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Molecular Pharmacology

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Table of Contents

February 01, 2010; Volume 77,Issue 2

MINIREVIEWS

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    Structure and Function of Heterotrimeric G Protein-Regulated Rho Guanine Nucleotide Exchange Factors
    Mohamed Aittaleb, Cassandra A. Boguth and John J. G. Tesmer
    Molecular Pharmacology February 2010, 77 (2) 111-125; DOI: https://doi.org/10.1124/mol.109.061234
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    Is There a Future for Histone Deacetylase Inhibitors in the Pharmacotherapy of Psychiatric Disorders?
    Dennis R. Grayson, Marija Kundakovic and Rajiv P. Sharma
    Molecular Pharmacology February 2010, 77 (2) 126-135; DOI: https://doi.org/10.1124/mol.109.061333

Perspective

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    G Protein-Mediated Inhibition of Cav3.2 T-Type Channels Revisited
    Edward Perez-Reyes
    Molecular Pharmacology February 2010, 77 (2) 136-138; DOI: https://doi.org/10.1124/mol.109.062133

Articles

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    Analgesic ω-Conotoxins CVIE and CVIF Selectively and Voltage-Dependently Block Recombinant and Native N-Type Calcium Channels
    G. Berecki, L. Motin, A. Haythornthwaite, S. Vink, P. Bansal, R. Drinkwater, C. I. Wang, M. Moretta, R. J. Lewis, P. F. Alewood, M. J. Christie and D. J. Adams
    Molecular Pharmacology February 2010, 77 (2) 139-148; DOI: https://doi.org/10.1124/mol.109.058834
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    A Novel Multilevel Statistical Method for the Study of the Relationships between Multireceptorial Binding Affinity Profiles and In Vivo Endpoints
    Jana Selent, Anna Bauer-Mehren, Laura López, María Isabel Loza, Ferran Sanz and Manuel Pastor
    Molecular Pharmacology February 2010, 77 (2) 149-158; DOI: https://doi.org/10.1124/mol.109.060103
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    Identification of Novel Small-Molecule Agonists for Human Formyl Peptide Receptors and Pharmacophore Models of Their Recognition
    Liliya N. Kirpotina, Andrei I. Khlebnikov, Igor A. Schepetkin, Richard D. Ye, Marie-Josèphe Rabiet, Mark A. Jutila and Mark T. Quinn
    Molecular Pharmacology February 2010, 77 (2) 159-170; DOI: https://doi.org/10.1124/mol.109.060673
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    15-Hydroxyeicosatetraenoic Acid Is a Preferential Peroxisome Proliferator-Activated Receptor β/δ Agonist
    Simone Naruhn, Wolfgang Meissner, Till Adhikary, Kerstin Kaddatz, Thomas Klein, Bernhard Watzer, Sabine Müller-Brüsselbach and Rolf Müller
    Molecular Pharmacology February 2010, 77 (2) 171-184; DOI: https://doi.org/10.1124/mol.109.060541
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    Increased Spinal Dynorphin Levels and Phospho-Extracellular Signal-Regulated Kinases 1 and 2 and c-Fos Immunoreactivity after Surgery under Remifentanil Anesthesia in Mice
    Ana Campillo, Ana González-Cuello, David Cabañero, Paula Garcia-Nogales, Asunción Romero, M. Victoria Milanés, M. Luisa Laorden and Margarita M. Puig
    Molecular Pharmacology February 2010, 77 (2) 185-194; DOI: https://doi.org/10.1124/mol.109.059790
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    Aryl Hydrocarbon Receptor Regulates Cell Cycle Progression in Human Breast Cancer Cells via a Functional Interaction with Cyclin-Dependent Kinase 4
    Melissa A. Barhoover, Julie M. Hall, William F. Greenlee and Russell S. Thomas
    Molecular Pharmacology February 2010, 77 (2) 195-201; DOI: https://doi.org/10.1124/mol.109.059675
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    Protein Kinase C-Mediated Inhibition of Recombinant T-Type CaV3.2 Channels by Neurokinin 1 Receptors
    Azahel Rangel, Sergio Sánchez-Armass and Ulises Meza
    Molecular Pharmacology February 2010, 77 (2) 202-210; DOI: https://doi.org/10.1124/mol.109.058727
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    CCR2 Receptor Ligands Inhibit Cav3.2 T-Type Calcium Channels
    Haitao You, Christophe Altier and Gerald W Zamponi
    Molecular Pharmacology February 2010, 77 (2) 211-217; DOI: https://doi.org/10.1124/mol.109.059022
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    A Comparison of the Roles of Peroxisome Proliferator-Activated Receptor and Retinoic Acid Receptor on CYP26 Regulation
    Suzanne Tay, Leslie Dickmann, Vaishali Dixit and Nina Isoherranen
    Molecular Pharmacology February 2010, 77 (2) 218-227; DOI: https://doi.org/10.1124/mol.109.059071
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    The Benzenesulfoamide T0901317 [N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] Is a Novel Retinoic Acid Receptor-Related Orphan Receptor-α/γ Inverse Agonist
    Naresh Kumar, Laura A. Solt, Juliana J. Conkright, Yongjun Wang, Monica A. Istrate, Scott A. Busby, Ruben D. Garcia-Ordonez, Thomas P. Burris and Patrick R. Griffin
    Molecular Pharmacology February 2010, 77 (2) 228-236; DOI: https://doi.org/10.1124/mol.109.060905
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    The 5′-Untranslated Region of Multidrug Resistance Associated Protein 2 (MRP2; ABCC2) Regulates Downstream Open Reading Frame Expression through Translational Regulation
    Yuanyuan Zhang, Tianyong Zhao, Wei Li and Mary Vore
    Molecular Pharmacology February 2010, 77 (2) 237-246; DOI: https://doi.org/10.1124/mol.109.058982
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    Evidence for Ligand-Mediated Selective Modulation of Aryl Hydrocarbon Receptor Activity
    Iain A. Murray, Jose L. Morales, Colin A. Flaveny, Brett C. DiNatale, Chris Chiaro, Krishnegowda Gowdahalli, Shantu Amin and Gary H. Perdew
    Molecular Pharmacology February 2010, 77 (2) 247-254; DOI: https://doi.org/10.1124/mol.109.061788
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    A Novel Roscovitine Derivative Potently Induces G1-Phase Arrest in Platelet-Derived Growth Factor-BB-Activated Vascular Smooth Muscle Cells
    Irene M. Sroka, Elke H. Heiss, Libor Havlicek, Frank Totzke, Yasmin Aristei, Paul Pechan, Michael H. G. Kubbutat, Miroslav Strnad and Verena M. Dirsch
    Molecular Pharmacology February 2010, 77 (2) 255-261; DOI: https://doi.org/10.1124/mol.109.060327
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    Identification of Dynamin-2-Mediated Endocytosis as a New Target of Osteoporosis Drugs, Bisphosphonates
    Yuka Masaike, Takeshi Takagi, Masataka Hirota, Joe Yamada, Satoru Ishihara, Tetsu M. C. Yung, Takamasa Inoue, Chika Sawa, Hiroshi Sagara, Satoshi Sakamoto, Yasuaki Kabe, Yasuyuki Takahashi, Yuki Yamaguchi and Hiroshi Handa
    Molecular Pharmacology February 2010, 77 (2) 262-269; DOI: https://doi.org/10.1124/mol.109.059006
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    Dependence of Multidrug Resistance Protein-Mediated Cyclic Nucleotide Efflux on the Background Sodium Conductance
    Marek Kucka, Karla Kretschmannova, Takayo Murano, Chung-Pu Wu, Hana Zemkova, Suresh V. Ambudkar and Stanko S. Stojilkovic
    Molecular Pharmacology February 2010, 77 (2) 270-279; DOI: https://doi.org/10.1124/mol.109.059386
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    An Inhibitor of Protein Arginine Methyltransferases, 7,7′-Carbonylbis(azanediyl)bis(4-hydroxynaphthalene-2-sulfonic acid (AMI-1), Is a Potent Scavenger of NADPH-Oxidase–Derived Superoxide
    Feng Chen and David J. R. Fulton
    Molecular Pharmacology February 2010, 77 (2) 280-287; DOI: https://doi.org/10.1124/mol.109.061077
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    Role of Helix 8 of the Thyrotropin-Releasing Hormone Receptor in Phosphorylation by G Protein-Coupled Receptor Kinase
    Austin U. Gehret, Brian W. Jones, Phuong N. Tran, Laurie B. Cook, Emileigh K. Greuber and Patricia M. Hinkle
    Molecular Pharmacology February 2010, 77 (2) 288-297; DOI: https://doi.org/10.1124/mol.109.059733
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    Cisplatin Enhances Protein Kinase R-Like Endoplasmic Reticulum Kinase- and CD95-Dependent Melanoma Differentiation-Associated Gene-7/Interleukin-24–Induced Killing in Ovarian Carcinoma Cells
    Adly Yacoub, Renyan Liu, Margaret A. Park, Hossein A. Hamed, Rupesh Dash, Danielle N. Schramm, Devanand Sarkar, Igor P. Dimitriev, Jessica K. Bell, Steven Grant, Nicholas P. Farrell, David T. Curiel, Paul B. Fisher and Paul Dent
    Molecular Pharmacology February 2010, 77 (2) 298-310; DOI: https://doi.org/10.1124/mol.109.061820
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    Dependence on the Microtubule Network and 90-kDa Heat Shock Protein of Phenobarbital-Induced Nuclear Translocation of the Rat Constitutive Androstane Receptor
    Yuichiro Kanno, Yasuo Miyama, Mina Ando and Yoshio Inouye
    Molecular Pharmacology February 2010, 77 (2) 311-316; DOI: https://doi.org/10.1124/mol.109.060434
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In this issue

Molecular Pharmacology: 77 (2)
Molecular Pharmacology
Vol. 77, Issue 2
1 Feb 2010
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Back Matter (PDF)
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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