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Molecular Pharmacology

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Table of Contents

February 01, 2009; Volume 75,Issue 2

MINIREVIEW

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    Regulation of the Mammalian Nervous System by MicroRNAs
    Yan Zeng
    Molecular Pharmacology February 2009, 75 (2) 259-264; DOI: https://doi.org/10.1124/mol.108.052118

Accelerated Communications

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    Nuclear Xenobiotic Receptor Pregnane X Receptor Locks Corepressor Silencing Mediator for Retinoid and Thyroid Hormone Receptors (SMRT) onto the CYP24A1 Promoter to Attenuate Vitamin D3 Activation
    Yoshihiro Konno, Susumu Kodama, Rick Moore, Nobuhiro Kamiya and Masahiko Negishi
    Molecular Pharmacology February 2009, 75 (2) 265-271; DOI: https://doi.org/10.1124/mol.108.051904
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    Refinement of the Binding Site and Mode of Action of the Anticonvulsant Retigabine on KCNQ K+ Channels
    Wienke Lange, Jan Geißendörfer, Anne Schenzer, Joachim Grötzinger, Guiscard Seebohm, Thomas Friedrich and Michael Schwake
    Molecular Pharmacology February 2009, 75 (2) 272-280; DOI: https://doi.org/10.1124/mol.108.052282

Articles

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    Naphtho[1,2-d]thiazol-2-ylamine (SKA-31), a New Activator of KCa2 and KCa3.1 Potassium Channels, Potentiates the Endothelium-Derived Hyperpolarizing Factor Response and Lowers Blood Pressure
    Ananthakrishnan Sankaranarayanan, Girija Raman, Christoph Busch, Tim Schultz, Pavel I. Zimin, Joachim Hoyer, Ralf Köhler and Heike Wulff
    Molecular Pharmacology February 2009, 75 (2) 281-295; DOI: https://doi.org/10.1124/mol.108.051425
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    Molecular Characterization of Novel and Selective Peroxisome Proliferator-Activated Receptor α Agonists with Robust Hypolipidemic Activity in Vivo
    Christopher D. Kane, Kimberly A. Stevens, James E. Fischer, Mehrdad Haghpassand, Lori J. Royer, Charles Aldinger, Katherine T. Landschulz, Panayiotis Zagouras, Scott W. Bagley, William Hada, Robert Dullea, Cheryl M. Hayward and Omar L. Francone
    Molecular Pharmacology February 2009, 75 (2) 296-306; DOI: https://doi.org/10.1124/mol.108.051656
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    Involvement of Transient Receptor Potential Vanilloid Subtype 1 in Analgesic Action of Methylsalicylate
    Toshio Ohta, Toshiaki Imagawa and Shigeo Ito
    Molecular Pharmacology February 2009, 75 (2) 307-317; DOI: https://doi.org/10.1124/mol.108.051292
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    Thermostable Variants of Cocaine Esterase for Long-Time Protection against Cocaine Toxicity
    Daquan Gao, Diwahar L. Narasimhan, Joanne Macdonald, Remy Brim, Mei-Chuan Ko, Donald W. Landry, James H. Woods, Roger K. Sunahara and Chang-Guo Zhan
    Molecular Pharmacology February 2009, 75 (2) 318-323; DOI: https://doi.org/10.1124/mol.108.049486
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    The Role of the Mammalian Copper Transporter 1 in the Cellular Accumulation of Platinum-Based Drugs
    Christopher A. Larson, Brian G. Blair, Roohangiz Safaei and Stephen B. Howell
    Molecular Pharmacology February 2009, 75 (2) 324-330; DOI: https://doi.org/10.1124/mol.108.052381
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    Mutagenic Mapping Suggests a Novel Binding Mode for Selective Agonists of M1 Muscarinic Acetylcholine Receptors
    Guillaume Lebon, Christopher J. Langmead, Ben G. Tehan and Edward C. Hulme
    Molecular Pharmacology February 2009, 75 (2) 331-341; DOI: https://doi.org/10.1124/mol.108.050963
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    The Reelin and GAD67 Promoters Are Activated by Epigenetic Drugs That Facilitate the Disruption of Local Repressor Complexes
    Marija Kundakovic, Ying Chen, Alessandro Guidotti and Dennis R. Grayson
    Molecular Pharmacology February 2009, 75 (2) 342-354; DOI: https://doi.org/10.1124/mol.108.051763
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    Allosteric LFA-1 Inhibitors Modulate Natural Killer Cell Function
    Gabriele Weitz-Schmidt, Stéphanie Chreng and Simone Riek
    Molecular Pharmacology February 2009, 75 (2) 355-362; DOI: https://doi.org/10.1124/mol.108.051169
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    Preferential Physical and Functional Interaction of Pregnane X Receptor with the SMRTα Isoform
    Chia-Wei Li, Gia Khanh Dinh and J. Don Chen
    Molecular Pharmacology February 2009, 75 (2) 363-373; DOI: https://doi.org/10.1124/mol.108.047845
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    Pharmacological Analysis of the Novel, Rapid, and Potent Inactivation of the Human 5-Hydroxytryptamine7 Receptor by Risperidone, 9-OH-Risperidone, and Other Inactivating Antagonists
    Jessica A. Knight, Carol Smith, Nicole Toohey, Michael T. Klein and Milt Teitler
    Molecular Pharmacology February 2009, 75 (2) 374-380; DOI: https://doi.org/10.1124/mol.108.052084
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    Estimation of Relative Microscopic Affinity Constants of Agonists for the Active State of the Receptor in Functional Studies on M2 and M3 Muscarinic Receptors
    John A. Tran, Alexander Chang, Minoru Matsui and Frederick J. Ehlert
    Molecular Pharmacology February 2009, 75 (2) 381-396; DOI: https://doi.org/10.1124/mol.108.051276
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    Multiple Roles of Charged Amino Acids in Cytoplasmic Loop 7 for Expression and Function of the Multidrug and Organic Anion Transporter MRP1 (ABCC1)
    Gwenaëlle Conseil, Alice J. Rothnie, Roger G. Deeley and Susan P. C. Cole
    Molecular Pharmacology February 2009, 75 (2) 397-406; DOI: https://doi.org/10.1124/mol.108.052860
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    Expression and 1,4-Dihydropyridine-Binding Properties of Brain L-Type Calcium Channel Isoforms
    Martina J. Sinnegger-Brauns, Irene G. Huber, Alexandra Koschak, Claudia Wild, Gerald J Obermair, Ursula Einzinger, Jean-Charles Hoda, Simone B. Sartori and Jörg Striessnig
    Molecular Pharmacology February 2009, 75 (2) 407-414; DOI: https://doi.org/10.1124/mol.108.049981
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    Relaxin Family Peptide Receptor (RXFP1) Coupling to Gαi3 Involves the C-Terminal Arg752 and Localization within Membrane Raft Microdomains
    Michelle L. Halls, Emma T. van der Westhuizen, John D. Wade, Bronwyn A. Evans, Ross A. D. Bathgate and Roger J. Summers
    Molecular Pharmacology February 2009, 75 (2) 415-428; DOI: https://doi.org/10.1124/mol.108.051227
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In this issue

Molecular Pharmacology: 75 (2)
Molecular Pharmacology
Vol. 75, Issue 2
1 Feb 2009
  • Table of Contents
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  • Back Matter (PDF)
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  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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