Table of Contents

Articles

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  Identification of Compounds that Correlate with ABCG2 Transporter Function in the National Cancer Institute Anticancer Drug Screen

  John F. Deeken, Robert W. Robey, Suneet Shukla, Kenneth Steadman, Arup R. Chakraborty, Balasubramanian Poonkuzhali, Erin G. Schuetz, Susan Holbeck, Suresh V. Ambudkar and Susan E. Bates

  Molecular Pharmacology November 2009, 76 (5) 946-956; DOI: https://doi.org/10.1124/mol.109.056192
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  Targeting of the Akt-Nuclear Factor-κB Signaling Network by [1-(4-Chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a Novel Indole-3-Carbinol Derivative, in a Mouse Model of Hepatocellular Carcinoma

  Hany A. Omar, Aaron M. Sargeant, Jing-Ru Weng, Dasheng Wang, Samuel K. Kulp, Tushar Patel and Ching-Shih Chen

  Molecular Pharmacology November 2009, 76 (5) 957-968; DOI: https://doi.org/10.1124/mol.109.058180
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  Potential Use of Cetrimonium Bromide as an Apoptosis-Promoting Anticancer Agent for Head and Neck Cancer

  Emma Ito, Kenneth W. Yip, David Katz, Sonali B. Fonseca, David W. Hedley, Sue Chow, G. Wei Xu, Tabitha E. Wood, Carlo Bastianutto, Aaron D. Schimmer, Shana O. Kelley and Fei-Fei Liu

  Molecular Pharmacology November 2009, 76 (5) 969-983; DOI: https://doi.org/10.1124/mol.109.055277
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  Plasma Membrane Nucleolin Is a Receptor for the Anticancer Aptamer AS1411 in MV4-11 Leukemia Cells

  Sridharan Soundararajan, Li Wang, Vijayalakshmi Sridharan, Weiwei Chen, Nigel Courtenay-Luck, David Jones, Eleanor K. Spicer and Daniel J. Fernandes

  Molecular Pharmacology November 2009, 76 (5) 984-991; DOI: https://doi.org/10.1124/mol.109.055947
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  Altered G-Protein Coupling in an mGluR6 Point Mutant Associated with Congenital Stationary Night Blindness

  Donald Beqollari, Matthew J. Betzenhauser and Paul J. Kammermeier

  Molecular Pharmacology November 2009, 76 (5) 992-997; DOI: https://doi.org/10.1124/mol.109.058628
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  Bid and Calpains Cooperate to Trigger Oxaliplatin-Induced Apoptosis of Cervical Carcinoma HeLa Cells

  Sergio Anguissola, Barbara Köhler, Robert O'Byrne, Heiko Düssmann, Mary D. Cannon, Frank E. Murray, Caoimhin G. Concannon, Markus Rehm, Donat Kögel and Jochen H. M. Prehn

  Molecular Pharmacology November 2009, 76 (5) 998-1010; DOI: https://doi.org/10.1124/mol.109.058156
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  tert-Butylphenylacetylene Is a Potent Mechanism-Based Inactivator of Cytochrome P450 2B4: Inhibition of Cytochrome P450 Catalysis by Steric Hindrance

  Haoming Zhang, Hsia-lien Lin, Vyvyca J. Walker, Djemel Hamdane and Paul F. Hollenberg

  Molecular Pharmacology November 2009, 76 (5) 1011-1018; DOI: https://doi.org/10.1124/mol.109.059808
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  Interactions of Histamine H₁-Receptor Agonists and Antagonists with the Human Histamine H₄-Receptor

  Karl-Friedrich Deml, Silke Beermann, Detlef Neumann, Andrea Strasser and Roland Seifert

  Molecular Pharmacology November 2009, 76 (5) 1019-1030; DOI: https://doi.org/10.1124/mol.109.058651
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  Functional Characterization of Human Cytochrome P450 2S1 Using a Synthetic Gene-Expressed Protein in Escherichia coli

  Peter H. Bui and Oliver Hankinson

  Molecular Pharmacology November 2009, 76 (5) 1031-1043; DOI: https://doi.org/10.1124/mol.109.057752
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  Fatty Acid Hydroperoxides Support Cytochrome P450 2S1-Mediated Bioactivation of Benzo[a]pyrene-7,8-dihydrodiol

  Peter H. Bui, Erin L. Hsu and Oliver Hankinson

  Molecular Pharmacology November 2009, 76 (5) 1044-1052; DOI: https://doi.org/10.1124/mol.109.057760
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  Differential Effects of Selective Cyclooxygenase-2 Inhibitors on Vascular Smooth Muscle Ion Channels May Account for Differences in Cardiovascular Risk Profiles

  Lioubov I. Brueggemann, Alexander R. Mackie, Bharath K. Mani, Leanne L. Cribbs and Kenneth L. Byron

  Molecular Pharmacology November 2009, 76 (5) 1053-1061; DOI: https://doi.org/10.1124/mol.109.057844
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  Vitamin D₃ and Its Nuclear Receptor Increase the Expression and Activity of the Human Proton-Coupled Folate Transporter

  Jyrki J. Eloranta, Zoulikha M. Zaïr, Christian Hiller, Stephanie Häusler, Bruno Stieger and Gerd A. Kullak-Ublick

  Molecular Pharmacology November 2009, 76 (5) 1062-1071; DOI: https://doi.org/10.1124/mol.109.055392
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  Three Epigenetic Drugs Up-Regulate Homeobox Gene Rhox5 in Cancer Cells through Overlapping and Distinct Molecular Mechanisms

  Qiang Li, David L. Bartlett, Michael C. Gorry, Mark E. O'Malley and Z. Sheng Guo

  Molecular Pharmacology November 2009, 76 (5) 1072-1081; DOI: https://doi.org/10.1124/mol.109.056291
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  Caveolin-1 and Lipid Microdomains Regulate G_s Trafficking and Attenuate G_s/Adenylyl Cyclase Signaling

  John A. Allen, Jiang Z. Yu, Rahul H. Dave, Anushree Bhatnagar, Bryan L. Roth and Mark M. Rasenick

  Molecular Pharmacology November 2009, 76 (5) 1082-1093; DOI: https://doi.org/10.1124/mol.109.060160
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  High-Throughput Screening Reveals a Small-Molecule Inhibitor of the Renal Outer Medullary Potassium Channel and Kir7.1

  L. Michelle Lewis, Gautam Bhave, Brian A. Chauder, Sreedatta Banerjee, Katharina A. Lornsen, Rey Redha, Katherine Fallen, Craig W. Lindsley, C. David Weaver and Jerod S. Denton

  Molecular Pharmacology November 2009, 76 (5) 1094-1103; DOI: https://doi.org/10.1124/mol.109.059840
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  Regulation of the CYP3A4 and CYP3A7 Promoters by Members of the Nuclear Factor I Transcription Factor Family

  Amanda K. Riffel, Eric Schuenemann and Carrie A. Vyhlidal

  Molecular Pharmacology November 2009, 76 (5) 1104-1114; DOI: https://doi.org/10.1124/mol.109.055699
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  Mechanisms Underlying Activation of Soluble Guanylate Cyclase by the Nitroxyl Donor Angeli's Salt

  Andreas Zeller, M. Verena Wenzl, Matteo Beretta, Heike Stessel, Michael Russwurm, Doris Koesling, Kurt Schmidt and Bernd Mayer

  Molecular Pharmacology November 2009, 76 (5) 1115-1122; DOI: https://doi.org/10.1124/mol.109.059915
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  Protein Kinase A and B-Raf Mediate Extracellular Signal-Regulated Kinase Activation by Thyrotropin

  Lisa A. Vuchak, Oxana M. Tsygankova, Gregory V. Prendergast and Judy L. Meinkoth

  Molecular Pharmacology November 2009, 76 (5) 1123-1129; DOI: https://doi.org/10.1124/mol.109.060129