Table of Contents

Articles

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  Mutational and In Silico Analyses for Antidepressant Block of Astroglial Inward-Rectifier Kir4.1 Channel

  Kazuharu Furutani, Yukihiro Ohno, Atsushi Inanobe, Hiroshi Hibino and Yoshihisa Kurachi

  Molecular Pharmacology June 2009, 75 (6) 1287-1295; DOI: https://doi.org/10.1124/mol.108.052936
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  Instability of a Class A G Protein-Coupled Receptor Oligomer Interface

  Jacqueline M. Fonseca and Nevin A. Lambert

  Molecular Pharmacology June 2009, 75 (6) 1296-1299; DOI: https://doi.org/10.1124/mol.108.053876
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  Activation of Rho and Rho-Associated Kinase by GPR54 and KiSS1 Metastasis Suppressor Gene Product Induces Changes of Cell Morphology and Contributes to Apoptosis

  Jean-Marc Navenot, Nobutaka Fujii and Stephen C. Peiper

  Molecular Pharmacology June 2009, 75 (6) 1300-1306; DOI: https://doi.org/10.1124/mol.109.055095
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  μ-Opioid Receptor Cell Surface Expression Is Regulated by Its Direct Interaction with Ribophorin I

  Xin Ge, Horace H. Loh and Ping-Yee Law

  Molecular Pharmacology June 2009, 75 (6) 1307-1316; DOI: https://doi.org/10.1124/mol.108.054064
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  Met909 Plays a Key Role in the Activation of the Progesterone Receptor and Also in the High Potency of 13-Ethyl Progestins

  Isabelle Petit-Topin, Nathalie Turque, Jérôme Fagart, Michel Fay, André Ulmann, Erin Gainer and Marie-Edith Rafestin-Oblin

  Molecular Pharmacology June 2009, 75 (6) 1317-1324; DOI: https://doi.org/10.1124/mol.108.054312
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  Elucidation of Binding Sites of Dual Antagonists in the Human Chemokine Receptors CCR2 and CCR5

  Spencer E. Hall, Allen Mao, Vicky Nicolaidou, Mattea Finelli, Emma L. Wise, Belinda Nedjai, Julie Kanjanapangka, Paymann Harirchian, Deborah Chen, Victor Selchau, Sofia Ribeiro, Sabine Schyler, James E. Pease, Richard Horuk and Nagarajan Vaidehi

  Molecular Pharmacology June 2009, 75 (6) 1325-1336; DOI: https://doi.org/10.1124/mol.108.053470
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  CYP4F2 Is a Vitamin K₁ Oxidase: An Explanation for Altered Warfarin Dose in Carriers of the V433M Variant

  Matthew G. McDonald, Mark J. Rieder, Mariko Nakano, Clara K. Hsia and Allan E. Rettie

  Molecular Pharmacology June 2009, 75 (6) 1337-1346; DOI: https://doi.org/10.1124/mol.109.054833
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  An Ivermectin-Sensitive Glutamate-Gated Chloride Channel from the Parasitic Nematode Haemonchus contortus

  Samantha McCavera, Adrian T. Rogers, Darran M. Yates, Debra J. Woods and Adrian J. Wolstenholme

  Molecular Pharmacology June 2009, 75 (6) 1347-1355; DOI: https://doi.org/10.1124/mol.108.053363
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  Bifunctional DNA Alkylator 1,3-Bis(2-chloroethyl)-1-nitrosourea Activates the ATR-Chk1 Pathway Independently of the Mismatch Repair Pathway

  B. Cui, S. P. Johnson, N. Bullock, F. Ali-Osman, D. D. Bigner and H. S. Friedman

  Molecular Pharmacology June 2009, 75 (6) 1356-1363; DOI: https://doi.org/10.1124/mol.108.053124
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  Enhancement of Doxorubicin Cytotoxicity on Human Esophageal Squamous Cell Carcinoma Cells by Indomethacin and 4-[5-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (SC236) via Inhibiting P-Glycoprotein Activity

  Le Yu, William Ka Kei Wu, Zhi Jie Li, Qi Cai Liu, Hai Tao Li, Ya Chun Wu and Chi Hin Cho

  Molecular Pharmacology June 2009, 75 (6) 1364-1373; DOI: https://doi.org/10.1124/mol.108.053546
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  MicroRNA-328 Negatively Regulates the Expression of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Cancer Cells

  Yu-Zhuo Pan, Marilyn E. Morris and Ai-Ming Yu

  Molecular Pharmacology June 2009, 75 (6) 1374-1379; DOI: https://doi.org/10.1124/mol.108.054163
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  Evidence for Distinct Antagonist-Revealed Functional States of 5-Hydroxytryptamine_2A Receptor Homodimers

  José Brea, Marián Castro, Jesús Giraldo, Juan F. López-Giménez, Juan Fernando Padín, Fátima Quintián, Maria Isabel Cadavid, Maria Teresa Vilaró, Guadalupe Mengod, Kelly A. Berg, William P. Clarke, Jean-Pierre Vilardaga, Graeme Milligan and Maria Isabel Loza

  Molecular Pharmacology June 2009, 75 (6) 1380-1391; DOI: https://doi.org/10.1124/mol.108.054395
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  Regulation of Human Vitamin D₃ 25-Hydroxylases in Dermal Fibroblasts and Prostate Cancer LNCaP Cells

  Maria Ellfolk, Maria Norlin, Katarina Gyllensten and Kjell Wikvall

  Molecular Pharmacology June 2009, 75 (6) 1392-1399; DOI: https://doi.org/10.1124/mol.108.053660
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  Activation and Modulation of Concatemeric GABA-A Receptors Expressed in Human Embryonic Kidney Cells

  Gustav Akk, Ping Li, John Bracamontes and Joe Henry Steinbach

  Molecular Pharmacology June 2009, 75 (6) 1400-1411; DOI: https://doi.org/10.1124/mol.108.054510
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  Ligand Selectivity and Gene Regulation by the Human Aryl Hydrocarbon Receptor in Transgenic Mice

  Colin A. Flaveny, Iain A. Murray, Chris R. Chiaro and Gary H. Perdew

  Molecular Pharmacology June 2009, 75 (6) 1412-1420; DOI: https://doi.org/10.1124/mol.109.054825
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  Statin-Induced Liver Injury Involves Cross-Talk between Cholesterol and Selenoprotein Biosynthetic Pathways

  Andrea Kromer and Bernd Moosmann

  Molecular Pharmacology June 2009, 75 (6) 1421-1429; DOI: https://doi.org/10.1124/mol.108.053678
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  A Small-Molecule Modulator Interacts Directly with ΔPhe508-CFTR to Modify Its ATPase Activity and Conformational Stability

  Leigh Wellhauser, Patrick Kim Chiaw, Stan Pasyk, Canhui Li, Mohabir Ramjeesingh and Christine E. Bear

  Molecular Pharmacology June 2009, 75 (6) 1430-1438; DOI: https://doi.org/10.1124/mol.109.055608