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Molecular Pharmacology

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Table of Contents

January 01, 2009; Volume 75,Issue 1

MINIREVIEW

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    Topology of Class A G Protein-Coupled Receptors: Insights Gained from Crystal Structures of Rhodopsins, Adrenergic and Adenosine Receptors
    Debarshi Mustafi and Krzysztof Palczewski
    Molecular Pharmacology January 2009, 75 (1) 1-12; DOI: https://doi.org/10.1124/mol.108.051938

Perspective

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    Functional Selectivity of GPCR Ligand Stereoisomers: New Pharmacological Opportunities
    Roland Seifert and Stefan Dove
    Molecular Pharmacology January 2009, 75 (1) 13-18; DOI: https://doi.org/10.1124/mol.108.052944

Articles

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    An Intracellular Loop 2 Amino Acid Residue Determines Differential Binding of Arrestin to the Dopamine D2 and D3 Receptors
    Hongxiang Lan, Martha M. Teeter, Vsevolod V. Gurevich and Kim A. Neve
    Molecular Pharmacology January 2009, 75 (1) 19-26; DOI: https://doi.org/10.1124/mol.108.050542
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    Hydrogen Sulfide Inhibits Rotenone-Induced Apoptosis via Preservation of Mitochondrial Function
    Li-Fang Hu, Ming Lu, Zhi-Yuan Wu, Peter T.-H. Wong and Jin-Song Bian
    Molecular Pharmacology January 2009, 75 (1) 27-34; DOI: https://doi.org/10.1124/mol.108.047985
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    Suppression of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Nitric-Oxide Synthase 2 Expression in Astrocytes by a Novel Diindolylmethane Analog Protects Striatal Neurons against Apoptosis
    David. L. Carbone, Katriana A. Popichak, Julie A. Moreno, Stephen Safe and Ronald B. Tjalkens
    Molecular Pharmacology January 2009, 75 (1) 35-43; DOI: https://doi.org/10.1124/mol.108.050781
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    Overlapping Binding Site for the Endogenous Agonist, Small-Molecule Agonists, and Ago-allosteric Modulators on the Ghrelin Receptor
    Birgitte Holst, Thomas M. Frimurer, Jacek Mokrosinski, Tine Halkjaer, Karina B. Cullberg, Christina R. Underwood and Thue W. Schwartz
    Molecular Pharmacology January 2009, 75 (1) 44-59; DOI: https://doi.org/10.1124/mol.108.049189
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    Structural Basis of NR2B-Selective Antagonist Recognition by N-Methyl-d-aspartate Receptors
    Laetitia Mony, Lucie Krzaczkowski, Manuel Leonetti, Anne Le Goff, Karine Alarcon, Jacques Neyton, Hughes-Olivier Bertrand, Francine Acher and Pierre Paoletti
    Molecular Pharmacology January 2009, 75 (1) 60-74; DOI: https://doi.org/10.1124/mol.108.050971
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    Imatinib Mesylate (STI571)-Induced Cell Edge Translocation of Kinase-Active and Kinase-Defective Abelson Kinase: Requirements of Myristoylation and src Homology 3 Domain
    Akiko Fujita, Tomoyuki Shishido, Yunfeng Yuan, Eiji Inamoto, Shuh Narumiya and Naoki Watanabe
    Molecular Pharmacology January 2009, 75 (1) 75-84; DOI: https://doi.org/10.1124/mol.108.051706
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    Flow Cytometry-Based Binding Assay for GPR40 (FFAR1; Free Fatty Acid Receptor 1)
    Takafumi Hara, Akira Hirasawa, Qi Sun, Taka-aki Koshimizu, Chisato Itsubo, Keiko Sadakane, Takeo Awaji and Gozoh Tsujimoto
    Molecular Pharmacology January 2009, 75 (1) 85-91; DOI: https://doi.org/10.1124/mol.108.052225
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    Inhibition of P-Glycoprotein-Mediated Paclitaxel Resistance by Reversibly Linked Quinine Homodimers
    Marcos M. Pires, Dana Emmert, Christine A. Hrycyna and Jean Chmielewski
    Molecular Pharmacology January 2009, 75 (1) 92-100; DOI: https://doi.org/10.1124/mol.108.050492
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    Phenylephrine-Induced Cardiomyocyte Injury Is Triggered by Superoxide Generation through Uncoupled Endothelial Nitric-Oxide Synthase and Ameliorated by 3-[2-[4-(3-Chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxyindazole (DY-9836), a Novel Calmodulin Antagonist
    Ying-Mei Lu, Feng Han, Norifumi Shioda, Shigeki Moriguchi, Yasufumi Shirasaki, Zheng-Hong Qin and Kohji Fukunaga
    Molecular Pharmacology January 2009, 75 (1) 101-112; DOI: https://doi.org/10.1124/mol.108.050716
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    A Dopamine D2 Receptor Mutant Capable of G Protein-Mediated Signaling but Deficient in Arrestin Binding
    Hongxiang Lan, Yong Liu, Michal I. Bell, Vsevolod V. Gurevich and Kim A. Neve
    Molecular Pharmacology January 2009, 75 (1) 113-123; DOI: https://doi.org/10.1124/mol.108.050534
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    90-kDa Heat Shock Protein Inhibition Abrogates the Topoisomerase I Poison-Induced G2/M Checkpoint in p53-Null Tumor Cells by Depleting Chk1 and Wee1
    Archie N. Tse, Tahir N. Sheikh, Ho Alan, Ting-Chao Chou and Gary K. Schwartz
    Molecular Pharmacology January 2009, 75 (1) 124-133; DOI: https://doi.org/10.1124/mol.108.050807
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    Thiophenecarboxylate Suppressor of Cyclic Nucleotides Discovered in a Small-Molecule Screen Blocks Toxin-Induced Intestinal Fluid Secretion
    Lukmanee Tradtrantip, Buranee Yangthara, Prashant Padmawar, Christopher Morrison and A. S. Verkman
    Molecular Pharmacology January 2009, 75 (1) 134-142; DOI: https://doi.org/10.1124/mol.108.050567
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    Short-Chain Ubiquitination Is Associated with the Degradation Rate of a Cell-Surface-Resident Bile Salt Export Pump (BSEP/ABCB11)
    Hisamitsu Hayashi and Yuichi Sugiyama
    Molecular Pharmacology January 2009, 75 (1) 143-150; DOI: https://doi.org/10.1124/mol.108.049288
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    Vanillin Inhibits Matrix Metalloproteinase-9 Expression through Down-Regulation of Nuclear Factor-κB Signaling Pathway in Human Hepatocellular Carcinoma Cells
    Ji-An Liang, Shih-Lu Wu, Hsin-Yi Lo, Chien-Yun Hsiang and Tin-Yun Ho
    Molecular Pharmacology January 2009, 75 (1) 151-157; DOI: https://doi.org/10.1124/mol.108.049502
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    Stereochemistry of an Agonist Determines Coupling Preference of β2-Adrenoceptor to Different G Proteins in Cardiomyocytes
    Anthony Yiu-Ho Woo, Tian-Bing Wang, Xiaokun Zeng, Weizhong Zhu, Darrell R. Abernethy, Irving W. Wainer and Rui-Ping Xiao
    Molecular Pharmacology January 2009, 75 (1) 158-165; DOI: https://doi.org/10.1124/mol.108.051078
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    Site Selectivity of Competitive Antagonists for the Mouse Adult Muscle Nicotinic Acetylcholine Receptor
    Man Liu and James P. Dilger
    Molecular Pharmacology January 2009, 75 (1) 166-173; DOI: https://doi.org/10.1124/mol.108.051060
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    Copper Regulation of Hypoxia-Inducible Factor-1 Activity
    Wenke Feng, Fei Ye, Wanli Xue, Zhanxiang Zhou and Y. James Kang
    Molecular Pharmacology January 2009, 75 (1) 174-182; DOI: https://doi.org/10.1124/mol.108.051516
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    Amitriptyline Activates Cardiac Ryanodine Channels and Causes Spontaneous Sarcoplasmic Reticulum Calcium Release
    Nagesh Chopra, Derek Laver, Sean S. Davies and Björn C. Knollmann
    Molecular Pharmacology January 2009, 75 (1) 183-195; DOI: https://doi.org/10.1124/mol.108.051490
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    Fibroblast Growth Factor (FGF) and FGF Receptor-Mediated Autocrine Signaling in Non-Small-Cell Lung Cancer Cells
    Lindsay Marek, Kathryn E. Ware, Alexa Fritzsche, Paula Hercule, Wallace R. Helton, Jennifer E. Smith, Lee A. McDermott, Christopher D. Coldren, Raphael A. Nemenoff, Daniel T. Merrick, Barbara A. Helfrich, Paul A. Bunn and Lynn E. Heasley
    Molecular Pharmacology January 2009, 75 (1) 196-207; DOI: https://doi.org/10.1124/mol.108.049544
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    YC-1 Stimulates the Expression of Gaseous Monoxide-Generating Enzymes in Vascular Smooth Muscle Cells
    Xiao-ming Liu, Kelly J. Peyton, Natalia N. Mendelev, Hong Wang, David A. Tulis and William Durante
    Molecular Pharmacology January 2009, 75 (1) 208-217; DOI: https://doi.org/10.1124/mol.108.048314
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    Intracellular Activation and Deactivation of Tasidotin, an Analog of Dolastatin 15: Correlation with Cytotoxicity
    Ruoli Bai, Michael C. Edler, Peter L. Bonate, Terry D. Copeland, George R. Pettit, Richard F. Ludueña and Ernest Hamel
    Molecular Pharmacology January 2009, 75 (1) 218-226; DOI: https://doi.org/10.1124/mol.108.051110
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    Opposing Effects of Platelet-Activating Factor and Lyso-Platelet-Activating Factor on Neutrophil and Platelet Activation
    Emily J. Welch, Ram P. Naikawadi, Zhenyu Li, Phoebe Lin, Satoshi Ishii, Takao Shimizu, Chinnaswamy Tiruppathi, Xiaoping Du, Papasani V. Subbaiah and Richard D. Ye
    Molecular Pharmacology January 2009, 75 (1) 227-234; DOI: https://doi.org/10.1124/mol.108.051003
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    The Gq and G12 Families of Heterotrimeric G Proteins Report Functional Selectivity
    Li Zhang, Lawrence F. Brass and David R. Manning
    Molecular Pharmacology January 2009, 75 (1) 235-241; DOI: https://doi.org/10.1124/mol.108.050906
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    Inhibition of Arachidonic Acid and Iron-Induced Mitochondrial Dysfunction and Apoptosis by Oltipraz and Novel 1,2-Dithiole-3-thione Congeners
    Sang Mi Shin and Sang Geon Kim
    Molecular Pharmacology January 2009, 75 (1) 242-253; DOI: https://doi.org/10.1124/mol.108.051128

Errata

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    Correction to “The NR1 M3 Domain Mediates Allosteric Coupling in the N-Methyl-d-aspartate Receptor”
    Molecular Pharmacology January 2009, 75 (1) 254-257; DOI: https://doi.org/10.1124/mol.75.1.254
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    Correction to “Inhibitors of GlyT1 Affect Glycine Transport via Discrete Binding Sites”
    Molecular Pharmacology January 2009, 75 (1) 258; DOI: https://doi.org/10.1124/mol.75.1.258
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    Correction to Table of Contents (Volume 74, Number 6, December 2008)
    Molecular Pharmacology January 2009, 75 (1) 258; DOI: https://doi.org/10.1124/mol.75.1.258-a
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In this issue

Molecular Pharmacology: 75 (1)
Molecular Pharmacology
Vol. 75, Issue 1
1 Jan 2009
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