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Molecular Pharmacology

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Reactive Oxygen Species-Dependent Activation of Bax and Poly(ADP-ribose) Polymerase-1 Is Required for Mitochondrial Cell Death Induced by Triterpenoid Pristimerin in Human Cervical Cancer Cells

Joo-Yun Byun, Min-Jung Kim, Da-Young Eum, Chang-Hwan Yoon, Woo-Duck Seo, Ki Hun Park, Jin-Won Hyun, Yun-Sil Lee, Jae-Seong Lee, Moon-Young Yoon and Su-Jae Lee
Molecular Pharmacology October 2009, 76 (4) 734-744; DOI: https://doi.org/10.1124/mol.109.056259
Joo-Yun Byun
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Min-Jung Kim
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Da-Young Eum
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Ki Hun Park
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Yun-Sil Lee
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Article Information

vol. 76 no. 4 734-744
DOI 
https://doi.org/10.1124/mol.109.056259
PubMed 
19574249

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received March 16, 2009
  • Accepted July 2, 2009
  • Published online September 21, 2009.

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  • Earlier version (July 2, 2009 - 06:34).
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© 2009 The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Joo-Yun Byun,
  2. Min-Jung Kim,
  3. Da-Young Eum,
  4. Chang-Hwan Yoon,
  5. Woo-Duck Seo,
  6. Ki Hun Park,
  7. Jin-Won Hyun,
  8. Yun-Sil Lee,
  9. Jae-Seong Lee,
  10. Moon-Young Yoon and
  11. Su-Jae Lee
  1. Department of Chemistry, Hanyang University, Seoul, Korea (J.B., M.K., D.E., C.Y., J.L., M.Y., S.L.); Department of Functional Crop, NICS, RDA, Milyang, Korea (W.S.); Division of Applied Life Science, Gyeongsang National University, Jinju, Korea (K.P.); College of Medicine and Applied Radiological Science Research Institute, Cheju National University, Jeju-si, Korea (J.H.); and Division of Radiation Effect, Korea Institute of Radiological and Medical Sciences, Seoul, Korea (Y.L.)
  1. Address correspondence to:
    Dr. Su-Jae Lee, Laboratory of Molecular Biochemistry, Department of Chemistry, Hanyang University, 17 Haengdang-Dong, Seongdong-Ku, Seoul 133-791, Korea. E-mail: sj0420{at}hanyang.ac.kr
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Molecular Pharmacology: 76 (4)
Molecular Pharmacology
Vol. 76, Issue 4
October 2009
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Reactive Oxygen Species-Dependent Activation of Bax and Poly(ADP-ribose) Polymerase-1 Is Required for Mitochondrial Cell Death Induced by Triterpenoid Pristimerin in Human Cervical Cancer Cells

Joo-Yun Byun, Min-Jung Kim, Da-Young Eum, Chang-Hwan Yoon, Woo-Duck Seo, Ki Hun Park, Jin-Won Hyun, Yun-Sil Lee, Jae-Seong Lee, Moon-Young Yoon and Su-Jae Lee
Molecular Pharmacology October 1, 2009, 76 (4) 734-744; DOI: https://doi.org/10.1124/mol.109.056259

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Reactive Oxygen Species-Dependent Activation of Bax and Poly(ADP-ribose) Polymerase-1 Is Required for Mitochondrial Cell Death Induced by Triterpenoid Pristimerin in Human Cervical Cancer Cells

Joo-Yun Byun, Min-Jung Kim, Da-Young Eum, Chang-Hwan Yoon, Woo-Duck Seo, Ki Hun Park, Jin-Won Hyun, Yun-Sil Lee, Jae-Seong Lee, Moon-Young Yoon and Su-Jae Lee
Molecular Pharmacology October 1, 2009, 76 (4) 734-744; DOI: https://doi.org/10.1124/mol.109.056259
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