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Research ArticleArticle

Amitriptyline Activates Cardiac Ryanodine Channels and Causes Spontaneous Sarcoplasmic Reticulum Calcium Release

Nagesh Chopra, Derek Laver, Sean S. Davies and Björn C. Knollmann
Molecular Pharmacology January 2009, 75 (1) 183-195; DOI: https://doi.org/10.1124/mol.108.051490
Nagesh Chopra
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Derek Laver
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Sean S. Davies
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Björn C. Knollmann
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Article Information

vol. 75 no. 1 183-195
DOI 
https://doi.org/10.1124/mol.108.051490
PubMed 
18845675

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received August 19, 2008
  • Accepted October 8, 2008
  • Published online December 19, 2008.

Article Versions

  • Earlier version (October 9, 2008 - 10:26).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Nagesh Chopra,
  2. Derek Laver,
  3. Sean S. Davies and
  4. Björn C. Knollmann
  1. Oates Institute for Experimental Therapeutics and Division of Clinical Pharmacology, Departments of Medicine and Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee (N.C., S.S.D., B.C.K.); and Department of Biomedical Sciences, University of Newcastle and HMRI, Callaghan, Australia (D.L.).
  1. Address correspondence to:
    Dr. Björn C. Knollmann, Oates Institute for Experimental Therapeutics, Division of Clinical Pharmacology, Vanderbilt University Medical Center, 1265 Medical Research Building IV, Nashville, TN 37232-0575. E-mail: bjorn.knollmann{at}vanderbilt.edu
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Molecular Pharmacology: 75 (1)
Molecular Pharmacology
Vol. 75, Issue 1
1 Jan 2009
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Research ArticleArticle

Amitriptyline Activates Cardiac Ryanodine Channels and Causes Spontaneous Sarcoplasmic Reticulum Calcium Release

Nagesh Chopra, Derek Laver, Sean S. Davies and Björn C. Knollmann
Molecular Pharmacology January 1, 2009, 75 (1) 183-195; DOI: https://doi.org/10.1124/mol.108.051490

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Research ArticleArticle

Amitriptyline Activates Cardiac Ryanodine Channels and Causes Spontaneous Sarcoplasmic Reticulum Calcium Release

Nagesh Chopra, Derek Laver, Sean S. Davies and Björn C. Knollmann
Molecular Pharmacology January 1, 2009, 75 (1) 183-195; DOI: https://doi.org/10.1124/mol.108.051490
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