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Molecular Pharmacology

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Table of Contents

September 01, 2009; Volume 76,Issue 3

MINIREVIEWS

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    Molecular Pharmacology of Promiscuous Seven Transmembrane Receptors Sensing Organic Nutrients
    Petrine Wellendorph, Lars Dan Johansen and Hans Bräuner-Osborne
    Molecular Pharmacology September 2009, 76 (3) 453-465; DOI: https://doi.org/10.1124/mol.109.055244
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    Mechanisms of Pharmacogenomic Effects of Genetic Variation within the Cardiac Adrenergic Network in Heart Failure
    Gerald W. Dorn and Stephen B. Liggett
    Molecular Pharmacology September 2009, 76 (3) 466-480; DOI: https://doi.org/10.1124/mol.109.056572
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    Toward a Systems Level Understanding of Organic Anion and Other Multispecific Drug Transporters: A Remote Sensing and Signaling Hypothesis
    Sun-Young Ahn and Sanjay K. Nigam
    Molecular Pharmacology September 2009, 76 (3) 481-490; DOI: https://doi.org/10.1124/mol.109.056564

Articles

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    Stabilizers of the Max Homodimer Identified in Virtual Ligand Screening Inhibit Myc Function
    Hao Jiang, Kristen E. Bower, Albert E. Beuscher, Bin Zhou, Andrey A. Bobkov, Arthur J. Olson and Peter K. Vogt
    Molecular Pharmacology September 2009, 76 (3) 491-502; DOI: https://doi.org/10.1124/mol.109.054858
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    RETRACTION: Hepatic CYP3A Suppression by High Concentrations of Proteasomal Inhibitors: A Consequence of Endoplasmic Reticulum (ER) Stress Induction, Activation of RNA-Dependent Protein Kinase-Like ER-Bound Eukaryotic Initiation Factor 2α (eIF2α)-Kinase (PERK) and General Control Nonderepressible-2 eIF2α Kinase (GCN2), and Global Translational Shutoff
    Poulomi Acharya, Juan C. Engel and Maria Almira Correia
    Molecular Pharmacology September 2009, 76 (3) 503-515; DOI: https://doi.org/10.1124/mol.109.056002
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    15-oxo-Eicosatetraenoic Acid, a Metabolite of Macrophage 15-Hydroxyprostaglandin Dehydrogenase That Inhibits Endothelial Cell Proliferation
    Cong Wei, Peijuan Zhu, Sumit J. Shah and Ian A. Blair
    Molecular Pharmacology September 2009, 76 (3) 516-525; DOI: https://doi.org/10.1124/mol.109.057489
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    Up-Regulation of AGS3 during Morphine Withdrawal Promotes cAMP Superactivation via Adenylyl Cyclase 5 and 7 in Rat Nucleus Accumbens/Striatal Neurons
    Peidong Fan, Zhan Jiang, Ivan Diamond and Lina Yao
    Molecular Pharmacology September 2009, 76 (3) 526-533; DOI: https://doi.org/10.1124/mol.109.057802
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    A Nondesensitizing Kainate Receptor Point Mutant
    Naushaba Nayeem, Yihong Zhang, Devin K. Schweppe, Dean R. Madden and Tim Green
    Molecular Pharmacology September 2009, 76 (3) 534-542; DOI: https://doi.org/10.1124/mol.109.056598
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    Exploring the Mechanism of Agonist Efficacy: A Relationship between Efficacy and Agonist Dissociation Rate at the Muscarinic M3 Receptor
    David A. Sykes, Mark R. Dowling and Steven J. Charlton
    Molecular Pharmacology September 2009, 76 (3) 543-551; DOI: https://doi.org/10.1124/mol.108.054452
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    Human 5-HT7 Receptor-Induced Inactivation of Forskolin-Stimulated Adenylate Cyclase by Risperidone, 9-OH-Risperidone and Other “Inactivating Antagonists”
    Nicole Toohey, Michael T. Klein, Jessica Knight, Carol Smith and Milt Teitler
    Molecular Pharmacology September 2009, 76 (3) 552-559; DOI: https://doi.org/10.1124/mol.109.056283
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    The Na+/Ca2+ Exchange Inhibitor 2-(2-(4-(4-Nitrobenzyloxy)phenyl)ethyl)isothiourea Methanesulfonate (KB-R7943) Also Blocks Ryanodine Receptors Type 1 (RyR1) and Type 2 (RyR2) Channels
    Genaro Barrientos, Diptiman D. Bose, Wei Feng, Isela Padilla and Isaac N. Pessah
    Molecular Pharmacology September 2009, 76 (3) 560-568; DOI: https://doi.org/10.1124/mol.109.057265
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    Selective Activation of the SK1 Subtype of Human Small-Conductance Ca2+-Activated K+ Channels by 4-(2-Methoxyphenylcarbamoyloxymethyl)-piperidine-1-carboxylic Acid tert-Butyl Ester (GW542573X) Is Dependent on Serine 293 in the S5 Segment
    Charlotte Hougaard, Marianne L. Jensen, Tim J. Dale, David D. Miller, David J. Davies, Birgitte L. Eriksen, Dorte Strøbæk, Derek J. Trezise and Palle Christophersen
    Molecular Pharmacology September 2009, 76 (3) 569-578; DOI: https://doi.org/10.1124/mol.109.056663
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    Benzene Metabolite Hydroquinone Up-Regulates Chondromodulin-I and Inhibits Tube Formation in Human Bone Marrow Endothelial Cells
    Hongfei Zhou, Jadwiga K. Kepa, David Siegel, Shigenori Miura, Yuji Hiraki and David Ross
    Molecular Pharmacology September 2009, 76 (3) 579-587; DOI: https://doi.org/10.1124/mol.109.057323
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    Docosahexaenoic Acid Inhibits Superoxide Dismutase 1 Gene Transcription in Human Cancer Cells: The Involvement of Peroxisome Proliferator-Activated Receptor α and Hypoxia-Inducible Factor-2α Signaling
    Erin R. Tuller, Charles T. Beavers, Jessica R. Lou, Michael A. Ihnat, Doris M. Benbrook and Wei-Qun Ding
    Molecular Pharmacology September 2009, 76 (3) 588-595; DOI: https://doi.org/10.1124/mol.109.057430
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    Autophagy-Mediated Insulin Receptor Down-Regulation Contributes to Endoplasmic Reticulum Stress-Induced Insulin Resistance
    Lijun Zhou, Jingjing Zhang, Qichen Fang, Meilian Liu, Xianling Liu, Weiping Jia, Lily Q. Dong and Feng Liu
    Molecular Pharmacology September 2009, 76 (3) 596-603; DOI: https://doi.org/10.1124/mol.109.057067
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    The Aldo-Keto Reductase Akr1b7 Gene Is a Common Transcriptional Target of Xenobiotic Receptors Pregnane X Receptor and Constitutive Androstane Receptor
    Ming-Jie Liu, Yuki Takahashi, Taira Wada, Jinhan He, Jie Gao, Yanan Tian, Song Li and Wen Xie
    Molecular Pharmacology September 2009, 76 (3) 604-611; DOI: https://doi.org/10.1124/mol.109.057455
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    Adenovirus-Transduced Human Butyrylcholinesterase in Mouse Blood Functions as a Bioscavenger of Chemical Warfare Nerve Agents
    Nageswararao Chilukuri, Ellen G. Duysen, Kalpana Parikh, Robert diTargiani, Bhupendra P. Doctor, Oksana Lockridge and Ashima Saxena
    Molecular Pharmacology September 2009, 76 (3) 612-617; DOI: https://doi.org/10.1124/mol.109.055665
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    Biochemical and Electrophysiological Characterization of Almorexant, a Dual Orexin 1 Receptor (OX1)/Orexin 2 Receptor (OX2) Antagonist: Comparison with Selective OX1 and OX2 Antagonists
    Pari Malherbe, Edilio Borroni, Emmanuel Pinard, Joseph G. Wettstein and Frédéric Knoflach
    Molecular Pharmacology September 2009, 76 (3) 618-631; DOI: https://doi.org/10.1124/mol.109.055152
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    Etoposide Induces Protein Kinase Cδ- and Caspase-3-Dependent Apoptosis in Neuroblastoma Cancer Cells
    Travis W. Day, Ching-Huang Wu and Ahmad R. Safa
    Molecular Pharmacology September 2009, 76 (3) 632-640; DOI: https://doi.org/10.1124/mol.109.054999
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    Inverse Effects on Gating and Modulation Caused by a Mutation in the M2-M3 Linker of the GABAA Receptor γ Subunit
    Sean M. O'Shea, Carrie A. Williams and Andrew Jenkins
    Molecular Pharmacology September 2009, 76 (3) 641-651; DOI: https://doi.org/10.1124/mol.109.055111
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    Selective Inhibition of Acetylcholine-Evoked Responses of α7 Neuronal Nicotinic Acetylcholine Receptors by Novel tris- and tetrakis-Azaaromatic Quaternary Ammonium Antagonists
    Gretchen Y. López-Hernández, Jeffrey S. Thinschmidt, Guangrong Zheng, Zhenfa Zhang, Peter A. Crooks, Linda P. Dwoskin and Roger L. Papke
    Molecular Pharmacology September 2009, 76 (3) 652-666; DOI: https://doi.org/10.1124/mol.109.056176
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    Dual Mechanisms of sHA 14-1 in Inducing Cell Death through Endoplasmic Reticulum and Mitochondria
    David Hermanson, Sadiya N. Addo, Anna A. Bajer, Jonathan S. Marchant, Sonia Goutam Kumar Das, Balasubramanian Srinivasan, Fawaz Al-Mousa, Francesco Michelangeli, David D. Thomas, Tucker W. LeBien and Chengguo Xing
    Molecular Pharmacology September 2009, 76 (3) 667-678; DOI: https://doi.org/10.1124/mol.109.055830
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In this issue

Molecular Pharmacology: 76 (3)
Molecular Pharmacology
Vol. 76, Issue 3
1 Sep 2009
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  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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