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Research ArticleArticle

Prolyl Hydroxylase Inhibitors Depend on Extracellular Glucose and Hypoxia-Inducible Factor (HIF)-2α to Inhibit Cell Death Caused by Nerve Growth Factor (NGF) Deprivation: Evidence that HIF-2α Has a Role in NGF-Promoted Survival of Sympathetic Neurons

David J. Lomb, Lynette A. Desouza, James L. Franklin and Robert S. Freeman
Molecular Pharmacology May 2009, 75 (5) 1198-1209; DOI: https://doi.org/10.1124/mol.108.053157

Article Information

vol. 75 no. 5 1198-1209
DOI 
https://doi.org/10.1124/mol.108.053157
PubMed 
19204094
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received October 30, 2008
  • Accepted February 9, 2009
  • Published online April 23, 2009.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. David J. Lomb1,
  2. Lynette A. Desouza,
  3. James L. Franklin and
  4. Robert S. Freeman
  1. Department of Pharmacology and Physiology (D.J.L., R.S.F.) and the Interdepartmental Graduate Program in Neuroscience (L.A.D.), University of Rochester School of Medicine and Dentistry, Rochester, New York; and Department of Pharmaceutical and Biomedical Sciences, University of Georgia College of Pharmacy, Athens, Georgia (J.L.F.)
  1. Address correspondence to:
    Dr. Robert S. Freeman, Department of Pharmacology and Physiology, University of Rochester School of Medicine, 601 Elmwood Avenue, Rochester, NY 14642. E-mail: robert_freeman{at}urmc.rochester.edu
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Research ArticleArticle

Prolyl Hydroxylase Inhibitors Depend on Extracellular Glucose and Hypoxia-Inducible Factor (HIF)-2α to Inhibit Cell Death Caused by Nerve Growth Factor (NGF) Deprivation: Evidence that HIF-2α Has a Role in NGF-Promoted Survival of Sympathetic Neurons

David J. Lomb, Lynette A. Desouza, James L. Franklin and Robert S. Freeman
Molecular Pharmacology May 1, 2009, 75 (5) 1198-1209; DOI: https://doi.org/10.1124/mol.108.053157
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