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Research ArticleArticle

Inhibition of Aquaporin-1 and Aquaporin-4 Water Permeability by a Derivative of the Loop Diuretic Bumetanide Acting at an Internal Pore-Occluding Binding Site

Elton Migliati, Nathalie Meurice, Pascale DuBois, Jennifer S. Fang, Suma Somasekharan, Elizabeth Beckett, Gary Flynn and Andrea J. Yool
Molecular Pharmacology July 2009, 76 (1) 105-112; DOI: https://doi.org/10.1124/mol.108.053744

Article Information

vol. 76 no. 1 105-112
DOI 
https://doi.org/10.1124/mol.108.053744
PubMed 
19403703
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Accepted April 23, 2009
  • Received November 26, 2008
  • Published online June 24, 2009.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Elton Migliati,
  2. Nathalie Meurice,
  3. Pascale DuBois,
  4. Jennifer S. Fang,
  5. Suma Somasekharan,
  6. Elizabeth Beckett,
  7. Gary Flynn and
  8. Andrea J. Yool
  1. Discipline of Physiology, School of Molecular and Biomedical Science, University of Adelaide, Adelaide, Australia (A.J.Y., E.B., P.D.); Physiological Sciences Program, University of Arizona, Tucson, Arizona (A.J.Y., E.M., J.S.F.); College of Pharmacy & BIO5 Institute, University of Arizona, Tucson, Arizona (N.M., G.F.); Chemogenomics Laboratory, Translational Genomics Research Institute (TGen), Phoenix, Arizona, and FRS-FNRS, Laboratoire de Physico-Chimie Informatique, University of Namur, Namur, Belgium (N.M.); and Department of Cellular & Molecular Physiology, Yale University, New Haven, Connecticut (S.S.)
  1. Address correspondence to:
    Dr. Andrea Yool, Discipline of Physiology, School of Molecular and Biomedical Science, Med School South Level 4 Frome Road, University of Adelaide, Adelaide SA 5005, Australia. E-mail: andrea.yool{at}adelaide.edu.au
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Research ArticleArticle

Inhibition of Aquaporin-1 and Aquaporin-4 Water Permeability by a Derivative of the Loop Diuretic Bumetanide Acting at an Internal Pore-Occluding Binding Site

Elton Migliati, Nathalie Meurice, Pascale DuBois, Jennifer S. Fang, Suma Somasekharan, Elizabeth Beckett, Gary Flynn and Andrea J. Yool
Molecular Pharmacology July 1, 2009, 76 (1) 105-112; DOI: https://doi.org/10.1124/mol.108.053744
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