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Research ArticleArticle

Identification of a Putative Intracellular Allosteric Antagonist Binding-Site in the CXC Chemokine Receptors 1 and 2

David J. Nicholls, Nick P. Tomkinson, Katherine E. Wiley, Anne Brammall, Lorna Bowers, Caroline Grahames, Alasdair Gaw, Premji Meghani, Philip Shelton, Tracey J. Wright and Philip R. Mallinder
Molecular Pharmacology November 2008, 74 (5) 1193-1202; DOI: https://doi.org/10.1124/mol.107.044610

Article Information

vol. 74 no. 5 1193-1202
DOI 
https://doi.org/10.1124/mol.107.044610
PubMed 
18676678
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received December 21, 2007
  • Accepted August 1, 2008
  • Published online October 20, 2008.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. David J. Nicholls,
  2. Nick P. Tomkinson,
  3. Katherine E. Wiley,
  4. Anne Brammall,
  5. Lorna Bowers,
  6. Caroline Grahames,
  7. Alasdair Gaw,
  8. Premji Meghani,
  9. Philip Shelton,
  10. Tracey J. Wright1 and
  11. Philip R. Mallinder
  1. Respiratory and Inflammation Research Area, AstraZeneca Research and Development, Loughborough, United Kingdom
  1. Address correspondence to:
    Dr. David J. Nicholls, Department of Discovery BioScience, AstraZeneca R&D Charnwood, Bakewell Road, Loughborough, Leicestershire LE11 5RH, United Kingdom. E-mail: david.nicholls{at}astrazeneca.com
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Research ArticleArticle

Identification of a Putative Intracellular Allosteric Antagonist Binding-Site in the CXC Chemokine Receptors 1 and 2

David J. Nicholls, Nick P. Tomkinson, Katherine E. Wiley, Anne Brammall, Lorna Bowers, Caroline Grahames, Alasdair Gaw, Premji Meghani, Philip Shelton, Tracey J. Wright and Philip R. Mallinder
Molecular Pharmacology November 1, 2008, 74 (5) 1193-1202; DOI: https://doi.org/10.1124/mol.107.044610
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