Table of Contents

Articles

• You have access

  Genetic Deletion of p90 Ribosomal S6 Kinase 2 Alters Patterns of 5-Hydroxytryptamine_2A Serotonin Receptor Functional Selectivity

  Ryan T. Strachan, Noah Sciaky, Mark R. Cronan, Wesley K. Kroeze and Bryan L. Roth

  Molecular Pharmacology March 2010, 77 (3) 327-338; DOI: https://doi.org/10.1124/mol.109.061440
• You have access

  Phosphorylation of the μ-Opioid Receptor at Tyrosine 166 (Tyr3.51) in the DRY Motif Reduces Agonist Efficacy

  Cecilea C. Clayton, Michael R. Bruchas, Michael L. Lee and Charles Chavkin

  Molecular Pharmacology March 2010, 77 (3) 339-347; DOI: https://doi.org/10.1124/mol.109.060558
• You have access

  Pleiotropic Effects of YC-1 Selectively Inhibit Pathological Retinal Neovascularization and Promote Physiological Revascularization in a Mouse Model of Oxygen-Induced Retinopathy

  M. DeNiro, A. Al-Halafi, F. H. Al-Mohanna, O. Alsmadi and F. A. Al-Mohanna

  Molecular Pharmacology March 2010, 77 (3) 348-367; DOI: https://doi.org/10.1124/mol.109.061366
• You have access

  Simple 2,4-Diacylphloroglucinols as Classic Transient Receptor Potential-6 Activators—Identification of a Novel Pharmacophore

  K. Leuner, J. H. Heiser, S. Derksen, M. I. Mladenov, C. J. Fehske, R. Schubert, M. Gollasch, G. Schneider, C. Harteneck, S. S. Chatterjee and W. E. Müller

  Molecular Pharmacology March 2010, 77 (3) 368-377; DOI: https://doi.org/10.1124/mol.109.057513
• You have access

  Tirucallic Acids Are Novel Pleckstrin Homology Domain-Dependent Akt Inhibitors Inducing Apoptosis in Prostate Cancer Cells

  Aydee C. Estrada, Tatiana Syrovets, Kai Pitterle, Oleg Lunov, Berthold Büchele, Judith Schimana-Pfeifer, Thomas Schmidt, Samy A. F. Morad and Thomas Simmet

  Molecular Pharmacology March 2010, 77 (3) 378-387; DOI: https://doi.org/10.1124/mol.109.060475
• You have access

  The Small GTPase Ral Couples the Angiotensin II Type 1 Receptor to the Activation of Phospholipase C-δ1

  Christina M. Godin, Lucimar T. Ferreira, Lianne B. Dale, Robert Gros, Sean P. Cregan and Stephen S. G. Ferguson

  Molecular Pharmacology March 2010, 77 (3) 388-395; DOI: https://doi.org/10.1124/mol.109.061069
• You have access

  Activation of Nerve Growth Factor-Induced Bα by Methylene-Substituted Diindolylmethanes in Bladder Cancer Cells Induces Apoptosis and Inhibits Tumor Growth

  Sung Dae Cho, Syng-Ook Lee, Sudhakar Chintharlapalli, Maen Abdelrahim, Shaheen Khan, Kyungsil Yoon, Ashish M. Kamat and Stephen Safe

  Molecular Pharmacology March 2010, 77 (3) 396-404; DOI: https://doi.org/10.1124/mol.109.061143
• You have access

  Role for the Regulator of G-Protein Signaling Homology Domain of G Protein-Coupled Receptor Kinases 5 and 6 in β2-Adrenergic Receptor and Rhodopsin Phosphorylation

  Faiza Baameur, Daniel H. Morgan, Hui Yao, Tuan M. Tran, Richard A. Hammitt, Subir Sabui, John S. McMurray, Olivier Lichtarge and Richard B. Clark

  Molecular Pharmacology March 2010, 77 (3) 405-415; DOI: https://doi.org/10.1124/mol.109.058115
• You have access

  Acquired Activation of the Akt/Cyclooxygenase-2/Mcl-1 Pathway Renders Lung Cancer Cells Resistant to Apoptosis

  Wenjie Chen, Lang Bai, Xia Wang, Shanling Xu, Steven A. Belinsky and Yong Lin

  Molecular Pharmacology March 2010, 77 (3) 416-423; DOI: https://doi.org/10.1124/mol.109.061226
• You have access

  Long-Term Fluoxetine Treatment Modulates Cannabinoid Type 1 Receptor-Mediated Inhibition of Adenylyl Cyclase in the Rat Prefrontal Cortex through 5-Hydroxytryptamine_1A Receptor-Dependent Mechanisms

  Susana Mato, Rebeca Vidal, Elena Castro, Álvaro Díaz, Ángel Pazos and Elsa M. Valdizán

  Molecular Pharmacology March 2010, 77 (3) 424-434; DOI: https://doi.org/10.1124/mol.109.060079
• You have access

  Phosphatidylinositol 3,4,5-Triphosphate-Dependent Rac Exchanger 1 (P-Rex-1), a Guanine Nucleotide Exchange Factor for Rac, Mediates Angiogenic Responses to Stromal Cell-Derived Factor-1/Chemokine Stromal Cell Derived Factor-1 (SDF-1/CXCL-12) Linked to Rac Activation, Endothelial Cell Migration, and in Vitro Angiogenesis

  Jorge Carretero-Ortega, Colin T. Walsh, Ricardo Hernández-García, Guadalupe Reyes-Cruz, Joan Heller Brown and José Vázquez-Prado

  Molecular Pharmacology March 2010, 77 (3) 435-442; DOI: https://doi.org/10.1124/mol.109.060400
• You have access

  Iron Chelator-Mediated Alterations in Gene Expression: Identification of Novel Iron-Regulated Molecules That Are Molecular Targets of Hypoxia-Inducible Factor-1α and p53

  Federica Saletta, Yohan Suryo Rahmanto, Egarit Noulsri and Des R. Richardson

  Molecular Pharmacology March 2010, 77 (3) 443-458; DOI: https://doi.org/10.1124/mol.109.061028
• You have access

  Context-Dependent Pharmacology Exhibited by Negative Allosteric Modulators of Metabotropic Glutamate Receptor 7

  Colleen M. Niswender, Kari A. Johnson, Nicole R. Miller, Jennifer E. Ayala, Qingwei Luo, Richard Williams, Samir Saleh, Darren Orton, C. David Weaver and P. Jeffrey Conn

  Molecular Pharmacology March 2010, 77 (3) 459-468; DOI: https://doi.org/10.1124/mol.109.058768
• You have access

  cAMP Analogs and Their Metabolites Enhance TREK-1 mRNA and K⁺ Current Expression in Adrenocortical Cells

  Judith A. Enyeart, Haiyan Liu and John J. Enyeart

  Molecular Pharmacology March 2010, 77 (3) 469-482; DOI: https://doi.org/10.1124/mol.109.061861
• You have access

  The Bcl-2 Homology Domain 3 Mimetic ABT-737 Targets the Apoptotic Machinery in Acute Lymphoblastic Leukemia Resulting in Synergistic in Vitro and in Vivo Interactions with Established Drugs

  Laura M. High, Barbara Szymanska, Urszula Wilczynska-Kalak, Nicole Barber, Rosemary O'Brien, Seong Lin Khaw, Ingela B. Vikstrom, Andrew W. Roberts and Richard B. Lock

  Molecular Pharmacology March 2010, 77 (3) 483-494; DOI: https://doi.org/10.1124/mol.109.060780