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Molecular Pharmacology

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Table of Contents

December 01, 2009; Volume 76,Issue 6

MINIREVIEW

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    Agonists and Allosteric Modulators of the Calcium-Sensing Receptor and Their Therapeutic Applications
    Zuzana Saidak, Michel Brazier, Saïd Kamel and Romuald Mentaverri
    Molecular Pharmacology December 2009, 76 (6) 1131-1144; DOI: https://doi.org/10.1124/mol.109.058784

Accelerated Communication

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    Control of Glutamate Receptor 2 (GluR2) Translational Initiation by Its Alternative 3′ Untranslated Regions
    Hasan A. Irier, Yi Quan, Justin Yoo and Raymond Dingledine
    Molecular Pharmacology December 2009, 76 (6) 1145-1149; DOI: https://doi.org/10.1124/mol.109.060343

Articles

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    Regulation of Serotonin 1B Receptor by Glycogen Synthase Kinase-3
    Ligong Chen, Gregory D. Salinas and Xiaohua Li
    Molecular Pharmacology December 2009, 76 (6) 1150-1161; DOI: https://doi.org/10.1124/mol.109.056994
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    β-Arrestin-2 Interaction and Internalization of the Human P2Y1 Receptor Are Dependent on C-Terminal Phosphorylation Sites
    Susanne Reiner, Nicole Ziegler, Catherine Leon, Kristina Lorenz, Kathrin von Hayn, Christian Gachet, Martin J. Lohse and Carsten Hoffmann
    Molecular Pharmacology December 2009, 76 (6) 1162-1171; DOI: https://doi.org/10.1124/mol.109.060467
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    Influence of the Stereoisomeric Position of the Reactive Acetate Groups of the Benzo[b]Acronycine derivative S23906-1 on Its DNA Alkylation, Helix-Opening, Cytotoxic, and Antitumor Activities
    Sabine Depauw, Thomas Gaslonde, Stéphane Léonce, Laurence Kraus-Berthier, William Laine, Gaëlle Lenglet, Angèle Chiaroni, Bruno Pfeiffer, Christian Bailly, Sylvie Michel, François Tillequin, Alain Pierré and Marie-Hélène David-Cordonnier
    Molecular Pharmacology December 2009, 76 (6) 1172-1185; DOI: https://doi.org/10.1124/mol.109.057554
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    Urotensin II Induces Rat Cardiomyocyte Hypertrophy via the Transient Oxidization of Src Homology 2-Containing Tyrosine Phosphatase and Transactivation of Epidermal Growth Factor Receptor
    Ju-Chi Liu, Cheng-Hsien Chen, Jin-Jer Chen and Tzu-Hurng Cheng
    Molecular Pharmacology December 2009, 76 (6) 1186-1195; DOI: https://doi.org/10.1124/mol.109.058297
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    Subtype-Specific Differences in Corticotropin-Releasing Factor Receptor Complexes Detected by Fluorescence Spectroscopy
    Laura Milan-Lobo, Ingrid Gsandtner, Erwin Gaubitzer, Dominik Rünzler, Florian Buchmayer, Gottfried Köhler, Antonello Bonci, Michael Freissmuth and Harald H. Sitte
    Molecular Pharmacology December 2009, 76 (6) 1196-1210; DOI: https://doi.org/10.1124/mol.109.059139
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    Position 5.46 of the Serotonin 5-HT2A Receptor Contributes to a Species-Dependent Variation for the 5-HT2C Agonist (R)-9-Ethyl-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazino[2,1-a]isoindol-6(2H)-one: Impact on Selectivity and Toxicological Evaluation
    Keith J. Miller, Ginger Y. Wu, Jeffrey G. Varnes, Paul Levesque, Julia Li, Danshi Li, Jeffrey A. Robl, Karen A. Rossi and Dean A. Wacker
    Molecular Pharmacology December 2009, 76 (6) 1211-1219; DOI: https://doi.org/10.1124/mol.109.059204
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    Monoacylglycerol Lipase Limits the Duration of Endocannabinoid-Mediated Depolarization-Induced Suppression of Excitation in Autaptic Hippocampal Neurons
    Alex Straiker, Sherry Shu-Jung Hu, Jonathan Z. Long, Andy Arnold, Jim Wager-Miller, Benjamin F. Cravatt and Ken Mackie
    Molecular Pharmacology December 2009, 76 (6) 1220-1227; DOI: https://doi.org/10.1124/mol.109.059030
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    Activation of Retinoic Acid Receptors by Dihydroretinoids
    Alexander R. Moise, Susana Alvarez, Marta Domínguez, Rosana Alvarez, Marcin Golczak, Glenn P. Lobo, Johannes von Lintig, Angel R. de Lera and Krzysztof Palczewski
    Molecular Pharmacology December 2009, 76 (6) 1228-1237; DOI: https://doi.org/10.1124/mol.109.060038
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    An Anticancer Effect of Curcumin Mediated by Down-Regulating Phosphatase of Regenerating Liver-3 Expression on Highly Metastatic Melanoma Cells
    Lu Wang, Yan Shen, Ran Song, Yang Sun, Jianliang Xu and Qiang Xu
    Molecular Pharmacology December 2009, 76 (6) 1238-1245; DOI: https://doi.org/10.1124/mol.109.059105
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    Identification of Survival Genes in Human Glioblastoma Cells by Small Interfering RNA Screening
    Nikhil G. Thaker, Fang Zhang, Peter R. McDonald, Tong Ying Shun, Michael D. Lewen, Ian F. Pollack and John S. Lazo
    Molecular Pharmacology December 2009, 76 (6) 1246-1255; DOI: https://doi.org/10.1124/mol.109.058024
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    N Terminus of Type 5 Adenylyl Cyclase Scaffolds Gs Heterotrimer
    Rachna Sadana, Nathan Dascal and Carmen W. Dessauer
    Molecular Pharmacology December 2009, 76 (6) 1256-1264; DOI: https://doi.org/10.1124/mol.109.058370
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    NRF2 Cysteine Residues Are Critical for Oxidant/Electrophile-Sensing, Kelch-Like ECH-Associated Protein-1-Dependent Ubiquitination-Proteasomal Degradation, and Transcription Activation
    Xiaoqing He and Qiang Ma
    Molecular Pharmacology December 2009, 76 (6) 1265-1278; DOI: https://doi.org/10.1124/mol.109.058453
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    Receptor-Mediated Suppression of Potassium Currents Requires Colocalization within Lipid Rafts
    Susan Oldfield, Jane Hancock, Angharad Mason, Sally A. Hobson, David Wynick, Eamonn Kelly, Andrew D. Randall and Neil V. Marrion
    Molecular Pharmacology December 2009, 76 (6) 1279-1289; DOI: https://doi.org/10.1124/mol.109.058008
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    N6-Substituted cAMP Analogs Inhibit bTREK-1 K+ Channels and Stimulate Cortisol Secretion by a Protein Kinase A-Independent Mechanism
    Haiyan Liu, Judith A. Enyeart and John J. Enyeart
    Molecular Pharmacology December 2009, 76 (6) 1290-1301; DOI: https://doi.org/10.1124/mol.109.057075
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    Effects of Positive Allosteric Modulators on Single-Cell Oscillatory Ca2+ Signaling Initiated by the Type 5 Metabotropic Glutamate Receptor
    Sophie J. Bradley, Jeannette M. Watson and R. A. John Challiss
    Molecular Pharmacology December 2009, 76 (6) 1302-1313; DOI: https://doi.org/10.1124/mol.109.059170
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    KU135, a Novel Novobiocin-Derived C-Terminal Inhibitor of the 90-kDa Heat Shock Protein, Exerts Potent Antiproliferative Effects in Human Leukemic Cells
    Shary N. Shelton, Mary E. Shawgo, Shawna B. Matthews, Yuanming Lu, Alison C. Donnelly, Kristen Szabla, Mehmet Tanol, George A. Vielhauer, Roger A. Rajewski, Robert L. Matts, Brian S. J. Blagg and John D. Robertson
    Molecular Pharmacology December 2009, 76 (6) 1314-1322; DOI: https://doi.org/10.1124/mol.109.058545
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    P2X7 Receptor Activates Multiple Selective Dye-Permeation Pathways in RAW 264.7 and Human Embryonic Kidney 293 Cells
    Serife Cankurtaran-Sayar, Kemal Sayar and Mehmet Ugur
    Molecular Pharmacology December 2009, 76 (6) 1323-1332; DOI: https://doi.org/10.1124/mol.109.059923
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    Peroxisome Proliferator-Activated Receptor γ Antagonists Decrease Na+ Transport via the Epithelial Na+ Channel
    Tengis S. Pavlov, Vladislav Levchenko, Alexey V. Karpushev, Alain Vandewalle and Alexander Staruschenko
    Molecular Pharmacology December 2009, 76 (6) 1333-1340; DOI: https://doi.org/10.1124/mol.109.056911
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    Quantification of Gi-Mediated Inhibition of Adenylyl Cyclase Activity Reveals That UDP Is a Potent Agonist of the Human P2Y14 Receptor
    Rhonda L. Carter, Ingrid P. Fricks, Matthew O. Barrett, Lauren E. Burianek, Yixing Zhou, Hyojin Ko, Arijit Das, Kenneth A. Jacobson, Eduardo R. Lazarowski and T. Kendall Harden
    Molecular Pharmacology December 2009, 76 (6) 1341-1348; DOI: https://doi.org/10.1124/mol.109.058578
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    Phosphatidylinositol (4,5)-Bisphosphate Regulation of N-Methyl-d-aspartate Receptor Channels in Cortical Neurons
    Madhuchhanda Mandal and Zhen Yan
    Molecular Pharmacology December 2009, 76 (6) 1349-1359; DOI: https://doi.org/10.1124/mol.109.058701
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    The Basic Helix-Loop-Helix Proteins Differentiated Embryo Chondrocyte (DEC) 1 and DEC2 Function as Corepressors of Retinoid X Receptors
    Yoshitake Cho, Mitsuhide Noshiro, Mihwa Choi, Kentaro Morita, Takeshi Kawamoto, Katsumi Fujimoto, Yukio Kato and Makoto Makishima
    Molecular Pharmacology December 2009, 76 (6) 1360-1369; DOI: https://doi.org/10.1124/mol.109.057000
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In this issue

Molecular Pharmacology: 76 (6)
Molecular Pharmacology
Vol. 76, Issue 6
1 Dec 2009
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  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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