Table of Contents

Articles

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  Lithium Increases Synapse Formation between Hippocampal Neurons by Depleting Phosphoinositides

  Hee Jung Kim and Stanley A. Thayer

  Molecular Pharmacology May 2009, 75 (5) 1021-1030; DOI: https://doi.org/10.1124/mol.108.052357
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  Mitogen-Activated Protein Kinase Pathways Contribute to Hypercontractility and Increased Ca²⁺ Sensitization in Murine Experimental Colitis

  Eikichi Ihara, Paul L. Beck, Mona Chappellaz, Josee Wong, Shaun A. Medlicott and Justin A. MacDonald

  Molecular Pharmacology May 2009, 75 (5) 1031-1041; DOI: https://doi.org/10.1124/mol.108.049858
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  A Small Peptide Inhibitor of the Low Voltage-Activated Calcium Channel Cav3.1

  Ren-Shiang Chen and Philip M. Best

  Molecular Pharmacology May 2009, 75 (5) 1042-1051; DOI: https://doi.org/10.1124/mol.108.052654
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  Antidepressant Phenelzine Alters Differentiation of Cultured Human and Mouse Preadipocytes

  Françoise Chiche, Morwenna Le Guillou, Gérard Chétrite, Françoise Lasnier, Isabelle Dugail, Christian Carpéné, Marthe Moldes and Bruno Fève

  Molecular Pharmacology May 2009, 75 (5) 1052-1061; DOI: https://doi.org/10.1124/mol.108.052563
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  The Four Major N- and C-Terminal Splice Variants of the Excitatory Amino Acid Transporter GLT-1 Form Cell Surface Homomeric and Heteromeric Assemblies

  Eleanor Peacey, Christopher C. J. Miller, John Dunlop and Marcus Rattray

  Molecular Pharmacology May 2009, 75 (5) 1062-1073; DOI: https://doi.org/10.1124/mol.108.052829
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  KiSS1 Metastasis Suppressor Gene Product Induces Suppression of Tyrosine Kinase Receptor Signaling to Akt, Tumor Necrosis Factor Family Ligand Expression, and Apoptosis

  Jean-Marc Navenot, Nobutaka Fujii and Stephen C. Peiper

  Molecular Pharmacology May 2009, 75 (5) 1074-1083; DOI: https://doi.org/10.1124/mol.108.054270
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  Time-Resolved Photolabeling of the Nicotinic Acetylcholine Receptor by [³H]Azietomidate, an Open-State Inhibitor

  David C. Chiara, Filbert H. Hong, Enrique Arevalo, S. Shaukat Husain, Keith W. Miller, Stuart A. Forman and Jonathan B. Cohen

  Molecular Pharmacology May 2009, 75 (5) 1084-1095; DOI: https://doi.org/10.1124/mol.108.054353
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  Functional Characterization and In Silico Docking of Full and Partial GluK2 Kainate Receptor Agonists

  Anne-Marie L. Fay, Christopher R. Corbeil, Patricia Brown, Nicolas Moitessier and Derek Bowie

  Molecular Pharmacology May 2009, 75 (5) 1096-1107; DOI: https://doi.org/10.1124/mol.108.054254
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  Identification of Potential Pharmacological Targets by Analysis of the Comprehensive G Protein-Coupled Receptor Repertoire in the Four Cardiac Chambers

  Thomas Moore-Morris, Annie Varrault, Matteo E. Mangoni, Anne Le Digarcher, Vincent Negre, Christelle Dantec, Laurent Journot, Joel Nargeot and Brigitte Couette

  Molecular Pharmacology May 2009, 75 (5) 1108-1116; DOI: https://doi.org/10.1124/mol.108.054155
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  Mrp1 Localization and Function in Cardiac Mitochondria after Doxorubicin

  Paiboon Jungsuwadee, Ramaneeya Nithipongvanitch, Yumin Chen, Terry D. Oberley, D. Allan Butterfield, Daret K. St. Clair and Mary Vore

  Molecular Pharmacology May 2009, 75 (5) 1117-1126; DOI: https://doi.org/10.1124/mol.108.052209
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  Human Mitochondrial Thymidine Kinase Is Selectively Inhibited by 3′-Thiourea Derivatives of β-Thymidine: Identification of Residues Crucial for Both Inhibition and Catalytic Activity

  Jan Balzarini, Ineke Van Daele, Ana Negri, Nicola Solaroli, Anna Karlsson, Sandra Liekens, Federico Gago and Serge Van Calenbergh

  Molecular Pharmacology May 2009, 75 (5) 1127-1136; DOI: https://doi.org/10.1124/mol.108.053785
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  Nicotine Normalizes Intracellular Subunit Stoichiometry of Nicotinic Receptors Carrying Mutations Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy

  Cagdas D. Son, Fraser J. Moss, Bruce N. Cohen and Henry A. Lester

  Molecular Pharmacology May 2009, 75 (5) 1137-1148; DOI: https://doi.org/10.1124/mol.108.054494
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  Structural Determinants of Imidazoacridinones Facilitating Antitumor Activity Are Crucial for Substrate Recognition by ABCG2

  Eran E. Bram, Yamit Adar, Nufar Mesika, Michal Sabisz, Andrzej Skladanowski and Yehuda G. Assaraf

  Molecular Pharmacology May 2009, 75 (5) 1149-1159; DOI: https://doi.org/10.1124/mol.109.054791
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  Genetic Dissection of α₂-Adrenoceptor Functions in Adrenergic versus Nonadrenergic Cells

  Ralf Gilsbach, Christoph Röser, Nadine Beetz, Marc Brede, Kerstin Hadamek, Miriam Haubold, Jost Leemhuis, Melanie Philipp, Johanna Schneider, Michal Urbanski, Bela Szabo, David Weinshenker and Lutz Hein

  Molecular Pharmacology May 2009, 75 (5) 1160-1170; DOI: https://doi.org/10.1124/mol.109.054544
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  Dynamic Patterns of Histone Methylation Are Associated with Ontogenic Expression of the Cyp3a Genes during Mouse Liver Maturation

  Ye Li, Yue Cui, Steven N. Hart, Curtis D. Klaassen and Xiao-bo Zhong

  Molecular Pharmacology May 2009, 75 (5) 1171-1179; DOI: https://doi.org/10.1124/mol.108.052993
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  Induction of Overexpression of the 27- and 70-kDa Heat Shock Proteins by Bicyclol Attenuates Concanavalin A-Induced Liver Injury through Suppression of Nuclear Factor-κB in Mice

  Xiu-Qi Bao and Geng-Tao Liu

  Molecular Pharmacology May 2009, 75 (5) 1180-1188; DOI: https://doi.org/10.1124/mol.108.053280
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  NHERF1 Regulates Parathyroid Hormone Receptor Desensitization: Interference with β-Arrestin Binding

  Bin Wang, Yanmei Yang, Abdul B. Abou-Samra and Peter A. Friedman

  Molecular Pharmacology May 2009, 75 (5) 1189-1197; DOI: https://doi.org/10.1124/mol.108.054486
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  Prolyl Hydroxylase Inhibitors Depend on Extracellular Glucose and Hypoxia-Inducible Factor (HIF)-2α to Inhibit Cell Death Caused by Nerve Growth Factor (NGF) Deprivation: Evidence that HIF-2α Has a Role in NGF-Promoted Survival of Sympathetic Neurons

  David J. Lomb, Lynette A. Desouza, James L. Franklin and Robert S. Freeman

  Molecular Pharmacology May 2009, 75 (5) 1198-1209; DOI: https://doi.org/10.1124/mol.108.053157
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  Niflumic Acid Alters Gating of HCN2 Pacemaker Channels by Interaction with the Outer Region of S4 Voltage Sensing Domains

  Lan Cheng and Michael C. Sanguinetti

  Molecular Pharmacology May 2009, 75 (5) 1210-1221; DOI: https://doi.org/10.1124/mol.108.054437
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  Regulator of G Protein Signaling Protein Suppression of Gα_o Protein-Mediated α_2A Adrenergic Receptor Inhibition of Mouse Hippocampal CA3 Epileptiform Activity

  Brianna L. Goldenstein, Brian W. Nelson, Ke Xu, Elizabeth J. Luger, Jacquline A. Pribula, Jenna M. Wald, Lorraine A. O'Shea, David Weinshenker, Raelene A. Charbeneau, Xinyan Huang, Richard R. Neubig and Van A. Doze

  Molecular Pharmacology May 2009, 75 (5) 1222-1230; DOI: https://doi.org/10.1124/mol.108.054296
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  ABT-737 Synergizes with Chemotherapy to Kill Head and Neck Squamous Cell Carcinoma Cells via a Noxa-Mediated Pathway

  Rongxiu Li, Yan Zang, Changyou Li, Neil S. Patel, Jennifer R. Grandis and Daniel E. Johnson

  Molecular Pharmacology May 2009, 75 (5) 1231-1239; DOI: https://doi.org/10.1124/mol.108.052969
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  AMD3100 Is a CXCR7 Ligand with Allosteric Agonist Properties

  Irina Kalatskaya, Yamina A. Berchiche, Stéphanie Gravel, Brian J. Limberg, Jan S. Rosenbaum and Nikolaus Heveker

  Molecular Pharmacology May 2009, 75 (5) 1240-1247; DOI: https://doi.org/10.1124/mol.108.053389