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Molecular Pharmacology

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Table of Contents

August 01, 2009; Volume 76,Issue 2

CENTENNIAL PERSPECTIVE

  • You have access
    Sex Differences in the Expression of Hepatic Drug Metabolizing Enzymes
    David J. Waxman and Minita G. Holloway
    Molecular Pharmacology August 2009, 76 (2) 215-228; DOI: https://doi.org/10.1124/mol.109.056705

MINIREVIEWS

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    Trace Amine-Associated Receptors as Emerging Therapeutic Targets
    Tatyana D. Sotnikova, Marc G. Caron and Raul R. Gainetdinov
    Molecular Pharmacology August 2009, 76 (2) 229-235; DOI: https://doi.org/10.1124/mol.109.055970
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    Diphosphoinositol Polyphosphates: Metabolic Messengers?
    Stephen B. Shears
    Molecular Pharmacology August 2009, 76 (2) 236-252; DOI: https://doi.org/10.1124/mol.109.055897

Articles

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    An Allosteric Modulator of α7 Nicotinic Receptors, N-(5-Chloro-2,4-dimethoxyphenyl)-N′-(5-methyl-3-isoxazolyl)-urea (PNU-120596), Causes Conformational Changes in the Extracellular Ligand Binding Domain Similar to Those Caused by Acetylcholine
    Sean C. Barron, James T. McLaughlin, Jennifer A. See, Vanessa L. Richards and Robert L. Rosenberg
    Molecular Pharmacology August 2009, 76 (2) 253-263; DOI: https://doi.org/10.1124/mol.109.056226
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    Functional Importance of a Structurally Distinct Homodimeric Complex of the Family B G Protein-Coupled Secretin Receptor
    Fan Gao, Kaleeckal G. Harikumar, Maoqing Dong, Polo C.-H. Lam, Patrick M. Sexton, Arthur Christopoulos, Andrew Bordner, Ruben Abagyan and Laurence J. Miller
    Molecular Pharmacology August 2009, 76 (2) 264-274; DOI: https://doi.org/10.1124/mol.109.055756
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    Five Amino Acids in the Innermost Cavity of the Substrate Binding Cleft of Organic Cation Transporter 1 Interact with Extracellular and Intracellular Corticosterone
    Christopher Volk, Valentin Gorboulev, Alexander Kotzsch, Thomas D. Müller and Hermann Koepsell
    Molecular Pharmacology August 2009, 76 (2) 275-289; DOI: https://doi.org/10.1124/mol.109.054783
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    Antitumor Effects of Dehydroxymethylepoxyquinomicin, a Novel Nuclear Factor-κB Inhibitor, in Human Liver Cancer Cells Are Mediated through a Reactive Oxygen Species-Dependent Mechanism
    Nadia Lampiasi, Antonina Azzolina, Natale D'Alessandro, Kazuo Umezawa, James A. McCubrey, Giuseppe Montalto and Melchiorre Cervello
    Molecular Pharmacology August 2009, 76 (2) 290-300; DOI: https://doi.org/10.1124/mol.109.055418
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    Irreversible Platelet Activation Requires Protease-Activated Receptor 1-Mediated Signaling to Phosphatidylinositol Phosphates
    Michael Holinstat, Anita M. Preininger, Stephen B. Milne, W. James Hudson, H. Alex Brown and Heidi E. Hamm
    Molecular Pharmacology August 2009, 76 (2) 301-313; DOI: https://doi.org/10.1124/mol.109.056622
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    α1-Adrenergic Receptors Regulate Neurogenesis and Gliogenesis
    Manveen K. Gupta, Robert S. Papay, Chris W. D. Jurgens, Robert J. Gaivin, Ting Shi, Van A. Doze and Dianne M. Perez
    Molecular Pharmacology August 2009, 76 (2) 314-326; DOI: https://doi.org/10.1124/mol.109.057307
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    BCL-2 Family Inhibitors Enhance Histone Deacetylase Inhibitor and Sorafenib Lethality via Autophagy and Overcome Blockade of the Extrinsic Pathway to Facilitate Killing
    Aditi Pandya Martin, Margaret A. Park, Clint Mitchell, Teneille Walker, Mohamed Rahmani, Andrew Thorburn, Dieter Häussinger, Roland Reinehr, Steven Grant and Paul Dent
    Molecular Pharmacology August 2009, 76 (2) 327-341; DOI: https://doi.org/10.1124/mol.109.056309
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    Sorafenib and Vorinostat Kill Colon Cancer Cells by CD95-Dependent and -Independent Mechanisms
    Teneille Walker, Clint Mitchell, Margaret A. Park, Adly Yacoub, Martin Graf, Mohamed Rahmani, Peter J. Houghton, Christina Voelkel-Johnson, Steven Grant and Paul Dent
    Molecular Pharmacology August 2009, 76 (2) 342-355; DOI: https://doi.org/10.1124/mol.109.056523
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    A Novel Selective Muscarinic Acetylcholine Receptor Subtype 1 Antagonist Reduces Seizures without Impairing Hippocampus-Dependent Learning
    Douglas J. Sheffler, Richard Williams, Thomas M. Bridges, Zixiu Xiang, Alexander S. Kane, Nellie E. Byun, Satyawan Jadhav, Mathew M. Mock, Fang Zheng, L. Michelle Lewis, Carrie K. Jones, Colleen M. Niswender, Charles D. Weaver, Craig W. Lindsley and P. Jeffrey Conn
    Molecular Pharmacology August 2009, 76 (2) 356-368; DOI: https://doi.org/10.1124/mol.109.056531
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    Augmentation of Fear Extinction by Infusion of Glycine Transporter Blockers into the Amygdala
    Sheng-Chun Mao, Hui-Ching Lin and Po-Wu Gean
    Molecular Pharmacology August 2009, 76 (2) 369-378; DOI: https://doi.org/10.1124/mol.108.053728
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    Activation of mGlu2/3 Metabotropic Glutamate Receptors Negatively Regulates the Stimulation of Inositol Phospholipid Hydrolysis Mediated by 5-Hydroxytryptamine2A Serotonin Receptors in the Frontal Cortex of Living Mice
    G. Molinaro, A. Traficante, B. Riozzi, L. Di Menna, M. Curto, S. Pallottino, F. Nicoletti, V. Bruno and G. Battaglia
    Molecular Pharmacology August 2009, 76 (2) 379-387; DOI: https://doi.org/10.1124/mol.109.056580
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    Cytosolic Aryl Sulfotransferase 4A1 Interacts with the Peptidyl Prolyl Cis-Trans Isomerase Pin1
    Deanne J. Mitchell and Rodney F. Minchin
    Molecular Pharmacology August 2009, 76 (2) 388-395; DOI: https://doi.org/10.1124/mol.109.055442
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    Controls of Tonic and Phasic Dopamine Transmission in the Dorsal and Ventral Striatum
    Lifen Zhang, William M. Doyon, Jeremy J. Clark, Paul E. M. Phillips and John A. Dani
    Molecular Pharmacology August 2009, 76 (2) 396-404; DOI: https://doi.org/10.1124/mol.109.056317
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    Comparative Study of Inhibition at Multiple Stages of Amyloid-β Self-Assembly Provides Mechanistic Insight
    Timothy J. Davis, Deborah D. Soto-Ortega, Joseph A. Kotarek, Francisco J. Gonzalez-Velasquez, Krishnamoothy Sivakumar, Laying Wu, Qian Wang and Melissa A. Moss
    Molecular Pharmacology August 2009, 76 (2) 405-413; DOI: https://doi.org/10.1124/mol.109.055301
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    Peroxisome Proliferator-Activated Receptor (PPAR)-γ Positively Controls and PPARα Negatively Controls Cyclooxygenase-2 Expression in Rat Brain Astrocytes through a Convergence on PPARβ/δ via Mutual Control of PPAR Expression Levels
    Stepan Aleshin, Sevil Grabeklis, Theodor Hanck, Marina Sergeeva and Georg Reiser
    Molecular Pharmacology August 2009, 76 (2) 414-424; DOI: https://doi.org/10.1124/mol.109.056010
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    Estrogen Receptor α, Fos-Related Antigen-2, and c-Jun Coordinately Regulate Human UDP Glucuronosyltransferase 2B15 and 2B17 Expression in Response to 17β-Estradiol in MCF-7 Cells
    Dong Gui Hu and Peter I. Mackenzie
    Molecular Pharmacology August 2009, 76 (2) 425-439; DOI: https://doi.org/10.1124/mol.109.057380
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    Docking of 1,4-Benzodiazepines in the α1/γ2 GABAA Receptor Modulator Site
    D. Berezhnoy, T. T. Gibbs and D. H. Farb
    Molecular Pharmacology August 2009, 76 (2) 440-450; DOI: https://doi.org/10.1124/mol.109.054650

Errata

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    Correction to “Mutational and in Silico Analyses for Antidepressant Block of Astroglial Inward-Rectifier Kir4.1 Channel”
    Molecular Pharmacology August 2009, 76 (2) 451; DOI: https://doi.org/10.1124/mol.76.2.451
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    Correction to “Knock-In Mouse Lines Expressing either Mitochondrial or Microsomal CYP1A1: Differing Responses to Dietary Benzo[a]pyrene as Proof of Principle”
    Molecular Pharmacology August 2009, 76 (2) 452; DOI: https://doi.org/10.1124/mol.76.2.452
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In this issue

Molecular Pharmacology: 76 (2)
Molecular Pharmacology
Vol. 76, Issue 2
1 Aug 2009
  • Table of Contents
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  • About the Cover
  • Index by author
  • Back Matter (PDF)
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  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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