung-Cheng Kang, Shee-Ping Chen, Po-Cheng Lin, Putzer-Joseph Hung, Jen-Ren Chen, Wen-Liang Chang, Shinn-Zong Lin and Horng-Jyh Harn
      Molecular Pharmacology October 2008, 74 (4) 1046-1058; DOI: https://doi.org/10.1124/mol.107.044800

  4. Hay, Debbie L.

    1. Identification of N-Terminal Receptor Activity-Modifying Protein Residues Important for Calcitonin Gene-Related Peptide, Adrenomedullin, and Amylin Receptor Function
      Tao Qi, George Christopoulos, Richard J. Bailey, Arthur Christopoulos, Patrick M. Sexton and Debbie L. Hay
      Molecular Pharmacology October 2008, 74 (4) 1059-1071; DOI: https://doi.org/10.1124/mol.108.047142

  5. Hirsch, Etienne

    1. Paraxanthine, the Primary Metabolite of Caffeine, Provides Protection against Dopaminergic Cell Death via Stimulation of Ryanodine Receptor Channels
      Serge Guerreiro, Damien Toulorge, Etienne Hirsch, Marc Marien, Pierre Sokoloff and Patrick P. Michel
      Molecular Pharmacology October 2008, 74 (4) 980-989; DOI: https://doi.org/10.1124/mol.108.048207

  6. Ho, Yeung

    1. Selective Inhibition of Mitogen-Activated Protein Kinase Phosphatases by Zinc Accounts for Extracellular Signal-Regulated Kinase 1/2-Dependent Oxidative Neuronal Cell Death
      Yeung Ho, Ranmal Samarasinghe, Megan E. Knoch, Marcia Lewis, Elias Aizenman and Donald B. DeFranco
      Molecular Pharmacology October 2008, 74 (4) 1141-1151; DOI: https://doi.org/10.1124/mol.108.049064

  7. Hollenberg, Paul F.

    1. Investigation of the Mechanisms Underlying the Differential Effects of the K262R Mutation of P450 2B6 on Catalytic Activity
      Namandjé N. Bumpus and Paul F. Hollenberg
      Molecular Pharmacology October 2008, 74 (4) 990-999; DOI: https://doi.org/10.1124/mol.108.048637

  8. Houston, J. Brian

    1. Kinetic Modeling of the Interactions between 4-Methylumbelliferone, 1-Naphthol, and Zidovudine Glucuronidation by UDP-Glucuronosyltransferase 2B7 (UGT2B7) Provides Evidence for Multiple Substrate Binding and Effector Sites
      Verawan Uchaipichat, Aleksandra Galetin, J. Brian Houston, Peter I. Mackenzie, J. Andrew Williams and John O. Miners
      Molecular Pharmacology October 2008, 74 (4) 1152-1162; DOI: https://doi.org/10.1124/mol.108.048645

  9. Howell, Stephen B.

    1. Dysregulation of Purine Nucleotide Biosynthesis Pathways Modulates Cisplatin Cytotoxicity in Saccharomyces cerevisiae
      David Kowalski, Lakshmi Pendyala, Bertrand Daignan-Fornier, Stephen B. Howell and Ruea-Yea Huang
      Molecular Pharmacology October 2008, 74 (4) 1092-1100; DOI: https://doi.org/10.1124/mol.108.048256

  10. Huang, Ruea-Yea

    1. Dysregulation of Purine Nucleotide Biosynthesis Pathways Modulates Cisplatin Cytotoxicity in Saccharomyces cerevisiae
      David Kowalski, Lakshmi Pendyala, Bertrand Daignan-Fornier, Stephen B. Howell and Ruea-Yea Huang
      Molecular Pharmacology October 2008, 74 (4) 1092-1100; DOI: https://doi.org/10.1124/mol.108.048256

  11. Hung, Putzer-Joseph

    1. The Induction of Orphan Nuclear Receptor Nur77 Expression by n-Butylenephthalide as Pharmaceuticals on Hepatocellular Carcinoma Cell Therapy
      Yi-Lin Chen, Min-Hui Jian, Chai-Ching Lin, Jung-Cheng Kang, Shee-Ping Chen, Po-Cheng Lin, Putzer-Joseph Hung, Jen-Ren Chen, Wen-Liang Chang, Shinn-Zong Lin and Horng-Jyh Harn
      Molecular Pharmacology October 2008, 74 (4) 1046-1058; DOI: https://doi.org/10.1124/mol.107.044800

J

  1. Javitch, Jonathan A.

    1. Syntaxin 1A Interaction with the Dopamine Transporter Promotes Amphetamine-Induced Dopamine Efflux
      Francesca Binda, Concetta Dipace, Erica Bowton, Sabrina D. Robertson, Brandon J. Lute, Jacob U. Fog, Minjia Zhang, Namita Sen, Roger J. Colbran, Margaret E. Gnegy, Ulrik Gether, Jonathan A. Javitch, Kevin Erreger and Aurelio Galli
      Molecular Pharmacology October 2008, 74 (4) 1101-1108; DOI: https://doi.org/10.1124/mol.108.048447

  2. Jian, Min-Hui

    1. The Induction of Orphan Nuclear Receptor Nur77 Expression by n-Butylenephthalide as Pharmaceuticals on Hepatocellular Carcinoma Cell Therapy
      Yi-Lin Chen, Min-Hui Jian, Chai-Ching Lin, Jung-Cheng Kang, Shee-Ping Chen, Po-Cheng Lin, Putzer-Joseph Hung, Jen-Ren Chen, Wen-Liang Chang, Shinn-Zong Lin and Horng-Jyh Harn
      Molecular Pharmacology October 2008, 74 (4) 1046-1058; DOI: https://doi.org/10.1124/mol.107.044800

K

  1. Kang, Jung-Cheng

    1. The Induction of Orphan Nuclear Receptor Nur77 Expression by n-Butylenephthalide as Pharmaceuticals on Hepatocellular Carcinoma Cell Therapy
      Yi-Lin Chen, Min-Hui Jian, Chai-Ching Lin, Jung-Cheng Kang, Shee-Ping Chen, Po-Cheng Lin, Putzer-Joseph Hung, Jen-Ren Chen, Wen-Liang Chang, Shinn-Zong Lin and Horng-Jyh Harn
      Molecular Pharmacology October 2008, 74 (4) 1046-1058; DOI: https://doi.org/10.1124/mol.107.044800

  2. Khawaja, N. R.

    1. Patupilone-Induced Apoptosis Is Mediated by Mitochondrial Reactive Oxygen Species through Bim Relocalization to Mitochondria
      N. R. Khawaja, M. Carré, H. Kovacic, M. A. Estève and D. Braguer
      Molecular Pharmacology October 2008, 74 (4) 1072-1083; DOI: https://doi.org/10.1124/mol.108.048405

  3. Klumpp, Martin

    1. Targeting Ceramide Metabolism with a Potent and Specific Ceramide Kinase Inhibitor
      Christine Graf, Martin Klumpp, Michael Habig, Philipp Rovina, Andreas Billich, Thomas Baumruker, Berndt Oberhauser and Frédéric Bornancin
      Molecular Pharmacology October 2008, 74 (4) 925-932; DOI: https://doi.org/10.1124/mol.108.048652

  4. Knoch, Megan E.

    1. Selective Inhibition of Mitogen-Activated Protein Kinase Phosphatases by Zinc Accounts for Extracellular Signal-Regulated Kinase 1/2-Dependent Oxidative Neuronal Cell Death
      Yeung Ho, Ranmal Samarasinghe, Megan E. Knoch, Marcia Lewis, Elias Aizenman and Donald B. DeFranco
      Molecular Pharmacology October 2008, 74 (4) 1141-1151; DOI: https://doi.org/10.1124/mol.108.049064

  5. Koenderink, Jan B.

    1. Functional Role of Arginine 375 in Transmembrane Helix 6 of Multidrug Resistance Protein 4 (MRP4/ABCC4)
      Azza A. K. El-Sheikh, Jeroen J. M. W. van den Heuvel, Elmar Krieger, Frans G. M. Russel and Jan B. Koenderink
      Molecular Pharmacology October 2008, 74 (4) 964-971; DOI: https://doi.org/10.1124/mol.107.043661

  6. Kovacic, H.

    1. Patupilone-Induced Apoptosis Is Mediated by Mitochondrial Reactive Oxygen Species through Bim Relocalization to Mitochondria
      N. R. Khawaja, M. Carré, H. Kovacic, M. A. Estève and D. Braguer
      Molecular Pharmacology October 2008, 74 (4) 1072-1083; DOI: https://doi.org/10.1124/mol.108.048405

  7. Kowalski, David

    1. Dysregulation of Purine Nucleotide Biosynthesis Pathways Modulates Cisplatin Cytotoxicity in Saccharomyces cerevisiae
      David Kowalski, Lakshmi Pendyala, Bertrand Daignan-Fornier, Stephen B. Howell and Ruea-Yea Huang
      Molecular Pharmacology October 2008, 74 (4) 1092-1100; DOI: https://doi.org/10.1124/mol.108.048256

  8. Krieger, Elmar

    1. Functional Role of Arginine 375 in Transmembrane Helix 6 of Multidrug Resistance Protein 4 (MRP4/ABCC4)
      Azza A. K. El-Sheikh, Jeroen J. M. W. van den Heuvel, Elmar Krieger, Frans G. M. Russel and Jan B. Koenderink
      Molecular Pharmacology October 2008, 74 (4) 964-971; DOI: https://doi.org/10.1124/mol.107.043661

L

  1. Lao, Fang

    1. Inhibition of Tumor Growth by Endohedral Metallofullerenol Nanoparticles Optimized as Reactive Oxygen Species Scavenger
      Jun-Jie Yin, Fang Lao, Jie Meng, Peter P. Fu, Yuliang Zhao, Gengmei Xing, Xueyun Gao, Baoyun Sun, Paul C. Wang, Chunying Chen and Xing-Jie Liang
      Molecular Pharmacology October 2008, 74 (4) 1132-1140; DOI: https://doi.org/10.1124/mol.108.048348

  2. Leach, Katie

    1. New Insights into the Function of M4 Muscarinic Acetylcholine Receptors Gained Using a Novel Allosteric Modulator and a DREADD (Designer Receptor Exclusively Activated by a Designer Drug)
      Vindhya Nawaratne, Katie Leach, Nur Suratman, Richard E. Loiacono, Christian C. Felder, Blaine N. Armbruster, Bryan L. Roth, Patrick M. Sexton and Arthur Christopoulos
      Molecular Pharmacology October 2008, 74 (4) 1119-1131; DOI: https://doi.org/10.1124/mol.108.049353

  3. Lewis, Marcia

    1. Selective Inhibition of Mitogen-Activated Protein Kinase Phosphatases by Zinc Accounts for Extracellular Signal-Regulated Kinase 1/2-Dependent Oxidative Neuronal Cell Death
      Yeung Ho, Ranmal Samarasinghe, Megan E. Knoch, Marcia Lewis, Elias Aizenman and Donald B. DeFranco
      Molecular Pharmacology October 2008, 74 (4) 1141-1151; DOI: https://doi.org/10.1124/mol.108.049064

  4. Liang, Xing-Jie

    1. Inhibition of Tumor Growth by Endohedral Metallofullerenol Nanoparticles Optimized as Reactive Oxygen Species Scavenger
      Jun-Jie Yin, Fang Lao, Jie Meng, Peter P. Fu, Yuliang Zhao, Gengmei Xing, Xueyun Gao, Baoyun Sun, Paul C. Wang, Chunying Chen and Xing-Jie Liang
      Molecular Pharmacology October 2008, 74 (4) 1132-1140; DOI: https://doi.org/10.1124/mol.108.048348

  5. Lin, Chai-Ching

    1. The Induction of Orphan Nuclear Receptor Nur77 Expression by n-Butylenephthalide as Pharmaceuticals on Hepatocellular Carcinoma Cell Therapy
      Yi-Lin Chen, Min-Hui Jian, Chai-Ching Lin, Jung-Cheng Kang, Shee-Ping Chen, Po-Cheng Lin, Putzer-Joseph Hung, Jen-Ren Chen, Wen-Liang Chang, Shinn-Zong Lin and Horng-Jyh Harn
      Molecular Pharmacology October 2008, 74 (4) 1046-1058; DOI: https://doi.org/10.1124/mol.107.044800

  6. Lin, Po-Cheng

    1. The Induction of Orphan Nuclear Receptor Nur77 Expression by n-Butylenephthalide as Pharmaceuticals on Hepatocellular Carcinoma Cell Therapy
      Yi-Lin Chen, Min-Hui Jian, Chai-Ching Lin, Jung-Cheng Kang, Shee-Ping Chen, Po-Cheng Lin, Putzer-Joseph Hung, Jen-Ren Chen, Wen-Liang Chang, Shinn-Zong Lin and Horng-Jyh Harn
      Molecular Pharmacology October 2008, 74 (4) 1046-1058; DOI: https://doi.org/10.1124/mol.107.044800

  7. Lin, Shinn-Zong

    1. The Induction of Orphan Nuclear Receptor Nur77 Expression by n-Butylenephthalide as Pharmaceuticals on Hepatocellular Carcinoma Cell Therapy
      Yi-Lin Chen, Min-Hui Jian, Chai-Ching Lin, Jung-Cheng Kang, Shee-Ping Chen, Po-Cheng Lin, Putzer-Joseph Hung, Jen-Ren Chen, Wen-Liang Chang, Shinn-Zong Lin and Horng-Jyh Harn
      Molecular Pharmacology October 2008, 74 (4) 1046-1058; DOI: https://doi.org/10.1124/mol.107.044800

  8. Loiacono, Richard E.

    1. New Insights into the Function of M4 Muscarinic Acetylcholine Receptors Gained Using a Novel Allosteric Modulator and a DREADD (Designer Receptor Exclusively Activated by a Designer Drug)
      Vindhya Nawaratne, Katie Leach, Nur Suratman, Richard E. Loiacono, Christian C. Felder, Blaine N. Armbruster, Bryan L. Roth, Patrick M. Sexton and Arthur Christopoulos
      Molecular Pharmacology October 2008, 74 (4) 1119-1131; DOI: https://doi.org/10.1124/mol.108.049353

  9. Low, Malcolm J.

    1. Differential Activation and Trafficking of μ-Opioid Receptors in Brain Slices
      Seksiri Arttamangkul, Nidia Quillinan, Malcolm J. Low, Mark von Zastrow, John Pintar and John T. Williams
      Molecular Pharmacology October 2008, 74 (4) 972-979; DOI: https://doi.org/10.1124/mol.108.048512

  10. Lute, Brandon J.

    1. Syntaxin 1A Interaction with the Dopamine Transporter Promotes Amphetamine-Induced Dopamine Efflux
      Francesca Binda, Concetta Dipace, Erica Bowton, Sabrina D. Robertson, Brandon J. Lute, Jacob U. Fog, Minjia Zhang, Namita Sen, Roger J. Colbran, Margaret E. Gnegy, Ulrik Gether, Jonathan A. Javitch, Kevin Erreger and Aurelio Galli
      Molecular Pharmacology October 2008, 74 (4) 1101-1108; DOI: https://doi.org/10.1124/mol.108.048447

M

  1. Mackenzie, Peter I.

    1. Kinetic Modeling of the Interactions between 4-Methylumbelliferone, 1-Naphthol, and Zidovudine Glucuronidation by UDP-Glucuronosyltransferase 2B7 (UGT2B7) Provides Evidence for Multiple Substrate Binding and Effector Sites
      Verawan Uchaipichat, Aleksandra Galetin, J. Brian Houston, Peter I. Mackenzie, J. Andrew Williams and John O. Miners
      Molecular Pharmacology October 2008, 74 (4) 1152-1162; DOI: https://doi.org/10.1124/mol.108.048645

  2. Marien, Marc

    1. Paraxanthine, the Primary Metabolite of Caffeine, Provides Protection against Dopaminergic Cell Death via Stimulation of Ryanodine Receptor Channels
      Serge Guerreiro, Damien Toulorge, Etienne Hirsch, Marc Marien, Pierre Sokoloff and Patrick P. Michel
      Molecular Pharmacology October 2008, 74 (4) 980-989; DOI: https://doi.org/10.1124/mol.108.048207

  3. Meng, Jie

    1. Inhibition of Tumor Growth by Endohedral Metallofullerenol Nanoparticles Optimized as Reactive Oxygen Species Scavenger
      Jun-Jie Yin, Fang Lao, Jie Meng, Peter P. Fu, Yuliang Zhao, Gengmei Xing, Xueyun Gao, Baoyun Sun, Paul C. Wang, Chunying Chen and Xing-Jie Liang
      Molecular Pharmacology October 2008, 74 (4) 1132-1140; DOI: https://doi.org/10.1124/mol.108.048348

  4. Michel, Patrick P.

    1. Paraxanthine, the Primary Metabolite of Caffeine, Provides Protection against Dopaminergic Cell Death via Stimulation of Ryanodine Receptor Channels
      Serge Guerreiro, Damien Toulorge, Etienne Hirsch, Marc Marien, Pierre Sokoloff and Patrick P. Michel
      Molecular Pharmacology October 2008, 74 (4) 980-989; DOI: https://doi.org/10.1124/mol.108.048207

  5. Miners, John O.

    1. Kinetic Modeling of the Interactions between 4-Methylumbelliferone, 1-Naphthol, and Zidovudine Glucuronidation by UDP-Glucuronosyltransferase 2B7 (UGT2B7) Provides Evidence for Multiple Substrate Binding and Effector Sites
      Verawan Uchaipichat, Aleksandra Galetin, J. Brian Houston, Peter I. Mackenzie, J. Andrew Williams and John O. Miners
      Molecular Pharmacology October 2008, 74 (4) 1152-1162; DOI: https://doi.org/10.1124/mol.108.048645

  6. Monczor, Federico

    1. Histamine H2 Receptor Trafficking: Role of Arrestin, Dynamin, and Clathrin in Histamine H2 Receptor Internalization
      Natalia Fernandez, Federico Monczor, Alberto Baldi, Carlos Davio and Carina Shayo
      Molecular Pharmacology October 2008, 74 (4) 1109-1118; DOI: https://doi.org/10.1124/mol.108.045336

N

  1. Nakaki, Toshio

    1. Mitochondrial Complex I Inhibitor Rotenone Inhibits and Redistributes Vesicular Monoamine Transporter 2 via Nitration in Human Dopaminergic SH-SY5Y Cells
      Masahiko Watabe and Toshio Nakaki
      Molecular Pharmacology October 2008, 74 (4) 933-940; DOI: https://doi.org/10.1124/mol.108.048546

  2. Nawaratne, Vindhya

    1. New Insights into the Function of M4 Muscarinic Acetylcholine Receptors Gained Using a Novel Allosteric Modulator and a DREADD (Designer Receptor Exclusively Activated by a Designer Drug)
      Vindhya Nawaratne, Katie Leach, Nur Suratman, Richard E. Loiacono, Christian C. Felder, Blaine N. Armbruster, Bryan L. Roth, Patrick M. Sexton and Arthur Christopoulos
      Molecular Pharmacology October 2008, 74 (4) 1119-1131; DOI: https://doi.org/10.1124/mol.108.049353

  3. Nayeem, Naushaba

    1. Mutations to the Kainate Receptor Subunit GluR6 Binding Pocket That Selectively Affect Domoate Binding
      Yihong Zhang, Naushaba Nayeem and Tim Green
      Molecular Pharmacology October 2008, 74 (4) 1163-1169; DOI: https://doi.org/10.1124/mol.108.048819

O

  1. Oberhauser, Berndt

    1. Targeting Ceramide Metabolism with a Potent and Specific Ceramide Kinase Inhibitor
      Christine Graf, Martin Klumpp, Michael Habig, Philipp Rovina, Andreas Billich, Thomas Baumruker, Berndt Oberhauser and Frédéric Bornancin
      Molecular Pharmacology October 2008, 74 (4) 925-932; DOI: https://doi.org/10.1124/mol.108.048652

P

  1. Pendyala, Lakshmi

    1. Dysregulation of Purine Nucleotide Biosynthesis Pathways Modulates Cisplatin Cytotoxicity in Saccharomyces cerevisiae
      David Kowalski, Lakshmi Pendyala, Bertrand Daignan-Fornier, Stephen B. Howell and Ruea-Yea Huang
      Molecular Pharmacology October 2008, 74 (4) 1092-1100; DOI: https://doi.org/10.1124/mol.108.048256

  2. Pfeilschifter, Josef

    1. Keratinocyte-Derived Vascular Endothelial Growth Factor Biosynthesis Represents a Pleiotropic Side Effect of Peroxisome Proliferator-Activated Receptor-γ Agonist Troglitazone but Not Rosiglitazone and Involves Activation of p38 Mitogen-Activated Protein Kinase: Implications for Diabetes-Impaired Skin Repair
      Dana Schiefelbein, Oliver Seitz, Itamar Goren, Jan Philipp Dißmann, Helmut Schmidt, Malte Bachmann, Robert Sader, Gerd Geisslinger, Josef Pfeilschifter and Stefan Frank
      Molecular Pharmacology October 2008, 74 (4) 952-963; DOI: https://doi.org/10.1124/mol.108.049395

  3. Piascik, Michael T.

    1. The α1D-Adrenergic Receptor Induces Vascular Smooth Muscle Apoptosis via a p53-Dependent Mechanism
      Mary L. García-Cazarín, Jennifer L. Smith, Daret K. St. Clair and Michael T. Piascik
      Molecular Pharmacology October 2008, 74 (4) 1000-1007; DOI: https://doi.org/10.1124/mol.108.047993

  4. Pintar, John

    1. Differential Activation and Trafficking of μ-Opioid Receptors in Brain Slices
      Seksiri Arttamangkul, Nidia Quillinan, Malcolm J. Low, Mark von Zastrow, John Pintar and John T. Williams
      Molecular Pharmacology October 2008, 74 (4) 972-979; DOI: https://doi.org/10.1124/mol.108.048512

Q

  1. Qi, Tao

    1. Identification of N-Terminal Receptor Activity-Modifying Protein Residues Important for Calcitonin Gene-Related Peptide, Adrenomedullin, and Amylin Receptor Function
      Tao Qi, George Christopoulos, Richard J. Bailey, Arthur Christopoulos, Patrick M. Sexton and Debbie L. Hay
      Molecular Pharmacology October 2008, 74 (4) 1059-1071; DOI: https://doi.org/10.1124/mol.108.047142

  2. Quillinan, Nidia

    1. Differential Activation and Trafficking of μ-Opioid Receptors in Brain Slices
      Seksiri Arttamangkul, Nidia Quillinan, Malcolm J. Low, Mark von Zastrow, John Pintar and John T. Williams
      Molecular Pharmacology October 2008, 74 (4) 972-979; DOI: https://doi.org/10.1124/mol.108.048512

R

  1. Robertson, Sabrina D.

    1. Syntaxin 1A Interaction with the Dopamine Transporter Promotes Amphetamine-Induced Dopamine Efflux
      Francesca Binda, Concetta Dipace, Erica Bowton, Sabrina D. Robertson, Brandon J. Lute, Jacob U. Fog, Minjia Zhang, Namita Sen, Roger J. Colbran, Margaret E. Gnegy, Ulrik Gether, Jonathan A. Javitch, Kevin Erreger and Aurelio Galli
      Molecular Pharmacology October 2008, 74 (4) 1101-1108; DOI: https://doi.org/10.1124/mol.108.048447

  2. Rosenkilde, Mette M.

    1. Structural Motifs of Importance for the Constitutive Activity of the Orphan 7TM Receptor EBI2: Analysis of Receptor Activation in the Absence of an Agonist
      Tau Benned-Jensen and Mette M. Rosenkilde
      Molecular Pharmacology October 2008, 74 (4) 1008-1021; DOI: https://doi.org/10.1124/mol.108.049676

  3. Roth, Bryan L.

    1. New Insights into the Function of M4 Muscarinic Acetylcholine Receptors Gained Using a Novel Allosteric Modulator and a DREADD (Designer Receptor Exclusively Activated by a Designer Drug)
      Vindhya Nawaratne, Katie Leach, Nur Suratman, Richard E. Loiacono, Christian C. Felder, Blaine N. Armbruster, Bryan L. Roth, Patrick M. Sexton and Arthur Christopoulos
      Molecular Pharmacology October 2008, 74 (4) 1119-1131; DOI: https://doi.org/10.1124/mol.108.049353

  4. Rovina, Philipp

    1. Targeting Ceramide Metabolism with a Potent and Specific Ceramide Kinase Inhibitor
      Christine Graf, Martin Klumpp, Michael Habig, Philipp Rovina, Andreas Billich, Thomas Baumruker, Berndt Oberhauser and Frédéric Bornancin
      Molecular Pharmacology October 2008, 74 (4) 925-932; DOI: https://doi.org/10.1124/mol.108.048652

  5. Russel, Frans G. M.

    1. Functional Role of Arginine 375 in Transmembrane Helix 6 of Multidrug Resistance Protein 4 (MRP4/ABCC4)
      Azza A. K. El-Sheikh, Jeroen J. M. W. van den Heuvel, Elmar Krieger, Frans G. M. Russel and Jan B. Koenderink
      Molecular Pharmacology October 2008, 74 (4) 964-971; DOI: https://doi.org/10.1124/mol.107.043661

S

  1. Sader, Robert

    1. Keratinocyte-Derived Vascular Endothelial Growth Factor Biosynthesis Represents a Pleiotropic Side Effect of Peroxisome Proliferator-Activated Receptor-γ Agonist Troglitazone but Not Rosiglitazone and Involves Activation of p38 Mitogen-Activated Protein Kinase: Implications for Diabetes-Impaired Skin Repair
      Dana Schiefelbein, Oliver Seitz, Itamar Goren, Jan Philipp Dißmann, Helmut Schmidt, Malte Bachmann, Robert Sader, Gerd Geisslinger, Josef Pfeilschifter and Stefan Frank
      Molecular Pharmacology October 2008, 74 (4) 952-963; DOI: https://doi.org/10.1124/mol.108.049395

  2. Samarasinghe, Ranmal

    1. Selective Inhibition of Mitogen-Activated Protein Kinase Phosphatases by Zinc Accounts for Extracellular Signal-Regulated Kinase 1/2-Dependent Oxidative Neuronal Cell Death
      Yeung Ho, Ranmal Samarasinghe, Megan E. Knoch, Marcia Lewis, Elias Aizenman and Donald B. DeFranco
      Molecular Pharmacology October 2008, 74 (4) 1141-1151; DOI: https://doi.org/10.1124/mol.108.049064

  3. Sayer, Rachel

    1. Human Proximal Tubular Epithelium Actively Secretes but Does Not Retain Rosuvastatin
      Anja Verhulst, Rachel Sayer, Marc E. De Broe, Patrick C. D'Haese and Colin D. A. Brown
      Molecular Pharmacology October 2008, 74 (4) 1084-1091; DOI: https://doi.org/10.1124/mol.108.047647

  4. Schiefelbein, Dana

    1. Keratinocyte-Derived Vascular Endothelial Growth Factor Biosynthesis Represents a Pleiotropic Side Effect of Peroxisome Proliferator-Activated Receptor-γ Agonist Troglitazone but Not Rosiglitazone and Involves Activation of p38 Mitogen-Activated Protein Kinase: Implications for Diabetes-Impaired Skin Repair
      Dana Schiefelbein, Oliver Seitz, Itamar Goren, Jan Philipp Dißmann, Helmut Schmidt, Malte Bachmann, Robert Sader, Gerd Geisslinger, Josef Pfeilschifter and Stefan Frank
      Molecular Pharmacology October 2008, 74 (4) 952-963; DOI: https://doi.org/10.1124/mol.108.049395

  5. Schmidt, Helmut

    1. Keratinocyte-Derived Vascular Endothelial Growth Factor Biosynthesis Represents a Pleiotropic Side Effect of Peroxisome Proliferator-Activated Receptor-γ Agonist Troglitazone but Not Rosiglitazone and Involves Activation of p38 Mitogen-Activated Protein Kinase: Implications for Diabetes-Impaired Skin Repair
      Dana Schiefelbein, Oliver Seitz, Itamar Goren, Jan Philipp Dißmann, Helmut Schmidt, Malte Bachmann, Robert Sader, Gerd Geisslinger, Josef Pfeilschifter and Stefan Frank
      Molecular Pharmacology October 2008, 74 (4) 952-963; DOI: https://doi.org/10.1124/mol.108.049395

  6. Seitz, Oliver

    1. Keratinocyte-Derived Vascular Endothelial Growth Factor Biosynthesis Represents a Pleiotropic Side Effect of Peroxisome Proliferator-Activated Receptor-γ Agonist Troglitazone but Not Rosiglitazone and Involves Activation of p38 Mitogen-Activated Protein Kinase: Implications for Diabetes-Impaired Skin Repair
      Dana Schiefelbein, Oliver Seitz, Itamar Goren, Jan Philipp Dißmann, Helmut Schmidt, Malte Bachmann, Robert Sader, Gerd Geisslinger, Josef Pfeilschifter and Stefan Frank
      Molecular Pharmacology October 2008, 74 (4) 952-963; DOI: https://doi.org/10.1124/mol.108.049395

  7. Sen, Namita

    1. Syntaxin 1A Interaction with the Dopamine Transporter Promotes Amphetamine-Induced Dopamine Efflux
      Francesca Binda, Concetta Dipace, Erica Bowton, Sabrina D. Robertson, Brandon J. Lute, Jacob U. Fog, Minjia Zhang, Namita Sen, Roger J. Colbran, Margaret E. Gnegy, Ulrik Gether, Jonathan A. Javitch, Kevin Erreger and Aurelio Galli
      Molecular Pharmacology October 2008, 74 (4) 1101-1108; DOI: https://doi.org/10.1124/mol.108.048447

  8. Sexton, Patrick M.

    1. Identification of N-Terminal Receptor Activity-Modifying Protein Residues Important for Calcitonin Gene-Related Peptide, Adrenomedullin, and Amylin Receptor Function
      Tao Qi, George Christopoulos, Richard J. Bailey, Arthur Christopoulos, Patrick M. Sexton and Debbie L. Hay
      Molecular Pharmacology October 2008, 74 (4) 1059-1071; DOI: https://doi.org/10.1124/mol.108.047142
    2. New Insights into the Function of M4 Muscarinic Acetylcholine Receptors Gained Using a Novel Allosteric Modulator and a DREADD (Designer Receptor Exclusively Activated by a Designer Drug)
      Vindhya Nawaratne, Katie Leach, Nur Suratman, Richard E. Loiacono, Christian C. Felder, Blaine N. Armbruster, Bryan L. Roth, Patrick M. Sexton and Arthur Christopoulos
      Molecular Pharmacology October 2008, 74 (4) 1119-1131; DOI: https://doi.org/10.1124/mol.108.049353

  9. Shayo, Carina

    1. Histamine H2 Receptor Trafficking: Role of Arrestin, Dynamin, and Clathrin in Histamine H2 Receptor Internalization
      Natalia Fernandez, Federico Monczor, Alberto Baldi, Carlos Davio and Carina Shayo
      Molecular Pharmacology October 2008, 74 (4) 1109-1118; DOI: https://doi.org/10.1124/mol.108.045336

  10. Smith, Jennifer L.

    1. The α1D-Adrenergic Receptor Induces Vascular Smooth Muscle Apoptosis via a p53-Dependent Mechanism
      Mary L. García-Cazarín, Jennifer L. Smith, Daret K. St. Clair and Michael T. Piascik
      Molecular Pharmacology October 2008, 74 (4) 1000-1007; DOI: https://doi.org/10.1124/mol.108.047993

  11. Sokoloff, Pierre

    1. Paraxanthine, the Primary Metabolite of Caffeine, Provides Protection against Dopaminergic Cell Death via Stimulation of Ryanodine Receptor Channels
      Serge Guerreiro, Damien Toulorge, Etienne Hirsch, Marc Marien, Pierre Sokoloff and Patrick P. Michel
      Molecular Pharmacology October 2008, 74 (4) 980-989; DOI: https://doi.org/10.1124/mol.108.048207

  12. Sun, Baoyun

    1. Inhibition of Tumor Growth by Endohedral Metallofullerenol Nanoparticles Optimized as Reactive Oxygen Species Scavenger
      Jun-Jie Yin, Fang Lao, Jie Meng, Peter P. Fu, Yuliang Zhao, Gengmei Xing, Xueyun Gao, Baoyun Sun, Paul C. Wang, Chunying Chen and Xing-Jie Liang
      Molecular Pharmacology October 2008, 74 (4) 1132-1140; DOI: https://doi.org/10.1124/mol.108.048348

  13. Suratman, Nur

    1. New Insights into the Function of M4 Muscarinic Acetylcholine Receptors Gained Using a Novel Allosteric Modulator and a DREADD (Designer Receptor Exclusively Activated by a Designer Drug)
      Vindhya Nawaratne, Katie Leach, Nur Suratman, Richard E. Loiacono, Christian C. Felder, Blaine N. Armbruster, Bryan L. Roth, Patrick M. Sexton and Arthur Christopoulos
      Molecular Pharmacology October 2008, 74 (4) 1119-1131; DOI: https://doi.org/10.1124/mol.108.049353

T

  1. Tikhonov, Denis B.

    1. Access and Binding of Local Anesthetics in the Closed Sodium Channel
      Iva Bruhova, Denis B. Tikhonov and Boris S. Zhorov
      Molecular Pharmacology October 2008, 74 (4) 1033-1045; DOI: https://doi.org/10.1124/mol.108.049759

  2. Toulorge, Damien

    1. Paraxanthine, the Primary Metabolite of Caffeine, Provides Protection against Dopaminergic Cell Death via Stimulation of Ryanodine Receptor Channels
      Serge Guerreiro, Damien Toulorge, Etienne Hirsch, Marc Marien, Pierre Sokoloff and Patrick P. Michel
      Molecular Pharmacology October 2008, 74 (4) 980-989; DOI: https://doi.org/10.1124/mol.108.048207

U

  1. Uchaipichat, Verawan

    1. Kinetic Modeling of the Interactions between 4-Methylumbelliferone, 1-Naphthol, and Zidovudine Glucuronidation by UDP-Glucuronosyltransferase 2B7 (UGT2B7) Provides Evidence for Multiple Substrate Binding and Effector Sites
      Verawan Uchaipichat, Aleksandra Galetin, J. Brian Houston, Peter I. Mackenzie, J. Andrew Williams and John O. Miners
      Molecular Pharmacology October 2008, 74 (4) 1152-1162; DOI: https://doi.org/10.1124/mol.108.048645

V

  1. van den Heuvel, Jeroen J. M. W.

    1. Functional Role of Arginine 375 in Transmembrane Helix 6 of Multidrug Resistance Protein 4 (MRP4/ABCC4)
      Azza A. K. El-Sheikh, Jeroen J. M. W. van den Heuvel, Elmar Krieger, Frans G. M. Russel and Jan B. Koenderink
      Molecular Pharmacology October 2008, 74 (4) 964-971; DOI: https://doi.org/10.1124/mol.107.043661

  2. Verhulst, Anja

    1. Human Proximal Tubular Epithelium Actively Secretes but Does Not Retain Rosuvastatin
      Anja Verhulst, Rachel Sayer, Marc E. De Broe, Patrick C. D'Haese and Colin D. A. Brown
      Molecular Pharmacology October 2008, 74 (4) 1084-1091; DOI: https://doi.org/10.1124/mol.108.047647

  3. von Zastrow, Mark

    1. Differential Activation and Trafficking of μ-Opioid Receptors in Brain Slices
      Seksiri Arttamangkul, Nidia Quillinan, Malcolm J. Low, Mark von Zastrow, John Pintar and John T. Williams
      Molecular Pharmacology October 2008, 74 (4) 972-979; DOI: https://doi.org/10.1124/mol.108.048512

W

  1. Wang, Paul C.

    1. Inhibition of Tumor Growth by Endohedral Metallofullerenol Nanoparticles Optimized as Reactive Oxygen Species Scavenger
      Jun-Jie Yin, Fang Lao, Jie Meng, Peter P. Fu, Yuliang Zhao, Gengmei Xing, Xueyun Gao, Baoyun Sun, Paul C. Wang, Chunying Chen and Xing-Jie Liang
      Molecular Pharmacology October 2008, 74 (4) 1132-1140; DOI: https://doi.org/10.1124/mol.108.048348

  2. Watabe, Masahiko

    1. Mitochondrial Complex I Inhibitor Rotenone Inhibits and Redistributes Vesicular Monoamine Transporter 2 via Nitration in Human Dopaminergic SH-SY5Y Cells
      Masahiko Watabe and Toshio Nakaki
      Molecular Pharmacology October 2008, 74 (4) 933-940; DOI: https://doi.org/10.1124/mol.108.048546

  3. Williams, J. Andrew

    1. Kinetic Modeling of the Interactions between 4-Methylumbelliferone, 1-Naphthol, and Zidovudine Glucuronidation by UDP-Glucuronosyltransferase 2B7 (UGT2B7) Provides Evidence for Multiple Substrate Binding and Effector Sites
      Verawan Uchaipichat, Aleksandra Galetin, J. Brian Houston, Peter I. Mackenzie, J. Andrew Williams and John O. Miners
      Molecular Pharmacology October 2008, 74 (4) 1152-1162; DOI: https://doi.org/10.1124/mol.108.048645

  4. Williams, John T.

    1. Differential Activation and Trafficking of μ-Opioid Receptors in Brain Slices
      Seksiri Arttamangkul, Nidia Quillinan, Malcolm J. Low, Mark von Zastrow, John Pintar and John T. Williams
      Molecular Pharmacology October 2008, 74 (4) 972-979; DOI: https://doi.org/10.1124/mol.108.048512

X

  1. Xing, Gengmei

    1. Inhibition of Tumor Growth by Endohedral Metallofullerenol Nanoparticles Optimized as Reactive Oxygen Species Scavenger
      Jun-Jie Yin, Fang Lao, Jie Meng, Peter P. Fu, Yuliang Zhao, Gengmei Xing, Xueyun Gao, Baoyun Sun, Paul C. Wang, Chunying Chen and Xing-Jie Liang
      Molecular Pharmacology October 2008, 74 (4) 1132-1140; DOI: https://doi.org/10.1124/mol.108.048348

  2. Xue, Fenqin

    1. Structural Determinants for Antagonist Pharmacology That Distinguish the ρ1 GABAC Receptor from GABAA Receptors
      Jianliang Zhang, Fenqin Xue and Yongchang Chang
      Molecular Pharmacology October 2008, 74 (4) 941-951; DOI: https://doi.org/10.1124/mol.108.048710

Y

  1. Yin, Jun-Jie

    1. Inhibition of Tumor Growth by Endohedral Metallofullerenol Nanoparticles Optimized as Reactive Oxygen Species Scavenger
      Jun-Jie Yin, Fang Lao, Jie Meng, Peter P. Fu, Yuliang Zhao, Gengmei Xing, Xueyun Gao, Baoyun Sun, Paul C. Wang, Chunying Chen and Xing-Jie Liang
      Molecular Pharmacology October 2008, 74 (4) 1132-1140; DOI: https://doi.org/10.1124/mol.108.048348

Z

  1. Zhang, Jianliang

    1. Structural Determinants for Antagonist Pharmacology That Distinguish the ρ1 GABAC Receptor from GABAA Receptors
      Jianliang Zhang, Fenqin Xue and Yongchang Chang
      Molecular Pharmacology October 2008, 74 (4) 941-951; DOI: https://doi.org/10.1124/mol.108.048710

  2. Zhang, Minjia

    1. Syntaxin 1A Interaction with the Dopamine Transporter Promotes Amphetamine-Induced Dopamine Efflux
      Francesca Binda, Concetta Dipace, Erica Bowton, Sabrina D. Robertson, Brandon J. Lute, Jacob U. Fog, Minjia Zhang, Namita Sen, Roger J. Colbran, Margaret E. Gnegy, Ulrik Gether, Jonathan A. Javitch, Kevin Erreger and Aurelio Galli
      Molecular Pharmacology October 2008, 74 (4) 1101-1108; DOI: https://doi.org/10.1124/mol.108.048447

  3. Zhang, Yihong

    1. Mutations to the Kainate Receptor Subunit GluR6 Binding Pocket That Selectively Affect Domoate Binding
      Yihong Zhang, Naushaba Nayeem and Tim Green
      Molecular Pharmacology October 2008, 74 (4) 1163-1169; DOI: https://doi.org/10.1124/mol.108.048819

  4. Zhao, Yuliang

    1. Inhibition of Tumor Growth by Endohedral Metallofullerenol Nanoparticles Optimized as Reactive Oxygen Species Scavenger
      Jun-Jie Yin, Fang Lao, Jie Meng, Peter P. Fu, Yuliang Zhao, Gengmei Xing, Xueyun Gao, Baoyun Sun, Paul C. Wang, Chunying Chen and Xing-Jie Liang
      Molecular Pharmacology October 2008, 74 (4) 1132-1140; DOI: https://doi.org/10.1124/mol.108.048348

  5. Zhorov, Boris S.

    1. Access and Binding of Local Anesthetics in the Closed Sodium Channel
      Iva Bruhova, Denis B. Tikhonov and Boris S. Zhorov
      Molecular Pharmacology October 2008, 74 (4) 1033-1045; DOI: https://doi.org/10.1124/mol.108.049759
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