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Research ArticleArticle

Identification of a Putative Intracellular Allosteric Antagonist Binding-Site in the CXC Chemokine Receptors 1 and 2

David J. Nicholls, Nick P. Tomkinson, Katherine E. Wiley, Anne Brammall, Lorna Bowers, Caroline Grahames, Alasdair Gaw, Premji Meghani, Philip Shelton, Tracey J. Wright and Philip R. Mallinder
Molecular Pharmacology November 2008, 74 (5) 1193-1202; DOI: https://doi.org/10.1124/mol.107.044610
David J. Nicholls
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Nick P. Tomkinson
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Katherine E. Wiley
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Anne Brammall
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Lorna Bowers
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Caroline Grahames
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Alasdair Gaw
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Premji Meghani
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Philip Shelton
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Tracey J. Wright
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Philip R. Mallinder
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Article Information

vol. 74 no. 5 1193-1202
DOI 
https://doi.org/10.1124/mol.107.044610
PubMed 
18676678

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received December 21, 2007
  • Accepted August 1, 2008
  • Published online October 20, 2008.

Article Versions

  • Earlier version (August 1, 2008 - 08:12).
  • Earlier version (August 19, 2008 - 09:09).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. David J. Nicholls,
  2. Nick P. Tomkinson,
  3. Katherine E. Wiley,
  4. Anne Brammall,
  5. Lorna Bowers,
  6. Caroline Grahames,
  7. Alasdair Gaw,
  8. Premji Meghani,
  9. Philip Shelton,
  10. Tracey J. Wright1 and
  11. Philip R. Mallinder
  1. Respiratory and Inflammation Research Area, AstraZeneca Research and Development, Loughborough, United Kingdom
  1. Address correspondence to:
    Dr. David J. Nicholls, Department of Discovery BioScience, AstraZeneca R&D Charnwood, Bakewell Road, Loughborough, Leicestershire LE11 5RH, United Kingdom. E-mail: david.nicholls{at}astrazeneca.com
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Molecular Pharmacology: 74 (5)
Molecular Pharmacology
Vol. 74, Issue 5
1 Nov 2008
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Research ArticleArticle

Identification of a Putative Intracellular Allosteric Antagonist Binding-Site in the CXC Chemokine Receptors 1 and 2

David J. Nicholls, Nick P. Tomkinson, Katherine E. Wiley, Anne Brammall, Lorna Bowers, Caroline Grahames, Alasdair Gaw, Premji Meghani, Philip Shelton, Tracey J. Wright and Philip R. Mallinder
Molecular Pharmacology November 1, 2008, 74 (5) 1193-1202; DOI: https://doi.org/10.1124/mol.107.044610

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Research ArticleArticle

Identification of a Putative Intracellular Allosteric Antagonist Binding-Site in the CXC Chemokine Receptors 1 and 2

David J. Nicholls, Nick P. Tomkinson, Katherine E. Wiley, Anne Brammall, Lorna Bowers, Caroline Grahames, Alasdair Gaw, Premji Meghani, Philip Shelton, Tracey J. Wright and Philip R. Mallinder
Molecular Pharmacology November 1, 2008, 74 (5) 1193-1202; DOI: https://doi.org/10.1124/mol.107.044610
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